U Hrvatskoj je u razdoblju 1990.-1999. godine porastao broj novih slucajeva raka s 16.318 na 21.8... more U Hrvatskoj je u razdoblju 1990.-1999. godine porastao broj novih slucajeva raka s 16.318 na 21.893, tj. u prosjeku za 445.6 (2.7%) godisnje, a broj umrlih s 10.777 u 1990. na 11.725 u 2000.godini, tj. u prosjeku za 130.9 (1.2%) godisnje. Slican rast je zabilježen i u Osjecko- baranjskoj županiji (3% vise novih slucajeva i 2% vise umrlih godisnje.)Incidencija raka je kod svih vodecih sijela u statisticki znacajnom trendu porasta, osim invazivnog raka vrata maternice, koji u 1999. godini prvi put nije spadao u najcescih 15, sto bi se možda moglo protumaciti radom na njegovom ranom otkrivanju uzimanjem brisa vrata maternice. Hrvatska liga protiv raka i Gradska liga protiv raka Osijek osnovane su 1966. godine i okupljaju građane volontere, zdravstvene djelatnike, strucne i drustvene institucije i udruge građana u programima koji potpomažu aktivnosti zdravstvene službe u zastiti stanovnistava od malignih bolesti.Kao glavni zadaci zacrtani su zdravstveni odgoj i prosvjecivanje stanovnist...
Hrvatska se nalazi na visokom mjestu među europskim državama po prosirenosti i smrtnosti od malig... more Hrvatska se nalazi na visokom mjestu među europskim državama po prosirenosti i smrtnosti od malignih bolesti. Iskustva razvijenih zemalja pokazala su da se implementacijom programa primarne prevencije i ranog otkrivanja raka, na nacionalnoj razini, može znacajno smanjiti mortalitet od raka i poboljsati kvalitetu života oboljelih. U Hrvatskoj je 2. Studenog 2006. God. Zapocela primjena Programa skrininga raka dojke, kao dio prihvacenoog Nacionalnog programa prevencije i ranog otkrivanja raka najcescih lokalizacija: dojke, debelog crijeva, grlica maternice i prostate. U Hrvatskoj je rak dojke najcesce sijelo i vodeci uzrok smrti od raka u žena sa stopom incidencije od 100, 1/100.000 žena ( 2005. ) i stopom mortaliteta od 36, 1/100.000 žena ( 2006. ). U Osjecko-baranjskoj županiji je 2005. Incidencija raka dojke iznosila 99, 5/100.000, a mortalitet 43, 6/100.000( 2006. ). I incidencija i mortalitet od raka dojke, u Hrvatskoj, u stalnom su porastu. Linearni trendovi stopa incidencije i ...
This retrospective study was undenaken to identify the cause of death in patients hospitalized at... more This retrospective study was undenaken to identify the cause of death in patients hospitalized at the Osijek University Hospital, referred by the psysicians from the Beli Manastir Health Center Emergency Unit to the Osijek Department of Neurology for a clinical manifestations of cerebrovascular disease (CVD). From November 1, 1997 (the time of Baranya reintegration after the war) til December 31, 2001, 229 patients with symptoms of CVD were referred to the Osijek University Hospital from Baranya and 89 of them died in hospital. Among these 89 patients, there were 53 men and 36 women, mean age 68, 73 years. The majority of patients were in the 61-70 (n=34) and 71-80 (n=34) age groups. The cause of death was determined on the basis of clinical diagnosis, computed tomography finding, and autopsy finding. Stroke, as the eause of death, was identified in 81 deceased patients, with lethality of 38, 38%, whereas the remaining 8 deceased patients with the symptoms of CVD died of some other disease (plasmocytoma, glioblastoma, cerebral metestases, fracture of the first cervical vertebra, acute myocardial infarction, acute appendicitis, chronical ishemic heart disease and bleeding gastric ulcer). Out of 81 stroke patients, ischemic stroke was diagnosed in 59 and hemorrhaglc stroke in 22 patients. Comparison of referral diagnoses and causes of death showed that of 72 patients referred with a diagnosis of nonspecified stroke, 47 died from ischemic strake, 18 from hemorrhagic stroke and 7 from other diseases. Out of seven patients referred as ischemic stroke, ischemic stroke was the cause of death in 6 and hemorrhagic stroke in one patient. Out of five patients referred as hemorrhagic stroke, hemorrhagic type was cause of death in 3, ischemic stroke in one and other disease in one patient. In the patients referred with diagnosis of transient ischemic attack (n=1), hypertensive encelophathy (n=2) and late stroke sequel (n=2), the cause of death was ischemic stroke.
