Acute liver failure due to concomitant arterial, portal and biliary injury during laparoscopic ch... more Acute liver failure due to concomitant arterial, portal and biliary injury during laparoscopic cholecystectomy: is transplantation a valid life-saving strategy? A case report
Toxic hepatitis by consumption Herbalife® products is an affection poorly documented and with a g... more Toxic hepatitis by consumption Herbalife® products is an affection poorly documented and with a great impact in the population due to their massive consumption. We present the case of a 63 years old woman with probable diagnosis of toxic hepatitis secondary to the consumption of nutritional supplements Herbalife®. The nutritional supplements based on natural ingredients are of massive consumption worldwide. Because they are recognized like innocuous and of noncontrolled comercialization, they lack suitable controls. Although there are reported cases of hepatotoxicity and other side effects induced by these products, there is still not strong evidence to generate a positive reaction of the control organisms. We report a case of acute toxic hepatitis potencially due to the consumption of Herbalife®.
Toxic hepatitis by consumption Herbalife products is an affection poorly documented and with a gr... more Toxic hepatitis by consumption Herbalife products is an affection poorly documented and with a great impact in the population due to their massive consumption. We present the case of a 63-years-old woman with probable diagnosis of toxic hepatitis secondary to the consumption of nutritional supplements Herbalife. The nutritional supplements based on natural ingredients are of massive consumption worldwide. Because they are recognized like innocuous and of non-controlled comercialization, they lack suitable controls. Although there are reported cases of hepatotoxicity and other side effects induced by these products, there is still not strong evidence to generate a positive reaction of the control organisms. We report a case of acute toxic hepatitis potencially due to the consumption of Herbalife.
Background: Combined iatrogenic vascular and biliary injury during cholecystectomy resulting in i... more Background: Combined iatrogenic vascular and biliary injury during cholecystectomy resulting in ischemic hepatic necrosis is a very rare cause of acute liver failure. We describe a patient who developed fulminant liver failure as a result of severe cholestasis and liver gangrene secondary to iatrogenic combine injury or the hepatic pedicle (i.e. hepatic artery, portal vein and bile duct) during laparoscopic cholecystectomy. Case presentation: A 40-years-old woman underwent laparoscopic cholecystectomy for acute cholecystitis. During laparoscopy, a severe bleeding at the liver hilum motivated the conversion to open surgery. Many sutures were placed across the parenchyma for bleeding control. After 48 hours, she rapidly deteriorated with encephalopathy, coagulopathy, persistent hypotension and progressive organ dysfunction including acute renal failure requiring hemodialysis and mechanical ventilation. An angiography documented an occlusion of right hepatic artery and right portal vein. In the clinical of acute liver failure secondary to liver gangrene, severe coagulopathy and progressive secondary multi-organ failure, the patient was included in the waiting list for liver transplantation. Two days later, the patient was successfully transplanted with initial adequate liver graft function. However, she developed bilateral pneumonia and severe gastrointestinal bleeding and finally died 24 days after transplantation due to bilateral necrotizing pneumonia. Conclusion: The occurrence of acute liver failure due to portal triad injury during laparoscopic cholecystectomy is a catastrophic complication. Probably, the indication of liver transplantation as a life-saving strategy in patients with late diagnosis, acute liver failure, severe coagulopathy and progressive secondary multi-organ failure could be considered but only minimizing immunosuppressive regimen to avoid postoperative infections.
Background: Combined iatrogenic vascular and biliary injury during cholecystectomy resulting in i... more Background: Combined iatrogenic vascular and biliary injury during cholecystectomy resulting in ischemic hepatic necrosis is a very rare cause of acute liver failure. We describe a patient who developed fulminant liver failure as a result of severe cholestasis and liver gangrene secondary to iatrogenic combine injury or the hepatic pedicle (i.e. hepatic artery, portal vein and bile duct) during laparoscopic cholecystectomy.
