Papers by Moses Orhero
International …, 2010
Free radicals are well documented for playing a dual role in our body as both deleterious and ben... more Free radicals are well documented for playing a dual role in our body as both deleterious and beneficial species. In low/moderate concentrations free radicals are involved in normal physiological functions but excess production of free radicals or decrease in antioxidant level leads to oxidative stress. It is a harmful process that can be mediates damage to cell structures, including lipids, proteins, RNA and DNA which leads to number of diseases. A variety of synthetic medicine employed in the treatment of different diseases also capable to generate free radicals in body which may causes another disease. The plant sources are rich of antioxidants, phyto-constituents are capable to terminate free radical reactions and prevent our body from oxidative damage. Vegetables and fruits are also important sources of antioxidant substances. Different phytoconstituents and herbal product which are safer then synthetic medicine and beneficial in the treatment of diseases caused by free radicals, it also protect the body by prevent the free radicals to cause tissue injury. Phytoconstituents are conferring less side effect and compatible to body physiology. Therefore it is demand of modern era to use such phytoconstituents or phytomedicines.
ANTIEPILEPTIC EFFECT OF AQEOUS AND ETHANOL LEAF EXTRACTS OF AZADIRACHTA INDICA IN MICE., 2019
The study evaluated the antiepileptic effect of the aqueous and ethanol leaf extracts of Azadirac... more The study evaluated the antiepileptic effect of the aqueous and ethanol leaf extracts of Azadirachta indica on models of maximal electroshock and pentelynetetrazole induced seizure models in mice. The study showed that the extracts were able to abolish and mitigate seizures inced in mice and showed protection mice against seizures and motarlity. The study therefore validates the use of this plant in traditional medicine.
Drafts by Moses Orhero
PREVALENCE AND FACTORS INFLUENCING RELAPSE
AMONG SUBSTANCE ABUSE PATIENTS IN MENTAL
HEALTH REHA... more PREVALENCE AND FACTORS INFLUENCING RELAPSE
AMONG SUBSTANCE ABUSE PATIENTS IN MENTAL
HEALTH REHABILITATION AND RESEARCH
HOSPITAL UYO, AKWA IBOM STATE
By
Orhero Moses*, Ekanem Caroline.
Federal Neuropsychiatric Hospital, Calabar, Cross River, Nigeria.
ABSTRACT
Relapse is a fairly common problem for people recovering from substance abuse or addiction in mental health rehabilitation and research hospital Uyo, Akwa Ibom State. although it is a world-wide issues, motivated by these therefore, this research work was carried out to investigate the prevalence and factors influencing relapse among substance abuse patients in mental health rehabilitation and research hospital, between 2015-2020. The objectives set were; to determine the prevalence of relapse among substance abuse patients in MHRRH, to determine the socio-demographic characteristics of relapse among substance abuse patients
MOSES ORHERO , 2018
This study is aimed at discovering C D K to develop anticancer medicine that could help to add... more This study is aimed at discovering C D K to develop anticancer medicine that could help to address cancer and tumur cells resistance.
Targeted drugs
1. T y r o s i n e. p r o t e i n. k i n a s e. i n h i b i t o r s : Ni l o t i n i b , I ma t i n i b.
2. E G F r e c e p t o r i n h i b i t o r s : G e f i t i n i b , E r l o t i n i b , C e t u x i ma b.
3. A n g i o g e n e s i s. i n h i b i t o r s :
B e v a c i z u ma b , S u n i t i n i b.
