<p>Recombinant profiles were inferred using a sliding window of 350-2 parameters model usin... more <p>Recombinant profiles were inferred using a sliding window of 350-2 parameters model using SimPlot 3.5.1 software. Referral samples corresponding to the major HIV-1 subtypes, indicated by different colors were included in the analyses.</p
<p>Frequency of HIV-1 positive individuals carrying SDRM distributed according to drug clas... more <p>Frequency of HIV-1 positive individuals carrying SDRM distributed according to drug class, time of infection, gender, sexual practice for men, pregnancy, location, age and subtype in sequences obtained in four VCTs located in metropolitan area of Rio de Janeiro, Brazil.</p
Objetivo: analizar a los predictores del uso inconsistente del preservativo entre personas seropo... more Objetivo: analizar a los predictores del uso inconsistente del preservativo entre personas seropositivas con asociación sexual serodiferentes al virus de la inmunodeficiencia humana. Método: estudio transversal, analítico con muestra consecutiva no probabilística que fue constituida por personas viviendo con el virus de la inmunodeficiencia humana con asociación sexual serodiferente y que estaban en seguimiento clínico de ambulatorio. Los datos fueron recogidos por medio de encuesta individual orientada por cuestionario semiestructurado y fueron analizados con análisis bivariado y regresión logística. Resultados: Se identificó que siete variables fueron independientemente asociadas con el uso inconsistente del preservativo. Escolaridad menor que 11 años de estudio (4,9 [2,4-10,1]), ter múltiples asociaciones (5,0 [1,3-19,6]), usar alcohol (2,1 [1,1-4,4]) u otras drogas (2,8 [1,2-6,3]), no recibir consejo con profesional de salud (2,0 [1,1-3,9]), no tener conocimiento sobre tratamien...
Objectives Potential interactions between feminizing hormone therapy (FHT) and pre-exposure proph... more Objectives Potential interactions between feminizing hormone therapy (FHT) and pre-exposure prophylaxis (PrEP) may be a barrier to PrEP use among transgender women (TGW). We aimed to assess the impact of FHT on PrEP plasma pharmacokinetics (PK) among TGW. Methods This was a PK substudy of the effects of FHT on tenofovir disoproxil fumarate/emtricitabine nested to a trans-specific PrEP demonstration study (NCT03220152). Participants were assigned to receive PrEP only (noFHT) or standardized FHT (sFHT; oestradiol valerate 2–6 mg plus spironolactone 100–300 mg) plus PrEP for 12 weeks, after which they could start any FHT (aFHT). Short- and long-term PK assessment occurred at Weeks 12 and 30–48, respectively (plasma samples prior and 0.5, 1, 2, 4, 6, 8 and 24 h after dose). Non-compartmental PK parameters of tenofovir and emtricitabine were compared as geometric mean ratios (GMRs) between noFHT and PrEP and FHT (sFHT at short-term PK; aFHT at long-term PK) participants. Results No diffe...
Combined antiretroviral therapy is now acknowledged for preventing new HIV infections, besides de... more Combined antiretroviral therapy is now acknowledged for preventing new HIV infections, besides decreasing mortality and morbidity. However, in many Latin America countries the epidemic is still driven by unprotected sexual intercourse. This study aims to describe sexual practices related to HIV/STD and to evaluate factors associated to unprotected sex among men who have sex with women (MSW) and men who have sex with men (MSM) under care at a reference center for HIV in Rio de Janeiro, Brazil. A cross-sectional study, nested in a Brazilian clinical cohort, evaluated the sexual practices of 404 sexually active HIV-positive MSW and men who have MSM. Approximately 30 % of them reported unprotected sexual practices during the 6 months prior to the interview. Most frequent risky practices reported were unprotected vaginal sex among MSW and unprotected receptive anal sex among MSM. Factors increasing the chance of unprotected sexual practices among MSW were the partner&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;#39;s desire of becoming pregnant (OR 2.81; CI 95 %: 1.36-5.95). To have received comments about excessive consumption of alcohol (OR 2.43; CI 95 %: 1.01-5.83), illicit drug use (OR 4.41; CI 95 %: 1.75-11.60) and lived in marital situation (OR 2.10; CI 95 %: 1.09-4.08) were significantly associated with unsafe sexual practices among MSM. The results highlight that health care of men living with HIV, as well as the prevention strategies, must consider the particularities of sexual behavior practiced by people who differ in sexual orientation.
