Papers by ROBERTO MÉNDEZ SÁNCHEZ
Healthcare, Dec 20, 2023
This article is an open access article distributed under the terms and conditions of the Creative... more This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY

Research Square (Research Square), Oct 14, 2022
Background The increase in life expectancy and survival time implies an increase in the possible ... more Background The increase in life expectancy and survival time implies an increase in the possible side-effects of pharmacological treatments in these patients. Cancer-related fatigue is one of them. The main objective of this study is to evaluate the effects of a multimodal program of physical exercise and functional rehabilitation on asthenia, pain, functional capacity and quality of life in cancer patients with cancerrelated fatigue. Methods This was a randomized, parallel-controlled clinical trial, with two arms (experimental and control group), and it was conducted over the course of a year in the Oncology Hospitalization Unit at the CAUSA. Participants were assessed at three points during the study. First assessment was prior to hospital discharge, second assessment was after 15 days, and nal assessment was at one-month post-hospital follow-up. The main variables to be studied are the dependency levels (Barthel), cancer-related fatigue (FACT-An), health-related quality of life (EuroQoL-5D), functional capacity (SPPB) and kinesiophobia (TSK-F). Results Sample size (n = 44). Mean age 63.46 ± 12.36 years. Signi cant differences between control and experimental group participants in Barthel, FACT-An, TSK-F and SPPB scores (p = 0.000) at follow-up and nal assessment. Conclusions There are bene cial effects of a multimodal physical exercise and functional rehabilitation program in improving the autonomy of cancer-related fatigue patients. Trials registration: The clinical trial was registered in ClinicalTrials.gov (NCT04761289).

Nutrients
The objective of this study was to evaluate the effects of consuming 50 g of raisins on cognitive... more The objective of this study was to evaluate the effects of consuming 50 g of raisins on cognitive performance, quality of life, and functional activities in healthy older adults. This is a parallel randomized controlled clinical trial, in which 80 subjects over 70 years of age participated. For 6 months, the intervention group (IG; n = 40) consumed 50 g of raisins per day added to their usual diet, whereas the control group (CG; n = 40) received no supplement. All variables were measured at baseline and at 6 months. Cognitive performance assessed with the Montreal Cognitive Assessment (MOCA) test shows a difference of 3.27 points (95% CI 1.59 to 4.96), p ≤ 0.001, favorable to the IG, after the intervention. Among the cognitive performances, an improvement is observed in the IG in orientation, assessed both with the MOCA test 0.49 (95% CI 0.10 to 0.87), p = 0.014, and with the Mini-Mental State Examination (MMSE) test, 0.36 (95% CI 0.02 to 0.70), p = 0.038. In visuospatial/executive ...
European Journal of Physical and Rehabilitation Medicine

BMC Geriatrics
Background Polyphenols have been shown to be effective against many chronic diseases, including n... more Background Polyphenols have been shown to be effective against many chronic diseases, including neurodegenerative diseases. Specifically, the consumption of raisins, being a food rich in polyphenols, has been attributed with neuroprotective benefits. Therefore, our main objective is to evaluate the effect of including 50 g of raisins in the diet daily for 6 months, on the improvement of cognitive performance, cardiovascular risk factors and markers of inflammation in a population of older adults without cognitive impairment. Methods Design and intervention: This study will be a randomized controlled clinical trial of two parallel groups. Each subject included in the study will be randomly assigned to one of two study groups: control group (no supplement), intervention group (50 g of raisins daily during 6 months). Study population: The participants will be selected by consecutive sampling in the Primary Care consultations of urban health centers in Salamanca and Zamora (Spain), taki...

Life
Temporomandibular disorders are a common pathology affecting up to 70% of the population, with a ... more Temporomandibular disorders are a common pathology affecting up to 70% of the population, with a maximum incidence in young patients. We used a sample of twenty patients recruited in the Maxillofacial Surgery Service of the University Hospital of Salamanca (Spain), who met the inclusion criteria, with unilateral painful symptomatology of more than three months’ duration. All patients were randomly treated by intramuscular and intra-articular injections of botulinum toxin (100 U) in eight predetermined points. Pain symptomatology was assessed by the visual analog scale (VAS) at the different locations, together with joint symptomatology, at baseline and six weeks after treatment. Adverse effects were also evaluated. In 85% of the patients, pain upon oral opening improved and 90% showed improvement in pain upon mastication. A total of 75% of the patients reported improvement in joint clicking/noise. Headaches improved or disappeared in 70% of the patients treated. Despite the limitati...

