Asian Pacific journal of allergy and immunology / launched by the Allergy and Immunology Society of Thailand
Certain occupational groups are known to be at particularly high risk of developing allergic dise... more Certain occupational groups are known to be at particularly high risk of developing allergic diseases. The objective of the present study was to evaluate the prevalence of allergic diseases among working adolescents. The International Study of Asthma and Allergies in Childhood questionnaire was used. Four hundred and thirty six adolescents working in motor, lathe-finish, coiffure and textile and 366 high school students as control group were enrolled to the study. Mean age was 16.8 +/- 1.2 years and 82.9% of them were male. There was no significant difference among groups for ever and current wheezing while doctor diagnosed asthma was higher in lathe- finish group (p = 0.036). Family history of allergy, history of allergic rhinitis, and active smoking were found to be risk factors for asthma and related symptoms. Working in coiffure (p = 0.054), and textile (p = 0.003) were significant risk factors for ever allergic rhinitis. Working in lathe finish (p = 0.023), coiffure (p = .002),...
Bu yazıda kronik ishal, tekrarlayan hışıltılı solunum atakları, sık solunum yolu enfeksiyonu, par... more Bu yazıda kronik ishal, tekrarlayan hışıltılı solunum atakları, sık solunum yolu enfeksiyonu, parmaklarda çomaklaşma ve büyüme geriliği bulunan 10 yaşında bir olgu sunulmuştur. Vakanın semptom ve bulguları, akciğer tomografisinde bronşiektazi saptanması, düşük dışkı elastaz seviyeleri nedeni ile başlangıçta kistik fiboz tanısı düşünülmüştür. Ancak, hastanın enzim replasman tedavisine yanıtının düşük olması, ter testi sonuçlarının orta düzeyde olması ve gen analizinde kistik fibroz ilişkili mutasyonların saptanmaması nedeniyle ayırıcı tanılar için ileri incelemeler yapılmış ve hastaya Çölyak hastalığı tanısı konmuştur. Makalemizde, özellikle kistik fibroz tedavisine dirençli kistik fibroz bulguları olan hastaların Çölyak hastalığı açısından ileri incelenmesinin gerekliliği vurgulanmıştır. Diğer bir deyişle, Çölyak hastalığı, kesin kistik fibrozis tanısı konulamayan veya enzim replasman tedavisine dirençli kistik fibroz tanılı hastalarda ayırıcı tanıda düşünülmelidir.
Amac: Ozellikle hastanede yatarak tedavi goren cocuklarda olmak uzere, malnutrisyonun onemli bir... more Amac: Ozellikle hastanede yatarak tedavi goren cocuklarda olmak uzere, malnutrisyonun onemli bir mortalite nedeni oldugu iyi bilinmektedir. Tum dunyada malnutrisyonun tanimlanmasi acisindan bir karmasa soz konusu oldugundan, Dunya Saglik Orgutu (DSO) z-skorlamasinin kullanimini onermis ve DSO buyume standartlarinin tum ulkelerde gecerli olarak kullanilabilecegini bildirmistir. Bu calismanin amaci, hastanede yatarak tedavi gormekte olan cocuk hastalarda malnutrisyon durumunu degerlendirmek ve Neyzi buyume standartlari ile DSO standartlarini karsilastirmaktir. Hastalar ve Yontem: Bes yas altindaki hastalarda, ulusal Neyzi ve DSO 2006 standartlarina gore, yasa-gore-agirlik, boya-gore-agirlik ve yasa-gore-boy yuzdeleri ve z-skorlari hesaplandi, <-2 SD olan degerler malnutrisyon olarak tanimlandi. Bulgular: Calismaya alinan 100 hastanin 62’si erkek olup ortalama yas 15,9±16,2 ay idi. Akut malnutrisyon %12, kronik malnutrisyon %13 ve tarti azligi %11 olarak bulundu. Hesaplanan yasa-...
