Papers by Luiz Carlos Vanderlei
Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, Jan 25, 2017
To evaluate the influence of functional training on the geometric indices of heart rate variabili... more To evaluate the influence of functional training on the geometric indices of heart rate variability (HRV) and fractal correlation properties of the dynamics of heart rate in menopausal women. Of 39 women who were in the period of menopause for more than a year and who did not practice any regular physical activity were divided into: Functional training group (FTG = 50 ± 4.5 years; 67.64 ± 11.64 kg; 1.5 ± 0.05 m) that executed the functional training (FT) and all proposals by reviews and the Control group (58.45 ± 4.8 years; 66.91 ± 13.24 kg; 1.55 ± 0.05 m) who performed all assessments but not FT. The training consisted of 18 weeks (three times a week) and the volunteers performed three sets of 11 functional exercises followed by a walk in each of the sessions. The autonomic nervous system modulation was evaluated by analysis of HRV and the indices obtained were: RR intervals, RRTRI, TINN, SD1, SD2, SD1/SD2, qualitative analysis of Poincaré plot and DFA (alfa-1, alfa-2 and alfa-1/al...
Journal of Human Growth and Development, 2013
A literatura já demonstrou que a estimulação auditiva por meio de música influencia o sistemacard... more A literatura já demonstrou que a estimulação auditiva por meio de música influencia o sistemacardiovascular. Neste estudo, foi realizada uma revisão da literatura, a fim de investigar a relaçãoentre os mecanismos auditivos e a regulação autonômica cardíaca. Os estudos selecionados indicaramforte correlação entre a intensidade do ruído e o equilíbrio simpatovagal. Além disso, foi relatadoque a terapia com música melhorou a variabilidade da frequência cardíaca em pacientes com câncerde mama tratados com antraciclinas. Postula-se que a dopamina liberada no sistema estriatal,induzida por canções alegres, está envolvida na regulação autonômica. Estudos posteriores sãonecessários para adicionar novos elementos na literatura, para melhorar a novas terapias e para otratar doenças cardiovasculares.
Brazilian Journal of Medical and Biological Research, 2008
The aim of the present study was to compare heart rate variability (HRV) at rest and during exerc... more The aim of the present study was to compare heart rate variability (HRV) at rest and during exercise using a temporal series obtained with the Polar S810i monitor and a signal from a LYNX ® signal conditioner (BIO EMG 1000 model) with a channel configured for the acquisition of ECG signals. Fifteen healthy subjects aged 20.9 ± 1.4 years were analyzed. The subjects remained at rest for 20 min and performed exercise for another 20 min with the workload selected to achieve 60% of submaximal heart rate. RR series were obtained for each individual with a Polar S810i instrument and with an ECG analyzed with a biological signal conditioner. The HRV indices (rMSSD, pNN50, LFnu, HFnu, and LF/HF) were calculated after signal processing and analysis. The unpaired Student t-test and intraclass correlation coefficient were used for data analysis. No statistically significant differences were observed when comparing the values analyzed by means of the two devices for HRV at rest and during exercise. The intraclass correlation coefficient demonstrated satisfactory correlation between the values obtained by the devices at rest (pNN50 = 0.994; rMSSD = 0.995; LFnu = 0.978; HFnu = 0.978; LF/HF = 0.982) and during exercise (pNN50 = 0.869; rMSSD = 0.929; LFnu = 0.973; HFnu = 0.973; LF/HF = 0.942). The calculation of HRV values by means of temporal series obtained from the Polar S810i instrument appears to be as reliable as those obtained by processing the ECG signal captured with a signal conditioner.
Türk Kardiyoloji Derneği arşivi : Türk Kardiyoloji Derneğinin yayın organıdır, 2014
The effects of chronic music auditory stimulation on the cardiovascular system have been investig... more The effects of chronic music auditory stimulation on the cardiovascular system have been investigated in the literature. However, data regarding the acute effects of different styles of music on cardiac autonomic regulation are lacking. The literature has indicated that auditory stimulation with white noise above 50 dB induces cardiac responses. We aimed to evaluate the acute effects of classical baroque and heavy metal music of different intensities on cardiac autonomic regulation. The study was performed in 16 healthy men aged 18-25 years. All procedures were performed in the same soundproof room. We analyzed heart rate variability (HRV) in time (standard deviation of normal-to-normal R-R intervals [SDNN], root-mean square of differences [RMSSD] and percentage of adjacent NN intervals with a difference of duration greater than 50 ms [pNN50]) and frequency (low frequency [LF], high frequency [HF] and LF/HF ratio) domains. HRV was recorded at rest for 10 minutes. Subsequently, the v...
