Papers by Robert Barishak
Episcleral traumatic conjunctival inclusion cyst
British Journal of Ophthalmology, 1977
A hugh episcleral traumatic conjunctival inclusion cyst enveloping almost the whole eye, which ap... more A hugh episcleral traumatic conjunctival inclusion cyst enveloping almost the whole eye, which appeared in the left phthisical eye of a young woman who sustained a perforating ocular injury a few years before enucleation, is described.
Obstruction of Lacrimal Puncta Caused by Topical Epinephrine
Ophthalmologica, 1973
Neurofibromatosis and Congenital Glaucoma
Ophthalmologica, 1978
Obstruction of Lacrimal Sac Caused by Topical Epinephrine
Ophthalmologica, 1969
Iridoschisis and Angle-Closure Glaucoma
Ophthalmologica, 1972
The Diagnosis of Retinoblastomas
Ophthalmologica, 1966
Recurrent Traumatic Hyphema Due to Increased Local Fibrinolysis
Ophthalmologica, 1980
A 20-year-old male was injured in his right eye by the stopper of a bottle filled with carbonated... more A 20-year-old male was injured in his right eye by the stopper of a bottle filled with carbonated fruit juice. The contusion caused a recurrent hyphema which lasted approximately 6 weeks and responded to epsilon-aminocaproic acid treatment. Among the investigations for coagulation and fibrinolysis, the only pathological laboratory finding was a shortened plasma euglobulin clot lysis time (1.5 h) which returned to normal (4--5 h) following the epsilon-aminocaproic and treatment.
Retinal Folding in Chicks Enhanced by Vitamin E Deficiency and Dietary Polyunsaturated Fatty Acids
Ophthalmologica, 1983
Retinal folding appeared in young chicks fed a commercial starter diet. The degree of this foldin... more Retinal folding appeared in young chicks fed a commercial starter diet. The degree of this folding was increased when diets deficient in vitamin E and enriched with polyunsaturated fatty acids (encephalomalatic diets) were fed. The unique response of the retina and the cerebellum to the encephalomalatic diets is pointed out.
Documenta Ophthalmologica, 1982
The tear fluid contains proteins which are synthesized locally in the conjuncfiva and lacrimal gl... more The tear fluid contains proteins which are synthesized locally in the conjuncfiva and lacrimal glands, and others, which reach the tear fluid from the blood circulation. It is generally accepted that serum albumin (HSA) belongs to the latter group of tear proteins. Consequently, the ratio between tile levels of HSA in the tear fluid and in the blood serum can be used as a parameter for the degree of vascular leakage. All blood-borue tear proteins will show concentration ratios in tears and blood serum similar to HSA, provided that they pass through the blood-tear barrier at the same flow rate as HSA. This principle may be used to determine whether a certain tear protein is blood-borne or locally synthesized. An additional method to determine the source of tear proteins is supposed, and is based on the assumption that blood-borne proteins will occur in tears from both eyes at a concentration ratio similar to that of HSA, whereas the concentration ratios of locally synthesized proteins will not be related to the HSA-levels in the tears of the two eyes. This method is independent of the rate of diffusion through tissue barriers.
Incipient Histopathological Lesions in Citral-Induced Microphthalmos in Chick Embryos
Developmental Neuroscience, 1978
Microphthalmos was indeed experimentally in 3-day-old chick embryos by intraamniotic injection of... more Microphthalmos was indeed experimentally in 3-day-old chick embryos by intraamniotic injection of citral. Various degrees of this particular microphthalmic syndrome were observed. Severe cases were always accompanied by destructive changes in the ipsilateral part of the head. The corneal epithelium lost its continuity and the lens showed, even in the early stages, severe degenerative changes with spherophakia. The neural retina seemed to be affected later and showed hyperplasia and fold formation, while the retinal pigment epithelium was only mildly affected. The mesenchyme behaved differently according to its location: the superficial corneal and ciliary mesenchyme underwent hyperplasia, while the deeper choroidal mesoderm showed edematous changes only. This temporal and spatial distribution of pathological changes in the eye structures favors the assumption that citral acts locally. The experimental microphthalmic syndrome is not only due to the direct effect of the exogenous teratogenic factor on the ocular anlagen but is also the result of subsequent adaptive changes of these structures to the new environmental condition.
Acta Ophthalmologica, 2009
A 40-year-old woman, blind in her right eye since childhood and in the left since the age of 15, ... more A 40-year-old woman, blind in her right eye since childhood and in the left since the age of 15, presented a gliomatous tumoral mass filling up the eyes completely. Sections of the optic nerve of one eye showed the same cellular aspect noted in both intraocular tumors. The optic foramina had a normal size and there were no signs of Recklinghausen's disease. The diagnosis was bilateral reactive gliosis but the presence of a congenital anomaly has to be postulated in order to explain the involvement of the optic nerve in the process of intraocular gliosis.
Veterinary Ophthalmology, 2007
In recent years there have been significant advances in our knowledge and understanding of the ge... more In recent years there have been significant advances in our knowledge and understanding of the genetic control of embryonic development. The aim of this paper is to review the current state of knowledge regarding genetic control of embryogenesis, the first stage of ocular development. Products of numerous genes participate in signaling, induction and control during the formation of the neural plate, groove and tube, key events leading to the development of the future eye.
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Papers by Robert Barishak