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Ramyash Yadav

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Papers by Ramyash Yadav

A comparative study for the management of nasolacrimal duct obstruction; transcanalicular laser DCR vs conventional external DCR

IP international journal of ocular oncology and oculoplasty, Feb 15, 2021

Purpose: To evaluate the incidence and severity of intra operative and Postoperative complication... more Purpose: To evaluate the incidence and severity of intra operative and Postoperative complication and success rate of transcanalicular laser DCR and compare it with conventional external DCR. Method: This is a prospective randomized interventional comparative clinical study. In which 163 patients having complain of epiphora due to nasolacrimal duct obstruction were included. 168 operations were done out of which 79 patients underwent TLDCR and 84 patients underwent External DCR (Ext DCR) surgery. Patient between the ages of 15 to 65 yrs were included. Patient were evaluated postoperatively after one week, two week, one month, two month, six monthly and one yearly. Postoperatively patients were evaluated for improvement of symptoms and patency of nasolacrimal duct system by irrigation with syringing. Success were defined as patent lacrimal passage. Result: TLDCR and Ext DCR both treatment modalities are equally good for management of nasolacrimal duct obstruction. But Intraoperative and postoperative complications are less with TLDCR as compared to Ext DCR. Conclusion: In this prospective clinical trial TLDCR was minimally invasive surgical technique with less complication rate as compared to Ext DCR but result were same in both the procedures.

A Study of profile of glaucoma in eastern UP

Indian Journal of Clinical and Experimental Ophthalmology, 2016

Objective: To study the profile of glaucoma patients in Eastern UP. Method: Prospective cross sec... more Objective: To study the profile of glaucoma patients in Eastern UP. Method: Prospective cross sectional study includes 193 cases of age group (more than 30 years). Both male and female were included. Results: The total number of 193 cases was studied. Out of these 106 (54.9%) were male and 87 (45.07%) were female with a male female ratio was 1.21. Primary glaucoma was more common than secondary glaucoma. Among primary glaucoma, primary narrow angle glaucoma (44.4%) was more common followed by primary open angle glaucoma (36.2%). Mean age of POAG patients was (54.2±7.2 years), PNAG was (60.1±11.1 years), NTG was of (64.6±11.8 years), ocular hypertension was of (55±7.2 years) and secondary glaucoma was of (53.2±11.2 years). PNAG was more common in females and rest of glaucoma was common in male. Glaucoma, Profile, Visual impairment, Eastern U.P. Conclusion: Glaucoma causes progressive atrophy of the optic disc resulting in typical defects in the visual field. It can lead to total loss of vision if left untreated. The diagnosis glaucoma has to be made only after comprehensive eye examination and not only on one parameter. Regular follow up is must to access progression which is essential for glaucoma. Glaucoma awareness has to be created among peoples, for them to get examined at early stage to rule out presence of glaucoma. If glaucoma is found, appropriate management is provided to prevent visual function impairment or loss.

Effectiveness of intrastromal voriconazole injection in the management of deep non healing fungal corneal ulcer

Indian Journal of Clinical and Experimental Ophthalmology, Oct 15, 2022

One of the most difficult conditions to cure is often corneal fungus infections. Due to low strom... more One of the most difficult conditions to cure is often corneal fungus infections. Due to low stromal penetration, current topical antifungal medications are not very successful in the treatment of fungal keratitis, which makes it challenging to treat cases of deep fungal corneal ulcers. Aims and Objective: To assess the efficiency of voriconazole intra stromal injection in the treatment of deep fungal corneal ulcers that donot heal. Materials and Methods: In this prospective interventional study of thirty patients, deep non-healing fungal corneal ulcers were successfully treated by combining intrastromal voriconazole with topical therapy. Voriconazole 50 gm/0.1 ml was injected intrastromally into the corneas of 30 patients with deep stromal non-healing fungal corneal ulcers who had not responded to topical antifungal medication. Results: Patients were monitored for six to ten weeks following the operation. The size of the corneal infiltration was noted to decrease more quickly, and in the majority of cases, ulcers completely disappeared between 6 to 10 weeks. Conclusion: As an additional therapy, intrastromal voriconazole injection may be a safe and efficient strategy to treat cases of deeply seated fungal corneal ulcers that refuse to heal. This is an Open Access (OA) journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.