Supplemental Material, sj-pdf-1-std-10.1177_0956462421992157 for Possible risk compensation, atti... more Supplemental Material, sj-pdf-1-std-10.1177_0956462421992157 for Possible risk compensation, attitudes, and beliefs among Brazilian individuals potentially eligible for pre-exposure prophylaxis by Larissa M Villela, Valdiléa G Veloso, Brenda Hoagland, Nilo M Fernandes, Esper G Kallas, Jose V Madruga, Ronaldo I Moreira, Beatriz Grinsztejn and Raquel B De Boni in International Journal of STD & AIDS
Pre-exposure prophylaxis (PrEP) prevents HIV infection among men who have sex with men (MSM) and ... more Pre-exposure prophylaxis (PrEP) prevents HIV infection among men who have sex with men (MSM) and transgender women (TGW) who are the groups that presents the high incidence risk in Brazil. This cross-sectional secondary analysis describes possible risk compensation, attitudes, and beliefs regarding the use of PrEP among 723 MSM and TGW evaluated in the PrEP Brazil study pre-screening phase. Possible risk compensation was reported by 31.6% individuals. In the multivariate model, factors that increased the likelihood of possible risk compensation were: self-referring as white vs. Black (AOR 2.05; CI 1.09, 3.85), perceiving high likelihood of getting HIV in next 12 months (AOR 1.78; CI 1.23, 2.56), being less afraid of HIV infection if using PrEP (AOR 1.93; CI 1.19, 3.14), feeling liberated to have more partners if using PrEP (AOR 2.93; CI 1.92, 4.49), and believing closest friends would use PrEP (AOR 2.51; CI 1.1, 5.71). We found that possible risk compensation was more common among i...
The main objective in this qualitative study was to investigate through narratives the simbolic a... more The main objective in this qualitative study was to investigate through narratives the simbolic and imaginarian constructions of volunteers willing to participate in HIV vaccine trial. The database of Projeto Praca Onze, a HIV seroincidence study for a future vaccine trial, that took place in Rio de Janeiro from 1995 and 1998 was used. The Praca Onze was located in downtown of Rio de Janeiro at the Hospital Escola Sao Francisco de Assis, an university hospital of the Federal University of Rio de Janeiro. The target population of this project consisted of men who had sex with men. The methodology used in the research was the oral history interview, which emphasizes the speech as an important and revealing resource not only of subjectivity but also of the world visions inserted in their historic, social, economic and cultural conditions. The analysis and interpretation of the data shall be built from the theoretical issues of the analysis recommended by Carlo Ginzburg (1995). The inte...
The objective of this study was to identify the factors associated with the non-disclosure of HIV... more The objective of this study was to identify the factors associated with the non-disclosure of HIV seropositivity among people living with HIV/AIDS undergoing antiretroviral treatment. A cross-sectional study was carried out in five HIV clinics in the interior of the state of São Paulo, Brazil. Logistic regression analysis was used to determine independent predictors of HIV status disclosure. It was found that 68.5% revealed their HIV seropositivity to their most recent sexual partner. The variables “casual partner” [OR 19.08, 95% CI (4.08, 20.23), p = 0.001], “sexual partners with negative HIV or unknown HIV” [OR 4.54, 95% CI (1.58, 1.01), p = 0.005], “multiple sexual partners” [OR = 3.17, 95% CI (1.34, 7.35), p = 0.009], and “lack of communication with the partner on HIV prevention”[OR = 8.3, 95% CI (3.88, 16.61), p = 0.001] were independently associated with non-disclosure of the diagnosis. Future HIV prevention interventions should encourage open communication between sexual partners.
