The Indonesian Journal of Public Health, Mar 30, 2022
Introduction: Hypertension is the cause of 7.5 million deaths, equivalent to 12.8% of total death... more Introduction: Hypertension is the cause of 7.5 million deaths, equivalent to 12.8% of total deaths based on WHO data. Trunyan Village currently has limited access to health services, low public awareness of maintaining personal health and environmental health, and no descriptive or analytical data discussing hypertension prevalence and risk factors. Methods: Therefore, this study aims to determine hypertension prevalence and risk factors in Trunyan Village, Bangli. This study used a cross-sectional design, with the subject selection method using simple random sampling and blood pressure status as a dependent variable. The interview was conducted on 55 people, which used a questionnaire. Result: Data analyzed used the chi-square test, and the relationship between variables was considered significant with a p-value <0.05. The prevalence of hypertension in Trunyan Village is 52.7%, with female dominance (65.5%) and age ≤50 years (52.7%). There is a significant relationship between hypertension and age (p<0.01; PR=3.50), the habit of consuming sweet foods (p=0.02; PR=0.54), and family history of hypertension (p<0.01; PR=1.91). Conclusion: It can be concluded that hypertension has a significant relationship with risk factors for age, habits of consuming sweets foods, and a family history of hypertension. Further research needs to be carried out with a larger sample size to obtain more representative results.
Funding Acknowledgements: Type of funding sources: None. Background: Although current guidelines ... more Funding Acknowledgements: Type of funding sources: None. Background: Although current guidelines recommend the use of direct oral anticoagulants in patients with non-valvular atrial fibrillation (NVAF), the use of vitamin K antagonists (VKA) is still very widespread, especially in low to middle-income countries in Asia. If VKA/Warfarin is used, a target international normalized ratio (INR) range of 2.00-3.00 is recommended. Still, various studies conducted in Asia have found bleeding rates to be higher in this range. Thus, the "sweet spot" of INR targets in the Asian population is still under debate. Purpose: This study aimed to compare bleeding and ischemic outcomes between the lower target INR and the standard target INR in an Asian population. Methods: We conducted a systematic search in Pubmed, ScienceDirect, Cochrane, SinoMed, CNKI, and Wanfang data for studies conducted in East Asian countries comparing the outcome of standard INR targets (2.00-3.00) with lower INR targets in AF patients on VKA/Warfarin medication. The primary endpoints of interest are thromboembolic events and major bleeding. In addition, we performed a sub-analysis based on the lower INR with homogenized range (1.50-2.00) against the standard INR in primary outcomes. Secondary outcomes in this study were ischemic stroke, hemorrhagic stroke, minor bleeding, all-cause mortality, and
Objective: To determine the effect of administration of combination of purple sweet potato (Ipomo... more Objective: To determine the effect of administration of combination of purple sweet potato (Ipomoea Batatas L.) ethanolic extract and ramipril in a rat model of hypertension. Methods: This is an experimental study with a post-test only control group design and is a collaborative study of the effect of giving a combination of ethanol extract of purple sweet potato tuber (Ipomoea batatas L.) and ramipril in a rat model of hypertension. Thirty male Wistar rats were given 2 mL/day of 4% NaCl diet to induce hypertension. The rats were divided into 3 treatment groups, consisting of NaCl 4% 2 mL/day+combination therapy with purple sweet potato tuber ethanol extract 400 mg/kgBW/day and ramipril 1 mg/day, NaCl 4% 2 mL/day+purple sweet potato tuber ethanol extract 400 mg/kgBW/day and NaCl 4% 2 mL/day+ramipril 1 mg/day. At week 5, rat was executed to examine myocardial PDGF-A expression and measure myocardial collagen deposition. All the obtained data were analyzed statistically. Results: Admi...