Electrogastrography (EGG) is a method of recording and interpretation of gastric electrical activ... more Electrogastrography (EGG) is a method of recording and interpretation of gastric electrical activity. Because of its ease to use, cutaneous EGG has gained wide acceptance. The electric activity of stomach is corelated to its contractile activity.Gallstones usually don't cause chronic dyspepsia as is known from literature but billiary colic and dyspepsia are very common in adult population of patients with cholelithiasis.The aim of this study was to evaluate the effect of cholelithiasis on gastric electric activity (GEA) wich was recorded via transcutaneous electrogastrography. The study is included 10 patients (M/F: 5/5 ; Age: 52, 20±6.29 years ; BMI: 28, 69±1, 36 kg/m2) with cholecystolithiasis diagnosed by transabdominal ultrasound and none of them had parameters of cholecystitis. Exclusion criteria were history of abdominal surgery, malignancy, non ulcer dyspepsia, cardiovascular, pulmonal or other diseases as well as hystory of functional gastrointestinal disorders.The EGG f...
National colorectal cancer early detection program Colorectal cancer is the second leading cause ... more National colorectal cancer early detection program Colorectal cancer is the second leading cause of cancer death in Europe. Its estimated incidence in 2006 was 413 000, while the mortality was 335 000. In 2005, in Croatia, there were 2 843 new cases, and 1 800 deaths. The implementation of faecal occult blood test for colorectal cancer screening in controlled studies, in the USA, UK, Denmark and Sweden, reduced the relative mortality rate from 18% to 33%. The colorectal cancer screening is efficient in colorectal cancer prevention, because the time of benign to malignant transformation lasts for ten and more years. National colorectal cancer early detection program began on november 1. 2007. Its aim is to reduce the mortality from colorectal cancer for at least 15% in five years after its start, to include at least 60% of those called for the screening, to detect cancer in early stages, and to achieve coverage of risk groups in the population of 75% by 2015. The target group are men...
Pretilost je poznat i dokazan rizicni faktor za nastanak secerne bolesti.Istraživanje je trebalo ... more Pretilost je poznat i dokazan rizicni faktor za nastanak secerne bolesti.Istraživanje je trebalo potvrditi hipotezu prema kojoj skolska djeca sa povisenim BMI (body mass index) iskazuje povecane vrijednosti secera u krvi, iako jos ne postoje klinicki znakovi bolesti. Metodom potpunog obuhvata pregledano je 321 skolske djece sela Josipovac.Svim ucenicima izmjerena je visina i težina te izracunat BMI , iskazan u percentilima prilagođenim dobi i spolu djeteta.110 djece (34, 27% )imalo je povecane vrijednosti BMI:djecaci 52 ispitanika ili (47, 28%) djevojcica 58 ispitanika ili( 52, 72% ). Svim ucenicima sa povecanim vrijednostima BMI izmjeren je secer u krvi nataste. Dobivene su povisene vrijednosti kod 21 ispitanika (19, 09%).Njima je ucinjena pretraga OGTT (Oral Glucose Tolerance Test- određivanje glukoze nataste i 120 minuta poslije uzimanja 75 gr glukoze u 250 ml vode) nakon cega je 7 djece (6, 36% )rizicnih evidentirano kao oboljeli od secerne bolesti te upuceno na daljnu proces dijagnostike lijecenja. Istraživanje je dokazalo vrijednosti preventivnih, screening mjera u ranom otkrivanju secerne bolesti te se preporucuje kao jeftin i pouzdan postupak u screeningu sire populacije.
