Objective: To prospectively evaluate the prognostic value of seminal anti-sperm antibodies screen... more Objective: To prospectively evaluate the prognostic value of seminal anti-sperm antibodies screening in couples prepared for intracytoplasmic sperm injection.Methods: A prospective comparative study was conducted, including 184 non-azoospermic infertile men scheduled for ICSI. For each patient, detection of anti-sperm antibodies in seminal plasma using ELISA technique was done and its relation to standard semen parameters and ICSI outcomes, including fertilization, embryo development, and pregnancy rates, were analyzed.Results: Sperm count, motility, and morphology were negatively affected by existence of seminal ASA (p=0.012, 0.006, and 0.011, respectively). However, no statistically significant difference was detected between patients with positive and negative seminal ASA regarding the median values of fertilization (56.3% Vs. 66.7%, p =0.091), percentage of couples with grade A embryo development (91.4% vs. 89.9%, p= 0.520), and pregnancy rates (31.4% vs. 32.2%, p =0.98) after I...
Objective: To evaluate results of surgical intervention in patients with chronic obstructive rena... more Objective: To evaluate results of surgical intervention in patients with chronic obstructive renal failure. We will try to assess some of the factors that may predict favorable outcomes. Patients and methods: Eighty six patients diagnosed clinically as having chronic obstructive renal failure (53 men 61.63% and 33 women 38.37% ranging in age between 25 and 69 years, mean 47 years) in the period from September 2010 to August 2012. The patients on this study were divided according to past history of renal impairment and/or regular dialysis into two groups as follow: Group (A): Patients with chronic renal failure with no regular dialysis (46 patients) Males: 28 (60.86%) Females: 18 (39.14%). Group (B): Patients with chronic renal failure with regular dialysis (40 patients) Males: 25 (62.5%) Females: 15 (37.5%). All patients have been evaluated according to the protocol of obstructive uropathy. Clinically most patients presented by anuria 28 (32.65%) patients (16 group A and 12 group B)...
While long non-coding RNA (lncRNA) genes have attracted a lot of attention in the last decade, th... more While long non-coding RNA (lncRNA) genes have attracted a lot of attention in the last decade, the focus regarding their mechanisms of action has been primarily on the RNA product of these genes. Recent work on several lncRNAs genes demonstrates that not only is the produced RNA species important, but also that transcription of the lncRNA locus alone can have regulatory functions. Like the functions of lncRNA transcripts, the mechanisms that underlie these genome-based functions are varied. Here we highlight some of these examples and provide an outlook on how the functional mechanisms of a lncRNA gene can be determined.
Clock is repeated every clock repeating distance and dropped-off in data repeaters Clk & Data Rep... more Clock is repeated every clock repeating distance and dropped-off in data repeaters Clk & Data Repeater Cable Section Cable Section CMU Data RX/TX
The invention relates to a common mode termination with a C-multiplier circuit. Embodiments of th... more The invention relates to a common mode termination with a C-multiplier circuit. Embodiments of the present disclosure provide input termination circuits that overcome the deficiencies of conventional designs. Specifically, embodiments eliminate large-on chip bypass capacitors that are commonly used for common mode termination, and instead use an active capacitor-multiplier (C-multiplier) circuit at the common mode node. The C-multiplier circuit mimics a large capacitor at high frequency. By eliminating large on-chip bypass capacitors, the IC design (e.g., receiver) is reduced in size, without affecting common mode return loss performance. Embodiments may be used with any applications that require input termination, and particularly with differential applications that require common mode termination.
