Per Hol

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Attilio Renzulli

Marian Gaspar

University Of Medicine And Pharmacy Timisoara

State University of New York at Buffalo

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Universidad Nacional Autónoma de México

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University of Melbourne

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Papers by Per Hol

Intraoperative angiography leads to graft revision in coronary artery bypass surgery. Commentary

The Annals of Thoracic Surgery, Aug 31, 2004

Intraoperative angiography leads to graft revision in coronary artery bypass http://ats.ctsnetjou... more

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Patient-Reported Outcome After Randomization to On-Pump Versus Off-Pump Coronary Artery Surgery

Background. Clinical experience with off-pump coronary artery bypass surgery raises the question ... more Background. Clinical experience with off-pump coronary artery bypass surgery raises the question of a patient experienced benefit compared with on-pump surgery. This prospective and randomized study compared patient-reported outcome between surgical groups, as change scores at 3 months after surgery and longitudinally as time-averaged change from baseline through the first year after surgery.

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The relationship of the musculocutaneous nerve to the brachial plexus evaluated by MRI

Journal of Clinical Monitoring and Computing, 2015

Axillary plexus blocks (AXB) are widely used for upper limb operations. It is recommend that AXB ... more Axillary plexus blocks (AXB) are widely used for upper limb operations. It is recommend that AXB should be performed using a multiple injection technique. Information about the course and position of the musculocutaneous nerve (MCN) is of relevance for AXB performance. The objective of this study was to examine the position of the MCN and its relationship to the axillary sheath using MRI. 54 patients underwent an AXB with 40 ml of local anaesthetic before MRI examination. The course of the MCN and the position where it left the axillary sheath and perforated the coracobrachial muscle (MCN exit point), in relation to the axillary artery and the block needle insertion point in the axillary fold, were recorded. The MCN was seen clearly in 23, partly in 26, and not identified in five patients at the MCN exit point. The mean distance from the insertion point of the block needle in the axillary fold to the MCN exit point was 36.8 mm (SD = 18.9, range: 0-90.5). In 37 patients the MCN exit point was positioned inside the Q1 quadrant (lateral anterior to the axillary artery) and in 11 patients inside the Q2 quadrant (medial anterior to the axillary artery). There is a wide variability as to where the musculocutaneous nerve (MCN) leaves the axillary sheath. Therefore multiple injection techniques, or the use of a proximally directed catheter, should be appropriate to block the MCN.

Detection of ischemia and new insight into left ventricular physiology by strain Doppler and tissue velocity imaging: Assessment during coronary bypass operation of the beating heart

Journal of the American Society of Echocardiography, Dec 1, 2004

Detection of myocardial ischemia in humans by strain Doppler and tissue velocity imaging was vali... more

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Experimental hepatic radiofrequency ablation using wet electrodes: electrode-to-vessel distance is a significant predictor for delayed portal vein thrombosis

European Radiology, Mar 16, 2006

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Epicardial Ultrasonography: A Potential Method for Intraoperative Quality Assessment of Coronary Bypass Anastomoses?

Background. Intraoperative quality assessment in coronary artery bypass surgery confirms graft pa... more Background. Intraoperative quality assessment in coronary artery bypass surgery confirms graft patency and enables revision of failing grafts. The aim of this study was to evaluate graft quality intraoperatively by epicardial ultrasonography and to compare this technique with transit time flow measurements and intraoperative angiography, and to evaluate the ability of these methods to predict long-term patency as described by follow-up angiography.

