Papers by Rajashekar Reddy
Asian Journal of Pharmaceutical and Clinical Research, 2018
Objective: This current study was carried out to determine the in vitro α-amylase and α-glucosida... more Objective: This current study was carried out to determine the in vitro α-amylase and α-glucosidase inhibitory activity of extract and fractions of Albizia procera. Methods: The α-amylase and α-glucosidase inhibition assay was carried out at concentrations 50–2000 μg/ml and acarbose used as standard. The absorbance was measured at 540 nm and recorded by spectrophotometer. Percentage inhibition was calculated for both the assays. Preliminary phytochemical screening was also evaluated using standard procedures.Results: There was a dose-dependent percentage inhibition of extracts (petroleum ether and ethanol) and fractions (chloroform, ethyl acetate, and n-butanol). The ethanol extract and n-butanol fraction show good inhibitory activity against both α-amylase and α-glucosidase with the percentage inhibition of 86.20% and 88.20% and 83.13% and 87.10%, respectively. The preliminary phytochemical screening shows that ethanol extract consists of active constituents such as flavonoids and ...
Bearing Capacity of Inclined Reinforced Sand Bed on Clay
Lecture notes in civil engineering, 2020
Reinforcement is arranged (placed) usually horizontal underneath the footings, to restrain develo... more Reinforcement is arranged (placed) usually horizontal underneath the footings, to restrain developed tensile strains in soil, which in turn increases the reinforced sand bed shearing resistance by means of interfacial bond resistance and limited by tensile strength of its own. Present work analyzes geosynthetic reinforced foundation bed with reinforcement placed inclined downward from center toward edges at an inclination varying from 0 to 10° and evaluated the normalized bearing capacity values. Sand bed reinforced with inclined reinforcement overlying clay is studied by computing enhancement in normalized bearing capacity against reinforced foundation bed with reinforcement placed horizontally. The variation of normalized bearing capacity with angle of shearing resistance of sand bed, length of reinforcement, interface angle of shearing resistance, and intensity of surcharge is studied. This paper quantifies the increase in bearing capacity of sand bed reinforced with inclined reinforcement over the conventional method of placing reinforcement horizontally.
Background: Health problems associated with ageing are multiple and sparse data are available on ... more Background: Health problems associated with ageing are multiple and sparse data are available on this topic from India. Methods: We carried out an observational study in 200 of geriatric patients (age 60 years) at our medical college teaching hospital at Kuppam, Andhra Pradesh during the period November 2012 and October 2013. Results: Most patients (31%) were in age group 65-69 years. The most common disease conditions noted were hypertension (49%), diabetes mellitus (47%), and chronic obstructive pulmonary disease (37%). Majority of the patients (82.5%) had more than one co-morbid condition. Conclusions: Cardiovascular and respiratory diseases are important causes for hospital admission in geriatric patients. The majority of cases had three or more diagnoses necessitating admission contributing to higher disease burden in the elderly.
Learning and analytics in intelligent systems, Jul 27, 2019
The paper presents a method for the estimation of bearing capacity of a strip footing resting on ... more The paper presents a method for the estimation of bearing capacity of a strip footing resting on a reinforced foundation bed over soft ground stabilized with a granular trench. Meyerhof's two-layered punching failure mechanism along with Madhav and Vitkar's solution for bearing capacity of granular trench supported footing resting on soft ground, form the basis of the analysis. The bearing capacity of a strip footing in a two-layered system of reinforced granular fill overlying soft ground stabilized with granular trench is estimated by incorporating the contribution from the axial tension mobilized in the reinforcement to those from the granular fill and the stabilized soft ground. A parametric study quantifies the effect of various parameters on the degree of bearing capacity improvement. The predictions are compared with experimental studies available in literature. The percentage improvement in the bearing capacity of the strip footing due to reinforcement of the soft ground with a granular trench coupled with unreinforced and reinforced granular fill is established through the comparisons. Keywords Bearing capacity Á Soft ground Á Granular trench Á Granular fill Á Geosynthetic reinforcement Á Bearing capacity ratio (BCR)
A comparative study of retentive strengths of zinc phosphate, polycarboxylate and glass ionomer cements with stainless steel crowns - An in vitro study
