Papers by Miranda Van Hooff
European Journal of Pain Supplements, 2011
Background and Aims: Inadequate burn-related pain control contributes to poor functional and psyc... more Background and Aims: Inadequate burn-related pain control contributes to poor functional and psychological outcomes, has directly impact on patient's recovery and quality of life (QL). The aim-to investigate the frequency of chronic pain, the quantitative and qualitative assess of their performance, quality of life of patients with burns after 6 months period. Methods: A cross sectional study carried out in Kaunas medical hospital in Lithuania. Standard pain questionnaires were sent by email to burn victims treated in a single burn unit during period of 01/06/2008-30/04/2009. Results: Response rate -36.7%. The mean age of respondents -51.34±16. 68.2% of patients indicated that they are suffering from varied intensity of pain in burnt place, 51.6% -felt severe pain in skin donoric site. Patients, experienced wound infection in acute trauma period, indicates higher NAS score (p = 0.03). 86.3% of our patients were generally noted the emotional scale: one quarterfearful and one-third -tiring, 84.38% were marked neuropathic pain scales: hot burning -36.4%, gnawing -29.5%, tingling -20.5% (p = 0.01). Even 70.4% of our patients due to poor physical wellbeing and emotional problems were limiting social relationships and communication with friends, 43.2% of patients said that postburn pain was limited their usual daily activity. Conclusions: More than half of the patients experienced burn, felt chronic pain in traumatic or donoric place. The intensity of chronic pain directly correlated with the infection of wound during the initial treatment period. Mixed sensory-emotional components were related with chronic post-burn pain.
PLoS ONE, 2014
Background: In Western Europe, low back pain has the greatest burden of all diseases. When back p... more Background: In Western Europe, low back pain has the greatest burden of all diseases. When back pain persists, different medical specialists are involved and a lack of consensus exists among these specialists for medical decision-making in Chronic Low Back Pain (CLBP).
European Spine Journal, 2012
Purpose Cognitive behavioral interventions are recommended as non-invasive treatment options for ... more Purpose Cognitive behavioral interventions are recommended as non-invasive treatment options for patients with chronic low back pain (CLBP). However, most treatment effects are small and short-lived. Although a 2-week intensive pain management program for patients with CLBP seems to be effective, the long-term results are not known. The purpose of this study is to evaluate the stability of the 2-year follow-up results and whether this is reflected in the use of health-care services. Methods A prospective cohort study was performed. Pretreatment characteristics of patients and data of outcomes obtained at 1-year follow-up were used. At 2-year followup a structured interview was conducted following the principles of a post-marketing survey. Outcomes included daily functioning, quality of life, current intensity of pain, disturbance of pain during daily activities, and indicators of the use of pain medication and health-care services. Results Of the 90 eligible patients 85 (94%) participated in the post-marketing survey. The 1-year clinical relevant effects are maintained at 2-year follow-up. Effect sizes for functioning and quality of life were large. More than 65% reached preset minimal clinically important differences. At pre-treatment all patients consulted their general practitioner (GP) and medical specialist (MS). At 2-year followup 73% reported having consulted neither a GP nor an MS during the previous year. Most of the patients indicated not to use any pain medication (57%) and the percentage patients using opioids have decreased (14%). Moreover, 81% reported to be at work. Conclusions The gained results from selected and motivated patients with longstanding CLBP at 1-year follow-up are stable at 2-year follow-up. Above all, most of the participants are at work and results indicate that the use of both pain medication and health care have decreased substantially.
European Spine Journal, 2010
Chronic low back pain (CLBP) is associated with persistent or recurrent disability which results ... more Chronic low back pain (CLBP) is associated with persistent or recurrent disability which results in high costs for society. Cognitive behavioral treatments produce clinically relevant benefits for patients with CLBP. Nevertheless, no clear evidence for the most appropriate intervention is yet available. The purpose of this study is to evaluate the mid-term effects of treatment in a cohort of patients with CLBP participating in an intensive pain management programme. The programme provided by RealHealth-Netherlands is based on cognitive behavioral principles and executed in collaboration with orthopedic surgeons. Main outcome parameters were daily functioning (Roland and Morris Disability Questionnaire and Oswestry Disability Questionnaire), self-efficacy (Pain Self-Efficacy Questionnaire) and quality of life (Short Form 36 Physical Component Score). All parameters were measured at baseline, last day of residential programme and at 1 and 12 months follow-up. Repeated measures analysis was applied to examine changes over time. Clinical relevance was examined using minimal clinical important differences (MCID) estimates for main outcomes. To compare results with literature effect sizes (Cohen's d) and Standardized Morbidity Ratios (SMR) were determined. 107 patients with CLBP participated in this programme. Mean scores on outcome measures showed a similar pattern: improvement after residential programme and maintenance of results over time. Effect sizes were 0.9 for functioning, 0.8 for self-efficacy and 1.3 for physical functioning related quality of life. Clinical relevancy: 79% reached MCID on functioning, 53% on self-efficacy and 80% on quality of life. Study results on functioning were found to be 36% better and 2% worse when related to previous research on, respectively, rehabilitation programmes and spinal surgery for similar conditions (SMR 136 and 98%, respectively). The participants of this evidence-based programme learned to manage CLBP, improved in daily functioning and quality of life. The study results are meaningful and comparable with results of spinal surgery and even better than results from less intensive rehabilitation programmes.