The ye ar of 1996 showed an important milestone in AIDS treatment due to the advancement of clini... more The ye ar of 1996 showed an important milestone in AIDS treatment due to the advancement of clinical and pharmacological researchs . I n the world appear s a new AIDS treatment, known by Highly Active Antiretroviral Therapy (HAART), which is a treatment scheme that combines several medications to suppress viral replication and the progression of AIDS. The advent of these new drugs expands the therapeutic re sources, improves expectancy and quality of life of people living with HIV and AIDS. This world scenario brings for people living with HIV/AIDS the perspective of having a social life : working, studying, having loving relationships, marry and have children . These relationships can be with people with the same HIV status, defined as seroconcordant or different serology, serodiscordant couples, in which one is infected with HIV or have AIDS and the other not. T opics related to serodiscordant couples, like dis closure to partner, conjugal ity , sexual practices, condom use and re...
BackgroundPre-Exposure Prophylaxis (PrEP) and Post-Exposure Prophylaxis (PEP) are key to preventi... more BackgroundPre-Exposure Prophylaxis (PrEP) and Post-Exposure Prophylaxis (PEP) are key to preventing sexual transmission of HIV, whose sexual partners are at high risk of acquiring HIV.We aimed to determine the factors associated with PrEP and PEP’s knowledge as secondary prevention among people living with HIV/AIDS.MethodCross-sectional analytical study carried out among people living with HIV/AIDS treated at five specialized services in the city of Ribeirão Preto, São Paulo, Brazil. Data were collected from July 2016 to July 2017. Individual interviews were conducted. We used multivariable logistic regression to determine factors associated with knowing PrEP and PEP.ResultsOf the 397 participants, 140 (35.26%) were heterosexual women aged 40 to 49 years (36.2%).Participants with less than 11 years of study (adjusted odds: 0.29; 95% CI: 0.13–0.60); who did not have a low viral load or did not know their viral load (adjusted odds: 0.29; 95% CI: 0.09–0.83) and those with casual partne...
Objective: to analyze predictors of inconsistent condom use among HIV-positive people with sexual... more Objective: to analyze predictors of inconsistent condom use among HIV-positive people with sexual immunodeficiency virus serodifferent sexual partnership. Method: cross-sectional, analytical study with a consecutive non-probabilistic sample consisting of people living with the human immunodeficiency virus with serodifferent sexual partnership and who were in outpatient clinical follow-up. Data were collected through individual interviews guided by a semi-structured questionnaire and subsequently analyzed with bivariate analysis and logistic regression. Results: Seven variables were independently associated with inconsistent condom use. Schooling less than 11 years of schooling (4.9 [2.4-10.1]), having multiple partnerships (5.0 [1.3-19.6]), using alcohol (2.1 [1.1 -4.4]) or other drugs (2.8 [1.2-6.3]), do not receive advice from a healthcare professional (2.0 [1.1-3.9]), have no knowledge of treatment as prevention (3.0 [1,2-6,9]) and not knowing that undetectable viral load reduces...
BACKGROUND Approximately 30% of people living with HIV worldwide are estimated to be unaware of t... more BACKGROUND Approximately 30% of people living with HIV worldwide are estimated to be unaware of their infection. HIV self-testing (HIVST) is a strategy recommended by the World Health Organization which increases access to and uptake of testing among key populations who are at high risk for HIV infection. OBJECTIVE To describe the development and feasibility of a free, anonymous, Internet-based HIV self-testing (HIVST) strategy designed for men who have sex with men (MSM) in Curitiba, Brazil (E-testing). METHODS The project was developed under the scope of the “A Hora é Agora” (Time is now) program. Individuals aiming to request an HIVST package (2 tests each) answered an anonymous 5-minute questionnaire regarding inclusion criteria and sexual risk behavior. Eligible individuals could receive one package every 6 months for free. Website analytics, response to online questionnaires, packages distribution, and return of test results were monitored via a platform-integrated system. RES...