Introduction Children with tracheostomy have an increased risk of bacterial colonization and infe... more Introduction Children with tracheostomy have an increased risk of bacterial colonization and infections of the lower respiratory tracts. This study aimed to investigate the effects of nebulized antibiotics on the bacterial load, the need for oral antibiotic courses, the number of hospitalizations, and the length of stay in the intensive care unit in children with tracheostomy. Methods Children with tracheostomy and persistent bacterial colonization who were started on nebulized antibiotic therapy after a lower respiratory tract infection were included to the study. Nebulized gentamicin or colistin were used according to the results of tracheal aspirate cultures. Demographic and clinic characteristics were recorded from one year before until 12 months after initiating nebulized antibiotic treatment. Results Nebulized antibiotic treatment was initiated in 22 patients. Inhaled gentamicin was administered to 14 patients (63.6%) and colistin to 8 patients (36.4%). The median duration of ...
International journal of pediatric otorhinolaryngology, 2021
INTRODUCTION Children with tracheostomy have an increased risk of bacterial colonization and infe... more INTRODUCTION Children with tracheostomy have an increased risk of bacterial colonization and infection of the lower respiratory tracts. This study aimed to investigate the effects of nebulized antibiotics on the bacterial load, the need for oral antibiotics, the number of hospitalizations, and the length of stay in the intensive care unit in tracheotomised children with persistent colonization. METHODS Children with tracheostomy and persistent bacterial colonization who were started on nebulized antibiotic therapy after a lower respiratory tract infection were included in the study. Nebulized gentamicin or colistin were used according to the results of the tracheal aspirate cultures. Demographic and clinic characteristics were recorded from one year prior until one year after initiation of nebulized antibiotic treatment. RESULTS Nebulized antibiotic treatment was initiated in 22 patients. Nebulized gentamicin was administered to 14 patients (63.6%) and colistin to 8 patients (36.4%)...
Our aim was to assess impairment in quality of life (QOL) in asthmatic children and to determine ... more Our aim was to assess impairment in quality of life (QOL) in asthmatic children and to determine the influencing factors. The study group consisted of 305 outpatients with asthma, aged 7-17 years, who were undergoing regular checkups in our outpatient clinic. QOL was assessed using the Pediatric Asthma QOL Questionnaire (PAQLQ). Asthma severity, presence of allergic rhinitis, and steroid usage were strongly and negatively associated with the overall PAQLQ score (p = 0.038) in multivariate regression models. Sex, IgE levels, positive skin tests and smoking status demonstrated no statistically significant effects on the overall or three individual domain PAQLQ scores (p = 0.307, 0.137, 0.470, 0.353, respectively). Lung function measures were strongly correlated with each other (Spearman correlation of 0.77), but were not associated with QOL (p = 0.441). Fifty-one percent of the patients reported that asthma affected their lives significantly. This study captured the baseline QOL infor...
Objective: Zinc deficiency is prevalent in children in developing countries. Supplemental zinc pr... more Objective: Zinc deficiency is prevalent in children in developing countries. Supplemental zinc provides therapeutic benefits in diarrhea. Our aim was to evaluate the effect of daily zinc supplementation for 14 days on diarrhea duration, severity and morbidity in children. Methods: In a randomized, open label non-placebo controlled trial; we assessed the efficacy of providing zinc sulfate to 6 to 60 months old children with acute diarrhea for 2 weeks followed by 3 months of morbidity surveillance. Children were randomly assigned to zinc (n=150) and control (n=130) groups and received daily 15mg-30 mg elemental zinc. The trial outcomes included diarrheal duration, severity, incidence and prevalence. Results: Supplemented children had a significant improvement in plasma zinc levels by day 14 of therapy. Zinc deficiency was observed in 2.6 % of the treatment and 3.3 % of the control group. The mean duration of diarrhea after starting the supplement was 3.02 ± 2 days in the zinc group an...
Background: Pseudo-Bartter’s syndrome (PBS) is a clinical entity characterized by hypokalemia, hy... more Background: Pseudo-Bartter’s syndrome (PBS) is a clinical entity characterized by hypokalemia, hypochloremia associated with metabolic alkalosis. It is different from Bartter’s syndrome, in which hypokalemic metabolic alkalosis may develop without primary renal disease. Cystic fibrosis (CF), pyloric stenosis, continuous gastric drainage, cyclic vomiting, chloride loosing diarhea, and inappropriate laxative use can cause PBS. PBS can be an initial manifestation of CF or develops during follow-up of CF. Aim: In this study, we aimed to evaluate patients with CF with respect to the development of PBS during diagnosis and follow-up period. Methods: Patients with CF who were following up in our pediatric pulmonology and gastroenterology departments were evaluated with respect to PBS diagnosed at the beginning or during the course of the disease. Patients’ demographic characteristics, duration of hospitalization, and biochemical values were presented. Results: PBS was diagnosed in 7 (41.2%...
