Papers by Mozaffar Hosseininezhad
Clinical Rheumatology, 2009
Cultural adaptation and validation of the Persian version of the Arthritis Measurement Scales 2-S... more Cultural adaptation and validation of the Persian version of the Arthritis Measurement Scales 2-Short Form (AIMS2-SF). The translation and cultural adaptation of the original questionnaire was carried out in accordance with published guidelines. Three hundred and fifty consecutive Persian-speaking patients with rheumatoid arthritis (RA) were asked to complete the AIMS2-SF, the Short Form Health Survey (SF-36), and four visual analog scales (VAS) for pain, joint stiffness, and patient's and physician's global assessment to test convergent validity. In addition, 90 randomly selected patients were asked to complete the questionnaire 48 h later for the second time. Moderate to high correlation were found between the AIMS2-SF and subscales of the SF-36 and VAS for pain, morning stiffness, and patient's and physician's global assessment. Cronbach's alpha coefficient for the Persian AIMS2-SF scales ranged from 0.74 to 0.89. The Persian AIMS2-SF scales showed excellent test-retest reliability with Intraclass Correlation Coefficient ranging from 0.83-0.93 (p < 0.01). The results of the present study showed that the Persian AIMS2-SF has reasonably good convergent validity, internal consistency, and test-retest reliability in patients with RA. It can now be applied in clinical settings and future outcome studies in Iran.
Journal of Shahid Sadoughi University of Medical Sciences, 2019
Introdution: Multiple sclerosis is a chronic disease in the nervous system; It has many problems ... more Introdution: Multiple sclerosis is a chronic disease in the nervous system; It has many problems due to its chronic and promising nature. The treatment of this disease includes medical care and empowerment interventions for symptom management. The purpose of this study was to review the empowerment interventions in these patients. Methods: This study was conducted in a Systematic Reviewperiod from January 2000 to June 2018. On indexing sites “Magiran, PubMed, Google Scholar and Science Direct” searched the key words of Multiple Sclerosis, Chronic Disease, Quality of Life, Self-care, Self-management, Rehabilitation, Empowerment, Psychotherapy, Psychological interventions, Clinical Trials, and Randomized Clinical Trial. Out of 1855 articles found, 33 articles were selected for review. Results: The results of this study showed that empowerment interventions in people with MS can be divided into four categories of self-care, self-management, rehabilitation and psychotherapy intervention...
Background and Aim: Multiple Sclerosis (MS) is among the most prevalent chronic and progressive n... more Background and Aim: Multiple Sclerosis (MS) is among the most prevalent chronic and progressive neurological diseases with high simultaneity. MS is associated with some psychological conditions, such as depression and anxiety. Thus, we examined depression and anxiety in individuals with MS in this review study. Methods and Materials/Patients: We conducted this study using a systematic review method relying on the search from January 2010 to December 2020. Accordingly, we searched the following keywords: "multiple sclerosis, MS, psychiatric issues, psychological disorders, psychological problems, anxiety, mental health, quality of life, and depression" in 4 online databases (PsycNET, PubMed, Scopus, and Magiran). Ultimately, we selected 14 comprehensive papers that quantitatively and qualitatively examined psychiatric disorders in patients with MS. Results: A total of 14 studies were analyzed that included 27106 patients with MS. The results achieved by the analytical studies explained that depression and anxiety are significantly higher in patients with MS, compared with the healthy population. The prevalence of depression and anxiety in MS patients was reported to be heterogeneous. Conclusion: Data related to a large number of patients with MS presented a high prevalence of depression and anxiety in them; however, not separating the symptoms from the disorder can be misleading. Consequently, it is recommended to conduct further research to precisely assess the prevalence of depression and anxiety in these patients. It is required that future studies consider the further use of clinical interviews instead of self-reported questionnaires, using sample selection methods, and providing a complete report of patients' demographic, and clinical information.
PubMed, 2012
Background: Multiple sclerosis (MS) is a neurological disease with fatigue as most prevalent symp... more Background: Multiple sclerosis (MS) is a neurological disease with fatigue as most prevalent symptom. Psychopathological symptoms, physical and mental dysfunctions and body mass abnormalities potentially could deteriorate fatigue. Thus, in this study, we aimed at evaluating the effect of these factors on fatigue severity of MS patients. Methods: In this cross-sectional study, 162 patients with mean age of 34.1 ± 9.4 (16-58 years) were recruited by consecutive sampling. All the patients, after completing demographic information were evaluated using Persian versions of Fatigue Severity Scale (FSS), depression, anxiety and stress scale (DASS-21), and short form Health Survey Questionnaire (SF-36). Results: Correlation analysis showed a significant relationship between fatigue severity and depression, anxiety, stress, physical component summary (PCS) and mental component summary (MCS) (P < 0.01). Findings of path analysis demonstrated that PCS is the only variable which has a direct effect on fatigue severity (β = -0.278, P < 0.05). Moreover, the strongest standard coefficient (β) belonged to cause and effect relationship between MCS and depression (β = -0.691, P < 0.0001). Conclusion: Present study made the role of psychopathological symptoms and physical and mental dysfunctions prominent in exacerbation of fatigue severity. Moreover, we can refer to more sensible effect of physical dysfunction related to life on fatigue.