Journal of Indian Society of Pedodontics and Preventive Dentistry, 2010
An in vitro study was conducted to compare the retentive strengths of zinc phosphate, polycarboxy... more An in vitro study was conducted to compare the retentive strengths of zinc phosphate, polycarboxylate and glass ionomer cements using Instron universal testing machine. Thirty preformed and pretrimmed stainless steel crowns were used for cementation on 30 extracted human primary molars which were divided into three groups of 10 teeth in each group. Then the teeth were stored in artificial saliva and incubated at 37°C for 24 h. A load was applied on to the crown and was gradually increased till the crown showed dislodgement, and then the readings were recorded using Instron recorder and analyzed for statistical significance. The surface area of crown was measured by graphical method. The retentive strength was expressed in terms of kg/cm 2 , which was calculated by the equation load divided by area. Retentive strengths of zinc phosphate (ranged from a minimum of 16.93 to amaximum of 28.13 kg/cm 2 with mean of 21.28 kg/cm 2 ) and glass ionomer cement (minimum of 13.69 - 28.15 kg/cm 2 with mean of 20.69 kg/cm 2 ) were greater than that of polycarboxylate cement (minimum of 13.26 - 22.69 kg/cm 2 with mean of 16.79 kg/cm 2 ). Negligible difference (0.59 kg/cm 2 ) of retentive strength was observed between zinc phosphate (21.28 kg/cm 2 ) and glass ionomer cements (20.69 kg/cm 2 ). Glass ionomer cements can be recommended for cementation of stainless steel crowns because of its advantages and the retentive strength was almost similar to that of zinc phosphate cement.
Sodium fluoroborate glasses were prepared using standard conventional melt-quench technique. Elec... more Sodium fluoroborate glasses were prepared using standard conventional melt-quench technique. Electron paramagnetic resonance (EPR) and optical absorption spectra of Vanadyl ions in different alkali fluoroborate glasses were studied. The spin-Hamiltonian parameters (g and A), Fermi contact interaction parameter (k) and crystal field parameters were evaluated. The values of spin-Hamiltonian parameters confirm that vanadyl ions are present in the glasses as VO 2+ molecular ions in an octahedral site with a tetragonal compression. The optical properties of present glass system were studied from the optical absorption spectra recorded in the wavelength range 200-800 nm. The fundamental absorption edge was identified. The values of optical band gap for direct and indirect allowed transitions and Urbach energies were determined. The effect of alkaline-earth metal on these properties is discussed.
A typical Findings in Appendectomy Specimens: Assessment of 352 Cases
International journal of contemporary surgery, 2016
110 Patients (65 male, & 45 females) who were non-Diabetics, Non-Hypertensive of different ag... more 110 Patients (65 male, & 45 females) who were non-Diabetics, Non-Hypertensive of different age groups were studied 4.1% of male and 2.1% of females developed type-2 diabetics within one 45 days of the appendectomy. Both sexes were belonged to middle class socio-economic status. The age group of the patients was 21to 45 who developed type-2 diabetics. This study creates many ifs and buts that, Diabetics type-2 could be due to both genetic and environmental factors. (1).If appendix is an vestigial organ or immunological in function (2)
A study on management efficiency of sericulturists in North Karnataka
... and old age (11.11%). Suresh (2004) observed that 64.58 per cent of respondents belong to mid... more ... and old age (11.11%). Suresh (2004) observed that 64.58 per cent of respondents belong to middle age followed by young age 17.92 per cent and old age17.50 per cent. Page 12. 2. Education Raghuprasad (1992) conducted ...
The effect of the COVID-19 pandemic on non-elective otolaryngology admissions and a positive change in clinical practice
Annals of The Royal College of Surgeons of England, Jul 1, 2021
As the COVID-19 pandemic progressed across the UK and Northern Ireland in March 2020, our otolary... more As the COVID-19 pandemic progressed across the UK and Northern Ireland in March 2020, our otolaryngology department began to make preparations and changes in practice to accommodate for potentially large numbers of patients with COVID-19 related respiratory illness in the hospital. We retrospectively reviewed the number of non-elective admissions to our department between the months of January and May in 2019 and 2020. A significant reduction in admissions of up to 94% during the months of the pandemic was observed. Our practice shifted to manage patients with epistaxis and peritonsillar abscess on an outpatient basis, and while prospectively collecting data on this, we did not observe any significant adverse events. We view this as a positive learning point and change in our practice as a result of the COVID-19 pandemic.
