Mustafa Ergün

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Andrej Dujella

University of Zagreb

Hemin Koyi

Uppsala University

Jana Javornik

University of East London

Graham Martin

University of Leicester

Gwen Robbins Schug

University of North Carolina at Greensboro

Gabriel Gutierrez-Alonso

University of Salamanca

John Sutton

Macquarie University

Eros Carvalho

Universidade Federal do Rio Grande do Sul

Kevin Arbuckle

Swansea University

Jesper Hoffmeyer

University of Copenhagen

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Rating pressure factors affecting logistics systems during the pandemic and the ideal logistic decision selection under the Pythagorean fuzzy environment

Kybernetes

PurposeDue to the current pandemic, the importance of logistics functions and decisions is well u... more PurposeDue to the current pandemic, the importance of logistics functions and decisions is well understood both at the level of companies and users. Logistics systems and related decisions are of vital importance in making supply chains effective, efficient and without disruption. Logistic pressure factors may emerge at different points along the logistics process, and given the role of logistics decisions as one of the important indicators of competitiveness, the determination of the logistics pressures that are likely to increase the costs of business, and their causative factors are a vital aspect of the logistics decision-making process. The study aims to provide assistance in the selection of the most ideal logistics decision by ranking the pressure factors affecting the logistics system, especially during the pandemic period for logistics enterprises operating in Ordu and Giresun provinces and which have a corporate identity.Design/methodology/approachIn this study, it is aime...

Optimum weight design of steel truss roof systems considering corrosion effect

Structures

Resveratrol Supplementation Attenuates Excessive Inflammation and Helps Restore Impaired Restitution in an Intestinal Epithelial Cell Culture Model

The Journal of Pediatric Research

Sustained release of inflammatory mediators, excessive inflammatory response and impaired intesti... more Sustained release of inflammatory mediators, excessive inflammatory response and impaired intestinal epithelial restitution are wellknown mechanisms in the pathogenesis of necrotizing enterocolitis. This study focused on the effect of resveratrol on these pathways. Materials and Methods: In this study, the rat crypt intestinal cell line (IEC-6) culture, an application of lipopolysaccharide or a cytokine mixture and a scratch migration assay model were used. Nitric oxide synthase-2 (iNOS) and cyclooxygenase-2 (COX-2), focal adhesion kinase (FAK) and its phosphorylated form (pFAK) levels were assessed. Results: IEC-6 cells covered 88% of the denuded area in the control, 54% in LPS, and 35% in cytomix groups at the 24 th hour. The treatment with resveratrol at doses of 0.5, 1 and 5 µM/L before LPS resulted in the repair of 84%, 87% and 76% of the denuded areas, respectively. Likewise, with cytomix, it was 86%, 82%, and 78%. Resveratrol at a dose of 5 µM/L prevented an increase in iNOS levels. All three doses of resveratrol were effective in preventing increases in COX levels. FAK or pFAK expressions remained unchanged in all groups. Conclusion: Resveratrol, being known for its antioxidant features, suppresses excessive inflammatory response and helps preservation of mucosal integrity by conservation of epithelial restitution.

Mustafa Ergün

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