<p>Recombinant profiles were inferred using a sliding window of 350-2 parameters model usin... more <p>Recombinant profiles were inferred using a sliding window of 350-2 parameters model using SimPlot 3.5.1 software. Referral samples corresponding to the major HIV-1 subtypes, indicated by different colors were included in the analyses.</p
<p>Frequency of HIV-1 positive individuals carrying SDRM distributed according to drug clas... more <p>Frequency of HIV-1 positive individuals carrying SDRM distributed according to drug class, time of infection, gender, sexual practice for men, pregnancy, location, age and subtype in sequences obtained in four VCTs located in metropolitan area of Rio de Janeiro, Brazil.</p
Objetivo: analizar a los predictores del uso inconsistente del preservativo entre personas seropo... more Objetivo: analizar a los predictores del uso inconsistente del preservativo entre personas seropositivas con asociación sexual serodiferentes al virus de la inmunodeficiencia humana. Método: estudio transversal, analítico con muestra consecutiva no probabilística que fue constituida por personas viviendo con el virus de la inmunodeficiencia humana con asociación sexual serodiferente y que estaban en seguimiento clínico de ambulatorio. Los datos fueron recogidos por medio de encuesta individual orientada por cuestionario semiestructurado y fueron analizados con análisis bivariado y regresión logística. Resultados: Se identificó que siete variables fueron independientemente asociadas con el uso inconsistente del preservativo. Escolaridad menor que 11 años de estudio (4,9 [2,4-10,1]), ter múltiples asociaciones (5,0 [1,3-19,6]), usar alcohol (2,1 [1,1-4,4]) u otras drogas (2,8 [1,2-6,3]), no recibir consejo con profesional de salud (2,0 [1,1-3,9]), no tener conocimiento sobre tratamien...
Objectives Potential interactions between feminizing hormone therapy (FHT) and pre-exposure proph... more Objectives Potential interactions between feminizing hormone therapy (FHT) and pre-exposure prophylaxis (PrEP) may be a barrier to PrEP use among transgender women (TGW). We aimed to assess the impact of FHT on PrEP plasma pharmacokinetics (PK) among TGW. Methods This was a PK substudy of the effects of FHT on tenofovir disoproxil fumarate/emtricitabine nested to a trans-specific PrEP demonstration study (NCT03220152). Participants were assigned to receive PrEP only (noFHT) or standardized FHT (sFHT; oestradiol valerate 2–6 mg plus spironolactone 100–300 mg) plus PrEP for 12 weeks, after which they could start any FHT (aFHT). Short- and long-term PK assessment occurred at Weeks 12 and 30–48, respectively (plasma samples prior and 0.5, 1, 2, 4, 6, 8 and 24 h after dose). Non-compartmental PK parameters of tenofovir and emtricitabine were compared as geometric mean ratios (GMRs) between noFHT and PrEP and FHT (sFHT at short-term PK; aFHT at long-term PK) participants. Results No diffe...
Combined antiretroviral therapy is now acknowledged for preventing new HIV infections, besides de... more Combined antiretroviral therapy is now acknowledged for preventing new HIV infections, besides decreasing mortality and morbidity. However, in many Latin America countries the epidemic is still driven by unprotected sexual intercourse. This study aims to describe sexual practices related to HIV/STD and to evaluate factors associated to unprotected sex among men who have sex with women (MSW) and men who have sex with men (MSM) under care at a reference center for HIV in Rio de Janeiro, Brazil. A cross-sectional study, nested in a Brazilian clinical cohort, evaluated the sexual practices of 404 sexually active HIV-positive MSW and men who have MSM. Approximately 30 % of them reported unprotected sexual practices during the 6 months prior to the interview. Most frequent risky practices reported were unprotected vaginal sex among MSW and unprotected receptive anal sex among MSM. Factors increasing the chance of unprotected sexual practices among MSW were the partner&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;#39;s desire of becoming pregnant (OR 2.81; CI 95 %: 1.36-5.95). To have received comments about excessive consumption of alcohol (OR 2.43; CI 95 %: 1.01-5.83), illicit drug use (OR 4.41; CI 95 %: 1.75-11.60) and lived in marital situation (OR 2.10; CI 95 %: 1.09-4.08) were significantly associated with unsafe sexual practices among MSM. The results highlight that health care of men living with HIV, as well as the prevention strategies, must consider the particularities of sexual behavior practiced by people who differ in sexual orientation.