Background: Pseudo-Bartter’s syndrome (PBS) is a clinical entity characterized by hypokalemia, h... more Background: Pseudo-Bartter’s syndrome (PBS) is a clinical entity characterized by hypokalemia, hypochloremia associated with metabolic alkalosis. It is different from Bartter’s syndrome, in which hypokalemic metabolic alkalosis may develop without primary renal disease. Cystic fibrosis (CF), pyloric stenosis, continuous gastric drainage, cyclic vomiting, chloride loosing diarhea, and inappropriate laxative use can cause PBS. PBS can be an initial manifestation of CF or develops during follow-up of CF. Aim: In this study, we aimed to evaluate patients with CF with respect to the development of PBS during diagnosis and follow-up period. Methods: Patients with CF who were following up in our pediatric pulmonology and gastroenterology departments were evaluated with respect to PBS diagnosed at the beginning or during the course of the disease. Patients’ demographic characteristics, duration of hospitalization, and biochemical values were presented. Results: PBS was diagnosed in 7 (4...
Objective: The most frequent rheumatic diseases in children are Juvenie Rheumatoid Arthritis (JRA... more Objective: The most frequent rheumatic diseases in children are Juvenie Rheumatoid Arthritis (JRA) and Rheumatic Fever (RF) which still remain to be an important health problem in developing counties. Material and Methods: In our study, we aimed to assess clinical and laboratory finding of patients hospitalised for joint complaints and also to discuss RF and JRA with the enlighment of current literature. 39 patients thatwere hospitalised for arthritis and/or arthralgia, were retrospectively assesed in terms of age, sex, season of hospital admission,complaints at presentation, clinical and laboratory findings. Results: 38.6% were diagnosed as RF, 20.5% as JRA, 5.2% as septic arthritis, 7.69% as reactive arthritis, 5.2% as temporary synovitis and 2.56% were diagnosed as Behcet Disease andvasculitis. In ARF patients whom were diagnosed as having carditis clinically, % 87.5 had abnormal ECHO findings. In aUthe patients with no clinical carditis, ECHO results were normal Conclusion: JRA ...
Congenital pulmonary airway malformation (CPAM) is a rare developmental abnormality of the lung t... more Congenital pulmonary airway malformation (CPAM) is a rare developmental abnormality of the lung that has been associated with the presence of rhabdomyosarcoma, pleuropulmonary blastoma, and most commonly bronchioalveolar carcinoma of the lung. Here, we report the case of a 10-year-old boy complaining of only chest pain. Some authors advocate simple observation because of the lack of data on the incidence of long-term complications. However, there are very few described cases where CPAM have remained asymptomatic throughout life; complications eventually develop in virtually all patients. Most authors advocate elective resection of all CPAM because of the risk of complications, such as infection, hemorrhage, pneumothorax, and malignant transformation. Since resection will be required sooner or later for CPAM, it is best not to wait for complications to occur. In our opinion surgery can be delayed until the child is approximately 9 months old to allow for possible resolution without t...
Flexible bronchoscopy (FB) is frequently used for assessment and treatment of patients with respi... more Flexible bronchoscopy (FB) is frequently used for assessment and treatment of patients with respiratory diseases. Our aim was to investigate the contribution of FB to diagnosis and therapy in children admitted to the intensive care units (ICU) and to evaluate the safety of FB in this vulnerable population.
Certain occupational groups are known to be at particularly high risk of developing allergic dise... more Certain occupational groups are known to be at particularly high risk of developing allergic diseases. The objective of the present study was to evaluate the prevalence of allergic diseases among working adolescents. The International Study of Asthma and Allergies in Childhood questionnaire was used. Four hundred and thirty six adolescents working in motor, lathe-finish, coiffure and textile and 366 high school students as control group were enrolled to the study. Mean age was 16.8 +/- 1.2 years and 82.9% of them were male. There was no significant difference among groups for ever and current wheezing while doctor diagnosed asthma was higher in lathe- finish group (p = 0.036). Family history of allergy, history of allergic rhinitis, and active smoking were found to be risk factors for asthma and related symptoms. Working in coiffure (p = 0.054), and textile (p = 0.003) were significant risk factors for ever allergic rhinitis. Working in lathe finish (p = 0.023), coiffure (p = .002),...
