Viraemia and faecal shedding of HEV in symptom-free carriers
The Lancet, 2001
Rakesh Aggarwal and colleagues (Sept 23, p 1081) 1 report that hepatitis E virus (HEV) RNA is not... more Rakesh Aggarwal and colleagues (Sept 23, p 1081) 1 report that hepatitis E virus (HEV) RNA is not detected in stool or serum samples beyond the phase of clinical course and biochemical hepatitis. They conclude that recovered patients are unlikely to serve as ...
European Journal of Clinical Microbiology & Infectious Diseases, 1991
The specificity of three HIV EIAs using synthetic peptides was evaluated and compared with that o... more The specificity of three HIV EIAs using synthetic peptides was evaluated and compared with that of four commercial EIAs using recombinant proteins or whole virus lysates of HIV-1 or of HIV-1 and HIV-2, and of two tests based on agglutination of sensitized particles. A total of 734 West African sera were screened. The best results were obtained with tests using recombinant proteins. HIV tests using synthetic peptides able to distinguish between HIV-1 and HIV-2 antibodies showed comparable specificity, but some false negative results represent a major handicap of these peptide EIAs in screening for HIV antibodies.
[Difficulties of the patients to undergo their ARV treatment at the Libreville outpatient health center, Gabon]
Bulletin de la Societe de pathologie exotique, 2006
The therapeutic observance is a real issue of chronic diseases. This issue is twice as much impor... more The therapeutic observance is a real issue of chronic diseases. This issue is twice as much important in the case of aids treatment by antiretrovirals as a good observance is essential to avoid emergence of resistances and to improve patients' health. A research was conducted in Libreville, the capital of Gabon, at the ambulatory treatment center of HIV patients. The interviews of one hundred patients of the center, under treatment for more than two months, concerned their problems related to specific drugs intake and have helped to point out some reasons of non observance. The first reason refers to side effects inducing many difficulties in regular drugs intakes, a complete information is requested by the patients. Another main reason of non observance or bad observance is linked to material and financial problems or to treatment's reduced accessibility The research points out the importance of supplementary treatment costs (transportation, sick leave, food). At last, majo...
Aspects of HIV risks and ritual practices in tropical Africa
Certains rites africains tels que l’excision et la circoncision, les scarifications et la fratern... more Certains rites africains tels que l’excision et la circoncision, les scarifications et la fraternite de sang, ont ete impliques dans le risque de transmission du VIH le plus souvent par voie sanguine lorsque ces pratiques utilisent des instruments non steriles. Cependant la circoncision pourrait intervenir a deux niveaux : il semble que l’homme non circoncis ait un risque augmente de contamination sexuelle par le VIH ; d’autre part le danger existe par voie sanguine lors des circoncisions en serie a differents âges selon les ethnies. L’excision est couramment pratiquee parmi les ethnies vivant entre le Tropique du Cancer et le 4e Parallele Nord : il peut s’agir de clitoridectomie simple, d’excision proprement dite ou d’infibulation. Les scarifications, principalement au niveau de la face, sont realisees lors des ceremonies secretes de l’initiation. Les pratiques medicales traditionnelles (incisions, scarifications) peuvent presenter un risque. En attendant des etudes sero-epidemiolo...
Rhésus positif = 94,7 %, * Institut National de Santé Publique-BP V 47-Abidjan. ** Adresse actuel... more Rhésus positif = 94,7 %, * Institut National de Santé Publique-BP V 47-Abidjan. ** Adresse actuelle Centre Orstom-BP 5045-F 34032-Montpellier 3-RESULTATS 3.1-Répartition selon les grands groupes ethniques Au cours de l'année 1985, 11 229 groupages sanguins ont été réalisés. La répartition par groupe AB O et Rhésus est la suivante :
Les auteurs décrivent I50 cas de méningites purulentes chez des enfants hospitalisés à l'hôpital ... more Les auteurs décrivent I50 cas de méningites purulentes chez des enfants hospitalisés à l'hôpital protestant de Dabou (56 km d'Abidjan). Les étiologies sont dominées par hémophilus et pneumocoque. Le taux de létalité varie de 22 % à 78 % selon I'âge et de 22,4 % à 47,2 % selon le germe en cause. Le taux de séquelles est évalué à 25 %.
