Papers by Mohammad Andalibi
International journal of reproductive biomedicine (Yazd, Iran), 2016
Regarding to the recent advances in assisted reproductive techniques (ART), twin and multiple pre... more Regarding to the recent advances in assisted reproductive techniques (ART), twin and multiple pregnancies have increased during past years. This study was performed to compare obstetrics and perinatal outcomes of dichorionic twin pregnancy following ART with spontaneous pregnancy. In this cross-sectional study which was performed in Ghaem Hospital, Mashhad University of Medical Sciences, 107 dichorionic twin pregnancy were enrolled in two groups: spontaneous group (n=96) and ART group (n=31). Basic criteria and obstetrics and neonatal outcomes information including demographic data, gestational age, mode of delivery, pregnancy complications (preeclampsia, gestational diabetes, preterm labor, and intrauterine growth retardation (IUGR), postpartum hemorrhage), neonatal outcomes (weight, first and fifth minute Apgar score, Neonatal Intensive Care Unit (NICU) admission, mortality, respiratory distress, and icterus) were recorded using a questionnaire. Preterm labor, gestational diabetes...
Background: Median sternotomy and resternotomy is the standard technique for coronary artery bypa... more Background: Median sternotomy and resternotomy is the standard technique for coronary artery bypass grafting (CABG), valvular heart disease, and congenital heart disease. Despite advances in many areas of cardiac surgical procedures, there is a lack of innovation in sternal closure techniques. Several studies have examined sternal closure techniques including wiring, interlocking , plate and screw, and bone cementation. However, none of them achieved widespread acceptability. On one hand, serious post-operative complications are associated with the use of wiring and plating techniques in high-risk patients. The aim of this study is showing challenges and difficulties with resternotomy in patient with a history of previous cardiac surgery and usage of biologic bone cements. Case Report: The case was a 56-year-old woman with a history of previous sternotomy for mitral and aortic valve replacement (mechanical sj. No. 29 and mechanical sj. No. 21, respectively) using biologic bone cement (Kryptonite TM, Doctors Research Group Inc.) for her osteopenic sternum. Four years after the mitral valve replacement (MVR), she was referred to emergency department with a thrombosis at the mitral valve. She underwent emergent cardiac surgery with a very difficult resternotomy under femoral cannulation support. Conclusion: Resternotomy in patients with previous sternotomy with Kryptonite bone cements or calcium phosphate cements (CPC) is safe and can be done similar to other cardiac reoperations. It seems that reoperation in this patients does not increase the risk of bleeding, morbidity, and mortality.
The Heart Surgery Forum, 2015
Background: It is common practice for patients with prosthetic cardiac devices, especially heart ... more Background: It is common practice for patients with prosthetic cardiac devices, especially heart valve prosthesis, arterial stents, defibrillators, and pacemaker devices, to use anticoagulation treatment. When these patients suffer from multiple trauma after motor vehicle accidents, the best medi- cal management for this challenging position is mandatory. This strategy should include a rapid diagnosis of all possible multiple organ injuries, with special attention to anticoagula- tion therapy so as to minimize the risk of thromboembolism complication in prosthetic devices. In this review, we describe the best medical management for patients with multiple trauma who use anticoagulants after heart valve replacement. Methods: We searched electronic databases PubMed/ Medline, Scopus, Embase, and Google Scholar using the fol- lowing terms: anticoagulant, warfarin, heparin, and multiple trauma. Also, similar studies suggested by the databases were included. Non-English articles were excluded from the review. Results: For patients who use anticoagulation therapy, teamwork between cardiac surgeons, general surgeons, anes- thesiologists, and cardiologists is essential. For optimal medi- cal management, multiple consults between members of this team is mandatory for rapid diagnosis of all possible damaged organs, with special attention to the central nervous system, chest, and abdominal traumas. With this strategy, it is impor- tant to take note of anticoagulation drugs to minimize the risk of thromboembolism complications in cardiac devices. Conclusion: The best anticoagulant agents for emergency operations in patients with multiple trauma who are using an anticoagulant after heart valve replacement are fresh frozen plasma (FFP) and prothrombin complex concentrates (PCC).