Langerhans cell histiocytosis (LCH) is a rare disorder with diverse forms of clinical presentatio... more Langerhans cell histiocytosis (LCH) is a rare disorder with diverse forms of clinical presentation ranging from a benign course to diffuse progressive disease, and descriptions of LCH generally have been limited to single case reports and small case series. Since the condition is uncommon, we aimed in this study to describe our own experience and discuss the findings, treatment and outcome in our patients with LCH in light of the current literature. The eight patients (5 boys, 3 girls) ranged in age from 2 months to 3 years (mean 18 +/- 10.8 months). Multiple organ involvement was noted in 3, isolated bone involvement in 3, orbital involvement in 1, and pituitary gland involvement with rash in 1 patient. Treatment modalities used varied from simple observation to chemotherapy. Outcome results of our study demonstrated resolution of lesions in 5 patients and death in 2 patients. One patient with pituitary gland involvement developed diabetes insipidus and is receiving intranasal desm...
BACKGROUND Tracheostomy-related morbidity and mortality mainly occur due to decannulation, mispla... more BACKGROUND Tracheostomy-related morbidity and mortality mainly occur due to decannulation, misplacement or obstruction of the tube. A standardized training can improve the skills and confidence of the caregivers in tracheostomy care (TC). OBJECTIVE Our primary aim was to evaluate the efficiency of standardized training program on the knowledge and skills (changing-suctioning the tracheostomy tube) of the participants regarding TC. MATERIALS-METHODS Sixty-five caregivers of children with tracheostomy were included. First, participants were evaluated with written test about TC and participated in the practical tests. Then, they were asked to participate in a standardized training session, including theoretical and practical parts. Baseline and post-intervention assessments were compared through written and practical tests conducted on the same day. RESULTS A significant improvement was observed in the written test score after the training. The median number of correct answers of the written test including 23 questions increased 26%, from 12 to 18 (p<0.001). The median number of correct steps in tracheostomy tube change (from 9 to 16 correct steps out of 16 steps, 44% increase) and suctioning the tracheostomy tube (from 9 to 17 correct steps out of 18 steps, 44% increase) also improved significantly after the training (p<0.001, for both). CONCLUSION Theoretical courses and practical hands-on-training (HOT) courses are highly effective in improving the practices in TC. A standardized training program including HOT should be implemented before discharge from the hospital. Still there is a need to assess the impact of the program on tracheostomy-related complications, morbidity, and mortality in the long term. This article is protected by copyright. All rights reserved.
Çocukluk çağı astım tedavisinde lökotrien antagonisti ile inhale kortikosteroidler kullanılmaktad... more Çocukluk çağı astım tedavisinde lökotrien antagonisti ile inhale kortikosteroidler kullanılmaktadır. Çalışma, astım tanısı almış çocuklarda lökotrien reseptör antagonisti ile inhale kortikosteroid tedavisinin etkinliğini karşılaştırmak için yapılmıştır. Gereç ve Yöntem: Çalışmaya 6-14 yaş grubunda astım tanısı alan 62 hasta dâhil edildi. Hastalar ardışık iki gruba ayrılarak birinci gruba montelukast gece yatmadan önce 5 mg, ikinci gruba inhale kortikosteroid (budesonide) 400 mcg/gün 2 doza bölünerek verildi. Hastalar 6 ay süreyle takip edildi. Değerlendirmede FEV1'deki değişiklikler birincil hedef alındı. Ayrıca tedavi öncesi ve sonrası günlük kısa etkili β2 agonist kullanımı, gece uyanma, acile başvuru, okula devamsızlık değerleri ile karşılaştırıldı. Bulgular: Tedavi sonrasında, tedavi öncesine göre her iki grupta; FEV1 ortalamasında, kısa etkili β2 agonist kullanımı, gece uyanma, acile başvuru ve okula devamsızlık açısından ileri düzeyde düzelme görüldü (p=0,001). Ancak, iki grup arasında istatistiki fark saptanmadı. Sonuç: Astımlı çocuklarda tek başına monlelukast tedavisi; kolay uygulanabilir, güvenilir ve inhale kortikosteroidler kadar etkili bir seçenek olarak saptanmıştır.