Revaskularisasi koroner pada pasien dengan gagal jantung seringkali menjadi keputusan yang sulit ... more Revaskularisasi koroner pada pasien dengan gagal jantung seringkali menjadi keputusan yang sulit akibat diperlukannya pertimbangan antara keuntungan dan risiko perioperatif yang lebih besar pada kelompok pasien seperti ini. Sementara itu, angka mortalitas pasca tindakan CABG pada pasien dengan gagal jantung di Pusat Jantung Nasional Harapan Kita (PJNHK) cukup tinggi. Data yg tercatat pada tahun 2006-2008 menunjukkan bahwa 14 dari 85 orang (16,4%) pasien akhirnya meninggal di rumah sakit.1 Apakah revaskularisasi dengan PCI pada penyakit jantung koroner (PJK) dengan EF rendah namun miokardium yang viabel memiliki peranan di PJNHK? Melaui pemaparan kasus ini akan didiskusikan manajemen Sindroma Gagal Jantung yang disebabkan oleh PJK dengan EF buruk menggunakan revaskularisasi PCI pada pasien yang menolak CABG.
Pendahuluan: Kesalahan dalam mengidentifikasi suatu sinkop sebagai bangkitan epileptik merupakan ... more Pendahuluan: Kesalahan dalam mengidentifikasi suatu sinkop sebagai bangkitan epileptik merupakan hal yang tidak jarang terjadi. Pasien mendapatkan manajemen epilepsi namun bangkitan tidak kunjung terkendali. Masalah kardiovaskular harus dipertimbangkan dalam keadaan ini karena keterlambatan identifikasi meningkatkan mortalitas. Kasus: Pasien laki-laki, 26 tahun, mengalami bangkitan onset general motorik tonik klonik yang terjadi lebih dari 20 kali dalam waktu 18 jam dengan durasi 3-5 menit. Diantara kejang pasien sadar baik tanpa adanya periode bingung. Pasien mendapatkan terapi diazepam 10 mg intravena sebanyak 3 kali pemberian namun kejang terus terjadi. Pemeriksaan fisik menunjukkan bradikardia, kardiomegali dengan bising sistolik mitral dan tidak didapatkan defisit neurologis lainnya. Gambaran EKG menunjukkan AV blok derajat 3 dengan gambaran echocardiography dilatasi ventrikel kiri dengan regurgitasi moderat katup mitral. Pemeriksaan CT-scan kepala dan EEG normal. Dilakukan pe...
Ventricular septal defect (VSD) is a congenital heart disease (CHD) which characterized bya hole ... more Ventricular septal defect (VSD) is a congenital heart disease (CHD) which characterized bya hole in the wall that separate between the right and left ventricle. There are several typesof VSD based on its location, which are perimembranous/conoventricular, subpulmonary/conotruncal, supracristal/doubly commited, muscular and atrioventricular canal/inlet. AVSD is one of the most common CHD which occurs in approximately 2-6 of every 1,000live births and accounts for more than 20% of all CHDs. However, the population of VSDpatients with grown up congenital heart disease (GUCH) is still uncertain. We are presentinga rare case of a 19 year old patient with congestive heart failure NYHA functional class IVdue to uncorrected left-to-right shunt supracristal VSD with body mass index of 35.5 kg/m2. He presented in the emergency room with acute decompensated heart failure profileB. Echocardiography revealed decreased left ventricle (LV) systolic function, normal rightventricle (RV) systolic fun...
As more people are living longer with more significant cardiac disease,permanent pacemakers (PPMs... more As more people are living longer with more significant cardiac disease,permanent pacemakers (PPMs) and implantable cardioverter-defibrillators(ICDs) are being inserted more frequently each year. Beginning early in the21st century, there has also been an expansion in the indications for cardiacimplantable electronic devices (CIED, a term which includes PPMs andICDs), and device therapy has become more complex, frequently involvingmultiple leads per patient. In turn, there will be more occasion where thelead removal for these CIED will be necessary.A 6 y.o. patient was incidentally found to have a fractured pacemaker leadduring during routine x-ray for his respiratory tract infection. The pacemakerwas inserted 5 years ago, indicated for the permanent total atrioventricularblock developed after total correction surgery in Tetralogy of Fallot. Thelead fracture was thought to be caused by a phenomenon known as thesubclavian crush syndrome. A transvenous lead extraction in this patientwas...
