Papers by Noralhuda Alabid
Indonesian Journal of Electrical Engineering and Computer Science
The COVID-19 pandemic announced by the World Health Organization has disrupted human lives at dif... more The COVID-19 pandemic announced by the World Health Organization has disrupted human lives at different scales, including the economy, public health, and people's emotions. Social media databases record huge accumulated information concern this pandemic. Twitter platform is considered one of the most active social media that enable users to tweet in different conversations they are concerned about. The problem arises when tweeters want to search about a specific topic. They can only sort tweets by its recency to understand conversation and not by relevancy. This makes tweeters read through the most tweets to understand what was firstly discussed about the related topic. Some strategies were developed for summarizing tweets but summarizing topics of COVID-19 are still at the beginning. The current research aims to introduce a technique to present a short summary related COVID-19 topics with consuming little time and effort. Thus, summarization task started by clustering topics ba...
Conventional usability measurement methods for measuring web applications are costly, sometimes t... more Conventional usability measurement methods for measuring web applications are costly, sometimes time-consuming, and may require professionals. The frameworks, methods, approaches, and tools in which web applications are designed can fully support these limitations. The main issue is to speed up the evaluation process of websites in an effortless manner. To overcome this limitation, this paper proposes an instrument that can use for measuring the usability of web applications (IMUW-APP). A systematic literature review was utilized to determine the instrument dimensions and their items. The validity and reliability test were conducted via face and content validity, goodness testing, and pilot study. Cronbach's Alpha, factor loading, Kaiser-Meyer-Olkin, and Barlett's test were +calculated to ensure the validity and reliability of the proposed instrument. In the light of our analyses, the obtained findings indicate that the proposed instrument (IMUWAPP) is workable and can adapt. Besides, a case study is used to verify the proposed instrument to evaluate a university website. The collecting data have been analyzed and visualized. Ultimately, the overall findings have highlighted.
Indonesian Journal of Electrical Engineering and Computer Science, 2021
A real threat to the people of the world has appeared as a result of the spread of the Coronaviru... more A real threat to the people of the world has appeared as a result of the spread of the Coronavirus disease of 2019 (COVID-19) disease. A lot of scientific and financial support has been made to devote vaccines capable of ending this epidemic. However, these vaccines have become a subject of debate between individuals, as some people tend to support taking vaccines and others rejecting them. This paper aims to create a framework model to classify the sentiment and opinions of individuals that published in Twitter regarding the COVID-19 vaccines. Identify those opinions can help public health institutions to know public opinions and direct their efforts towards promoting taking vaccinations. Two of the machines learning classification models which are the support vector machine (SVM) and naive Bayes (NB) classifier are applied here. Other pre-processing methods were applied as well to filter unstructured tweets.
Molecular Biology Reports, 2020
Genetic polymorphisms of genes whose products are responsible for activities, such as xenobiotic ... more Genetic polymorphisms of genes whose products are responsible for activities, such as xenobiotic metabolism, mutagen detoxification and DNA-repair, have been predicted to be associated with the risk of developing lung cancer (LC). The association of LC with tobacco smoking has been extensively investigated, but no studies have focused on the Arab ethnicity. Previously, we examined the association between genetic polymorphisms among Phase I and Phase II metabolism genes and the risk of LC. Here, we extend the data by examining the correlation of OGG1 Ser326Cys combined with CYP1A1 (Ile462Val and MspI) and GSTP1 (Ile105Val and Ala103Val) polymorphisms with the risk of LC. Polymerase chain reactionrestriction fragment length polymorphism (PCR-RFLP) and gene sequencing were carried out for genotyping the OGG1 polymorphisms of 123 LC patients and 129 controls. No significant differences in the frequencies of the OGG1 mutant allele between patients and controls were found. The distributions of heterozygous Ser/Cys or Cys/Cys genotypes of OGG1 were not associated with the risk of LC either according to the histological types of LC or based on waterpipe tobacco (WP) smoking status. In contrast, the combined effect of OGG1 variants with CYP1A1 and GSTP1 variants revealed a significant correlation with the OGG1 Ser326Cys-CYP1A1 MspI variants pairing. This association was significant (p = 0.001) in individuals who carried homozygous or heterozygous variant type genotypes of both genes in a reference with carriers of both wild-type genotypes (wt/wt − wt/wt). The odds ratios were 2.99 (95% CI 1.67-5.36), 2.68 (95% CI 1.08-6.62), and 2.80 (95% CI 1.18-6.69) for those who carried (wt/wt − wt/vt + vt/vt), (wt/vt + vt/vt − wt/wt), and (wt/vt + vt/vt − wt/vt + vt/ vt), respectively. The study suggests a limited correlation is present between carrying OGG1 Ser326Cys polymorphism and the risk of developing LC in Arab populations.
