Papers by Melissa Neubacher
Hebammen Wissen, 2021
in vermehrter peripartaler Blutverlust wird definiert als Blutungsmenge von über 500 ml nach vagi... more in vermehrter peripartaler Blutverlust wird definiert als Blutungsmenge von über 500 ml nach vaginaler Geburt oder über 1.000 ml nach Sectio caesarea. Die Ursachen und Risikofaktoren für peripartale Blutungen werden nach den "4 T's"-Trauma, Tissue (Plazentare Ursachen), Thrombin (Gerinnungsstörungen) und Tonus (Atonie)-zusammengefasst (Tab. 1).
Journal of Clinical Oncology, 2018
e24096Background: Predictive relevance of circulating tumor cells (CTCs) in metastatic breast can... more e24096Background: Predictive relevance of circulating tumor cells (CTCs) in metastatic breast cancer (MBC) patients has been shown in several clinical trials. Moreover identification of predictive ...
Frauenheilkunde im Fokus: wissenschaftlich fundiert und der Qualität verpflichtet, 2018
Senologie - Zeitschrift für Mammadiagnostik und -therapie, 2017
XXV. Akademische Tagung Deutschsprachiger Hochschullehrer der Gynäkologie und Geburtshilfe, 2017
BMC Cancer, 2019
Background The prognostic relevance of circulating tumour cells (CTCs) in metastatic breast cance... more Background The prognostic relevance of circulating tumour cells (CTCs) in metastatic breast cancer (MBC) patients has been confirmed by several clinical trials. However, predictive blood-based biomarkers for stratification of patients for targeted therapy are still lacking. The DETECT studies explore the utility of CTC phenotype for treatment decisions in patients with HER2 negative MBC. Associated with this concept is a plethora of translational projects aiming to identify potential predictive biomarkers. The androgen receptor (AR) is expressed in over 70% of hormone receptor-positive and up-to 45% of triple-negative tumours. Studies has indicated the promising nature of AR as a new therapy target with a clinical benefit rate for anti-AR treatment in MBC patients up to 25% The aim of this analysis was the characterization of CTCs regarding the expression of the AR using immunofluorescence. Methods MBC patients were screened for the HER2-status of CTCs in the DETECT studies. In a su...
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Papers by Melissa Neubacher