Asian Pacific journal of allergy and immunology / launched by the Allergy and Immunology Society of Thailand
Certain occupational groups are known to be at particularly high risk of developing allergic dise... more Certain occupational groups are known to be at particularly high risk of developing allergic diseases. The objective of the present study was to evaluate the prevalence of allergic diseases among working adolescents. The International Study of Asthma and Allergies in Childhood questionnaire was used. Four hundred and thirty six adolescents working in motor, lathe-finish, coiffure and textile and 366 high school students as control group were enrolled to the study. Mean age was 16.8 +/- 1.2 years and 82.9% of them were male. There was no significant difference among groups for ever and current wheezing while doctor diagnosed asthma was higher in lathe- finish group (p = 0.036). Family history of allergy, history of allergic rhinitis, and active smoking were found to be risk factors for asthma and related symptoms. Working in coiffure (p = 0.054), and textile (p = 0.003) were significant risk factors for ever allergic rhinitis. Working in lathe finish (p = 0.023), coiffure (p = .002),...
Bu yazıda kronik ishal, tekrarlayan hışıltılı solunum atakları, sık solunum yolu enfeksiyonu, par... more Bu yazıda kronik ishal, tekrarlayan hışıltılı solunum atakları, sık solunum yolu enfeksiyonu, parmaklarda çomaklaşma ve büyüme geriliği bulunan 10 yaşında bir olgu sunulmuştur. Vakanın semptom ve bulguları, akciğer tomografisinde bronşiektazi saptanması, düşük dışkı elastaz seviyeleri nedeni ile başlangıçta kistik fiboz tanısı düşünülmüştür. Ancak, hastanın enzim replasman tedavisine yanıtının düşük olması, ter testi sonuçlarının orta düzeyde olması ve gen analizinde kistik fibroz ilişkili mutasyonların saptanmaması nedeniyle ayırıcı tanılar için ileri incelemeler yapılmış ve hastaya Çölyak hastalığı tanısı konmuştur. Makalemizde, özellikle kistik fibroz tedavisine dirençli kistik fibroz bulguları olan hastaların Çölyak hastalığı açısından ileri incelenmesinin gerekliliği vurgulanmıştır. Diğer bir deyişle, Çölyak hastalığı, kesin kistik fibrozis tanısı konulamayan veya enzim replasman tedavisine dirençli kistik fibroz tanılı hastalarda ayırıcı tanıda düşünülmelidir.
Amac: Ozellikle hastanede yatarak tedavi goren cocuklarda olmak uzere, malnutrisyonun onemli bir... more Amac: Ozellikle hastanede yatarak tedavi goren cocuklarda olmak uzere, malnutrisyonun onemli bir mortalite nedeni oldugu iyi bilinmektedir. Tum dunyada malnutrisyonun tanimlanmasi acisindan bir karmasa soz konusu oldugundan, Dunya Saglik Orgutu (DSO) z-skorlamasinin kullanimini onermis ve DSO buyume standartlarinin tum ulkelerde gecerli olarak kullanilabilecegini bildirmistir. Bu calismanin amaci, hastanede yatarak tedavi gormekte olan cocuk hastalarda malnutrisyon durumunu degerlendirmek ve Neyzi buyume standartlari ile DSO standartlarini karsilastirmaktir. Hastalar ve Yontem: Bes yas altindaki hastalarda, ulusal Neyzi ve DSO 2006 standartlarina gore, yasa-gore-agirlik, boya-gore-agirlik ve yasa-gore-boy yuzdeleri ve z-skorlari hesaplandi, <-2 SD olan degerler malnutrisyon olarak tanimlandi. Bulgular: Calismaya alinan 100 hastanin 62’si erkek olup ortalama yas 15,9±16,2 ay idi. Akut malnutrisyon %12, kronik malnutrisyon %13 ve tarti azligi %11 olarak bulundu. Hesaplanan yasa-...
Introduction Children with tracheostomy have an increased risk of bacterial colonization and infe... more Introduction Children with tracheostomy have an increased risk of bacterial colonization and infections of the lower respiratory tracts. This study aimed to investigate the effects of nebulized antibiotics on the bacterial load, the need for oral antibiotic courses, the number of hospitalizations, and the length of stay in the intensive care unit in children with tracheostomy. Methods Children with tracheostomy and persistent bacterial colonization who were started on nebulized antibiotic therapy after a lower respiratory tract infection were included to the study. Nebulized gentamicin or colistin were used according to the results of tracheal aspirate cultures. Demographic and clinic characteristics were recorded from one year before until 12 months after initiating nebulized antibiotic treatment. Results Nebulized antibiotic treatment was initiated in 22 patients. Inhaled gentamicin was administered to 14 patients (63.6%) and colistin to 8 patients (36.4%). The median duration of ...