Effectiveness of intrastromal voriconazole injection in the management of deep non healing fungal corneal ulcer

Indian Journal of Clinical and Experimental Ophthalmology

One of the most difficult conditions to cure is often corneal fungus infections. Due to low strom... more One of the most difficult conditions to cure is often corneal fungus infections. Due to low stromal penetration, current topical antifungal medications are not very successful in the treatment of fungal keratitis, which makes it challenging to treat cases of deep fungal corneal ulcers. To assess the efficiency of voriconazole intra stromal injection in the treatment of deep fungal corneal ulcers that donot heal. In this prospective interventional study of thirty patients, deep non-healing fungal corneal ulcers were successfully treated by combining intrastromal voriconazole with topical therapy. Voriconazole 50 gm/0.1 ml was injected intrastromally into the corneas of 30 patients with deep stromal non-healing fungal corneal ulcers who had not responded to topical antifungal medication. Patients were monitored for six to ten weeks following the operation. The size of the corneal infiltration was noted to decrease more quickly, and in the majority of cases, ulcers completely disappear...

Myopia, Primary Open Angle Glaucoma, Intraocular Pressure, Central Corneal Thickness, Trabecular Iris Angle

Clinical Profile of Myopic Patients as a Risk Factor for Primary Open Angle Glaucoma - A Prospective Observational Study in Gorakhpur, Uttar Pradesh, Aug 16, 2021

Best Corrected Visual Acuity, Diabetic Macular Oedema, Foveal and Para-Foveal Thickness, Intravitreal Ranibizumab, Intravitreal Triamcinolone Acetonide

Efficacy and Safety of Intravitreal Injection Ranibizumab versus Triamcinolone Acetonide in Diabetic Macular Oedema - A Prospective Randomized Study, Gorakhpur, Uttar Pradesh, May 7, 2021

A comparative study for the management of nasolacrimal duct obstruction; transcanalicular laser DCR vs conventional external DCR

Purpose: To evaluate the incidence and severity of intra operative and Postoperative complication... more Purpose: To evaluate the incidence and severity of intra operative and Postoperative complication and success rate of transcanalicular laser DCR and compare it with conventional external DCR. Method: This is a prospective randomized interventional comparative clinical study. In which 163 patients having complain of epiphora due to nasolacrimal duct obstruction were included. 168 operations were done out of which 79 patients underwent TLDCR and 84 patients underwent External DCR (Ext DCR) surgery. Patient between the ages of 15 to 65 yrs were included. Patient were evaluated postoperatively after one week, two week, one month, two month, six monthly and one yearly. Postoperatively patients were evaluated for improvement of symptoms and patency of nasolacrimal duct system by irrigation with syringing. Success were defined as patent lacrimal passage. Result: TLDCR and Ext DCR both treatment modalities are equally good for management of nasolacrimal duct obstruction. But Intraoperative ...

Efficacy and Safety of Intravitreal Injection Ranibizumab versus Triamcinolone Acetonide in Diabetic Macular Oedema - A Prospective Randomized Study, Gorakhpur, Uttar Pradesh

Journal of Evidence Based Medicine and Healthcare, 2021

BACKGROUND Diabetic macular oedema is a sight threatening complication of diabetic retinopathy. V... more BACKGROUND Diabetic macular oedema is a sight threatening complication of diabetic retinopathy. Vascular endothelial growth factor (VEGF) plays an important role in developing diabetic macular oedema. There are many treatment options available for diabetic macular oedema such as laser therapy, intravitreal injectable medications like anti-VEGF and steroids. This study intends to compare the efficacy and safety of intravitreal injection Ranibizumab (anti-VEGF) and Triamcinolone acetonide (steroid) in diabetic macular oedema. METHODS This is a prospective randomized study conducted among 42 patients ≥ 18 years of age with diabetic macular oedema presenting to outpatient department in a tertiary care centre in Gorakhpur, UP, conducted from November 2019 – December 2020. 42 participating patients were divided into 2 groups, A and B with 21 patients in each group. Group A treated with intravitreal injection Ranibizumab (0.05 ml ; 0.50 mg) and group B treated with intravitreal injection T...