Viraemia and faecal shedding of HEV in symptom-free carriers
The Lancet, 2001
Rakesh Aggarwal and colleagues (Sept 23, p 1081) 1 report that hepatitis E virus (HEV) RNA is not... more Rakesh Aggarwal and colleagues (Sept 23, p 1081) 1 report that hepatitis E virus (HEV) RNA is not detected in stool or serum samples beyond the phase of clinical course and biochemical hepatitis. They conclude that recovered patients are unlikely to serve as ...
European Journal of Clinical Microbiology & Infectious Diseases, 1991
The specificity of three HIV EIAs using synthetic peptides was evaluated and compared with that o... more The specificity of three HIV EIAs using synthetic peptides was evaluated and compared with that of four commercial EIAs using recombinant proteins or whole virus lysates of HIV-1 or of HIV-1 and HIV-2, and of two tests based on agglutination of sensitized particles. A total of 734 West African sera were screened. The best results were obtained with tests using recombinant proteins. HIV tests using synthetic peptides able to distinguish between HIV-1 and HIV-2 antibodies showed comparable specificity, but some false negative results represent a major handicap of these peptide EIAs in screening for HIV antibodies.
[Difficulties of the patients to undergo their ARV treatment at the Libreville outpatient health center, Gabon]
Bulletin de la Societe de pathologie exotique, 2006
The therapeutic observance is a real issue of chronic diseases. This issue is twice as much impor... more The therapeutic observance is a real issue of chronic diseases. This issue is twice as much important in the case of aids treatment by antiretrovirals as a good observance is essential to avoid emergence of resistances and to improve patients' health. A research was conducted in Libreville, the capital of Gabon, at the ambulatory treatment center of HIV patients. The interviews of one hundred patients of the center, under treatment for more than two months, concerned their problems related to specific drugs intake and have helped to point out some reasons of non observance. The first reason refers to side effects inducing many difficulties in regular drugs intakes, a complete information is requested by the patients. Another main reason of non observance or bad observance is linked to material and financial problems or to treatment's reduced accessibility The research points out the importance of supplementary treatment costs (transportation, sick leave, food). At last, majo...
Aspects of HIV risks and ritual practices in tropical Africa
Certains rites africains tels que l’excision et la circoncision, les scarifications et la fratern... more Certains rites africains tels que l’excision et la circoncision, les scarifications et la fraternite de sang, ont ete impliques dans le risque de transmission du VIH le plus souvent par voie sanguine lorsque ces pratiques utilisent des instruments non steriles. Cependant la circoncision pourrait intervenir a deux niveaux : il semble que l’homme non circoncis ait un risque augmente de contamination sexuelle par le VIH ; d’autre part le danger existe par voie sanguine lors des circoncisions en serie a differents âges selon les ethnies. L’excision est couramment pratiquee parmi les ethnies vivant entre le Tropique du Cancer et le 4e Parallele Nord : il peut s’agir de clitoridectomie simple, d’excision proprement dite ou d’infibulation. Les scarifications, principalement au niveau de la face, sont realisees lors des ceremonies secretes de l’initiation. Les pratiques medicales traditionnelles (incisions, scarifications) peuvent presenter un risque. En attendant des etudes sero-epidemiolo...
Rhésus positif = 94,7 %, * Institut National de Santé Publique-BP V 47-Abidjan. ** Adresse actuel... more Rhésus positif = 94,7 %, * Institut National de Santé Publique-BP V 47-Abidjan. ** Adresse actuelle Centre Orstom-BP 5045-F 34032-Montpellier 3-RESULTATS 3.1-Répartition selon les grands groupes ethniques Au cours de l'année 1985, 11 229 groupages sanguins ont été réalisés. La répartition par groupe AB O et Rhésus est la suivante :
Les auteurs décrivent I50 cas de méningites purulentes chez des enfants hospitalisés à l'hôpital ... more Les auteurs décrivent I50 cas de méningites purulentes chez des enfants hospitalisés à l'hôpital protestant de Dabou (56 km d'Abidjan). Les étiologies sont dominées par hémophilus et pneumocoque. Le taux de létalité varie de 22 % à 78 % selon I'âge et de 22,4 % à 47,2 % selon le germe en cause. Le taux de séquelles est évalué à 25 %.
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