The Indonesian Journal of Public Health, Mar 30, 2022
Introduction: Hypertension is the cause of 7.5 million deaths, equivalent to 12.8% of total death... more Introduction: Hypertension is the cause of 7.5 million deaths, equivalent to 12.8% of total deaths based on WHO data. Trunyan Village currently has limited access to health services, low public awareness of maintaining personal health and environmental health, and no descriptive or analytical data discussing hypertension prevalence and risk factors. Methods: Therefore, this study aims to determine hypertension prevalence and risk factors in Trunyan Village, Bangli. This study used a cross-sectional design, with the subject selection method using simple random sampling and blood pressure status as a dependent variable. The interview was conducted on 55 people, which used a questionnaire. Result: Data analyzed used the chi-square test, and the relationship between variables was considered significant with a p-value <0.05. The prevalence of hypertension in Trunyan Village is 52.7%, with female dominance (65.5%) and age ≤50 years (52.7%). There is a significant relationship between hypertension and age (p<0.01; PR=3.50), the habit of consuming sweet foods (p=0.02; PR=0.54), and family history of hypertension (p<0.01; PR=1.91). Conclusion: It can be concluded that hypertension has a significant relationship with risk factors for age, habits of consuming sweets foods, and a family history of hypertension. Further research needs to be carried out with a larger sample size to obtain more representative results.
Funding Acknowledgements: Type of funding sources: None. Background: Although current guidelines ... more Funding Acknowledgements: Type of funding sources: None. Background: Although current guidelines recommend the use of direct oral anticoagulants in patients with non-valvular atrial fibrillation (NVAF), the use of vitamin K antagonists (VKA) is still very widespread, especially in low to middle-income countries in Asia. If VKA/Warfarin is used, a target international normalized ratio (INR) range of 2.00-3.00 is recommended. Still, various studies conducted in Asia have found bleeding rates to be higher in this range. Thus, the "sweet spot" of INR targets in the Asian population is still under debate. Purpose: This study aimed to compare bleeding and ischemic outcomes between the lower target INR and the standard target INR in an Asian population. Methods: We conducted a systematic search in Pubmed, ScienceDirect, Cochrane, SinoMed, CNKI, and Wanfang data for studies conducted in East Asian countries comparing the outcome of standard INR targets (2.00-3.00) with lower INR targets in AF patients on VKA/Warfarin medication. The primary endpoints of interest are thromboembolic events and major bleeding. In addition, we performed a sub-analysis based on the lower INR with homogenized range (1.50-2.00) against the standard INR in primary outcomes. Secondary outcomes in this study were ischemic stroke, hemorrhagic stroke, minor bleeding, all-cause mortality, and
Objective: To determine the effect of administration of combination of purple sweet potato (Ipomo... more Objective: To determine the effect of administration of combination of purple sweet potato (Ipomoea Batatas L.) ethanolic extract and ramipril in a rat model of hypertension. Methods: This is an experimental study with a post-test only control group design and is a collaborative study of the effect of giving a combination of ethanol extract of purple sweet potato tuber (Ipomoea batatas L.) and ramipril in a rat model of hypertension. Thirty male Wistar rats were given 2 mL/day of 4% NaCl diet to induce hypertension. The rats were divided into 3 treatment groups, consisting of NaCl 4% 2 mL/day+combination therapy with purple sweet potato tuber ethanol extract 400 mg/kgBW/day and ramipril 1 mg/day, NaCl 4% 2 mL/day+purple sweet potato tuber ethanol extract 400 mg/kgBW/day and NaCl 4% 2 mL/day+ramipril 1 mg/day. At week 5, rat was executed to examine myocardial PDGF-A expression and measure myocardial collagen deposition. All the obtained data were analyzed statistically. Results: Admi...