Introduction: We analysed health status of returnees in places of Osijek Region from which reside... more Introduction: We analysed health status of returnees in places of Osijek Region from which residents escaped during the war in Croatia. High prevalence of diabetes was found. We hypothesized that short health education, aimed at changing lifestyles, could be feasible method for use in the population setting. Methods: In order to evaluate the outcomes of such intervention, respondents were checked for health parameters twice, prior the intervention and six month after the intervention. Total of 202 adult persons responded They were also asked about their eating habits, physical activity and dietary patterns. Results: Six months after the intervention respondents generally showed significant weight reduction (values for body mass index are 29.02 and 25.69 kg/cm2 respectively) and improvement in glycemic control (values for serum glucose are 7.01 and 6.46 mmol/L respectively) (t-test). By the selection of respondents in categories according to the starting values of their health parameters, we could recognize that particular subgroups of respondents are less adherent to education intervention than some others. The intervention increased physical activity, mainly as the result of increase in readiness of the previously hesitating subgroup of respondents (Pearson chi-square test). Dietary patterns were partially changed, depending on low finance of returnees. Conclusions: A short counseling about healthy lifestyles is feasible as an intervention method in the population at high risk for diabetes. However, it was brought to our attention that such intervention should be as much as possible individualy oriented, considering many personal and social characteristics of an individual.
The perception of obesity among people has not changed significantly regardless numerous public e... more The perception of obesity among people has not changed significantly regardless numerous public educational programs. Reasons for obesity pandemics are numerous and complex, but can be mostly resumed to life-style changes. The aim of this research was to determine connection between socioeconomic factors and obesity with children of our region. Study included pupils aged 7-8 from 19 first grades in 8 primary schools in Osijek-Baranya County. Body height and weight were measured and socioeconomic data status were collected. Socioeconomic status included data on marital status, educational level, employment, number of children in the family, kindergarten attendance and urban/rural location and also smoking habits of parents. BMI was calculated as a parameter for obesity assessment according to Croatian reference values. Total of 372 children were measured. There were 6.5% of overweight children (BMI between 90th and 97th percentile) and 2.4% of obese children (BMI above 97th percentile). The prevalence of obese children in our research was 8.9%. Obesity is not influenced by rural/urban residence, marital status of parents, number of children in the family, mother's education, or by parents' smoking habits. Positive correlation between obesity and father's education and parents' unemployment was found. Available literature data, same as our study, did not show consistent association between socioeconomic factors and obesity with children. Contradictory results of different studies can be a result of a small sample, difference in study design and different criteria for defining categories within investigated socioeconomic factor.
Numerous studies suggested that sex-hormones could influence cognitive function in women, in life... more Numerous studies suggested that sex-hormones could influence cognitive function in women, in lifetime, but inconsistency in their impact during different phases of menstrual cycle (1-3). In addition, results on the role of progesterone are scarce (4). Here we addressed several methodological problems recognized in published studies: a) inappropriate selection of cycle phases, b) a large inter-individual variability in cognitive function, due to non-homogenous groups of subjects which could affect the reliability of results’ interpretation ; and c) measurement of sex hormones concentrations in blood with standardized tests (5). The aim of this study was to exactly determine the phase of cycle and to evaluate the role of sex hormones in modulation of specific cognitive function. Sixteen healthy, normal cycling female medical students aged 22-24 (M = 23 SD = 0.85) volunteered to participate in this study. The study was approved by the Ethical Committee of the Medical School Osijek, Croatia.Cognitive tasks were performed in three different phases of menstrual cycle (EF - early follicular phase, day 2-4 ; O - proven ovulatory phase and ML – mid-luteal phase, 7 – 9 days after ovulation). To appoint the date of ovulation ELISA-based LH urinary strips were used. Hormone levels (E2 - estrogen, P-progesterone, LH and FSH) were assessed from venous blood to confirm menstrual cycle phases. Values are presented as means±SEM, compared by One way ANOVA repeated measures, post hoc Tukey and Holm-Sidac tests, when appropriate (SigmaStat 3.5). Interestingly, all tested women showed above average results in performed tasks for cognitive function evaluation, independently of type of test. The results of hormone levels have shown that the cognitive tasks were done at appropriate points of menstrual cycle. LH and E2 were highest in O phase ; the highest P level in ML phase of cycle (Table 1). There was no significant difference in immediate and delayed recall, implicate or explicate memory and verbal fluency among any phases of menstrual cycle. However, there was significantly better performance in attention task (given as total score) in ML phase (580.38±15.23) compared to the EF (519±19.19) and the O (547.13±16.35) phase of the cycle (p=0.001), with highest P levels, suggesting that attention task performance could be influenced by progesterone. The results in attention task are not related to the changes in E2 levels. Furthermore, there is no enough valid proof for the role of E2 in the modification of cognitive function in women over the length of cycle.