Toxic hepatitis by consumption Herbalife® products is an affection poorly documented and with a g... more Toxic hepatitis by consumption Herbalife® products is an affection poorly documented and with a great impact in the population due to their massive consumption. We present the case of a 63 years old woman with probable diagnosis of toxic hepatitis secondary to the consumption of nutritional supplements Herbalife®. The nutritional supplements based on natural ingredients are of massive consumption worldwide. Because they are recognized like innocuous and of noncontrolled comercialization, they lack suitable controls. Although there are reported cases of hepatotoxicity and other side effects induced by these products, there is still not strong evidence to generate a positive reaction of the control organisms. We report a case of acute toxic hepatitis potencially due to the consumption of Herbalife®.
Background: Combined iatrogenic vascular and biliary injury during cholecystectomy resulting in i... more Background: Combined iatrogenic vascular and biliary injury during cholecystectomy resulting in ischemic hepatic necrosis is a very rare cause of acute liver failure. We describe a patient who developed fulminant liver failure as a result of severe cholestasis and liver gangrene secondary to iatrogenic combine injury or the hepatic pedicle (i.e. hepatic artery, portal vein and bile duct) during laparoscopic cholecystectomy.
La hepatitis tóxica por el consumo de productos Herbalife ® es una afección poco documentada y co... more La hepatitis tóxica por el consumo de productos Herbalife ® es una afección poco documentada y con gran impacto en la población debido a su amplio consumo. Presentamos el caso de una mujer de 63 años con diagnóstico probable de hepatitis tóxica secundaria al consumo de suplementos dietarios Herbalife ® . Los suplementos dietarios basados en ingredientes naturales son de consumo masivo en todo el mundo. Debido a que son reconocidos como inocuos y de venta libre, carecen de controles adecuados. Existen casos reportados de hepatotoxicidad y otros efectos adversos inducidos por estos productos, pero la evidencia no es suficiente como para generar una respuesta de los organismos de control. Nosotros reportamos un caso de hepatitis aguda potencialmente secundaria al consumo de Herbalife ® .
Acute liver failure due to concomitant arterial, portal and biliary injury during laparoscopic ch... more Acute liver failure due to concomitant arterial, portal and biliary injury during laparoscopic cholecystectomy: is transplantation a valid life-saving strategy? A case report
Toxic hepatitis by consumption Herbalife® products is an affection poorly documented and with a g... more Toxic hepatitis by consumption Herbalife® products is an affection poorly documented and with a great impact in the population due to their massive consumption. We present the case of a 63 years old woman with probable diagnosis of toxic hepatitis secondary to the consumption of nutritional supplements Herbalife®. The nutritional supplements based on natural ingredients are of massive consumption worldwide. Because they are recognized like innocuous and of noncontrolled comercialization, they lack suitable controls. Although there are reported cases of hepatotoxicity and other side effects induced by these products, there is still not strong evidence to generate a positive reaction of the control organisms. We report a case of acute toxic hepatitis potencially due to the consumption of Herbalife®.
Toxic hepatitis by consumption Herbalife products is an affection poorly documented and with a gr... more Toxic hepatitis by consumption Herbalife products is an affection poorly documented and with a great impact in the population due to their massive consumption. We present the case of a 63-years-old woman with probable diagnosis of toxic hepatitis secondary to the consumption of nutritional supplements Herbalife. The nutritional supplements based on natural ingredients are of massive consumption worldwide. Because they are recognized like innocuous and of non-controlled comercialization, they lack suitable controls. Although there are reported cases of hepatotoxicity and other side effects induced by these products, there is still not strong evidence to generate a positive reaction of the control organisms. We report a case of acute toxic hepatitis potencially due to the consumption of Herbalife.