Journal of Biosciences and Medicines, 2015
Background: Median sternotomy and resternotomy is the standard technique for coronary artery bypa... more Background: Median sternotomy and resternotomy is the standard technique for coronary artery bypass grafting (CABG), valvular heart disease, and congenital heart disease. Despite ad-vances in many areas of cardiac surgical procedures, there is a lack of innovation in sternal closure techniques. Several studies have examined sternal closure techniques including wiring, interlocking, plate and screw, and bone cementation. However, none of them achieved widespread acceptability. On one hand, serious post-operative complications are associated with the use of wiring and plating techniques in high-risk patients. The aim of this study is showing challenges and difficulties with resternotomy in patient with a history of previous cardiac surgery and usage of biologic bone cements. Case Report: The case was a 56-year-old woman with a history of previous sternotomy for mitral and aortic valve replacement (mechanical sj. No. 29 and mechanical sj. No. 21, respectively) using biologic bone cement (Kryptonite TM, Doctors Research Group Inc.) for her osteopenic sternum. Four years after the mitral valve replacement (MVR), she was referred to emergency department with a thrombosis at the mitral valve. She under-went emergent cardiac surgery with a very difficult resternotomy under femoral cannulation support. Conclusion: Resternotomy in patients with previous sternotomy with Kryptonite bone cements or calcium phosphate cements (CPC) is safe and can be done similar to other cardiac reoperations. It seems that reoperation in this patients does not increase the risk of bleeding, morbidity, and mortality.
Background: Metabolic syndrome is probably the most common coronary risk factor. Researchers are ... more Background: Metabolic syndrome is probably the most common coronary risk factor. Researchers are not sure whether metabolic syndrome is due to one single cause, but all of the syndrome's risk factors are related to obesity. Objectives: There are few data to look at the association between the features of metabolic syndrome and biochemical markers and dietary intake. Therefore, we wish to investigate the association between number of metabolic syndrome features (from 0 to 5 criteria) and biochemical markers and dietary intakes Methods: This cross-sectional epidemiologic study was conducted among 748 men aged 20-69 years old who were employees of Shahid Hasheminejad Gas Processing Company northeast of Iran. We categorized them into six groups from cases without any criteria to cases with all five criteria which includes zero criteria(n=100,13.4%), one criteria(n=195,26.1%), two criteria(n=198,26.5%), three criteria(n=160,21.4%), four criteria(n=68,9.1%) and five criteria(n=27,3.6%...
International Journal of Public Health, 2015
The Mashhad stroke and heart atherosclerotic disorder (MASHAD) study is a 10-year cohort study th... more The Mashhad stroke and heart atherosclerotic disorder (MASHAD) study is a 10-year cohort study that aims to evaluate the impact of various genetic, environmental, nutritional and psychosocial risk factors on the incidence of cardiovascular events among an urban population in eastern Iran. The MASHAD study comprises a cohort of 9704 individuals aged 35-65 years using a stratified cluster random sampling design. This cohort will be followed up until 2020, with follow-up examinations being undertaken every 3 years. Ten-year cardiovascular disease (CVD) risk estimation was determined using NCEP ATP III criteria. Overall, 88.4 % of women and 79.2 % of men (P < 0.001) had at least one lipid abnormality. The 10-year risk for CVD of <10, 10-20 and >20 % were observed to be 86.6, 11 and 2.5 %, respectively. Predicted risk of CVD > 10 % using the Framingham algorithm was considerably higher in men compared to women. Overall, 9.5 % [95 % confidence interval (CI) 8.9-10.1 %] of our subjects had prevalent CAD. The prevalence of CVD risk factors within our population is high compared to Western countries, indicating the necessity for interventional risk modifications.
