Papers by Serhat Koseoglu
Case Reports in Dentistry, 2015
Purpose. As documented in the literature, bony defects can be managed by an orthodontic approach.... more Purpose. As documented in the literature, bony defects can be managed by an orthodontic approach. Methods. This case report describes the treatment of a bony defect caused by orthodontic malposition through phase I periodontal therapy and a simple removable orthodontic appliance used for the first time in a 20-year-old girl. Results. The periodontal pocket was reduced from 8 mm to 3 mm shortly after treatment. Conclusion. This case report concludes that orthodontic therapy can be used successfully in treatment of bony defects caused by mesially tilted molars.
PloS one, 2015
The purpose of this animal study was to evaluate the effects of hawthorn (Crataeus orientalis M B... more The purpose of this animal study was to evaluate the effects of hawthorn (Crataeus orientalis M Bieber.) extract on serum oxidative status and alveolar bone loss in experimental periodontitis. Twenty-seven Wistar rats were assigned to one of the following groups: non- ligated+placebo (saline) (NL, n = 9), ligature only+placebo (saline) (LO, n = 9), and ligature and treated with hawthorn extract in saline (H, n = 9) (100 mg/kg orogastrically, once a day for 11 days). Periodontitis was induced by submerging a 4/0 silk ligature in the sulcus of the mandibular right first molars of rats, and the animals were sacrificed after 11 days. Micro-CT examinations were performed for linear and volumetric parameter assessment of alveolar bone. Periodontal tissues were histopathologically examined to assess the differences among the study groups. Levels of serum total antioxidant status (TAS)/total oxidant status (TOS), and oxidative stress index (OSI) were also analyzed. Alveolar bone loss was si...
The etiology of internal root resorption is not fully understandable. Trauma and chronic pulpitis... more The etiology of internal root resorption is not fully understandable. Trauma and chronic pulpitis are considered the main risk factors. Usually the internal root resorption is asymptomatic and diagnosed upon routine radiographic examination. A 30-year-old male arrived at the clinic with complaints of pain at the night and swelling after the composite restoration in tooth 12. Radiographic examination revealed internal resorptions in teeth 12 and 21. The resorptif cavities were confirmed by evaluation with cone beam computed tomography. Root canal treatment was performed on three teeth; however in spite of the all attempts, the apical third of the tooth 12 was not achieved. Thus, the treatment strategy was changed and it was decided to perform a surgical approach on the tooth 12. This case report presents the ortograde approach to internal resorptions in teeth 11 and 21, and retrograde approach in tooth 12.
Case reports in dentistry, 2015
This case report presents two cases of delayed replantation of avulsed maxillary central incisors... more This case report presents two cases of delayed replantation of avulsed maxillary central incisors after an extended dry extra-alveolar period. Eight-year-old boy and 10-year-old boy presented with avulsed maxillary central incisors due to trauma occurring 27 and 7 hours earlier, respectively. Treatment guidelines for avulsed mature/immature permanent teeth with prolonged extra-oral time were carried out for the teeth and the extra-oral endodontic treatment was completed. After having been repositioned, the teeth were stabilized for 4 weeks and prophylactic antibiotic was prescribed. Clinical and radiographic controls were done after 18 months for Case I and 12 months for Case II. During the follow-up periods the teeth reported in these cases have remained in a stable, functional position but revealed clinical initial replacement resorption and ankylosis.
Journal of periodontology, Jan 19, 2015
A novel member of the interleukin (IL)-12 family, IL-35 is an important inhibitory cytokine relea... more A novel member of the interleukin (IL)-12 family, IL-35 is an important inhibitory cytokine released by regulatory T (Treg) cells. The aim of the study is to evaluate gingival crevicular fluid (GCF), saliva and plasma levels of IL-35 in periodontal disease and health. Samples of GCF, whole saliva and plasma were obtained from systemically healthy, non-smoker individuals with gingivitis (n=20), chronic periodontitis (CP) (n=20), and periodontally healthy (n=20). Full-mouth clinical periodontal measurements including probing depth (PD), bleeding on probing (BOP), gingival index (GI) and plaque index (PI) were also recorded. Enzyme-linked immunosorbent assay (ELISA) was used to determine IL-35 levels in the samples. Data were tested statistically by ANOVA and Pearson rank correlation test. All clinical parameters were significantly higher in the CP group than the healthy and gingivitis groups (P<0.001). The GCF total amount of IL-35 was significantly higher in the CP group than the ...