Clinical Profile of Myopic Patients as a Risk Factor for Primary Open Angle Glaucoma - A Prospective Observational Study in Gorakhpur, Uttar Pradesh

Journal of Evidence Based Medicine and Healthcare, 2021

BACKGROUND Myopia is a complex trait including both genetic and environmental factors as well as ... more BACKGROUND Myopia is a complex trait including both genetic and environmental factors as well as gene-environment interactions. It has been recognized as a risk factor for development of glaucoma. Both Myopia and raised IOP are known to increase mechanical stress at optic nerve head leading to glaucomatous nerve damage. This study intends to evaluate the clinical profile of myopic subjects and its correlation with Primary open angle glaucoma (POAG). METHODS A prospective observational study done from November 2019 to December 2020 after taking proper informed consent and ethical clearance. 164 eyes of 96 patients studied were divided into three groups, Group 1: low myopia (< -3.00D), Group 2: moderate myopia (-3.00 D to -5.75 D), Group 3: high myopia (≥ -6.00 D). A complete ocular examination was performed. Intraocular pressure was measured using Goldmann applanation tonometer. Visual field analysis using Humphrey automated perimetry was done in patients with suspected primary op...

Ocular Findings in Encephalitis Patients: A Clinical Study

Ophthalmology and Allied Sciences, 2017

A Study of profile of glaucoma in eastern UP

Indian Journal of Clinical and Experimental Ophthalmology, 2016

Objective: To study the profile of glaucoma patients in Eastern UP. Method: Prospective cross sec... more Objective: To study the profile of glaucoma patients in Eastern UP. Method: Prospective cross sectional study includes 193 cases of age group (more than 30 years). Both male and female were included. Results: The total number of 193 cases was studied. Out of these 106 (54.9%) were male and 87 (45.07%) were female with a male female ratio was 1.21. Primary glaucoma was more common than secondary glaucoma. Among primary glaucoma, primary narrow angle glaucoma (44.4%) was more common followed by primary open angle glaucoma (36.2%). Mean age of POAG patients was (54.2±7.2 years), PNAG was (60.1±11.1 years), NTG was of (64.6±11.8 years), ocular hypertension was of (55±7.2 years) and secondary glaucoma was of (53.2±11.2 years). PNAG was more common in females and rest of glaucoma was common in male. Glaucoma, Profile, Visual impairment, Eastern U.P. Conclusion: Glaucoma causes progressive atrophy of the optic disc resulting in typical defects in the visual field. It can lead to total loss of vision if left untreated. The diagnosis glaucoma has to be made only after comprehensive eye examination and not only on one parameter. Regular follow up is must to access progression which is essential for glaucoma. Glaucoma awareness has to be created among peoples, for them to get examined at early stage to rule out presence of glaucoma. If glaucoma is found, appropriate management is provided to prevent visual function impairment or loss.

Factors influencing healing of fungal keratitis under treatment: A clinical study

Indian Journal of Clinical and Experimental Ophthalmology, 2016

To study the local and general factors influencing healing of fungal keratitis. To evaluate the e... more To study the local and general factors influencing healing of fungal keratitis. To evaluate the effects of various antimycotic treatment regimens of fungal keratitis. Method: The patients were taken up from those attending the outpatient department of ophthalmology of Nehru hospital attached to B.R.D Medical College Gorakhpur from June 2006 to October 2007. All cases of corneal ulcer with clinical features of fungal keratitis and cases of corneal ulcer with positive 10% potassium hydroxide mount 1,2 were selected, detailed history taken and examination done under (a) general examination, (b) systemic examination and detailed ocular examination along with blood investigations and 10% potassium hydroxide mount 1,2 preparation. Treatment evaluation and follow up was done regularly for the period of one month, progression and treatment response noted and parameters were recorded .the ulcer was taken: Healed: If the epithelial defect had healed with negative fluorescein staining and there was no progressive stromal infiltration. Delayed healing: If the size of ulcer decreased but not fully healed and still require further active treatment and Failed: If the size of ulcer remained same or increased or ulcer got perforated requiring active surgical intervention. Result: 47 pts were included in study, 5 patients did not turn up. 18 patients (42.86%) leave the study with successful healing of corneal ulcer, 9 patients (21.43%) required further treatment due to delayed healing response and treatment failure occurred in 15 patients(35.71%) requiring active surgical treatment in form of conjunctival hooding, Amniotic membrane graft, evisceration etc. Conclusion: From the observation of this study it can be concluded that fungal keratitis is a suppurative, ulcerative disease of cornea, with a poor visual outcome even with the best efforts due to inability of highly sensitive and specific tools. Disease is more common in patients with reduced immunity, trauma with vegetative matter, low socioeconomic status and injudicious use of steroids. There is also big lack of specific and effective fungicidal drugs. All available anti-fungal drugs are very slow acting and prevent the growth of fungus only, without killing it. At present the most effective drug is topical 5% Natamycin, which is also fungi-static and slow acting.