European Spine Journal, 2014
Purpose The aim of this longitudinal study is to determine the factors which predict a successful... more Purpose The aim of this longitudinal study is to determine the factors which predict a successful 1-year outcome from an intensive combined physical and psychological (CPP) programme in chronic low back pain (CLBP) patients. Methods A prospective cohort of 524 selected consecutive CLBP patients was followed. Potential predictive factors included demographic characteristics, disability, pain and cognitive behavioural factors as measured at pretreatment assessment. The primary outcome measure was the oswestry disability index (ODI). A successful 1-year follow-up outcome was defined as a functional status equivalent to 'normal' and healthy populations (ODI B22). The 2-week residential programme fulfills the recommendations in international guidelines. For statistical analysis we divided the database into two equal samples. A random sample was used to develop a prediction model with multivariate logistic regression. The remaining cases were used to validate this model.
Sports Medicine - Open, 2015
Background: Trunk impairment seems to impact significantly on performance in wheelchair court spo... more Background: Trunk impairment seems to impact significantly on performance in wheelchair court sports, but evidence to support this impression has never been systematically assessed. The objective of this study is to systematically review, describe and synthesise the literature investigating the impact of trunk impairment on wheelchair activities in court sports.
Acta orthopaedica, Jan 28, 2015
Background and purpose - Currently, Propionibacterium is frequently recognized as a causative mic... more Background and purpose - Currently, Propionibacterium is frequently recognized as a causative microorganism of prosthetic joint infection (PJI). We assessed treatment success at 1- and 2-year follow-up after treatment of Propionibacterium-associated PJI of the shoulder, hip, and knee. Furthermore, we attempted to determine whether postoperative treatment with rifampicin is favorable. Patients and methods - We conducted a retrospective cohort study in which we included patients with a primary or revision joint arthroplasty of the shoulder, hip, or knee who were diagnosed with a Propionibacterium-associated PJI between November 2008 and February 2013 and who had been followed up for at least 1 year. Results - We identified 60 patients with a Propionibacterium-associated PJI with a median duration of 21 (0.1-49) months until the occurrence of treatment failure. 39 patients received rifampicin combination therapy, with a success rate of 93% (95% CI: 83-97) after 1 year and 86% (CI: 71-9...
Background and purpose — We performed a systematic review and a survey in order to (1) evaluate t... more Background and purpose — We performed a systematic review and a survey in order to (1) evaluate the evidence for the impact of spine registries on the quality of spine care, and with that, on patient-related outcomes, and (2) evaluate the methodology used to organize, analyze, and report the " quality of spine care " from spine registries. Methods — To study the impact, the literature on all spinal disorders was searched. To study methodology, the search was restricted to degenerative spinal disorders. The risk of bias in the studies included was assessed with the Newcastle-Ottawa scale. Additionally, a survey among registry representatives was performed to acquire information about the methodology and practice of existing registries. Results — 4,273 unique references up to May 2014 were identified , and 1,210 were eligible for screening and assessment. No studies on impact were identified, but 34 studies were identified to study the methodology. Half of these studies (17 ...
Sports Medicine - Open, 2015
Background: Trunk impairment seems to impact significantly on performance in wheelchair court spo... more Background: Trunk impairment seems to impact significantly on performance in wheelchair court sports, but evidence to support this impression has never been systematically assessed. The objective of this study is to systematically review, describe and synthesise the literature investigating the impact of trunk impairment on wheelchair activities in court sports.
PLoS ONE, 2014
Background: In Western Europe, low back pain has the greatest burden of all diseases. When back p... more Background: In Western Europe, low back pain has the greatest burden of all diseases. When back pain persists, different medical specialists are involved and a lack of consensus exists among these specialists for medical decision-making in Chronic Low Back Pain (CLBP).