Manual Therapy, 2009
Our aim was to examine the effects of a seated thoracic spine distraction thrust manipulation inc... more Our aim was to examine the effects of a seated thoracic spine distraction thrust manipulation included in an electrotherapy/thermal program on pain, disability, and cervical range of motion in patients with acute neck pain. This randomized controlled trial included 45 patients (20 males, 25 females) between 23 and 44 years of age presenting with acute neck pain. Patients were randomly divided into 2 groups: an experimental group which received a thoracic manipulation, and a control group which did not receive the manipulative procedure. Both groups received an electrotherapy program consisting of 6 sessions of TENS (frequency 100 Hz; 20 min), superficial thermotherapy (15 min) and soft tissue massage. The experimental group also received a thoracic manipulation once a week for 3 consecutive weeks. Outcome measures included neck pain (numerical pain rate scale; NPRS), level of disability (Northwick Park Neck Pain Questionnaire; NPQ) and neck mobility. These outcomes were assessed at baseline and 1 week after discharge. A 2-way repeated-measures ANOVA with group as between-subject variable and time as within-subject variable was used. Patients receiving thoracic manipulation experienced greater reductions in both neck pain, with between-group difference of 2.3 (95% CI 2e2.7) points on a 11-NPRS, and perceived disability with between-group differences 8.5 (95% CI 7.2e9.8) points. Further, patients receiving thoracic manipulation experienced greater increases in all cervical motions with between-group differences of 10.6 (95% CI 8.8e12.5) for flexion; 9.9 (95% CI 8.1e11.7) for extension; 9.5 (95% CI 7.6e11.4) for right lateral-flexion; 8 (95% CI 6.2e9.8) for left lateral-flexion; 9.6 (95% CI 7.7e11.6) for right rotation; and 8.4 (95% CI 6.5e10.3) for left rotation. We found that the inclusion of a thoracic manipulation into an electrotherapy/ thermal program was effective in reducing neck pain and disability, and in increasing active cervical mobility in patients with acute neck pain.

Journal of Manipulative and Physiological Therapeutics, 2012
Chronic rhinosinusitis (CRS) is thought to develop through an inadequate drainage of nasal and si... more Chronic rhinosinusitis (CRS) is thought to develop through an inadequate drainage of nasal and sinus secretions and perpetuated by local mechanical and autonomic nervous system factors. Manual therapy may have an effect on these factors providing symptomatic relief of CRS symptoms. The purpose of this prospective case series was to report the results of manual therapy on a set of patients with craniofacial pain and a diagnosis of CRS. Fourteen consecutive patients presenting with a primary report of craniofacial pain and a diagnosis CRS completed self-report questionnaires including the Sinonasal Assessment Questionnaire, Rhinosinusitis Task Force, visual analog scale for craniofacial pain, and pressure pain threshold over 4 sinus points on the face. Patients were seen once a week for 7 consecutive weeks and completed all outcome measures at baseline and subsequent weekly sessions. They received manual therapy interventions only on the second, third, and fifth weekly sessions. No significant changes in outcome measures were observed from baseline to 1 week, where no intervention was applied. Significant improvements were observed on all outcome measures (Ps ≤ .015) for pre- and post-first treatment session, as well as from baseline to 7 weeks (Ps < .001). All patients exhibited a significant decrease in craniofacial pain and increased pressure pain thresholds and reported less severity of their symptoms. Patients with craniofacial pain and CRS who were treated with manual therapy demonstrated improvements in all outcome measures only after each treatment session. Our results suggest that manual therapy treatment could be considered as an appropriate alternative treatment of CRS.

The Journal of Alternative and Complementary Medicine, 2010
Objective: The objective of this study was to assess the immediate effect of a sciatic nerve slid... more Objective: The objective of this study was to assess the immediate effect of a sciatic nerve slider technique added to sustained hamstring stretching on lumbar and lower quadrant flexibility. Design: This was a randomized controlled pilot study. Subjects: Eight (8) healthy male soccer players (21 AE 3 years) were randomly assigned to 2 groups. Interventions: Group A received 5 minutes of bilateral sustained hamstring stretching. Group B additionally received 60 seconds of a sciatic nerve slider technique for each leg. Outcomes: Pre-and postintervention outcomes taken by an assessor blinded to the treatment allocation of the participants included metric distance on finger-to-floor, sit and reach, and the modified Schö ber tests and goniometric range of each hip for the straight-leg raise and each knee for seated slump test. Baseline betweengroup differences were examined with an independent t test and a two-way repeated-measures analysis of variance with p < 0.05 and p < 0.025 analyzed effects of the interventions. Results: There were no significant between-group baseline differences (p > 0.2). There was a significant effect for time on all outcomes (p < 0.01) other than the sit and reach test (p ¼ 0.8). A significant interaction between group time with greater improvements in group B was found for the modified Schö ber test (F ¼ 5.5; p < 0.05), left straight-leg raise (F ¼ 6.1; p < 0.05) and slump test in either leg (left F ¼ 28.7; p ¼ 0.002; right F ¼ 4.9; p < 0.05). Conclusions: Adding a sciatic nerve slider technique to sustained hamstring stretching led to greater immediate increases in both lumbar and lower quadrant flexibility in young healthy soccer players as measured by four of the seven outcomes used. Study limitations and suggestions for future studies are discussed.
Métodos específicos de intervención en fisioterapia, 2015, ISBN 978-84-9835-943-5, págs. 233-244, 2015