International journal of pediatric otorhinolaryngology, 2021
INTRODUCTION Children with tracheostomy have an increased risk of bacterial colonization and infe... more INTRODUCTION Children with tracheostomy have an increased risk of bacterial colonization and infection of the lower respiratory tracts. This study aimed to investigate the effects of nebulized antibiotics on the bacterial load, the need for oral antibiotics, the number of hospitalizations, and the length of stay in the intensive care unit in tracheotomised children with persistent colonization. METHODS Children with tracheostomy and persistent bacterial colonization who were started on nebulized antibiotic therapy after a lower respiratory tract infection were included in the study. Nebulized gentamicin or colistin were used according to the results of the tracheal aspirate cultures. Demographic and clinic characteristics were recorded from one year prior until one year after initiation of nebulized antibiotic treatment. RESULTS Nebulized antibiotic treatment was initiated in 22 patients. Nebulized gentamicin was administered to 14 patients (63.6%) and colistin to 8 patients (36.4%)...
Our aim was to assess impairment in quality of life (QOL) in asthmatic children and to determine ... more Our aim was to assess impairment in quality of life (QOL) in asthmatic children and to determine the influencing factors. The study group consisted of 305 outpatients with asthma, aged 7-17 years, who were undergoing regular checkups in our outpatient clinic. QOL was assessed using the Pediatric Asthma QOL Questionnaire (PAQLQ). Asthma severity, presence of allergic rhinitis, and steroid usage were strongly and negatively associated with the overall PAQLQ score (p = 0.038) in multivariate regression models. Sex, IgE levels, positive skin tests and smoking status demonstrated no statistically significant effects on the overall or three individual domain PAQLQ scores (p = 0.307, 0.137, 0.470, 0.353, respectively). Lung function measures were strongly correlated with each other (Spearman correlation of 0.77), but were not associated with QOL (p = 0.441). Fifty-one percent of the patients reported that asthma affected their lives significantly. This study captured the baseline QOL infor...
Objective: Zinc deficiency is prevalent in children in developing countries. Supplemental zinc pr... more Objective: Zinc deficiency is prevalent in children in developing countries. Supplemental zinc provides therapeutic benefits in diarrhea. Our aim was to evaluate the effect of daily zinc supplementation for 14 days on diarrhea duration, severity and morbidity in children. Methods: In a randomized, open label non-placebo controlled trial; we assessed the efficacy of providing zinc sulfate to 6 to 60 months old children with acute diarrhea for 2 weeks followed by 3 months of morbidity surveillance. Children were randomly assigned to zinc (n=150) and control (n=130) groups and received daily 15mg-30 mg elemental zinc. The trial outcomes included diarrheal duration, severity, incidence and prevalence. Results: Supplemented children had a significant improvement in plasma zinc levels by day 14 of therapy. Zinc deficiency was observed in 2.6 % of the treatment and 3.3 % of the control group. The mean duration of diarrhea after starting the supplement was 3.02 ± 2 days in the zinc group an...
Background: Pseudo-Bartter’s syndrome (PBS) is a clinical entity characterized by hypokalemia, hy... more Background: Pseudo-Bartter’s syndrome (PBS) is a clinical entity characterized by hypokalemia, hypochloremia associated with metabolic alkalosis. It is different from Bartter’s syndrome, in which hypokalemic metabolic alkalosis may develop without primary renal disease. Cystic fibrosis (CF), pyloric stenosis, continuous gastric drainage, cyclic vomiting, chloride loosing diarhea, and inappropriate laxative use can cause PBS. PBS can be an initial manifestation of CF or develops during follow-up of CF. Aim: In this study, we aimed to evaluate patients with CF with respect to the development of PBS during diagnosis and follow-up period. Methods: Patients with CF who were following up in our pediatric pulmonology and gastroenterology departments were evaluated with respect to PBS diagnosed at the beginning or during the course of the disease. Patients’ demographic characteristics, duration of hospitalization, and biochemical values were presented. Results: PBS was diagnosed in 7 (41.2%...