Timovi obiteljske medicine i patronažne sestre u okviru Doma zdravlja Osijek jos od 1996. god. ko... more Timovi obiteljske medicine i patronažne sestre u okviru Doma zdravlja Osijek jos od 1996. god. kontinuirano provode program mjera zdravstvenog odgoja dijabetickih bolesnika, s ciljem postizanja bolje kontrole te bolesti, koja u Osjecko- baranjskoj županiji konstantno pokazuje visoku zastupljenost, vecu od prosjeka za Hrvatsku. Vođeni vlastitim pozitivnim iskustvom, te na osnovu preporuka iz znanstvene literature o tome da zdravstvena edukacija ima jos bolje ucinke u prevenciji, nego u kontroli dijabetesa, pristupili smo izradi i ovoga istraživanja. Naime, analiza zdravstvenog stanja povratnika u naselja Istocne Slavonije, iz kojih je za vrijeme Domovinskog rata izbjeglo stanovnistvo, ucinjena na stratificiranom uzorku od 519 odraslih osoba, je ukazala na veliku zastupljenost dijabetesa i kardiovaskularnih bolesti u toj populacijskoj skupini, cak vecu i od prosjeka za Istocnu Slavoniju i za Hrvatsku. Zbog toga se odmah pristupilo provođenju programa mjera za suzbijanje cinitelja rizi...
U Hrvatskoj je u razdoblju 1990.-1999. godine porastao broj novih slucajeva raka s 16.318 na 21.8... more U Hrvatskoj je u razdoblju 1990.-1999. godine porastao broj novih slucajeva raka s 16.318 na 21.893, tj. u prosjeku za 445.6 (2.7%) godisnje, a broj umrlih s 10.777 u 1990. na 11.725 u 2000.godini, tj. u prosjeku za 130.9 (1.2%) godisnje. Slican rast je zabilježen i u Osjecko- baranjskoj županiji (3% vise novih slucajeva i 2% vise umrlih godisnje.)Incidencija raka je kod svih vodecih sijela u statisticki znacajnom trendu porasta, osim invazivnog raka vrata maternice, koji u 1999. godini prvi put nije spadao u najcescih 15, sto bi se možda moglo protumaciti radom na njegovom ranom otkrivanju uzimanjem brisa vrata maternice. Hrvatska liga protiv raka i Gradska liga protiv raka Osijek osnovane su 1966. godine i okupljaju građane volontere, zdravstvene djelatnike, strucne i drustvene institucije i udruge građana u programima koji potpomažu aktivnosti zdravstvene službe u zastiti stanovnistava od malignih bolesti.Kao glavni zadaci zacrtani su zdravstveni odgoj i prosvjecivanje stanovnist...
Hrvatska se nalazi na visokom mjestu među europskim državama po prosirenosti i smrtnosti od malig... more Hrvatska se nalazi na visokom mjestu među europskim državama po prosirenosti i smrtnosti od malignih bolesti. Iskustva razvijenih zemalja pokazala su da se implementacijom programa primarne prevencije i ranog otkrivanja raka, na nacionalnoj razini, može znacajno smanjiti mortalitet od raka i poboljsati kvalitetu života oboljelih. U Hrvatskoj je 2. Studenog 2006. God. Zapocela primjena Programa skrininga raka dojke, kao dio prihvacenoog Nacionalnog programa prevencije i ranog otkrivanja raka najcescih lokalizacija: dojke, debelog crijeva, grlica maternice i prostate. U Hrvatskoj je rak dojke najcesce sijelo i vodeci uzrok smrti od raka u žena sa stopom incidencije od 100, 1/100.000 žena ( 2005. ) i stopom mortaliteta od 36, 1/100.000 žena ( 2006. ). U Osjecko-baranjskoj županiji je 2005. Incidencija raka dojke iznosila 99, 5/100.000, a mortalitet 43, 6/100.000( 2006. ). I incidencija i mortalitet od raka dojke, u Hrvatskoj, u stalnom su porastu. Linearni trendovi stopa incidencije i ...