Supplemental Material, sj-pdf-1-std-10.1177_0956462421992157 for Possible risk compensation, atti... more Supplemental Material, sj-pdf-1-std-10.1177_0956462421992157 for Possible risk compensation, attitudes, and beliefs among Brazilian individuals potentially eligible for pre-exposure prophylaxis by Larissa M Villela, Valdiléa G Veloso, Brenda Hoagland, Nilo M Fernandes, Esper G Kallas, Jose V Madruga, Ronaldo I Moreira, Beatriz Grinsztejn and Raquel B De Boni in International Journal of STD & AIDS
Pre-exposure prophylaxis (PrEP) prevents HIV infection among men who have sex with men (MSM) and ... more Pre-exposure prophylaxis (PrEP) prevents HIV infection among men who have sex with men (MSM) and transgender women (TGW) who are the groups that presents the high incidence risk in Brazil. This cross-sectional secondary analysis describes possible risk compensation, attitudes, and beliefs regarding the use of PrEP among 723 MSM and TGW evaluated in the PrEP Brazil study pre-screening phase. Possible risk compensation was reported by 31.6% individuals. In the multivariate model, factors that increased the likelihood of possible risk compensation were: self-referring as white vs. Black (AOR 2.05; CI 1.09, 3.85), perceiving high likelihood of getting HIV in next 12 months (AOR 1.78; CI 1.23, 2.56), being less afraid of HIV infection if using PrEP (AOR 1.93; CI 1.19, 3.14), feeling liberated to have more partners if using PrEP (AOR 2.93; CI 1.92, 4.49), and believing closest friends would use PrEP (AOR 2.51; CI 1.1, 5.71). We found that possible risk compensation was more common among i...
The main objective in this qualitative study was to investigate through narratives the simbolic a... more The main objective in this qualitative study was to investigate through narratives the simbolic and imaginarian constructions of volunteers willing to participate in HIV vaccine trial. The database of Projeto Praca Onze, a HIV seroincidence study for a future vaccine trial, that took place in Rio de Janeiro from 1995 and 1998 was used. The Praca Onze was located in downtown of Rio de Janeiro at the Hospital Escola Sao Francisco de Assis, an university hospital of the Federal University of Rio de Janeiro. The target population of this project consisted of men who had sex with men. The methodology used in the research was the oral history interview, which emphasizes the speech as an important and revealing resource not only of subjectivity but also of the world visions inserted in their historic, social, economic and cultural conditions. The analysis and interpretation of the data shall be built from the theoretical issues of the analysis recommended by Carlo Ginzburg (1995). The inte...
The objective of this study was to identify the factors associated with the non-disclosure of HIV... more The objective of this study was to identify the factors associated with the non-disclosure of HIV seropositivity among people living with HIV/AIDS undergoing antiretroviral treatment. A cross-sectional study was carried out in five HIV clinics in the interior of the state of São Paulo, Brazil. Logistic regression analysis was used to determine independent predictors of HIV status disclosure. It was found that 68.5% revealed their HIV seropositivity to their most recent sexual partner. The variables “casual partner” [OR 19.08, 95% CI (4.08, 20.23), p = 0.001], “sexual partners with negative HIV or unknown HIV” [OR 4.54, 95% CI (1.58, 1.01), p = 0.005], “multiple sexual partners” [OR = 3.17, 95% CI (1.34, 7.35), p = 0.009], and “lack of communication with the partner on HIV prevention”[OR = 8.3, 95% CI (3.88, 16.61), p = 0.001] were independently associated with non-disclosure of the diagnosis. Future HIV prevention interventions should encourage open communication between sexual partners.