Mobile bearing vs fixed bearing prostheses for posterior cruciate retaining total knee arthroplas... more Mobile bearing vs fixed bearing prostheses for posterior cruciate retaining total knee arthroplasty for postoperative functional status in patients with osteoarthritis and rheumatoid arthritis (Review)
Hip International, 2012
Concerns have recently been raised about large head metal-on-metal total hip arthroplasties (LDH ... more Concerns have recently been raised about large head metal-on-metal total hip arthroplasties (LDH THA). Metal ion release due to wear may cause osteolysis, pseudotumours and necrosis. In addition, fixation of certain acetabular components is thought to be suboptimal. We present the short term outcome of the Durom LDH THA. Retrospectively, a consecutive series of 64 implants in 60 patients was analysed with a mean follow-up of 37 months. Clinical and radiological evaluation was performed on a regular basis, followed by additional evaluations when indicated. The 10-year revision percentage was calculated and compared with National Institute for Health and Clinical Excellence (NICE) standards. Six patients (six hips) underwent cup revision (9%). Four of these cups showed no or minimal bone fixation. Three patients had a pseudotumour. In two revision cases, ALVAL (aseptic lymphocyte-dominated vasculitis-associated lesion) was present. Lack of bone ingrowth and the presence of ARMD (adverse reaction to metal debris) seem to contribute to a high failure rate of the Durom LDH THA. The predicted ten-year revision rate of 14.2% (95% CI 5.6-22.8) is, given the broad confidence interval, not significantly outside NICE recommended standards. However, it is not clear which factors, if any, predict implant failure. Therefore, we do not advocate the use of this implant.
European Spine Journal, 2010
Chronic low back pain (CLBP) is associated with persistent or recurrent disability which results ... more Chronic low back pain (CLBP) is associated with persistent or recurrent disability which results in high costs for society. Cognitive behavioral treatments produce clinically relevant benefits for patients with CLBP. Nevertheless, no clear evidence for the most appropriate intervention is yet available. The purpose of this study is to evaluate the mid-term effects of treatment in a cohort of patients with CLBP participating in an intensive pain management programme. The programme provided by RealHealth-Netherlands is based on cognitive behavioral principles and executed in collaboration with orthopedic surgeons. Main outcome parameters were daily functioning (Roland and Morris Disability Questionnaire and Oswestry Disability Questionnaire), self-efficacy (Pain Self-Efficacy Questionnaire) and quality of life (Short Form 36 Physical Component Score). All parameters were measured at baseline, last day of residential programme and at 1 and 12 months follow-up. Repeated measures analysis was applied to examine changes over time. Clinical relevance was examined using minimal clinical important differences (MCID) estimates for main outcomes. To compare results with literature effect sizes (Cohen's d) and Standardized Morbidity Ratios (SMR) were determined. 107 patients with CLBP participated in this programme. Mean scores on outcome measures showed a similar pattern: improvement after residential programme and maintenance of results over time. Effect sizes were 0.9 for functioning, 0.8 for self-efficacy and 1.3 for physical functioning related quality of life. Clinical relevancy: 79% reached MCID on functioning, 53% on self-efficacy and 80% on quality of life. Study results on functioning were found to be 36% better and 2% worse when related to previous research on, respectively, rehabilitation programmes and spinal surgery for similar conditions (SMR 136 and 98%, respectively). The participants of this evidence-based programme learned to manage CLBP, improved in daily functioning and quality of life. The study results are meaningful and comparable with results of spinal surgery and even better than results from less intensive rehabilitation programmes.
European Spine Journal, 2012
Purpose Cognitive behavioral interventions are recommended as non-invasive treatment options for ... more Purpose Cognitive behavioral interventions are recommended as non-invasive treatment options for patients with chronic low back pain (CLBP). However, most treatment effects are small and short-lived. Although a 2-week intensive pain management program for patients with CLBP seems to be effective, the long-term results are not known. The purpose of this study is to evaluate the stability of the 2-year follow-up results and whether this is reflected in the use of health-care services. Methods A prospective cohort study was performed. Pretreatment characteristics of patients and data of outcomes obtained at 1-year follow-up were used. At 2-year followup a structured interview was conducted following the principles of a post-marketing survey. Outcomes included daily functioning, quality of life, current intensity of pain, disturbance of pain during daily activities, and indicators of the use of pain medication and health-care services. Results Of the 90 eligible patients 85 (94%) participated in the post-marketing survey. The 1-year clinical relevant effects are maintained at 2-year follow-up. Effect sizes for functioning and quality of life were large. More than 65% reached preset minimal clinically important differences. At pre-treatment all patients consulted their general practitioner (GP) and medical specialist (MS). At 2-year followup 73% reported having consulted neither a GP nor an MS during the previous year. Most of the patients indicated not to use any pain medication (57%) and the percentage patients using opioids have decreased (14%). Moreover, 81% reported to be at work. Conclusions The gained results from selected and motivated patients with longstanding CLBP at 1-year follow-up are stable at 2-year follow-up. Above all, most of the participants are at work and results indicate that the use of both pain medication and health care have decreased substantially.