International Journal of Electrochemical Science, Jan 19, 2015
A simple, rapid and sensitive method for the determination of mebeverine hydrochloride (MBHCl) in... more A simple, rapid and sensitive method for the determination of mebeverine hydrochloride (MBHCl) in urine, serum and pharmaceutical preparations using modified carbon paste electrodes was developed. The electrochemical sensors showed a linear dynamic range of 3.0 × 10-7-1.0 × 10-2 and 1.0 × 10-7-1.0 × 10-2 mol L-1 with detection limit of 3.0×10-7 and 1×10-7 mol L-1 for modified carbon paste (MCPEs; sensors I and II), respectively. The slopes of the calibration graphs are 56.78±0.85 and 58.80±0.46 mV decade-1 for MCPEs with tricresylphosphate (TCP) (sensor I) and onitrophenyloctylether (o-NPOE) (sensor II) as plasticizers, respectively. The response time was relatively quick in the whole concentration range (8 and 7 s), respectively. The electrodes can be used at least 65 and 73 days without observing any deviations in a pH range of 2.0-8.0 and 1.5-8.0 for electrodes I and II, respectively. The fabricated electrodes displayed good selectivity for MBHCl with respect to number of common foreign inorganic cations, sugar species, and glycine as the fillers that may be added to the pharmaceutical preparation. Fortunately, such materials mostly do not interfere. The sensors were successfully applied for the determination of MBHCl in its tablets, urine and serum. The results obtained using these potentiometric electrodes were comparable with those obtained using official method.
Embodiments of the present invention enable bandwidth extension of receiver front-end circuits wi... more Embodiments of the present invention enable bandwidth extension of receiver front-end circuits without the use of inductors. As a result, significantly smaller and cheaper receivers can be made. In an embodiment, bandwidth extension is achieved by very small floating capacitors that are coupled around amplifier stages of the receiver front-end circuit. Each of the capacitors is configured to generate a negative capacitance for the preceding stage (e.g., equalizer or amplifier), thus extending the bandwidth of the preceding stage. A capacitively-degenerated crosscoupled transistor pair allows bandwidth extension for the final (e.g., amplifier) stage. Embodiments further enable DC offset compensation with the use of a digital feedback loop. The feedback loop can thus be turned on/off as needed, reducing power consumption. [Reference numerals] (AA) To other circuitry, e.g., slicers
Potentiometric determination of La(III) in polluted water samples using modified screen-printed e... more Potentiometric determination of La(III) in polluted water samples using modified screen-printed electrode by self-assembled mercapto compound on silver nanoparticles
ABSTRACT Energy harvesting from environmental vibration nowadays is feasible because of natural o... more ABSTRACT Energy harvesting from environmental vibration nowadays is feasible because of natural oscillations like that caused by air or liquid flow and by exhalation or the heartbeat of a human body. This vibration frequency is typically low (in order of less than 1 kHz). Accordingly, low frequency vibration based energy harvesting systems are an important research topic; these systems can be used for wearable or implantable devices. Piezoelectric vibration based harvesters are not expensive and do not require external voltage sources, making them a viable alternative to implement energy harvesting system. In this paper a macro-scale unimorph piezoelectric cantilever with non-traditional geometry is investigated for generation of electrical energy by using the software COMSOL Multiphysics 4.4 FEA. The piezoelectric energy harvester consists of an active piezoelectric layer (PZT-5H), steel substrate and titanium proof mass. The proposed structure is simulated and the results are compared with other traditional geometries. Simulation results demonstrated that the new cantilever structure has a lower resonance frequency and higher average strain than the rectangular structures, which makes it suitable for wearable or implantable devices.
ABSTRACT A pad driver is presented that in one form is capable of driving a wide range of capacit... more ABSTRACT A pad driver is presented that in one form is capable of driving a wide range of capacitive loads with constant rise and fall times, over a Wide range of temperature and process comers. A desirable form of the pad driver is characterized by the ability to charge and discharge rail-to-rail with a constant charging and discharging rate over the whole charging and discharging cycles. Furthermore, desirably the driver is independent of any load present at the output pad.
A SerDes operating from 8.5 to 11.4 Gb/s using nearly all CMOS digital circuits is presented. The... more A SerDes operating from 8.5 to 11.4 Gb/s using nearly all CMOS digital circuits is presented. The transmitter achieves up to 1 Vdpp output swing with a DDJ as low as 2.7 ps. The receiver achieves an input sensitivity of less than 17 mVdpp. The chip is capable of transmitting and receiving data on an FR4 channel with 21 dB loss at Nyquist at a BER <; 10-12. The power consumption per Tx/Rx pair is 28.5 mW, and the active area is 0.047 mm2 in 28 nm CMOS. The chip reports the minimum SerDes area in the published literature.