E3S Web of Conferences
This document provides design principles for concrete beams reinforced with glass fiber reinforce... more This document provides design principles for concrete beams reinforced with glass fiber reinforced polymer (GFRP) bars per the ACI 440.1R-15 regulation. One of the main advantages of using glass fiber reinforced polymer rods instead of traditional steel reinforced rods is their lighter weight and higher corrosion resistance. However, the bending failure mode of FRP reinforced concrete (FRP-RC) beams is brittle rather than ductile because the elasticity of fiber reinforced polymer (FRP) bars is linear until failure and the elongation at break is small. For FRP-RC elements, concrete crushing compression failure, which gives various warnings before failure, is the preferred failure mode. In other words, unlike the usual design practice for reinforced concrete (steel-RC) beams, for FRP-RC beams, an over-reinforced structure is preferable to an under-reinforced structure. In addition, since the FRP RC member has low rigidity of the FRP rod, it bends more and cracks larger than the steel ...
画像処理応用のための有限状態オートマトン採用における新しいアプローチ【JST・京大機械翻訳】
International Journal of Computer Vision, 2018
African Journal of Mathematics and Computer science Research, Aug 31, 2008
Mobile ad hoc networking works properly only if the participating nodes cooperate in routing and ... more Mobile ad hoc networking works properly only if the participating nodes cooperate in routing and forwarding. In this work, the question of how to enable a system to operate despite the presence of misbehavior node is considered. Node misbehavior due to selfish or malicious reasons or faulty nodes can significantly degrade the performance of mobile ad hoc networks. A new protocol called DUAL Factor is proposed to manage with misbehavior nodes. It considers two factors, Direct Factor and Distributed Factor, called DUAL Factor. The DUAL Factor protocol works as an extension to a reactive source-routing protocol for mobile ad-hoc networks. The performance analysis of DUAL Factor is done by comparing it to the standard DSR protocol. It shows that a network with DUAL Factor and up to 60% of misbehaving nodes behaves almost same as a caring network, in sharp contrast to a standard DSR network. All simulations have been implemented and performed in ASIM Simulator.
The NASA Office of Aeronautics and Space Technology (OAST) has established the goal of providing ... more The NASA Office of Aeronautics and Space Technology (OAST) has established the goal of providing a technology base so that NASA can accomplish future missions with a several-orders-of-magnitude increase in mission effectiveness at reduced cost. To realize this goal, a highly focused program must be established advancing technologies that promise substantial increases in capability and/or substantial cost savings. The Study Group on Machine Intelligence and Robotics was established to assist NASA technology program planners to determine the potential in these areas. Thus, the Study Group had the f o l l o w i n g objectives: (1) To identify opportunities for the application of machine intelligence and robotics in N A S A missions and systems. (2) To estimate the benefits of successful adoption of machine intelligence and robotics techniques and to prepare forecasts of their g r o w t h potential. (3) To recommend program options for research, advanced development and implementation o...
Diabetes mellitus is a common condition where physicians come across daily. Though the management... more Diabetes mellitus is a common condition where physicians come across daily. Though the management of diabetes is quite a simple task for physicians, it occasionally manifests in a very uncommon patterns very difficult to correlate them with diabetes, one such being the hemichorea. Hemichorea alone can be the sole manifestation of a variety of non-neurological conditions, such as metabolic derangements. Hemichorea as the first presentation of type 2 diabetes mellitus has been very rarely described. This case depicts the association highlighting that especially in elder patients with newly diagnosed hemichorea, non-ketotic hyperglycemia should promptly be recognized even though CT and MRI scan of brain might be normal.
Disruption tolerant networks (DTNs) are characterized by low node density, unpredictable node mob... more Disruption tolerant networks (DTNs) are characterized by low node density, unpredictable node mobility, and lack of global network information. Most of current research efforts in DTNs focus on data forwarding, but only limited work have been done on providing efficient data access to mobile users. We propose a novel approach to support cooperative caching in DTNs, which enables the sharing and coordination of cached data among multiple nodes and reduces data access delay. Our basic idea is to intentionally cache data at a set of network central locations (NCLs), which can be easily accessed by other nodes in the network. An efficient scheme that ensures appropriate NCL selection based on a probabilistic selection metric and coordinates multiple caching nodes to optimize the tradeoff between data accessibility and caching overhead.