European Spine Journal, 2014
Purpose The aim of this longitudinal study is to determine the factors which predict a successful... more Purpose The aim of this longitudinal study is to determine the factors which predict a successful 1-year outcome from an intensive combined physical and psychological (CPP) programme in chronic low back pain (CLBP) patients. Methods A prospective cohort of 524 selected consecutive CLBP patients was followed. Potential predictive factors included demographic characteristics, disability, pain and cognitive behavioural factors as measured at pretreatment assessment. The primary outcome measure was the oswestry disability index (ODI). A successful 1-year follow-up outcome was defined as a functional status equivalent to 'normal' and healthy populations (ODI B22). The 2-week residential programme fulfills the recommendations in international guidelines. For statistical analysis we divided the database into two equal samples. A random sample was used to develop a prediction model with multivariate logistic regression. The remaining cases were used to validate this model.
European Journal of Pain Supplements, 2011
Background and Aims: Improved function is a pain management outcome but suffers from a lack of si... more Background and Aims: Improved function is a pain management outcome but suffers from a lack of simple quick tests. Data on multidisciplinary clinics (MDC) and functional goals are limited. This study evaluates the use of the 6-minute walk test (6MWT) in a heterogeneous group of chronic pain patients. Methods: This chart review was approved by the Clinic Ethics Board. This study used the 6MWT in determining functional improvement over time in 37 patients evaluated upon entering the MDC, and again 3-6 months later. During this time, patients were exposed to a full range of possible MDC therapeutic modalities. As this was a chart review study, interventions followed a typical course and were driven by clinical presentation and judgment of the managing physician. Results: At pre-evaluation, patients were able to walk an average of 274.05 yards. At follow-up, mean walk distances had improved to 349.46 yards, which represented a significant improvement (t 1,36 = 17.08, p < 0.0001). Conclusions: Thus, there is evidence that MDC services can have an impact on functionality and that the 6MWT may be a suitable addition to assessing pain patients. Improved function is an important goal in pain patients, especially those on opioids and the 6MWT show promise for assessment, although it is not validated in chronic pain, except in fibromyalgia patients. This study is ongoing, prospective and now part of the clinical evaluation of all patients entering the MDC. We plan on validating the 6MWT in the chronic pain population.
European Journal of Pain Supplements, 2011
Background and Aims: Inadequate burn-related pain control contributes to poor functional and psyc... more Background and Aims: Inadequate burn-related pain control contributes to poor functional and psychological outcomes, has directly impact on patient's recovery and quality of life (QL). The aim-to investigate the frequency of chronic pain, the quantitative and qualitative assess of their performance, quality of life of patients with burns after 6 months period. Methods: A cross sectional study carried out in Kaunas medical hospital in Lithuania. Standard pain questionnaires were sent by email to burn victims treated in a single burn unit during period of 01/06/2008-30/04/2009. Results: Response rate -36.7%. The mean age of respondents -51.34±16. 68.2% of patients indicated that they are suffering from varied intensity of pain in burnt place, 51.6% -felt severe pain in skin donoric site. Patients, experienced wound infection in acute trauma period, indicates higher NAS score (p = 0.03). 86.3% of our patients were generally noted the emotional scale: one quarterfearful and one-third -tiring, 84.38% were marked neuropathic pain scales: hot burning -36.4%, gnawing -29.5%, tingling -20.5% (p = 0.01). Even 70.4% of our patients due to poor physical wellbeing and emotional problems were limiting social relationships and communication with friends, 43.2% of patients said that postburn pain was limited their usual daily activity. Conclusions: More than half of the patients experienced burn, felt chronic pain in traumatic or donoric place. The intensity of chronic pain directly correlated with the infection of wound during the initial treatment period. Mixed sensory-emotional components were related with chronic post-burn pain.
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Papers by Miranda Van Hooff