Objective: To prospectively evaluate the prognostic value of seminal anti-sperm antibodies screen... more Objective: To prospectively evaluate the prognostic value of seminal anti-sperm antibodies screening in couples prepared for intracytoplasmic sperm injection.Methods: A prospective comparative study was conducted, including 184 non-azoospermic infertile men scheduled for ICSI. For each patient, detection of anti-sperm antibodies in seminal plasma using ELISA technique was done and its relation to standard semen parameters and ICSI outcomes, including fertilization, embryo development, and pregnancy rates, were analyzed.Results: Sperm count, motility, and morphology were negatively affected by existence of seminal ASA (p=0.012, 0.006, and 0.011, respectively). However, no statistically significant difference was detected between patients with positive and negative seminal ASA regarding the median values of fertilization (56.3% Vs. 66.7%, p =0.091), percentage of couples with grade A embryo development (91.4% vs. 89.9%, p= 0.520), and pregnancy rates (31.4% vs. 32.2%, p =0.98) after I...
Objective: To evaluate results of surgical intervention in patients with chronic obstructive rena... more Objective: To evaluate results of surgical intervention in patients with chronic obstructive renal failure. We will try to assess some of the factors that may predict favorable outcomes. Patients and methods: Eighty six patients diagnosed clinically as having chronic obstructive renal failure (53 men 61.63% and 33 women 38.37% ranging in age between 25 and 69 years, mean 47 years) in the period from September 2010 to August 2012. The patients on this study were divided according to past history of renal impairment and/or regular dialysis into two groups as follow: Group (A): Patients with chronic renal failure with no regular dialysis (46 patients) Males: 28 (60.86%) Females: 18 (39.14%). Group (B): Patients with chronic renal failure with regular dialysis (40 patients) Males: 25 (62.5%) Females: 15 (37.5%). All patients have been evaluated according to the protocol of obstructive uropathy. Clinically most patients presented by anuria 28 (32.65%) patients (16 group A and 12 group B)...
While long non-coding RNA (lncRNA) genes have attracted a lot of attention in the last decade, th... more While long non-coding RNA (lncRNA) genes have attracted a lot of attention in the last decade, the focus regarding their mechanisms of action has been primarily on the RNA product of these genes. Recent work on several lncRNAs genes demonstrates that not only is the produced RNA species important, but also that transcription of the lncRNA locus alone can have regulatory functions. Like the functions of lncRNA transcripts, the mechanisms that underlie these genome-based functions are varied. Here we highlight some of these examples and provide an outlook on how the functional mechanisms of a lncRNA gene can be determined.
Clock is repeated every clock repeating distance and dropped-off in data repeaters Clk & Data Rep... more Clock is repeated every clock repeating distance and dropped-off in data repeaters Clk & Data Repeater Cable Section Cable Section CMU Data RX/TX
The invention relates to a common mode termination with a C-multiplier circuit. Embodiments of th... more The invention relates to a common mode termination with a C-multiplier circuit. Embodiments of the present disclosure provide input termination circuits that overcome the deficiencies of conventional designs. Specifically, embodiments eliminate large-on chip bypass capacitors that are commonly used for common mode termination, and instead use an active capacitor-multiplier (C-multiplier) circuit at the common mode node. The C-multiplier circuit mimics a large capacitor at high frequency. By eliminating large on-chip bypass capacitors, the IC design (e.g., receiver) is reduced in size, without affecting common mode return loss performance. Embodiments may be used with any applications that require input termination, and particularly with differential applications that require common mode termination.