Background: Pseudo-Bartter’s syndrome (PBS) is a clinical entity characterized by hypokalemia, h... more Background: Pseudo-Bartter’s syndrome (PBS) is a clinical entity characterized by hypokalemia, hypochloremia associated with metabolic alkalosis. It is different from Bartter’s syndrome, in which hypokalemic metabolic alkalosis may develop without primary renal disease. Cystic fibrosis (CF), pyloric stenosis, continuous gastric drainage, cyclic vomiting, chloride loosing diarhea, and inappropriate laxative use can cause PBS. PBS can be an initial manifestation of CF or develops during follow-up of CF. Aim: In this study, we aimed to evaluate patients with CF with respect to the development of PBS during diagnosis and follow-up period. Methods: Patients with CF who were following up in our pediatric pulmonology and gastroenterology departments were evaluated with respect to PBS diagnosed at the beginning or during the course of the disease. Patients’ demographic characteristics, duration of hospitalization, and biochemical values were presented. Results: PBS was diagnosed in 7 (4...
Objective: The most frequent rheumatic diseases in children are Juvenie Rheumatoid Arthritis (JRA... more Objective: The most frequent rheumatic diseases in children are Juvenie Rheumatoid Arthritis (JRA) and Rheumatic Fever (RF) which still remain to be an important health problem in developing counties. Material and Methods: In our study, we aimed to assess clinical and laboratory finding of patients hospitalised for joint complaints and also to discuss RF and JRA with the enlighment of current literature. 39 patients thatwere hospitalised for arthritis and/or arthralgia, were retrospectively assesed in terms of age, sex, season of hospital admission,complaints at presentation, clinical and laboratory findings. Results: 38.6% were diagnosed as RF, 20.5% as JRA, 5.2% as septic arthritis, 7.69% as reactive arthritis, 5.2% as temporary synovitis and 2.56% were diagnosed as Behcet Disease andvasculitis. In ARF patients whom were diagnosed as having carditis clinically, % 87.5 had abnormal ECHO findings. In aUthe patients with no clinical carditis, ECHO results were normal Conclusion: JRA ...
Congenital pulmonary airway malformation (CPAM) is a rare developmental abnormality of the lung t... more Congenital pulmonary airway malformation (CPAM) is a rare developmental abnormality of the lung that has been associated with the presence of rhabdomyosarcoma, pleuropulmonary blastoma, and most commonly bronchioalveolar carcinoma of the lung. Here, we report the case of a 10-year-old boy complaining of only chest pain. Some authors advocate simple observation because of the lack of data on the incidence of long-term complications. However, there are very few described cases where CPAM have remained asymptomatic throughout life; complications eventually develop in virtually all patients. Most authors advocate elective resection of all CPAM because of the risk of complications, such as infection, hemorrhage, pneumothorax, and malignant transformation. Since resection will be required sooner or later for CPAM, it is best not to wait for complications to occur. In our opinion surgery can be delayed until the child is approximately 9 months old to allow for possible resolution without t...
Flexible bronchoscopy (FB) is frequently used for assessment and treatment of patients with respi... more Flexible bronchoscopy (FB) is frequently used for assessment and treatment of patients with respiratory diseases. Our aim was to investigate the contribution of FB to diagnosis and therapy in children admitted to the intensive care units (ICU) and to evaluate the safety of FB in this vulnerable population.
Certain occupational groups are known to be at particularly high risk of developing allergic dise... more Certain occupational groups are known to be at particularly high risk of developing allergic diseases. The objective of the present study was to evaluate the prevalence of allergic diseases among working adolescents. The International Study of Asthma and Allergies in Childhood questionnaire was used. Four hundred and thirty six adolescents working in motor, lathe-finish, coiffure and textile and 366 high school students as control group were enrolled to the study. Mean age was 16.8 +/- 1.2 years and 82.9% of them were male. There was no significant difference among groups for ever and current wheezing while doctor diagnosed asthma was higher in lathe- finish group (p = 0.036). Family history of allergy, history of allergic rhinitis, and active smoking were found to be risk factors for asthma and related symptoms. Working in coiffure (p = 0.054), and textile (p = 0.003) were significant risk factors for ever allergic rhinitis. Working in lathe finish (p = 0.023), coiffure (p = .002),...