Background: Combined iatrogenic vascular and biliary injury during cholecystectomy resulting in i... more Background: Combined iatrogenic vascular and biliary injury during cholecystectomy resulting in ischemic hepatic necrosis is a very rare cause of acute liver failure. We describe a patient who developed fulminant liver failure as a result of severe cholestasis and liver gangrene secondary to iatrogenic combine injury or the hepatic pedicle (i.e. hepatic artery, portal vein and bile duct) during laparoscopic cholecystectomy. Case presentation: A 40-years-old woman underwent laparoscopic cholecystectomy for acute cholecystitis. During laparoscopy, a severe bleeding at the liver hilum motivated the conversion to open surgery. Many sutures were placed across the parenchyma for bleeding control. After 48 hours, she rapidly deteriorated with encephalopathy, coagulopathy, persistent hypotension and progressive organ dysfunction including acute renal failure requiring hemodialysis and mechanical ventilation. An angiography documented an occlusion of right hepatic artery and right portal vein. In the clinical of acute liver failure secondary to liver gangrene, severe coagulopathy and progressive secondary multi-organ failure, the patient was included in the waiting list for liver transplantation. Two days later, the patient was successfully transplanted with initial adequate liver graft function. However, she developed bilateral pneumonia and severe gastrointestinal bleeding and finally died 24 days after transplantation due to bilateral necrotizing pneumonia. Conclusion: The occurrence of acute liver failure due to portal triad injury during laparoscopic cholecystectomy is a catastrophic complication. Probably, the indication of liver transplantation as a life-saving strategy in patients with late diagnosis, acute liver failure, severe coagulopathy and progressive secondary multi-organ failure could be considered but only minimizing immunosuppressive regimen to avoid postoperative infections.
Background: Combined iatrogenic vascular and biliary injury during cholecystectomy resulting in i... more Background: Combined iatrogenic vascular and biliary injury during cholecystectomy resulting in ischemic hepatic necrosis is a very rare cause of acute liver failure. We describe a patient who developed fulminant liver failure as a result of severe cholestasis and liver gangrene secondary to iatrogenic combine injury or the hepatic pedicle (i.e. hepatic artery, portal vein and bile duct) during laparoscopic cholecystectomy.
Toxic hepatitis by consumption Herbalife® products is an affection poorly documented and with a g... more Toxic hepatitis by consumption Herbalife® products is an affection poorly documented and with a great impact in the population due to their massive consumption. We present the case of a 63 years old woman with probable diagnosis of toxic hepatitis secondary to the consumption of nutritional supplements Herbalife®. The nutritional supplements based on natural ingredients are of massive consumption worldwide. Because they are recognized like innocuous and of noncontrolled comercialization, they lack suitable controls. Although there are reported cases of hepatotoxicity and other side effects induced by these products, there is still not strong evidence to generate a positive reaction of the control organisms. We report a case of acute toxic hepatitis potencially due to the consumption of Herbalife®.
Background: Combined iatrogenic vascular and biliary injury during cholecystectomy resulting in i... more Background: Combined iatrogenic vascular and biliary injury during cholecystectomy resulting in ischemic hepatic necrosis is a very rare cause of acute liver failure. We describe a patient who developed fulminant liver failure as a result of severe cholestasis and liver gangrene secondary to iatrogenic combine injury or the hepatic pedicle (i.e. hepatic artery, portal vein and bile duct) during laparoscopic cholecystectomy.
La hepatitis tóxica por el consumo de productos Herbalife ® es una afección poco documentada y co... more La hepatitis tóxica por el consumo de productos Herbalife ® es una afección poco documentada y con gran impacto en la población debido a su amplio consumo. Presentamos el caso de una mujer de 63 años con diagnóstico probable de hepatitis tóxica secundaria al consumo de suplementos dietarios Herbalife ® . Los suplementos dietarios basados en ingredientes naturales son de consumo masivo en todo el mundo. Debido a que son reconocidos como inocuos y de venta libre, carecen de controles adecuados. Existen casos reportados de hepatotoxicidad y otros efectos adversos inducidos por estos productos, pero la evidencia no es suficiente como para generar una respuesta de los organismos de control. Nosotros reportamos un caso de hepatitis aguda potencialmente secundaria al consumo de Herbalife ® .
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