International Journal of Electrochemical Science, Jan 19, 2015
A simple, rapid and sensitive method for the determination of mebeverine hydrochloride (MBHCl) in... more A simple, rapid and sensitive method for the determination of mebeverine hydrochloride (MBHCl) in urine, serum and pharmaceutical preparations using modified carbon paste electrodes was developed. The electrochemical sensors showed a linear dynamic range of 3.0 × 10-7-1.0 × 10-2 and 1.0 × 10-7-1.0 × 10-2 mol L-1 with detection limit of 3.0×10-7 and 1×10-7 mol L-1 for modified carbon paste (MCPEs; sensors I and II), respectively. The slopes of the calibration graphs are 56.78±0.85 and 58.80±0.46 mV decade-1 for MCPEs with tricresylphosphate (TCP) (sensor I) and onitrophenyloctylether (o-NPOE) (sensor II) as plasticizers, respectively. The response time was relatively quick in the whole concentration range (8 and 7 s), respectively. The electrodes can be used at least 65 and 73 days without observing any deviations in a pH range of 2.0-8.0 and 1.5-8.0 for electrodes I and II, respectively. The fabricated electrodes displayed good selectivity for MBHCl with respect to number of common foreign inorganic cations, sugar species, and glycine as the fillers that may be added to the pharmaceutical preparation. Fortunately, such materials mostly do not interfere. The sensors were successfully applied for the determination of MBHCl in its tablets, urine and serum. The results obtained using these potentiometric electrodes were comparable with those obtained using official method.
Embodiments of the present invention enable bandwidth extension of receiver front-end circuits wi... more Embodiments of the present invention enable bandwidth extension of receiver front-end circuits without the use of inductors. As a result, significantly smaller and cheaper receivers can be made. In an embodiment, bandwidth extension is achieved by very small floating capacitors that are coupled around amplifier stages of the receiver front-end circuit. Each of the capacitors is configured to generate a negative capacitance for the preceding stage (e.g., equalizer or amplifier), thus extending the bandwidth of the preceding stage. A capacitively-degenerated crosscoupled transistor pair allows bandwidth extension for the final (e.g., amplifier) stage. Embodiments further enable DC offset compensation with the use of a digital feedback loop. The feedback loop can thus be turned on/off as needed, reducing power consumption. [Reference numerals] (AA) To other circuitry, e.g., slicers
Potentiometric determination of La(III) in polluted water samples using modified screen-printed e... more Potentiometric determination of La(III) in polluted water samples using modified screen-printed electrode by self-assembled mercapto compound on silver nanoparticles
ABSTRACT Energy harvesting from environmental vibration nowadays is feasible because of natural o... more ABSTRACT Energy harvesting from environmental vibration nowadays is feasible because of natural oscillations like that caused by air or liquid flow and by exhalation or the heartbeat of a human body. This vibration frequency is typically low (in order of less than 1 kHz). Accordingly, low frequency vibration based energy harvesting systems are an important research topic; these systems can be used for wearable or implantable devices. Piezoelectric vibration based harvesters are not expensive and do not require external voltage sources, making them a viable alternative to implement energy harvesting system. In this paper a macro-scale unimorph piezoelectric cantilever with non-traditional geometry is investigated for generation of electrical energy by using the software COMSOL Multiphysics 4.4 FEA. The piezoelectric energy harvester consists of an active piezoelectric layer (PZT-5H), steel substrate and titanium proof mass. The proposed structure is simulated and the results are compared with other traditional geometries. Simulation results demonstrated that the new cantilever structure has a lower resonance frequency and higher average strain than the rectangular structures, which makes it suitable for wearable or implantable devices.
ABSTRACT A pad driver is presented that in one form is capable of driving a wide range of capacit... more ABSTRACT A pad driver is presented that in one form is capable of driving a wide range of capacitive loads with constant rise and fall times, over a Wide range of temperature and process comers. A desirable form of the pad driver is characterized by the ability to charge and discharge rail-to-rail with a constant charging and discharging rate over the whole charging and discharging cycles. Furthermore, desirably the driver is independent of any load present at the output pad.
A SerDes operating from 8.5 to 11.4 Gb/s using nearly all CMOS digital circuits is presented. The... more A SerDes operating from 8.5 to 11.4 Gb/s using nearly all CMOS digital circuits is presented. The transmitter achieves up to 1 Vdpp output swing with a DDJ as low as 2.7 ps. The receiver achieves an input sensitivity of less than 17 mVdpp. The chip is capable of transmitting and receiving data on an FR4 channel with 21 dB loss at Nyquist at a BER <; 10-12. The power consumption per Tx/Rx pair is 28.5 mW, and the active area is 0.047 mm2 in 28 nm CMOS. The chip reports the minimum SerDes area in the published literature.
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