4. P r o t e a s o me. i n h i b i t o r : B o r t e z o mi b
Thesis Chapters by Moses Orhero
ANTIEPILEPTIC EFFECT OF AQUEOUS AND ETHANOL LEAF EXTRACTS OF Azadirachta indica IN MICE ANTIEPILEPTIC EFFECT OF AQUEOUS AND ETHANOL LEAF EXTRACTS OF Azadirachta indica ON MAXIMAL ELECTROSHOCK AND PENTYLENETETRAZOLE INDUCED SEIZURES IN MICE , 2019
This study evaluated the antiepileptic effect of aqueous and ethanol leaf extracts of Azadirachta... more This study evaluated the antiepileptic effect of aqueous and ethanol leaf extracts of Azadirachta Indica (commonly known as dongoyaro) on models of maximal electroshock (MES) and pentylentetrazole (PTZ) induced seizures in mice. The study showed that the extracts were able to abolish and mitigate the seizures induced in mice and protected the mice from mortality.
The study therefore justifies the medicinal properties of Azadirachta indica as utilized in traditional medicine.
ORHERO MOSES , 2018
The aim of the study was to determine the prevalence of tramadol abuse patient in Nigeria between... more The aim of the study was to determine the prevalence of tramadol abuse patient in Nigeria between 2013 to 2018 and identify factors responsible for Tramadol Abuse among the youth.
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Papers by Moses Orhero
Drafts by Moses Orhero
AMONG SUBSTANCE ABUSE PATIENTS IN MENTAL
HEALTH REHABILITATION AND RESEARCH
HOSPITAL UYO, AKWA IBOM STATE
By
Orhero Moses*, Ekanem Caroline.
Federal Neuropsychiatric Hospital, Calabar, Cross River, Nigeria.
ABSTRACT
Relapse is a fairly common problem for people recovering from substance abuse or addiction in mental health rehabilitation and research hospital Uyo, Akwa Ibom State. although it is a world-wide issues, motivated by these therefore, this research work was carried out to investigate the prevalence and factors influencing relapse among substance abuse patients in mental health rehabilitation and research hospital, between 2015-2020. The objectives set were; to determine the prevalence of relapse among substance abuse patients in MHRRH, to determine the socio-demographic characteristics of relapse among substance abuse patients
Targeted drugs
1. T y r o s i n e. p r o t e i n. k i n a s e. i n h i b i t o r s : Ni l o t i n i b , I ma t i n i b.
2. E G F r e c e p t o r i n h i b i t o r s : G e f i t i n i b , E r l o t i n i b , C e t u x i ma b.
3. A n g i o g e n e s i s. i n h i b i t o r s :
B e v a c i z u ma b , S u n i t i n i b.
4. P r o t e a s o me. i n h i b i t o r : B o r t e z o mi b
Thesis Chapters by Moses Orhero
The study therefore justifies the medicinal properties of Azadirachta indica as utilized in traditional medicine.
AMONG SUBSTANCE ABUSE PATIENTS IN MENTAL
HEALTH REHABILITATION AND RESEARCH
HOSPITAL UYO, AKWA IBOM STATE
By
Orhero Moses*, Ekanem Caroline.
Federal Neuropsychiatric Hospital, Calabar, Cross River, Nigeria.
ABSTRACT
Relapse is a fairly common problem for people recovering from substance abuse or addiction in mental health rehabilitation and research hospital Uyo, Akwa Ibom State. although it is a world-wide issues, motivated by these therefore, this research work was carried out to investigate the prevalence and factors influencing relapse among substance abuse patients in mental health rehabilitation and research hospital, between 2015-2020. The objectives set were; to determine the prevalence of relapse among substance abuse patients in MHRRH, to determine the socio-demographic characteristics of relapse among substance abuse patients
Targeted drugs
1. T y r o s i n e. p r o t e i n. k i n a s e. i n h i b i t o r s : Ni l o t i n i b , I ma t i n i b.
2. E G F r e c e p t o r i n h i b i t o r s : G e f i t i n i b , E r l o t i n i b , C e t u x i ma b.
3. A n g i o g e n e s i s. i n h i b i t o r s :
B e v a c i z u ma b , S u n i t i n i b.
4. P r o t e a s o me. i n h i b i t o r : B o r t e z o mi b
The study therefore justifies the medicinal properties of Azadirachta indica as utilized in traditional medicine.