Variability of IOP following laser photocoagulation used in the treatment of diabetic retinopathy

International Surgery Journal, 2017

Background: Diabetic retinopathy (DR) is the leading cause of blindness in most industrialized co... more Background: Diabetic retinopathy (DR) is the leading cause of blindness in most industrialized countries. This study was undertaken to assess the variability of IOP following laser photocoagulation used in the treatment of diabetic retinopathy.Methods: This study was conducted at Department of Opthalmology, B.R.D. Medical College, Gorakhpur from June 2015 to December 2016. This study was intended to see the onset and duration of intraocular pressure spikes in diabetic retinopathy patients after green laser photocoagulation (532 nm) (Nidek). Forty patients were followed for next 3 months. The data was analysed by using SPSS version 15.0. Chi-square test and T test was used.Results: Out of 40 patients, 2 (5%) had background Diabetic retinopathy (DR) with maculopathy, 10 (25%) having pre-proliferative DR, 28 (70%) having proliferative DR. Out of 2 BDR patients, 1 (50%) developed immediate post laser angle closure (Schaffer's grade 1) which persisted for 3 days and another had shown...

A comparative study for the management of nasolacrimal duct obstruction; transcanalicular laser DCR vs conventional external DCR

IP international journal of ocular oncology and oculoplasty, Feb 15, 2021

Purpose: To evaluate the incidence and severity of intra operative and Postoperative complication... more Purpose: To evaluate the incidence and severity of intra operative and Postoperative complication and success rate of transcanalicular laser DCR and compare it with conventional external DCR. Method: This is a prospective randomized interventional comparative clinical study. In which 163 patients having complain of epiphora due to nasolacrimal duct obstruction were included. 168 operations were done out of which 79 patients underwent TLDCR and 84 patients underwent External DCR (Ext DCR) surgery. Patient between the ages of 15 to 65 yrs were included. Patient were evaluated postoperatively after one week, two week, one month, two month, six monthly and one yearly. Postoperatively patients were evaluated for improvement of symptoms and patency of nasolacrimal duct system by irrigation with syringing. Success were defined as patent lacrimal passage. Result: TLDCR and Ext DCR both treatment modalities are equally good for management of nasolacrimal duct obstruction. But Intraoperative and postoperative complications are less with TLDCR as compared to Ext DCR. Conclusion: In this prospective clinical trial TLDCR was minimally invasive surgical technique with less complication rate as compared to Ext DCR but result were same in both the procedures.