Revaskularisasi koroner pada pasien dengan gagal jantung seringkali menjadi keputusan yang sulit ... more Revaskularisasi koroner pada pasien dengan gagal jantung seringkali menjadi keputusan yang sulit akibat diperlukannya pertimbangan antara keuntungan dan risiko perioperatif yang lebih besar pada kelompok pasien seperti ini. Sementara itu, angka mortalitas pasca tindakan CABG pada pasien dengan gagal jantung di Pusat Jantung Nasional Harapan Kita (PJNHK) cukup tinggi. Data yg tercatat pada tahun 2006-2008 menunjukkan bahwa 14 dari 85 orang (16,4%) pasien akhirnya meninggal di rumah sakit.1 Apakah revaskularisasi dengan PCI pada penyakit jantung koroner (PJK) dengan EF rendah namun miokardium yang viabel memiliki peranan di PJNHK? Melaui pemaparan kasus ini akan didiskusikan manajemen Sindroma Gagal Jantung yang disebabkan oleh PJK dengan EF buruk menggunakan revaskularisasi PCI pada pasien yang menolak CABG.
Pendahuluan: Kesalahan dalam mengidentifikasi suatu sinkop sebagai bangkitan epileptik merupakan ... more Pendahuluan: Kesalahan dalam mengidentifikasi suatu sinkop sebagai bangkitan epileptik merupakan hal yang tidak jarang terjadi. Pasien mendapatkan manajemen epilepsi namun bangkitan tidak kunjung terkendali. Masalah kardiovaskular harus dipertimbangkan dalam keadaan ini karena keterlambatan identifikasi meningkatkan mortalitas. Kasus: Pasien laki-laki, 26 tahun, mengalami bangkitan onset general motorik tonik klonik yang terjadi lebih dari 20 kali dalam waktu 18 jam dengan durasi 3-5 menit. Diantara kejang pasien sadar baik tanpa adanya periode bingung. Pasien mendapatkan terapi diazepam 10 mg intravena sebanyak 3 kali pemberian namun kejang terus terjadi. Pemeriksaan fisik menunjukkan bradikardia, kardiomegali dengan bising sistolik mitral dan tidak didapatkan defisit neurologis lainnya. Gambaran EKG menunjukkan AV blok derajat 3 dengan gambaran echocardiography dilatasi ventrikel kiri dengan regurgitasi moderat katup mitral. Pemeriksaan CT-scan kepala dan EEG normal. Dilakukan pe...
Ventricular septal defect (VSD) is a congenital heart disease (CHD) which characterized bya hole ... more Ventricular septal defect (VSD) is a congenital heart disease (CHD) which characterized bya hole in the wall that separate between the right and left ventricle. There are several typesof VSD based on its location, which are perimembranous/conoventricular, subpulmonary/conotruncal, supracristal/doubly commited, muscular and atrioventricular canal/inlet. AVSD is one of the most common CHD which occurs in approximately 2-6 of every 1,000live births and accounts for more than 20% of all CHDs. However, the population of VSDpatients with grown up congenital heart disease (GUCH) is still uncertain. We are presentinga rare case of a 19 year old patient with congestive heart failure NYHA functional class IVdue to uncorrected left-to-right shunt supracristal VSD with body mass index of 35.5 kg/m2. He presented in the emergency room with acute decompensated heart failure profileB. Echocardiography revealed decreased left ventricle (LV) systolic function, normal rightventricle (RV) systolic fun...
As more people are living longer with more significant cardiac disease,permanent pacemakers (PPMs... more As more people are living longer with more significant cardiac disease,permanent pacemakers (PPMs) and implantable cardioverter-defibrillators(ICDs) are being inserted more frequently each year. Beginning early in the21st century, there has also been an expansion in the indications for cardiacimplantable electronic devices (CIED, a term which includes PPMs andICDs), and device therapy has become more complex, frequently involvingmultiple leads per patient. In turn, there will be more occasion where thelead removal for these CIED will be necessary.A 6 y.o. patient was incidentally found to have a fractured pacemaker leadduring during routine x-ray for his respiratory tract infection. The pacemakerwas inserted 5 years ago, indicated for the permanent total atrioventricularblock developed after total correction surgery in Tetralogy of Fallot. Thelead fracture was thought to be caused by a phenomenon known as thesubclavian crush syndrome. A transvenous lead extraction in this patientwas...
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