Clinical outcomes of switching antiplatelet therapy from prasugrel to clopidogrel after 3–6 months of percutaneous coronary intervention with drug-eluting stents: A preliminary study
Introduction: Dual antiplatelet therapy comprising aspirin and a P2Y12-receptor inhibitor for 1 y... more Introduction: Dual antiplatelet therapy comprising aspirin and a P2Y12-receptor inhibitor for 1 year is the recommended treatment for the prevention of recurrent thrombotic events in patients who have undergone percutaneous coronary intervention (PCI) with the implantation of drug-eluting stent (DES). Objectives: To assess the safety and efficacy of switching the subjects from prasugrel to clopidogrel after 3–6 months of PCI with DES. Materials and methods: It is a single-center, prospective study conducted in a tertiary care hospital. The study included 100 subjects who underwent PCI with DES using prasugrel as the initial antiplatelet agent along with aspirin. Between 3 and 6 months after PCI, the patients were switched from prasugrel to clopidogrel without a loading dose. These subjects were followed up at day 28 and day 90 after switch for adverse events. Results: The mean age of subjects was 52.58±10.14 years. Of the total subjects, 59% were male and 41% were female. Approximat...
Comparison of Suture Anchors and Pull-Out Sutures for Tendon Attachments to the Distal Phalanx – a Biomechanical Study in Vitro
Three methods to reattach avulsed finger flexor tendons to the distal phalanx were compared: a 1.... more Three methods to reattach avulsed finger flexor tendons to the distal phalanx were compared: a 1.8 mm metal barbed suture anchor, twin 1.3 mm PLA (polylactic acid)absorbable anchors, or a pull-out suture over a button. The suture-anchor interface was tested by pulling the suture at 0, 45, and 90 degrees to the anchor’s axis. The anchors were tested similarly in plastic foam bone substitute. Repairs of transected tendons in cadaveric fingers were loaded cyclically, then to failure. The suture failed prematurely if pulled across the axis of the anchor. Conversely, fixation in bone substitute was stronger when pulling at an angle from the axis. Cyclic loads caused significantly more gap formation in-vitro with twin 1.3 mm absorbable anchors than the other methods; this method was significantly weaker. The 1.8 mm anchor gave similar performance to the pull-out suture over button technique, while the twin 1.3 mm absorbable anchors were weaker and vulnerable to gap formation even with pas...
Journal of Evolution of medical and Dental Sciences, 2014
Malignant mesothelioma is an asbestos-induced, highly aggressive tumor. Malignant mesothelioma is... more Malignant mesothelioma is an asbestos-induced, highly aggressive tumor. Malignant mesothelioma is a tumor of the serosal cavities most commonly involving the pleura and tends to present at relatively advanced stages. We describe a case of (epithelial) type of malignant mesothelioma of pleura in an elderly lady from a rural background with no history of exposure to asbestos, presented with left encysted hemothorax initially suspected to be due to trauma which later turned out to be due to malignant mesothelioma.
The design process of a holistic control system for a MMC to feed variable-speed drives is propos... more The design process of a holistic control system for a MMC to feed variable-speed drives is proposed in this paper.The performance of the control system is finally validated by measurements on a lowvoltage MMC prototype, which feeds a field-oriented controlled induction machineFor high-power drive applications the modular multilevel converter (MMC) is an upcoming topology especially in the medium voltage range. First,from the analysis of the equivalent circuits the design of the current control for the independent adjustment of several current components is derived. Second, the current and voltage components by the investigation of the transformed arm power components for balancing the energies in the arms of the MMC are identified systematically. At minimum necessary internal currents over the complete frequency range The control system ensures a dynamic balancing of the energies in the cells of the MMC. Simultaneously, all other circulating current components are avoided to minimize current stress and additional voltage pulsations.. Here we are using the fuzzy controller compared to other controllers i.e. The fuzzy controller is the most suitable for the human decision-making mechanism, providing the operation of an electronic system with decisions of experts. In addition, using the fuzzy controller for a nonlinear system allows for a reduction of uncertain effects in the system controland improve the efficiency.A cascaded structure with subordinated current control loops and filterbased energy control loops is proposed in this paper.Simulation results are shown below.
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Papers by Rajashekar Reddy