A Study of profile of glaucoma in eastern UP

Indian Journal of Clinical and Experimental Ophthalmology, 2016

Objective: To study the profile of glaucoma patients in Eastern UP. Method: Prospective cross sec... more Objective: To study the profile of glaucoma patients in Eastern UP. Method: Prospective cross sectional study includes 193 cases of age group (more than 30 years). Both male and female were included. Results: The total number of 193 cases was studied. Out of these 106 (54.9%) were male and 87 (45.07%) were female with a male female ratio was 1.21. Primary glaucoma was more common than secondary glaucoma. Among primary glaucoma, primary narrow angle glaucoma (44.4%) was more common followed by primary open angle glaucoma (36.2%). Mean age of POAG patients was (54.2±7.2 years), PNAG was (60.1±11.1 years), NTG was of (64.6±11.8 years), ocular hypertension was of (55±7.2 years) and secondary glaucoma was of (53.2±11.2 years). PNAG was more common in females and rest of glaucoma was common in male. Glaucoma, Profile, Visual impairment, Eastern U.P. Conclusion: Glaucoma causes progressive atrophy of the optic disc resulting in typical defects in the visual field. It can lead to total loss of vision if left untreated. The diagnosis glaucoma has to be made only after comprehensive eye examination and not only on one parameter. Regular follow up is must to access progression which is essential for glaucoma. Glaucoma awareness has to be created among peoples, for them to get examined at early stage to rule out presence of glaucoma. If glaucoma is found, appropriate management is provided to prevent visual function impairment or loss.

Effectiveness of intrastromal voriconazole injection in the management of deep non healing fungal corneal ulcer

Indian Journal of Clinical and Experimental Ophthalmology, Oct 15, 2022

One of the most difficult conditions to cure is often corneal fungus infections. Due to low strom... more One of the most difficult conditions to cure is often corneal fungus infections. Due to low stromal penetration, current topical antifungal medications are not very successful in the treatment of fungal keratitis, which makes it challenging to treat cases of deep fungal corneal ulcers. Aims and Objective: To assess the efficiency of voriconazole intra stromal injection in the treatment of deep fungal corneal ulcers that donot heal. Materials and Methods: In this prospective interventional study of thirty patients, deep non-healing fungal corneal ulcers were successfully treated by combining intrastromal voriconazole with topical therapy. Voriconazole 50 gm/0.1 ml was injected intrastromally into the corneas of 30 patients with deep stromal non-healing fungal corneal ulcers who had not responded to topical antifungal medication. Results: Patients were monitored for six to ten weeks following the operation. The size of the corneal infiltration was noted to decrease more quickly, and in the majority of cases, ulcers completely disappeared between 6 to 10 weeks. Conclusion: As an additional therapy, intrastromal voriconazole injection may be a safe and efficient strategy to treat cases of deeply seated fungal corneal ulcers that refuse to heal. This is an Open Access (OA) journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.

Effectiveness of intrastromal voriconazole injection in the management of deep non healing fungal corneal ulcer

Indian Journal of Clinical and Experimental Ophthalmology

One of the most difficult conditions to cure is often corneal fungus infections. Due to low strom... more One of the most difficult conditions to cure is often corneal fungus infections. Due to low stromal penetration, current topical antifungal medications are not very successful in the treatment of fungal keratitis, which makes it challenging to treat cases of deep fungal corneal ulcers. To assess the efficiency of voriconazole intra stromal injection in the treatment of deep fungal corneal ulcers that donot heal. In this prospective interventional study of thirty patients, deep non-healing fungal corneal ulcers were successfully treated by combining intrastromal voriconazole with topical therapy. Voriconazole 50 gm/0.1 ml was injected intrastromally into the corneas of 30 patients with deep stromal non-healing fungal corneal ulcers who had not responded to topical antifungal medication. Patients were monitored for six to ten weeks following the operation. The size of the corneal infiltration was noted to decrease more quickly, and in the majority of cases, ulcers completely disappear...

Myopia, Primary Open Angle Glaucoma, Intraocular Pressure, Central Corneal Thickness, Trabecular Iris Angle

Clinical Profile of Myopic Patients as a Risk Factor for Primary Open Angle Glaucoma - A Prospective Observational Study in Gorakhpur, Uttar Pradesh, Aug 16, 2021

Best Corrected Visual Acuity, Diabetic Macular Oedema, Foveal and Para-Foveal Thickness, Intravitreal Ranibizumab, Intravitreal Triamcinolone Acetonide

Efficacy and Safety of Intravitreal Injection Ranibizumab versus Triamcinolone Acetonide in Diabetic Macular Oedema - A Prospective Randomized Study, Gorakhpur, Uttar Pradesh, May 7, 2021

A comparative study for the management of nasolacrimal duct obstruction; transcanalicular laser DCR vs conventional external DCR