PubMed, Jan 5, 2017
Background: Stroke is the leading cause of death and functional disability. While there have been... more Background: Stroke is the leading cause of death and functional disability. While there have been major advances regarding the management of stroke, a significant proportion of people are still unaware of stroke-related symptoms and risk factors. This study was performed to assess the awareness of stroke's warning signs and risk factors among a sample of Iranian population. Methods: A total of 649 participants were randomly selected using systematic randomization from the list of telephone numbers obtained from the telephone directory. Demographic characteristics were recorded. Participants were asked to answer questions regarding the awareness about stroke, its warning signs and risk factors. Results: Patients' mean age was 32.0 ± 12.2 years old, and 56.4% were women. Hypertension and history of stroke were major risk factors, and loss of consciousness, vertigo and ataxia were major warning signs of stroke correctly identified by respondents. Multiple linear regressions showed that age (β = 0.277, P < 0.001), academic level of education (β = 6.41, P = 0.01), housewifery (β = 8.9, P < 0.001), jobs related to medical care (β = 13.17, P = 0.016) and previous information about stroke (β = 18.71, P < 0.001) were significant predictors of the overall awareness about stroke. Conclusion: The awareness of people about stroke, its risk factors and warning signs were good in this study. The awareness toward stroke can be associated with factors such as age, academic level of education, job and previous information about stroke. Further studies are recommended to program public multimedia and health education in academies and colleges.
PubMed, Nov 1, 2014
Background: Although studies have demonstrated significant negative relationships between quality... more Background: Although studies have demonstrated significant negative relationships between quality of life (QOL), fatigue, and the most common psychological symptoms (depression, anxiety, stress), the main ambiguity of previous studies on QOL is in the relative importance of these predictors. Also, there is lack of adequate knowledge about the actual contribution of each of them in the prediction of QOL dimensions. Thus, the main objective of this study is to assess the role of fatigue, depression, anxiety, and stress in relation to QOL of multiple sclerosis (MS) patients. Materials and methods: One hundred and sixty-two MS patients completed the questionnaire on demographic variables, and then they were evaluated by the Persian versions of Short-Form Health Survey Questionnaire (SF-36), Fatigue Survey Scale (FSS), and Depression, Anxiety, Stress Scale-21 (DASS-21). Data were analyzed by Pearson correlation coefficient and hierarchical regression. Results: Correlation analysis showed a significant relationship between QOL elements in SF-36 (physical component summary and mental component summary) and depression, fatigue, stress, and anxiety (P < 0.01). Hierarchical regression analysis indicated that among the predictor variables in the final step, fatigue, depression, and anxiety were identified as the physical component summary predictor variables. Anxiety was found to be the most powerful predictor variable amongst all (β = -0.46, P < 0.001). Furthermore, results have shown depression as the only significant mental component summary predictor variable (β = -0.39, P < 0.001). Conclusions: This study has highlighted the role of anxiety, fatigue, and depression in physical dimensions and the role of depression in psychological dimensions of the lives of MS patients. In addition, the findings of this study indirectly suggest that psychological interventions for reducing fatigue, depression, and anxiety can lead to improved QOL of MS patients.
Journal of Shahid Sadoughi University of Medical Sciences, Sep 29, 2021
Introduction: The aim of this study was to compare eating behaviors in the patients with multiple... more Introduction: The aim of this study was to compare eating behaviors in the patients with multiple sclerosis (MS) with recurrence of the disease in the past year and the control group. Methods: This analytical cross-sectional study was a comparison that was performed in the statistical population of two groups of people with MS in Guilan Province in the second half of 2018. The first group consisted of people with MS with a recurrence of the disease in the past year and the second group of people with MS without a history of recurrence of the disease in the past year that were selected by matching the variables of age, sex and duration of the disease. In each of these groups, 104 people were employed as a sample in a targeted method from medical centers in Rasht. In order to collect data demographic information form and Dutch Eating Behaviour Questionnaire were used. Research data were analyzed by independent t-test using SPSS software version 16. Results: The results showed that among patients with MS with a history of recurrence and the control group there was a significant difference (P &amp;amp;amp;amp;amp;lt;0.05) in the variables of emotional eating (t = 3.03, P = 0.01), external stimuli (t=4.49, P=0.01) and inhibition in eating (t =3.81, P=0.01). Conclusion: Inappropriate eating behaviors are one of the factors associated with recurrence and disease attacks in people with MS. Therefore, it is suggested that psychologists and nutritionists consider the role of eating behaviors in these individuals to reduce disease attacks.