Revista Brasileira de Medicina do Esporte, 2008
OBJETIVO: Verificar a influência da suplementação de vitaminas antioxidantes na dieta de mulheres... more OBJETIVO: Verificar a influência da suplementação de vitaminas antioxidantes na dieta de mulheres idosas que praticam exercícios físicos regulares, sobre o estresse oxidativo, indicadores da saúde física e risco de enfermidades cardiovasculares (ECV). MÉTODO: Foram observados dois grupos (S e C) de mulheres com idades entre 60 e 80 anos participantes de um programa de atividades físicas durante 58 semanas, com freqüência de três vezes por semana e duração de 50 a 55 minutos cada sessão. A dieta habitual do Grupo S (n=36) foi suplementada diariamente com 330 ml de uma bebida antioxidante (FuncionaTM); o Grupo C (n=32) ingeriu água e se caracterizou como controle. Como indicadores do estresse oxidativo foram determinadas as concentrações plasmáticas de glutationa reduzida (GSH) e oxidada (GSSG), calculada a relação molar GSH/GSSG, e identificado o dano oxidativo em lipídios e proteínas. As condições físicas e cardiovasculares foram avaliadas por meio dos parâmetros antropométricos hab...
Memoria ID-0175. Ayudas de la Universidad de Salamanca para la innovacion docente, curso 2014-2015.
Memoria ID12-0304. Ayudas de la Universidad de Salamanca para la innovacion docente, curso 2012-2... more Memoria ID12-0304. Ayudas de la Universidad de Salamanca para la innovacion docente, curso 2012-2013.

Medicine, 2020
Introduction: Reduced bone mineral density and increased risk of falls are related with Alzheimer... more Introduction: Reduced bone mineral density and increased risk of falls are related with Alzheimer disease, and these increase likelihood of bone osteoporotic fractures causing serious complications such as disability, fear of falling, loss autonomy, decreased quality of life, and anticipated mortality in elderly patients. Gait and balance disturb are 2 factors to favor falls in elderly, and in patients with cognitive impairment, the risk of falls increases to double. Exercise and Mediterranean diet produce beneficial effects for aging, cognitive decline, and are widely recommended to reduce the effects of osteoporosis, fall risk, and related fragility fractures. The primary objective of this study is to evaluate the short and medium-term effects during 6 months, of a multicomponent physical exercise program with a Mediterranean diet on bone mineral density, fall risk, balance, and gait by a controlled clinical trial in patients with Alzheimer disease. Methods: The study is a 6-month...
Memoria ID-0176. Ayudas de la Universidad de Salamanca para la innovacion docente, curso 2014-2015.
Memoria ID12-0305. Ayudas de la Universidad de Salamanca para la innovacion docente, curso 2012-2... more Memoria ID12-0305. Ayudas de la Universidad de Salamanca para la innovacion docente, curso 2012-2013.
Memoria ID-179. Ayudas de la Universidad de Salamanca para la innovacion docente, curso 2013-2014.

Resumen Introduccion Las caidas constituyen uno de los sindromes mas importantes en geriatria. El... more Resumen Introduccion Las caidas constituyen uno de los sindromes mas importantes en geriatria. El objetivo es conocer la incidencia de caidas durante 5 anos en una poblacion de mujeres que participan anualmente en un programa de revitalizacion geriatrica. Material y metodos Estudio de cohortes con seguimiento de 5 anos de 137 mujeres con edades comprendidas entre los 60 y los 90 anos (media ± DT: 71,65 ± 5,58 anos), que participaron periodicamente en un programa de revitalizacion geriatrica desarrollado durante 9 meses al ano. Se registran en cada periodo el numero de caidas, la talla, el peso y la asistencia al programa. Se calcularon la incidencia y la tasa de caidas durante el seguimiento y el riesgo de volverse a caer. Se estudio la relacion entre la edad y la asistencia al programa. Resultados Se registraron 207 caidas en 84 mujeres distintas. Incidencia de caidas a los 5 anos: de 1,51 caidas/mujer. El 40% no se cayo ninguna vez en todo el periodo. El porcentaje anual de mujeres que se cayeron alguna vez vario entre el 21,2 y el 26,3%, y el de las que se cayeron 2 o mas veces, entre el 0,7 y el 5%. Se registro una reduccion en la tasa de caidas durante los periodos de actividad. La asistencia media oscilo entre el 75 y el 83%. No se encontro relacion significativa entre la asistencia ni la edad y el hecho de caerse. Conclusiones La incidencia de caidas en la poblacion de estudio es inferior a la reportada en la literatura para el mismo segmento de la poblacion. Los estudios que incluyen revitalizacion geriatrica como posible herramienta en la prevencion de la discapacidad y el mantenimiento de la calidad de vida en las personas mayores son necesarios.
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Papers by ROBERTO MÉNDEZ SÁNCHEZ