This retrospective study was undenaken to identify the cause of death in patients hospitalized at... more This retrospective study was undenaken to identify the cause of death in patients hospitalized at the Osijek University Hospital, referred by the psysicians from the Beli Manastir Health Center Emergency Unit to the Osijek Department of Neurology for a clinical manifestations of cerebrovascular disease (CVD). From November 1, 1997 (the time of Baranya reintegration after the war) til December 31, 2001, 229 patients with symptoms of CVD were referred to the Osijek University Hospital from Baranya and 89 of them died in hospital. Among these 89 patients, there were 53 men and 36 women, mean age 68, 73 years. The majority of patients were in the 61-70 (n=34) and 71-80 (n=34) age groups. The cause of death was determined on the basis of clinical diagnosis, computed tomography finding, and autopsy finding. Stroke, as the eause of death, was identified in 81 deceased patients, with lethality of 38, 38%, whereas the remaining 8 deceased patients with the symptoms of CVD died of some other disease (plasmocytoma, glioblastoma, cerebral metestases, fracture of the first cervical vertebra, acute myocardial infarction, acute appendicitis, chronical ishemic heart disease and bleeding gastric ulcer). Out of 81 stroke patients, ischemic stroke was diagnosed in 59 and hemorrhaglc stroke in 22 patients. Comparison of referral diagnoses and causes of death showed that of 72 patients referred with a diagnosis of nonspecified stroke, 47 died from ischemic strake, 18 from hemorrhagic stroke and 7 from other diseases. Out of seven patients referred as ischemic stroke, ischemic stroke was the cause of death in 6 and hemorrhagic stroke in one patient. Out of five patients referred as hemorrhagic stroke, hemorrhagic type was cause of death in 3, ischemic stroke in one and other disease in one patient. In the patients referred with diagnosis of transient ischemic attack (n=1), hypertensive encelophathy (n=2) and late stroke sequel (n=2), the cause of death was ischemic stroke.
Electrogastrography (EGG) is a method of recording and interpretation of gastric electrical activ... more Electrogastrography (EGG) is a method of recording and interpretation of gastric electrical activity. Because of its ease to use, cutaneous EGG has gained wide acceptance. The electric activity of stomach is corelated to its contractile activity.Gallstones usually don't cause chronic dyspepsia as is known from literature but billiary colic and dyspepsia are very common in adult population of patients with cholelithiasis.The aim of this study was to evaluate the effect of cholelithiasis on gastric electric activity (GEA) wich was recorded via transcutaneous electrogastrography. The study is included 10 patients (M/F: 5/5 ; Age: 52, 20±6.29 years ; BMI: 28, 69±1, 36 kg/m2) with cholecystolithiasis diagnosed by transabdominal ultrasound and none of them had parameters of cholecystitis. Exclusion criteria were history of abdominal surgery, malignancy, non ulcer dyspepsia, cardiovascular, pulmonal or other diseases as well as hystory of functional gastrointestinal disorders.The EGG f...
National colorectal cancer early detection program Colorectal cancer is the second leading cause ... more National colorectal cancer early detection program Colorectal cancer is the second leading cause of cancer death in Europe. Its estimated incidence in 2006 was 413 000, while the mortality was 335 000. In 2005, in Croatia, there were 2 843 new cases, and 1 800 deaths. The implementation of faecal occult blood test for colorectal cancer screening in controlled studies, in the USA, UK, Denmark and Sweden, reduced the relative mortality rate from 18% to 33%. The colorectal cancer screening is efficient in colorectal cancer prevention, because the time of benign to malignant transformation lasts for ten and more years. National colorectal cancer early detection program began on november 1. 2007. Its aim is to reduce the mortality from colorectal cancer for at least 15% in five years after its start, to include at least 60% of those called for the screening, to detect cancer in early stages, and to achieve coverage of risk groups in the population of 75% by 2015. The target group are men...