Purpose: To evaluate the incidence and severity of intra operative and Postoperative complication... more Purpose: To evaluate the incidence and severity of intra operative and Postoperative complication and success rate of transcanalicular laser DCR and compare it with conventional external DCR. Method: This is a prospective randomized interventional comparative clinical study. In which 163 patients having complain of epiphora due to nasolacrimal duct obstruction were included. 168 operations were done out of which 79 patients underwent TLDCR and 84 patients underwent External DCR (Ext DCR) surgery. Patient between the ages of 15 to 65 yrs were included. Patient were evaluated postoperatively after one week, two week, one month, two month, six monthly and one yearly. Postoperatively patients were evaluated for improvement of symptoms and patency of nasolacrimal duct system by irrigation with syringing. Success were defined as patent lacrimal passage. Result: TLDCR and Ext DCR both treatment modalities are equally good for management of nasolacrimal duct obstruction. But Intraoperative ...

Efficacy and Safety of Intravitreal Injection Ranibizumab versus Triamcinolone Acetonide in Diabetic Macular Oedema - A Prospective Randomized Study, Gorakhpur, Uttar Pradesh

Journal of Evidence Based Medicine and Healthcare, 2021

BACKGROUND Diabetic macular oedema is a sight threatening complication of diabetic retinopathy. V... more BACKGROUND Diabetic macular oedema is a sight threatening complication of diabetic retinopathy. Vascular endothelial growth factor (VEGF) plays an important role in developing diabetic macular oedema. There are many treatment options available for diabetic macular oedema such as laser therapy, intravitreal injectable medications like anti-VEGF and steroids. This study intends to compare the efficacy and safety of intravitreal injection Ranibizumab (anti-VEGF) and Triamcinolone acetonide (steroid) in diabetic macular oedema. METHODS This is a prospective randomized study conducted among 42 patients ≥ 18 years of age with diabetic macular oedema presenting to outpatient department in a tertiary care centre in Gorakhpur, UP, conducted from November 2019 – December 2020. 42 participating patients were divided into 2 groups, A and B with 21 patients in each group. Group A treated with intravitreal injection Ranibizumab (0.05 ml ; 0.50 mg) and group B treated with intravitreal injection T...

Clinical Profile of Myopic Patients as a Risk Factor for Primary Open Angle Glaucoma - A Prospective Observational Study in Gorakhpur, Uttar Pradesh

Journal of Evidence Based Medicine and Healthcare, 2021

BACKGROUND Myopia is a complex trait including both genetic and environmental factors as well as ... more BACKGROUND Myopia is a complex trait including both genetic and environmental factors as well as gene-environment interactions. It has been recognized as a risk factor for development of glaucoma. Both Myopia and raised IOP are known to increase mechanical stress at optic nerve head leading to glaucomatous nerve damage. This study intends to evaluate the clinical profile of myopic subjects and its correlation with Primary open angle glaucoma (POAG). METHODS A prospective observational study done from November 2019 to December 2020 after taking proper informed consent and ethical clearance. 164 eyes of 96 patients studied were divided into three groups, Group 1: low myopia (< -3.00D), Group 2: moderate myopia (-3.00 D to -5.75 D), Group 3: high myopia (≥ -6.00 D). A complete ocular examination was performed. Intraocular pressure was measured using Goldmann applanation tonometer. Visual field analysis using Humphrey automated perimetry was done in patients with suspected primary op...