The Malaysian journal of medical sciences : MJMS
Patients with long-term complications of sulfur mustard (SM) poisoning are often less able to und... more Patients with long-term complications of sulfur mustard (SM) poisoning are often less able to undertake optimum levels of physical activity and adequately control their dietary intake. The aim of present study was to investigate the dietary intake of patients with SM poisoning in comparison to a control group Methods: The study was undertaken on 55 Iranian male veterans, who had > 25% disabilities due to long-term complications of SM poisoning and 55 men age-matched healthy subjects. A previously validated food frequency questionnaire (FFQ) was used for measuring dietary macro/micro nutrient intake for both groups; and the results were analysed using Dietplan6 software. Analysis of macro/micro nutrients in dietary intakes of the patients versus the controls showed a significantly lower intake of several nutrients including selenium and carbohydrate. On the other hand, the dietary intake of trans-fatty acids and iodine were significantly higher in these patients. Long-term complic...
Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences, 2013
Among the genetics disorders, Down syndrome (DS) is the major cause of mental retardation, congen... more Among the genetics disorders, Down syndrome (DS) is the major cause of mental retardation, congenital heart and intestinal disease. So far, no certain therapeutic method has been suggested for the treatment of this syndrome. The aim of the current survey was to investigate the frequency of parental consanguinity, maternal age in the patients with DS. This study was conducted on 38 consecutive patients with clinically and laboratory confirmed DS who referred to the genetic lab of a referral University Hospital. The G-banding method for karyotyping was employed. The patients were 21 males and 17 females within the age of 16 days to 28 years old. Free trisomy (92.1%, n = 35) was the most common chromosomal abnormality. The frequency of DS was higher among the non-consanguine marriages (71.1%) in comparison with the consanguine marriages (28.9%). Mean age of the mothers in the consanguine marriages (mean = 27.1 ± 6.3) was lower than in the non-consanguine marriages (mean = 31.1 ± 7.7). ...
Clinical Laboratory, 2013
Background: It has been reported that obesity is associated with higher levels of oxidative stres... more Background: It has been reported that obesity is associated with higher levels of oxidative stress. We aimed to evaluate the hypothesis that pro-oxidant antioxidant balance (PAB) values could be affected by adiposity and to assess the association between PAB levels and indices of obesity. Methods: Subjects (n = 733) were recruited and then were divided into 3 groups of normal-weight (BMI ≤ 25, n = 207), overweight (25 < BMI ≤ 30, n = 375), and obese (BMI > 30, n = 151). PAB values were measured in all participants. Results: There was a significant association between PAB values and weight when the correlation was determined for all subjects (p < 0.05). Obese subject had significantly higher levels of PAB values [40.8 (34.3 -51.1) HK unit] compared with overweight [37.5 (29.7 -47.3) HK unit] and normal-weight subjects [37.2 (29.6 -45.2) HK unit] (p < 0.05 in each case). However, there was no significant difference in PAB values between normal and over-weight subjects (p > 0.05). On performing the analysis of covariance, low-density lipoprotein-cholesterol (LDL-C) was found to have a significant independent association with PAB values (β = 0.046, p = 0.04). Conclusions: The high levels of PAB values in obese subjects without overt signs/symptoms of cardiovascular disease may be related to a heightened state of oxidative stress associated with obesity. (Clin. Lab. 2013;59:xx-xx. DOI: 10.7754/Clin.Lab.2012.120403) KEY WORDS pro-oxidant-antioxidant balance, body mass index, obesity, adiposity, oxidative stress
Clinical Biochemistry, 2011
an inverse and significant correlation between HDL and LDL levels. The correlation between choles... more an inverse and significant correlation between HDL and LDL levels. The correlation between cholesterol-triglyceride and high density lipoprotein concentration was also significant and negative.
Clinical Biochemistry, 2011
Processing Company (S.G.P.C) and 3907 males from Mashhad as a representation of its population. C... more Processing Company (S.G.P.C) and 3907 males from Mashhad as a representation of its population. CVD risk factors such as obesity, HTN (systolic blood pressure ≥140 or diastolic blood pressure ≥90 mm Hg), biochemical markers, anxiety (total score ≥8 in Beck's anxiety inventory) and depression symptoms (total score ≥10 in Beck's depression inventory) were assessed.