International journal of MS care, 2020
Background: Self-management is the most important component in the treatment of chronic diseases,... more Background: Self-management is the most important component in the treatment of chronic diseases, including multiple sclerosis (MS). The Bishop and Frain Multiple Sclerosis Self-Management Scale-Revised (MSSM-R) is one of the valid tools available for self-management assessment. The purpose of this study was to evaluate the psychometric properties of the MSSM-R in Iranian people with MS. Methods: This cross-sectional study was conducted in 2018 in the 1600 people with MS in Guilan Province, Iran. In this study, 250 people were selected by convenience sampling. The reliability of the Persian version of this scale was examined by internal consistency and test-retest methods, and validity evidence was evaluated using confirmatory factor analysis. Results: The MSSM-R had acceptable face and content validity. Confirmatory factor analysis results showed that 24 items on this scale have factor loadings in five subscales. Other results showed the internal consistency, as measured by Cronbach α and test
Neurological Sciences, Sep 26, 2013
Although CDH is a major health care problem encountered in headache clinics, our knowledge about ... more Although CDH is a major health care problem encountered in headache clinics, our knowledge about the epidemiological features of CDH is limited in developing countries. The objective of this study was to survey the frequency and clinical features of chronic daily headache (CDH) and its subtypes among Iranian population presenting to a referral tertiary Headache clinic in a University Hospital. This cross-sectional survey was carried out between September 2011 and March 2012. Data of patients with CDH including their age, sex, educational level, and marital status were recorded using structured face-to-face interview. Subtypes of the CDH were determined by history, physical examination and appropriated laboratory or imaging findings. A total number of 177 cases (32.71%) fulfilled the CDH criteria. The frequency of CDH was higher in 40-49 age groups (n = 54) and among women with a female to male ratio of 2.12/1. Chronic migraine was the most common subtype of CDH in 75 cases (44.4%). Chronic tension-type headache and secondary causes were second and third frequent subtypes of CDH in 27.8 and 20.1% of cases, respectively. Cervicogenic headaches (10.7%) and medication overuse headache (4.1%) were the most common causes of secondary headaches. The present study confirmed previous findings which showed a high prevalence of CDH and chronic migraine in clinic setting, with preponderance for women. In addition, we found the highest prevalence of cervicogenic headaches among secondary causes of CDH.
Journal of Guilan University of Medical Sciences, Apr 15, 2014
International Clinical Neuroscience Journal, Feb 26, 2015
Background and Purpose: Disc herniation leading to radiculopathy is one of the important differen... more Background and Purpose: Disc herniation leading to radiculopathy is one of the important differential diagnosis of low back pain which needs specific medical care. Radiculopathies can be initially diagnosed by history taking and physical examination. However role of other diagnostic methods like Magnetic resonance imaging (MRI) and Electromyography (EMG) in narrowing differential diagnosis is warranted when clinical data are inconsistent or inadequate. In this study we evaluated level of agreements among three methods of radiculopathy diagnosis including EMG, MRI and physical exam. Methods: This study is a comparative cross sectional study on 384 patients which was performed among patients who were referred to electrodiagnosis center for their back pain. Results from 3 questionnaires that filled by neurosurgeon for clinical results, radiologist for MRI findings and neurologist for electrodiagnosis findings were psychometrically analyzed using Kappa index for agreement among three methods. Results: From the 384 cases studied, MRI were successful in 90.6% (348 cases) to identify radiculopathy and EMG and clinic with 76.6% (295 cases) and 70.5% (286 patients), respectively. EMG and MRI have agreed in 76.8% of cases in the diagnosis of radiculopathy. MRI and clinical data in 69.7% of cases (Pvalue<0.940) and EMG and clinical data in 62.7% of cases (Pvalue< 0.843) have agreed but they were not statistically significant. Conclusion: Study results show that MRI is the best diagnostic tool for evaluating the presence of radiculopathy but EMG could also be used instead of MRI in radiculopathy diagnosis. Since EMG is more invasive than MRI, EMG is better to be considered as a second diagnostic tool.