Ocular Findings in Encephalitis Patients: A Clinical Study

Ophthalmology and Allied Sciences, 2017

A Study of profile of glaucoma in eastern UP

Indian Journal of Clinical and Experimental Ophthalmology, 2016

Objective: To study the profile of glaucoma patients in Eastern UP. Method: Prospective cross sec... more Objective: To study the profile of glaucoma patients in Eastern UP. Method: Prospective cross sectional study includes 193 cases of age group (more than 30 years). Both male and female were included. Results: The total number of 193 cases was studied. Out of these 106 (54.9%) were male and 87 (45.07%) were female with a male female ratio was 1.21. Primary glaucoma was more common than secondary glaucoma. Among primary glaucoma, primary narrow angle glaucoma (44.4%) was more common followed by primary open angle glaucoma (36.2%). Mean age of POAG patients was (54.2±7.2 years), PNAG was (60.1±11.1 years), NTG was of (64.6±11.8 years), ocular hypertension was of (55±7.2 years) and secondary glaucoma was of (53.2±11.2 years). PNAG was more common in females and rest of glaucoma was common in male. Glaucoma, Profile, Visual impairment, Eastern U.P. Conclusion: Glaucoma causes progressive atrophy of the optic disc resulting in typical defects in the visual field. It can lead to total loss of vision if left untreated. The diagnosis glaucoma has to be made only after comprehensive eye examination and not only on one parameter. Regular follow up is must to access progression which is essential for glaucoma. Glaucoma awareness has to be created among peoples, for them to get examined at early stage to rule out presence of glaucoma. If glaucoma is found, appropriate management is provided to prevent visual function impairment or loss.

Factors influencing healing of fungal keratitis under treatment: A clinical study

Indian Journal of Clinical and Experimental Ophthalmology, 2016

To study the local and general factors influencing healing of fungal keratitis. To evaluate the e... more To study the local and general factors influencing healing of fungal keratitis. To evaluate the effects of various antimycotic treatment regimens of fungal keratitis. Method: The patients were taken up from those attending the outpatient department of ophthalmology of Nehru hospital attached to B.R.D Medical College Gorakhpur from June 2006 to October 2007. All cases of corneal ulcer with clinical features of fungal keratitis and cases of corneal ulcer with positive 10% potassium hydroxide mount 1,2 were selected, detailed history taken and examination done under (a) general examination, (b) systemic examination and detailed ocular examination along with blood investigations and 10% potassium hydroxide mount 1,2 preparation. Treatment evaluation and follow up was done regularly for the period of one month, progression and treatment response noted and parameters were recorded .the ulcer was taken: Healed: If the epithelial defect had healed with negative fluorescein staining and there was no progressive stromal infiltration. Delayed healing: If the size of ulcer decreased but not fully healed and still require further active treatment and Failed: If the size of ulcer remained same or increased or ulcer got perforated requiring active surgical intervention. Result: 47 pts were included in study, 5 patients did not turn up. 18 patients (42.86%) leave the study with successful healing of corneal ulcer, 9 patients (21.43%) required further treatment due to delayed healing response and treatment failure occurred in 15 patients(35.71%) requiring active surgical treatment in form of conjunctival hooding, Amniotic membrane graft, evisceration etc. Conclusion: From the observation of this study it can be concluded that fungal keratitis is a suppurative, ulcerative disease of cornea, with a poor visual outcome even with the best efforts due to inability of highly sensitive and specific tools. Disease is more common in patients with reduced immunity, trauma with vegetative matter, low socioeconomic status and injudicious use of steroids. There is also big lack of specific and effective fungicidal drugs. All available anti-fungal drugs are very slow acting and prevent the growth of fungus only, without killing it. At present the most effective drug is topical 5% Natamycin, which is also fungi-static and slow acting.

Variability of IOP following laser photocoagulation used in the treatment of diabetic retinopathy

International Surgery Journal, 2017

Background: Diabetic retinopathy (DR) is the leading cause of blindness in most industrialized co... more Background: Diabetic retinopathy (DR) is the leading cause of blindness in most industrialized countries. This study was undertaken to assess the variability of IOP following laser photocoagulation used in the treatment of diabetic retinopathy.Methods: This study was conducted at Department of Opthalmology, B.R.D. Medical College, Gorakhpur from June 2015 to December 2016. This study was intended to see the onset and duration of intraocular pressure spikes in diabetic retinopathy patients after green laser photocoagulation (532 nm) (Nidek). Forty patients were followed for next 3 months. The data was analysed by using SPSS version 15.0. Chi-square test and T test was used.Results: Out of 40 patients, 2 (5%) had background Diabetic retinopathy (DR) with maculopathy, 10 (25%) having pre-proliferative DR, 28 (70%) having proliferative DR. Out of 2 BDR patients, 1 (50%) developed immediate post laser angle closure (Schaffer's grade 1) which persisted for 3 days and another had shown...