Clinical Biochemistry, 2011
Background: It has been reported that obesity is associated with higher levels of oxidative stres... more Background: It has been reported that obesity is associated with higher levels of oxidative stress. We aimed to evaluate the hypothesis that pro-oxidant antioxidant balance (PAB) values could be affected by adiposity and to assess the association between PAB levels and indices of obesity. Methods: Subjects (n = 733) were recruited and then were divided into 3 groups of normal-weight (BMI ≤ 25, n = 207), overweight (25 < BMI ≤ 30, n = 375), and obese (BMI > 30, n = 151). PAB values were measured in all participants. Results: There was a significant association between PAB values and weight when the correlation was determined for all subjects (p < 0.05). Obese subject had significantly higher levels of PAB values [40.8 (34.3 -51.1) HK unit] compared with overweight [37.5 (29.7 -47.3) HK unit] and normal-weight subjects [37.2 (29.6 -45.2) HK unit] (p < 0.05 in each case). However, there was no significant difference in PAB values between normal and over-weight subjects (p > 0.05). On performing the analysis of covariance, low-density lipoprotein-cholesterol (LDL-C) was found to have a significant independent association with PAB values (β = 0.046, p = 0.04). Conclusions: The high levels of PAB values in obese subjects without overt signs/symptoms of cardiovascular disease may be related to a heightened state of oxidative stress associated with obesity. (Clin. Lab. 2013;59:xx-xx. DOI: 10.7754/Clin.Lab.2012.120403) KEY WORDS pro-oxidant-antioxidant balance, body mass index, obesity, adiposity, oxidative stress
Clinical Biochemistry, 2011
Introduction: Tuberculosis, caused by Mycobacterium tuberculosis, is a public health problem and ... more Introduction: Tuberculosis, caused by Mycobacterium tuberculosis, is a public health problem and remains a major cause of morbidity and mortality around the world. One third of the earth's population is infected with TB but only 10% individuals infected will develop the disease.This fact indicate that genetic factors play an important role in susceptibility to TB. The purinergic P2X7 receptors shown to induce killing of intracellular M. tuberculosis, followed by apoptosis of the infected macrophage.
Clinical Biochemistry, 2011
Clinical Biochemistry, 2011
lipoprotein (oxLDL) level in healthy and well glycemic controlled type 2 diabetic subjects.
Clinical Biochemistry, 2011
The results of this study showed that giardiasis increases the level of iron and zinc and decreas... more The results of this study showed that giardiasis increases the level of iron and zinc and decreases the level of copper in the sera of patients. These differences were not significant between patients and control individuals.
Annals of Clinical Biochemistry, 2013
Background: Inflammatory states are known to cause an imbalance in the redox status. We aimed to ... more Background: Inflammatory states are known to cause an imbalance in the redox status. We aimed to study the possible associations between pro-oxidant -antioxidant balance (PAB) and serum high-sensitive C-reactive protein (hs-CRP) concentrations and traditional cardiovascular disease (CVD) risk factors in an unselected Iranian population and in groups of individuals with specific disease. Methods: The study was conducted among an unselected population of 758 male subjects. Biochemical markers, including hs-CRP and PAB values, were measured. Results: Serum hs-CRP concentrations were positively associated with serum PAB values (r ¼ 0.260, P 0.001). Univariate analysis showed that PAB values were statistically higher in individuals who were obese or smokers compared with nonobese and non-smokers individuals (P , 0.01). While serum hs-CRP concentrations were significantly higher in older subjects, subjects with obesity, diabetes mellitus, metabolic syndrome, central obesity, hypertriglyceridaemia, higher low-density lipoprotein cholesterol concentrations, positive history of CVD and lower physical activity than subjects without these risk factors (P , 0.05). Comparing hs-CRP and PAB values in different CVD risk score subgroups showed a significant incremental rise in both parameters as CVD risk score increased (P , 0.05). Using multiple linear regression analysis we found a strong association between PAB values and hs-CRP concentrations.
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Papers by Mohammad Andalibi