Correlation of GSTP1 gene variants of male Iraqi waterpipe (Hookah) tobacco smokers and the risk of lung cancer
Molecular Biology Reports, 2020
Glutathione- S -transferases (GSTs) play a role in the detoxification of environmental chemicals ... more Glutathione- S -transferases (GSTs) play a role in the detoxification of environmental chemicals and mutagens, such as those inhaled during tobacco smoking. There have been conflicting reports concerning GST polymorphisms as risk factors in the development of lung cancer. No studies focused on Arab populations exposed to Waterpipe (WP) tobacco smoke have been undertaken. Here Polymerase Chain Reaction-Restriction Fragment Length Polymorphism (PCR-RFLP) and gene sequencing were applied to analyze allelic variations in GSTP1 -rs1695 and -rs1138272 amongst 123 lung cancer patients and 129 controls. The data suggest that WP smoking raised the risk of lung cancer more than three-fold (OR 3.6; 95% CI 2.1–6.0; p < 0.0001). However, there was no significant association between individual GSTP1 polymorphisms and the risk of lung cancer. In contrast, analysis of the rs1695 and rs1138272 combination suggested that the risk of lung cancer was raised more than two-fold for carriers of the GSTP1 -rs1695 (G) allele (OR 2.5; 95% CI 1.0–6.4; p < 0.05), however, the presence of the GSTP1 -rs1138272 (T) allele, in addition to GSTP1 -rs1695, did not significantly change the risk ratio (OR 2.8; 95% CI 1.4–5.7; p < 0.004). WP tobacco smokers who carried the GSTP1 -rs1695, but not GSTP1 -rs1138272, allele were similarly susceptible to lung cancer (OR 2.4; 95% CI 1.1–5.3; p < 0.03). Hence, the results suggest that smoking WP tobacco and carrying GSTP1 -rs1695 polymorphisms are risk factors for lung cancer in Arab Iraqi males.
Egyptian Journal of Medical Human Genetics, 2020
Background STAG3 is the meiotic component of cohesin and a member of the Cancer Testis Antigen (C... more Background STAG3 is the meiotic component of cohesin and a member of the Cancer Testis Antigen (CTA) family. This gene has been found to be overexpressed in many types of cancer, and recently, its variants have been implicated in other disorders and many human diseases. Therefore, this study aimed to analyze the major variants of STAG3. Western blot (WB) and immunoprecipitation (IP) assays were performed using two different anti-STAG3 antibodies that targeted the relevant protein in MCF-7, T-47D, MDA-MB-468, and MDA-MB-231 breast cancer cells with Jurkat and MCF-10A cells as positive and negative controls, respectively. In silico analyses were searched to study the major isoforms. Results WB and IP assays revealed two abundant polypeptides < 191 kDa and ~ 75 kDa in size. Specific bioinformatics tools successfully determined the three-dimensional (3-D) structure, the subcellular localization, and the secondary structures of the isoforms. Furthermore, some of the physicochemical pr...
Meta Gene, 2019
Background: Previous studies about the correlation of genetic polymorphisms in the multigene fami... more Background: Previous studies about the correlation of genetic polymorphisms in the multigene family of cytochrome P450 (CYPs), the effect of tobacco smoking, and the risk of developing cancer have been well investigated in different populations, but not in Iraq. Furthermore, the studies of malignance occurrence relationship with cigarette tobacco smoking revealed the presence of strong association, however, little is known about the risk of Waterpipe (WP) tobacco smoking. Thus, determination two important genetic polymorphisms in CYP1A1, a main member of CYPs, among Iraqi men was our first aim. This is the first study that highlights the correlation of CYP1A1 polymorphisms with the risk of lung cancer in Iraq. The second aim was to evaluate the combined association of WP tobacco smoking and CYP1A1-Ile 462 Val and-MspI polymorphisms in lung cancer risk. Methods: This study included 123 lung cancer patients and 129 controls. To determine the variant genotypes, the techniques of Polymerase Chain Reaction-Restriction Fragment Length Polymorphism (PCR-RFLP) and DNA sequencing were carried out. Results: The data revealed the possible associations of variant (G) allele of CYP1A1-Ile 462 Val (OR = 1.6; 95% CI = 1.1-2.4; P = 0.01) and variant (C) allele of CYP1A1-MspI (OR = 1.9; 95% CI = 1.3-2.7; P < 0.01) with the risk of lung cancer. The variant genotypes of CYP1A1 polymorphisms were significantly correlated in the case of squamous cell carcinoma and synergistically associated in the case of combined effect with WP tobacco smoking (OR Ile 462 Val = 2.0; 95% CI = 1.0-4.1; P = 0.04, and OR MspI = 2.6; 95% CI = 1.3-5.5; P ≤ 0.01). Conclusion: The results suggest that WP tobacco smoking and genetic polymorphisms in CYP1A1 are most likely important risk factors for lung cancer in the Iraqi population.
ECTI Transactions on Computer and Information Technology (ECTI-CIT), 2021
By interpreting spatial relations among objects, many applications such as video surveillance, ro... more By interpreting spatial relations among objects, many applications such as video surveillance, robotics, and scene understanding systems can be utilized efficiently for different purposes. The vast majority of known models for spatial relationships are carried out with an image. However, due to the advance in technology, a three-dimensional scene became available. For our knowledge, most of the interpreted spatial relations were defined between silent objects in images. A technique for determining the dynamic spatial relation between a moving object and another silent one in a time varying scene is presented here. The spatial relationships were determined by using motion-based object tracking along with hypergraph object-oriented model. Defining the spatial relationship types between a single silent object and a moving human body has applied based on two strategies; determining each object with a bounding box, then comparing the locations of these boxes by applying certain condition...
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Papers by Noralhuda Alabid