Journal of applied oral science : revista FOB
Objectives Sumac (Rhus coriaria L.) is widely used spice which has several properties such as ant... more Objectives Sumac (Rhus coriaria L.) is widely used spice which has several properties such as antioxidant, anti-inflammatory and antimicrobial. The purpose of this animal study was to evaluate the effects of sumac extract on levels of receptor activator of nuclear factor-kappa B ligand (RANKL), osteoprotegerin (OPG) expression, serum oxidative status, and alveolar bone loss in experimental periodontitis. Material and Methods Twenty-four Wistar rats were separated into three groups: non-ligated (NL, n=8), ligature only (LO, n=8), and ligature and treated with sumac extract (S, n=8) (20 mg/kg per day for 11 days). A 4/0 silk suture was placed around the mandibular right first molars subgingivally; after 11 days, the rats were sacrificed, and alveolar bone loss was histometrically measured. The detection of RANKL and OPG were immunohistochemically performed. Levels of serum total antioxidant status (TAS)/total oxidant status (TOS), and oxidative stress index (OSI) were also analyzed. R...
Journal of Periodontology, 2013
Gingival recession (GR) is one of the most common esthetic concerns associated with periodontal t... more Gingival recession (GR) is one of the most common esthetic concerns associated with periodontal tissues. Recently, tissue engineering technology has been developed and applied in periodontology for the treatment of GR. The aim of this study is to compare the clinical efficacy of collagen membrane with or without autologous gingival fibroblasts under a coronally advanced flap for root coverage. In this split-mouth, controlled clinical study, 22 sites are selected from 11 patients with Miller Class I recessions affecting canines or premolars in the maxillary arch. One tooth in each patient was randomized to receive either a collagen membrane (CM) (control group) or a collagen membrane seeded with autologous gingival fibroblasts (CM+GF) (test group) under a coronally advanced flap. Thickness of the gingiva, GR, and percentage of root coverage (PRC) were recorded by a calibrated examiner at baseline and 3, 6, and 12 months postoperatively. Furthermore, GR and PRC were evaluated using photogrammetric analysis at baseline and 3, 6, and 12 months. Both treatments resulted in a significant gain in root coverage compared with baseline. A statistically significant increase was detected in PRC in the test group compared with the control group. No significant difference was noted between the test and control sites regarding the thickness of the gingiva. The results indicated that CM+GF prepared by tissue engineering technology can be considered an alternative method for the treatment of Miller Class I recession defects.
Journal of clinical periodontology, Jan 16, 2015
Evaluating effectiveness of a medicinal plant extract (MPE) in achieving haemostasis and early wo... more Evaluating effectiveness of a medicinal plant extract (MPE) in achieving haemostasis and early wound healing at free gingival graft (FGG) donor site in a randomized controlled fashion. 40 patients requiring FGG at lower anterior area were randomly assigned into two groups. FGG was performed to all patients and following graft procurement; wet gauze was applied alone (control: WG group) or with MPE (test: MPE+WG group) for haemostasis. Donor site working time, bleeding (BLE), colour match (CM), pain, epithelization (EP) and sensation loss (SL) were evaluated. 33 participants completed six months period. In test group, primary BLE was shorter (p<0.001) and fewer individuals showed secondary BLE during three days (p<0.001). During six days, pain scores were higher in WG patients (p<0.05). Later on, no intergroup difference was observed. EP was relatively faster (p<0.001) and CM was slightly better (p<0.05) in MPE+WG group. MPE provided faster and continuous haemostasis t...
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Papers by Serhat Koseoglu