Pretilost je poznat i dokazan rizicni faktor za nastanak secerne bolesti.Istraživanje je trebalo ... more Pretilost je poznat i dokazan rizicni faktor za nastanak secerne bolesti.Istraživanje je trebalo potvrditi hipotezu prema kojoj skolska djeca sa povisenim BMI (body mass index) iskazuje povecane vrijednosti secera u krvi, iako jos ne postoje klinicki znakovi bolesti. Metodom potpunog obuhvata pregledano je 321 skolske djece sela Josipovac.Svim ucenicima izmjerena je visina i težina te izracunat BMI , iskazan u percentilima prilagođenim dobi i spolu djeteta.110 djece (34, 27% )imalo je povecane vrijednosti BMI:djecaci 52 ispitanika ili (47, 28%) djevojcica 58 ispitanika ili( 52, 72% ). Svim ucenicima sa povecanim vrijednostima BMI izmjeren je secer u krvi nataste. Dobivene su povisene vrijednosti kod 21 ispitanika (19, 09%).Njima je ucinjena pretraga OGTT (Oral Glucose Tolerance Test- određivanje glukoze nataste i 120 minuta poslije uzimanja 75 gr glukoze u 250 ml vode) nakon cega je 7 djece (6, 36% )rizicnih evidentirano kao oboljeli od secerne bolesti te upuceno na daljnu proces dijagnostike lijecenja. Istraživanje je dokazalo vrijednosti preventivnih, screening mjera u ranom otkrivanju secerne bolesti te se preporucuje kao jeftin i pouzdan postupak u screeningu sire populacije.
Introduction: We analysed health status of returnees in places of Osijek Region from which reside... more Introduction: We analysed health status of returnees in places of Osijek Region from which residents escaped during the war in Croatia. High prevalence of diabetes was found. We hypothesized that short health education, aimed at changing lifestyles, could be feasible method for use in the population setting. Methods: In order to evaluate the outcomes of such intervention, respondents were checked for health parameters twice, prior the intervention and six month after the intervention. Total of 202 adult persons responded They were also asked about their eating habits, physical activity and dietary patterns. Results: Six months after the intervention respondents generally showed significant weight reduction (values for body mass index are 29.02 and 25.69 kg/cm2 respectively) and improvement in glycemic control (values for serum glucose are 7.01 and 6.46 mmol/L respectively) (t-test). By the selection of respondents in categories according to the starting values of their health parameters, we could recognize that particular subgroups of respondents are less adherent to education intervention than some others. The intervention increased physical activity, mainly as the result of increase in readiness of the previously hesitating subgroup of respondents (Pearson chi-square test). Dietary patterns were partially changed, depending on low finance of returnees. Conclusions: A short counseling about healthy lifestyles is feasible as an intervention method in the population at high risk for diabetes. However, it was brought to our attention that such intervention should be as much as possible individualy oriented, considering many personal and social characteristics of an individual.
The perception of obesity among people has not changed significantly regardless numerous public e... more The perception of obesity among people has not changed significantly regardless numerous public educational programs. Reasons for obesity pandemics are numerous and complex, but can be mostly resumed to life-style changes. The aim of this research was to determine connection between socioeconomic factors and obesity with children of our region. Study included pupils aged 7-8 from 19 first grades in 8 primary schools in Osijek-Baranya County. Body height and weight were measured and socioeconomic data status were collected. Socioeconomic status included data on marital status, educational level, employment, number of children in the family, kindergarten attendance and urban/rural location and also smoking habits of parents. BMI was calculated as a parameter for obesity assessment according to Croatian reference values. Total of 372 children were measured. There were 6.5% of overweight children (BMI between 90th and 97th percentile) and 2.4% of obese children (BMI above 97th percentile). The prevalence of obese children in our research was 8.9%. Obesity is not influenced by rural/urban residence, marital status of parents, number of children in the family, mother's education, or by parents' smoking habits. Positive correlation between obesity and father's education and parents' unemployment was found. Available literature data, same as our study, did not show consistent association between socioeconomic factors and obesity with children. Contradictory results of different studies can be a result of a small sample, difference in study design and different criteria for defining categories within investigated socioeconomic factor.