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Graft control by transit time flow measurement and intraoperative angiography in coronary artery bypass surgery

The heart surgery forum, 2001

The aim of this study was to compare the relationship between intraoperative transit time flow me... more The aim of this study was to compare the relationship between intraoperative transit time flow measurements and angiographic findings with long-term graft patency in 72 patients who underwent coronary artery bypass surgery. Transit time flow measurements with recording of mean flow and pulsatility indexes were performed after completion of the anastomoses. Coronary angiography was performed on-table while the patients were still in general anesthesia, and then at follow-up three months and 12 months after surgery. Based on angiography, the grafts were graded as type A (fully patent), type B (having more than 50% diameter reduction), or type O (occluded). Of the 67 left internal mammary artery (LIMA) grafts, 51 (76%) were type A on-table, 14 (21%) were type B, and two (3%) were type O. Of the 57 saphenous vein grafts, 49 (86%) were type A, 7 (12%) were type B, and one (2%) was type O. For both LIMA and vein grafts, there were no differences in flow (p = 0.69 and 0.47, respectively) o...

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[Cerebral CT findings in AIDS]

Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række, Jan 10, 1997

A cerebral CT was performed in 82 of 525 AIDS patients, with positive findings in 46 cases. These... more A cerebral CT was performed in 82 of 525 AIDS patients, with positive findings in 46 cases. These findings included cerebral atrophy in 28 cases, pathological demyelinisation in two, progressive multifocal leukoencephalopathy in one, toxoplasmosis in 11, lymphomas in seven, infarction in one and one subdural haematoma. The radiological findings are correlated to pathology and clinical symptoms. The authors point out the importance of these findings for correct interpretation of the CT scans.

Localized internal radiotherapy with 90Y particles embedded in a new thermosetting alginate gel: A feasibility study in pigs

Nuclear Medicine Communications, 2006

Internal radiotherapy requires the localization of the radionuclide to the site of action. A new ... more Internal radiotherapy requires the localization of the radionuclide to the site of action. A new injectable alginate gel formulation intended to undergo immediate gelation in tissues and capable of encapsulating radioactive particles containing 90Y was investigated. The formulation was injected intramuscularly, into the bone marrow compartment of the femur and intravenously, respectively, in pigs. The distribution of radioactivity in various tissues was determined. Following intramuscular injection, more than 90% of the radioactivity was found at the site of injection. Following injection into bone marrow, 30-40% of the radioactivity was retained at the site of injection, but a considerable amount of radioactivity was also detected in the lungs (35-45%) and the liver (5-18%). Following intravenous injection, 80-90% of the radioactivity was found in the lungs. The present formulation appears suitable for localized radiotherapy in organs and tissues having low perfusion.

Enhanced Nutrient Supply to Very Low Birth Weight Infants is Associated with Improved White Matter Maturation and Head Growth

by Per Hol and A. Ronnestad

Neonatology, 2015

ity, head circumference growth and decreased mean diffusivity (MD) in cerebral white matter (WM) ... more ity, head circumference growth and decreased mean diffusivity (MD) in cerebral white matter (WM) areas, suggesting improved cerebral maturation among infants on the enhanced nutrient supply. Methods: In this randomized controlled trial, infants on the enhanced nutrient supply received increased amounts of energy, protein, fat, essential fatty acids and vitamin A until discharge. DTI was performed close to term equivalent age. Outcomes were growth velocity, head circumference growth and WM mean diffusivity. Results: Among the 50 included infants, 14 in the intervention group and 11 controls underwent a successful DTI. Infants on the enhanced diet achieved improved growth velocity (16.5 vs. 13.8 g/kg/day, p = 0.01) and increased head circumference (Δz score: 0.24 vs. -0.12, p = 0.15). A significantly lower MD was seen in a large WM area such as the superior longitudinal fasciculi (1.19 × 10 -3 vs. 1.24 × 10 -3 mm 2 /s,

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Lingaas PS, Hol PK, Lundblad R, Rein KA, Mathisen L, Smith H-J, Andersen R, Thaulow E, Tønnessen TI, Svennevig JL, Nitter Hauge S, Fredriksen PM, Andersen M, Fosse E. Clinical and radiologic outcome of off-pump coronary surgery at 12 months follow-up: prospective randomized trial. Ann Thorac Surg...