Langerhans cell histiocytosis (LCH) is a rare disorder with diverse forms of clinical presentatio... more Langerhans cell histiocytosis (LCH) is a rare disorder with diverse forms of clinical presentation ranging from a benign course to diffuse progressive disease, and descriptions of LCH generally have been limited to single case reports and small case series. Since the condition is uncommon, we aimed in this study to describe our own experience and discuss the findings, treatment and outcome in our patients with LCH in light of the current literature. The eight patients (5 boys, 3 girls) ranged in age from 2 months to 3 years (mean 18 +/- 10.8 months). Multiple organ involvement was noted in 3, isolated bone involvement in 3, orbital involvement in 1, and pituitary gland involvement with rash in 1 patient. Treatment modalities used varied from simple observation to chemotherapy. Outcome results of our study demonstrated resolution of lesions in 5 patients and death in 2 patients. One patient with pituitary gland involvement developed diabetes insipidus and is receiving intranasal desm...
BACKGROUND Tracheostomy-related morbidity and mortality mainly occur due to decannulation, mispla... more BACKGROUND Tracheostomy-related morbidity and mortality mainly occur due to decannulation, misplacement or obstruction of the tube. A standardized training can improve the skills and confidence of the caregivers in tracheostomy care (TC). OBJECTIVE Our primary aim was to evaluate the efficiency of standardized training program on the knowledge and skills (changing-suctioning the tracheostomy tube) of the participants regarding TC. MATERIALS-METHODS Sixty-five caregivers of children with tracheostomy were included. First, participants were evaluated with written test about TC and participated in the practical tests. Then, they were asked to participate in a standardized training session, including theoretical and practical parts. Baseline and post-intervention assessments were compared through written and practical tests conducted on the same day. RESULTS A significant improvement was observed in the written test score after the training. The median number of correct answers of the written test including 23 questions increased 26%, from 12 to 18 (p<0.001). The median number of correct steps in tracheostomy tube change (from 9 to 16 correct steps out of 16 steps, 44% increase) and suctioning the tracheostomy tube (from 9 to 17 correct steps out of 18 steps, 44% increase) also improved significantly after the training (p<0.001, for both). CONCLUSION Theoretical courses and practical hands-on-training (HOT) courses are highly effective in improving the practices in TC. A standardized training program including HOT should be implemented before discharge from the hospital. Still there is a need to assess the impact of the program on tracheostomy-related complications, morbidity, and mortality in the long term. This article is protected by copyright. All rights reserved.
Çocukluk çağı astım tedavisinde lökotrien antagonisti ile inhale kortikosteroidler kullanılmaktad... more Çocukluk çağı astım tedavisinde lökotrien antagonisti ile inhale kortikosteroidler kullanılmaktadır. Çalışma, astım tanısı almış çocuklarda lökotrien reseptör antagonisti ile inhale kortikosteroid tedavisinin etkinliğini karşılaştırmak için yapılmıştır. Gereç ve Yöntem: Çalışmaya 6-14 yaş grubunda astım tanısı alan 62 hasta dâhil edildi. Hastalar ardışık iki gruba ayrılarak birinci gruba montelukast gece yatmadan önce 5 mg, ikinci gruba inhale kortikosteroid (budesonide) 400 mcg/gün 2 doza bölünerek verildi. Hastalar 6 ay süreyle takip edildi. Değerlendirmede FEV1'deki değişiklikler birincil hedef alındı. Ayrıca tedavi öncesi ve sonrası günlük kısa etkili β2 agonist kullanımı, gece uyanma, acile başvuru, okula devamsızlık değerleri ile karşılaştırıldı. Bulgular: Tedavi sonrasında, tedavi öncesine göre her iki grupta; FEV1 ortalamasında, kısa etkili β2 agonist kullanımı, gece uyanma, acile başvuru ve okula devamsızlık açısından ileri düzeyde düzelme görüldü (p=0,001). Ancak, iki grup arasında istatistiki fark saptanmadı. Sonuç: Astımlı çocuklarda tek başına monlelukast tedavisi; kolay uygulanabilir, güvenilir ve inhale kortikosteroidler kadar etkili bir seçenek olarak saptanmıştır.
Uploads
Papers by Sedat Oktem