Numerous studies suggested that sex-hormones could influence cognitive function in women, in life... more Numerous studies suggested that sex-hormones could influence cognitive function in women, in lifetime, but inconsistency in their impact during different phases of menstrual cycle (1-3). In addition, results on the role of progesterone are scarce (4). Here we addressed several methodological problems recognized in published studies: a) inappropriate selection of cycle phases, b) a large inter-individual variability in cognitive function, due to non-homogenous groups of subjects which could affect the reliability of results’ interpretation ; and c) measurement of sex hormones concentrations in blood with standardized tests (5). The aim of this study was to exactly determine the phase of cycle and to evaluate the role of sex hormones in modulation of specific cognitive function. Sixteen healthy, normal cycling female medical students aged 22-24 (M = 23 SD = 0.85) volunteered to participate in this study. The study was approved by the Ethical Committee of the Medical School Osijek, Croatia.Cognitive tasks were performed in three different phases of menstrual cycle (EF - early follicular phase, day 2-4 ; O - proven ovulatory phase and ML – mid-luteal phase, 7 – 9 days after ovulation). To appoint the date of ovulation ELISA-based LH urinary strips were used. Hormone levels (E2 - estrogen, P-progesterone, LH and FSH) were assessed from venous blood to confirm menstrual cycle phases. Values are presented as means±SEM, compared by One way ANOVA repeated measures, post hoc Tukey and Holm-Sidac tests, when appropriate (SigmaStat 3.5). Interestingly, all tested women showed above average results in performed tasks for cognitive function evaluation, independently of type of test. The results of hormone levels have shown that the cognitive tasks were done at appropriate points of menstrual cycle. LH and E2 were highest in O phase ; the highest P level in ML phase of cycle (Table 1). There was no significant difference in immediate and delayed recall, implicate or explicate memory and verbal fluency among any phases of menstrual cycle. However, there was significantly better performance in attention task (given as total score) in ML phase (580.38±15.23) compared to the EF (519±19.19) and the O (547.13±16.35) phase of the cycle (p=0.001), with highest P levels, suggesting that attention task performance could be influenced by progesterone. The results in attention task are not related to the changes in E2 levels. Furthermore, there is no enough valid proof for the role of E2 in the modification of cognitive function in women over the length of cycle.
Timovi obiteljske medicine i patronažne sestre u okviru Doma zdravlja Osijek jos od 1996. god. ko... more Timovi obiteljske medicine i patronažne sestre u okviru Doma zdravlja Osijek jos od 1996. god. kontinuirano provode program mjera zdravstvenog odgoja dijabetickih bolesnika, s ciljem postizanja bolje kontrole te bolesti, koja u Osjecko- baranjskoj županiji konstantno pokazuje visoku zastupljenost, vecu od prosjeka za Hrvatsku. Vođeni vlastitim pozitivnim iskustvom, te na osnovu preporuka iz znanstvene literature o tome da zdravstvena edukacija ima jos bolje ucinke u prevenciji, nego u kontroli dijabetesa, pristupili smo izradi i ovoga istraživanja. Naime, analiza zdravstvenog stanja povratnika u naselja Istocne Slavonije, iz kojih je za vrijeme Domovinskog rata izbjeglo stanovnistvo, ucinjena na stratificiranom uzorku od 519 odraslih osoba, je ukazala na veliku zastupljenost dijabetesa i kardiovaskularnih bolesti u toj populacijskoj skupini, cak vecu i od prosjeka za Istocnu Slavoniju i za Hrvatsku. Zbog toga se odmah pristupilo provođenju programa mjera za suzbijanje cinitelja rizi...
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