The Annals of Thoracic Surgery

Intraoperative and intermediate-term angiographic results of coronary artery bypass surgery with Symmetry proximal anastomotic device

Journal of Thoracic and Cardiovascular Surgery, 2004

The objective of this study was to investigate the patency in saphenous vein coronary bypass graf... more

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Changes in cardiac and cognitive function and self-reported outcomes at one year after coronary artery bypass grafting

The Journal of Thoracic and Cardiovascular Surgery, 2010

Objective: Although health status after coronary artery bypass grafting improves at the group lev... more Objective: Although health status after coronary artery bypass grafting improves at the group level, individual outcomes demonstrate variation. We aimed to evaluate relative importances of changes in cardiac and cognitive function and symptom status regarding physical and mental health at 1 year after coronary artery bypass grafting.

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Detection of ischemia and new insight into left ventricular physiology by strain Doppler and tissue velocity imaging: Assessment during coronary bypass operation of the beating heart

Journal of the American Society of Echocardiography, 2004

Detection of myocardial ischemia in humans by strain Doppler and tissue velocity imaging was vali... more

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Magnetic resonance imaging evaluation after implantation of a titanium cervical disc prosthesis: a comparison of 1.5 and 3 Tesla magnet strength

by F. Kolstad and Per Hol

European Spine Journal, 2013

Purpose Cervical disc prostheses induce significant amount of artifact in magnetic resonance imag... more Purpose Cervical disc prostheses induce significant amount of artifact in magnetic resonance imaging which may complicate radiologic follow-up after surgery. The purpose of this study was to investigate as to what extent the artifact, induced by the frequently used Discover Ò cervical disc prosthesis, impedes interpretation of the MR images at operated and adjacent levels in 1.5 and 3 Tesla MR.

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Experimental hepatic radiofrequency ablation using wet electrodes: electrode-to-vessel distance is a significant predictor for delayed portal vein thrombosis

European Radiology, 2006

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Strain Echocardiography and Wall Motion Score Index Predicts Final Infarct Size in Patients With Non-ST-Segment-Elevation Myocardial Infarction

Circulation: Cardiovascular Imaging, 2010

Background-Infarct size is a strong predictor of mortality and major adverse cardiovascular event... more Background-Infarct size is a strong predictor of mortality and major adverse cardiovascular events after myocardial infarction. Acute reperfusion therapy limits infarct size and improves survival, but its use has been confined to patients with ST-segment-elevation myocardial infarction. The purpose of this study was to assess the relationship between echocardiographic parameters of left ventricular (LV) systolic function obtained before revascularization and final infarct size in patients with non-ST-segment-elevation myocardial infarction, as well as the ability of these parameters to identify patients with substantial infarction. Methods and Results-Sixty-one patients with non-ST-segment-elevation myocardial infarction were examined by echocardiography immediately before revascularization, 2.1Ϯ0.6 days after hospitalization. LV systolic function was assessed by ejection fraction, wall motion score index, and circumferential, longitudinal, and radial strain in a 16-segment LV model. Global strain represents average segmental strain values. Infarct size was assessed after 9Ϯ3 months by late-enhancement MRI, as a percentage of total LV myocardial volume. A good correlation was found between infarct size and wall motion score index (rϭ0.74, PϽ0.001) and global longitudinal strain (rϭ0.68, PϽ0.001).

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Continuous cardiac output during off-pump coronary artery bypass surgery: pulse-contour analyses vs pulmonary artery thermodilution

British Journal of Anaesthesia, 2007

Background. No gold standard method exists for monitoring continuous cardiac output (CO). In this... more Background. No gold standard method exists for monitoring continuous cardiac output (CO). In this study, the agreement between the two most frequently used methods, PiCCO pulse-contour analysis (PCCO) and STAT pulmonary artery thermodilution (STAT-CO), was assessed during multiple-vessel off-pump coronary artery bypass (OPCAB) surgery.

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