Current Neurovascular Research, Aug 25, 2014
Iron overload may contribute to brain damage that involves delayed brain atrophy, edema, and neur... more Iron overload may contribute to brain damage that involves delayed brain atrophy, edema, and neuronal cell death as well as unfavorable outcome following ischemic stroke and intracerebral hemorrhage (ICH). This prospective study was performed to determine the association of serum ferritin level, an iron storage protein, with perihematoma edema (PHE) growth as well as in-hospital mortality and long-term clinical outcome of patients with ICH. Data was collected from patients with ICH from February 2011 to April 2012. Demographic and clinical data were recorded and serum ferritin was measured on admission. Brain CT scan was performed on admission and 72 hours later. Volume of hematoma and PHE was calculated using ABC/2 formula. Functional outcome was assessed using modified Rankin Scale. A total of 63 patients were included in this study, of those 11 (17.5%) patients died during the first 72 hours of admission. There was a significant correlation between PHE growth during first 72 hours of hospitalization and serum ferritin (P&amp;amp;amp;amp;amp;amp;lt;0.001) as well as history of diabetes mellitus (P&amp;amp;amp;amp;amp;amp;lt;0.001). PHE growth during the first 72-hours of hospitalization and baseline hematoma volume were both predictors of in-hospital mortality and poor outcome (P=0.026 and P=0.035, respectively). These results indicate the role of iron overload in the development of PHE following ICH. However, it seems that serum ferritin level is not directly associated with in-hospital mortality and long-term functional outcome.
Zahedan Journal of Research in Medical Sciences, Nov 1, 2012
Background: Multiple sclerosis (MS) is one of the most frequent and debilitating disease of the n... more Background: Multiple sclerosis (MS) is one of the most frequent and debilitating disease of the nervous system. Some recent studies show the possible role for iron and ferritin in the course of MS. The aim of this study was to evaluate the level of serum iron and ferritin in patients with MS and comparision of them with control group. Materials and Methods: In this descriptive study, serum iron and ferritin were determined in 30 patients with MS and compared with 30 healthy persons, which were matched in terms of age and gender. Data were analyzed with statistical descriptive methods and and t-test4 T. Results: In this study, 30 patients were evaluated. The mean age of both groups was 35.2. Mean serum iron in patients group was 85.16±38.38, and in control group was 91.73±27.89. Mean serum ferritin in patients group was 132.20±80.71 and in control group was 147.40±75.02. There was no significant relationship between serum iron and ferritin in both groups, and also there was no relationship between serum iron and ferritin with age and sex and the type of disease. Conclusion: This study did not show any difference between serum iron and ferritin in patients with multiple sclerosis and control group4 T .4 T
DOAJ (DOAJ: Directory of Open Access Journals), May 1, 2014
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Caspian Journal of Neurological Sciences, 2016
Background: The National Institutes of Health Stroke Scale (NIHSS) can objectively quantify the s... more Background: The National Institutes of Health Stroke Scale (NIHSS) can objectively quantify the severity of stroke. However no information is available about psychometric properties and it's applicability in the Iranian population. Objectives: The present study purposed by utilization of this instrument for neurological deficits measurement due to stroke, to determine the internal consistency reliability and concurrent validity of NIHSS to separate two groups of men and women patients. Materials and Methods: In a cross-sectional study, 206 ischemic stroke patients were selected and the internal consistency reliability and concurrent validity of NIHSS were assessed. For this purpose, Barthel index that measures the functional disability was used. Data also were analyzed by Independent ttest, Chi-square, Pearson correlation, Fisher's z tests and bivariate regression analysis. Results: Internal consistency for men (α=0.881), women (α=0.913) and total patients (α=0.893) was excellent. Negative correlation was found between NIHSS and Barthel index in both men (r=-0.43, p<0.0001) and women (r=-0.63, p<0.0001) and this relationship estimated to be more significant among women rather than men (p<0.05). In addition, NIHSS scores could significantly predict the Barthel score in both groups (p<0.0001) but the results revealed the more ability of NIHSS in predicting functional disability for women (R 2 =0.40) rather than men (R 2 =0.18). Conclusion: Persian version of NIHSS was reliable and valid instrument that can be applicable in both men and women with ischemic stroke; however, it was found that the degree of concurrent validity is better among women than men.
Iranian Journal of Neurosurgery
Background and Aim: Chronic pain is an emotional experience with unpleasant psychological consequ... more Background and Aim: Chronic pain is an emotional experience with unpleasant psychological consequences for individuals and society. This research aims to systematically review the psychological interventions implemented in people suffering from chronic pain. Methods and Materials/Patients: In this systematic review, the following keywords were searched in PubMed, Scopus, and Google Scholar databases: Chronic pain, psychological interventions, psychotherapy, psychology, clinical trials, and randomized clinical trials. The time span for the search was from January 2018 to December 2022. From a total of 2785 articles, 20 articles by 2078 contributors were selected for this review. Results: Cognitive behavioral therapy ranks first among psychological interventions for people with chronic pain. Also, to improve the quality of life and psychological health of these individuals from other psychological interventions, such as acceptance and commitment therapy, the mindfulness method has bee...
تحقیقات علوم رفتاری, Feb 22, 2014
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Papers by Mozaffar Hosseininezhad