The ye ar of 1996 showed an important milestone in AIDS treatment due to the advancement of clini... more The ye ar of 1996 showed an important milestone in AIDS treatment due to the advancement of clinical and pharmacological researchs . I n the world appear s a new AIDS treatment, known by Highly Active Antiretroviral Therapy (HAART), which is a treatment scheme that combines several medications to suppress viral replication and the progression of AIDS. The advent of these new drugs expands the therapeutic re sources, improves expectancy and quality of life of people living with HIV and AIDS. This world scenario brings for people living with HIV/AIDS the perspective of having a social life : working, studying, having loving relationships, marry and have children . These relationships can be with people with the same HIV status, defined as seroconcordant or different serology, serodiscordant couples, in which one is infected with HIV or have AIDS and the other not. T opics related to serodiscordant couples, like dis closure to partner, conjugal ity , sexual practices, condom use and re...
BackgroundPre-Exposure Prophylaxis (PrEP) and Post-Exposure Prophylaxis (PEP) are key to preventi... more BackgroundPre-Exposure Prophylaxis (PrEP) and Post-Exposure Prophylaxis (PEP) are key to preventing sexual transmission of HIV, whose sexual partners are at high risk of acquiring HIV.We aimed to determine the factors associated with PrEP and PEP’s knowledge as secondary prevention among people living with HIV/AIDS.MethodCross-sectional analytical study carried out among people living with HIV/AIDS treated at five specialized services in the city of Ribeirão Preto, São Paulo, Brazil. Data were collected from July 2016 to July 2017. Individual interviews were conducted. We used multivariable logistic regression to determine factors associated with knowing PrEP and PEP.ResultsOf the 397 participants, 140 (35.26%) were heterosexual women aged 40 to 49 years (36.2%).Participants with less than 11 years of study (adjusted odds: 0.29; 95% CI: 0.13–0.60); who did not have a low viral load or did not know their viral load (adjusted odds: 0.29; 95% CI: 0.09–0.83) and those with casual partne...
Objective: to analyze predictors of inconsistent condom use among HIV-positive people with sexual... more Objective: to analyze predictors of inconsistent condom use among HIV-positive people with sexual immunodeficiency virus serodifferent sexual partnership. Method: cross-sectional, analytical study with a consecutive non-probabilistic sample consisting of people living with the human immunodeficiency virus with serodifferent sexual partnership and who were in outpatient clinical follow-up. Data were collected through individual interviews guided by a semi-structured questionnaire and subsequently analyzed with bivariate analysis and logistic regression. Results: Seven variables were independently associated with inconsistent condom use. Schooling less than 11 years of schooling (4.9 [2.4-10.1]), having multiple partnerships (5.0 [1.3-19.6]), using alcohol (2.1 [1.1 -4.4]) or other drugs (2.8 [1.2-6.3]), do not receive advice from a healthcare professional (2.0 [1.1-3.9]), have no knowledge of treatment as prevention (3.0 [1,2-6,9]) and not knowing that undetectable viral load reduces...
BACKGROUND Approximately 30% of people living with HIV worldwide are estimated to be unaware of t... more BACKGROUND Approximately 30% of people living with HIV worldwide are estimated to be unaware of their infection. HIV self-testing (HIVST) is a strategy recommended by the World Health Organization which increases access to and uptake of testing among key populations who are at high risk for HIV infection. OBJECTIVE To describe the development and feasibility of a free, anonymous, Internet-based HIV self-testing (HIVST) strategy designed for men who have sex with men (MSM) in Curitiba, Brazil (E-testing). METHODS The project was developed under the scope of the “A Hora é Agora” (Time is now) program. Individuals aiming to request an HIVST package (2 tests each) answered an anonymous 5-minute questionnaire regarding inclusion criteria and sexual risk behavior. Eligible individuals could receive one package every 6 months for free. Website analytics, response to online questionnaires, packages distribution, and return of test results were monitored via a platform-integrated system. RES...
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