Introduction: in recent years, several studies have performed the behavior of ANS on obesity by t... more Introduction: in recent years, several studies have performed the behavior of ANS on obesity by the heart rate variability (HRV). The literature describes that obese adults have dysfunctions on ANS, nevertheless there is a few information with childhood obesity and the findings are still inconclusive. Objective: gathering studies that approach the analysis of the ANS by HRV in obese children to understand better the influence of obesity on this system and in this population and provide an update of the findings published in the last eleven years. Methods: the search of articles was conducted on Pubmed, Ibesc, Medline, Scielo, Cochrane and Lilacs databases using the keywords: heart rate, autonomic nervous system, obesity, child and sympathetic nervous system of health subject headings (MeSH). Results: the electronic search resulted in 11 articles and, in general, showed a decrease in activity of the parasympathetic branch of obese children and inconclusive results by the sympathetic branch. Moreover, interventions as diet and physical activity "could increase the ANS function in these children. Conclusion: obese children have changes on ANS function and this presents the necessity of precocious attention aims at avoiding future complications.
International Archives of Medicine, 2013
Introduction: The apical ballooning syndrome (ABS) is a single reversible cardiomyopathy often tr... more Introduction: The apical ballooning syndrome (ABS) is a single reversible cardiomyopathy often triggered by a stressful event. We aimed to present a case report regarding this disorder. Case presentation: Here we present the case of a 77-year-old female hypertensive patient, sedentary and non-smoker, diagnosed with apical ballooning syndrome. We describe the clinical signs and symptoms, changes in markers of myocardial necrosis and changes in the electrocardiogram and coronary angiography. Conclusion: The course of events patient showed clinical improvement with treatment and support was not necessary to administer specific medications or interventions to reverse the situation. After hemodynamic stabilization coronary angiography showed no obstructive lesions and left ventricle with akinesia of the apex and the middle portion of the left ventricle.
Journal of Human Growth and Development, 2014
The aim of this study is to assess the risk of dynamical diseases in malnourished children. This ... more The aim of this study is to assess the risk of dynamical diseases in malnourished children. This is achieved by the application of novel chaotic global techniques to the RR-intervals of the electrocardiogram (ECG) in the cohort. Heart Rate Variability (HRV) is an inexpensive and non-invasive tool to measure the autonomic impulses. Here there has been a decrease in chaotic response of HRV. Seventy children were divided into equal groups and the HRV monitored for 20-25 minutes. The Chaos Forward Parameter (CFP) which applies all three chaotic global parameters is suggested to be the most robust algorithm. These three parameters are high spectral entropy (hsEntropy), high spectral detrended fluctuation analysis (hsDFA) and spectral multi-taper method (sMTM). hsEntropy is a function of the irregularity of amplitude and frequency of the power spectrums peaks. It is derived by applying Shannon entropy to the multi-taper method power spectrum. To derive hsDFA we calculate the spectral adaptation in exactly the same way as for hsEntropy using an adaptive multi-taper method power spectrum with the same settings; but DFA rather than Shannon entropy is the algorithm applied. sMTM is the area between the multi-taper method power spectrum and the baseline. After Anderson-Darling and Lilliefors tests of normality; Kruskal-Wallis was used for the statistical analysis, with the level of significance set at (p < 0.01). Principal Component Analysis (PCA) identified two components representing 100% of total variance. Autonomic imbalance measured as HRV and an increased cardiovascular risk are described for overweight children as well as for malnourished and those with anorexia nervosa. The relationship between malnourishment and complexity measures is useful in the risk assessment of dynamical diseases associated with the condition. This is supportive in treatments, assisting the determination of the level of dietary or pharmacological intervention especially in related dynamical diseases.
International Archives of Medicine, 2013
Background: Chronic exposure to musical auditory stimulation has been reported to improve cardiac... more Background: Chronic exposure to musical auditory stimulation has been reported to improve cardiac autonomic regulation. However, it is not clear if music acutely influences it in response to autonomic tests. We evaluated the acute effects of music on heart rate variability (HRV) responses to the postural change maneuver (PCM) in women. Method: We evaluated 12 healthy women between 18 and 28 years old and HRV was analyzed in the time (SDNN, RMSSD, NN50 and pNN50) and frequency (LF, HF and LF/HF ratio) domains. In the control protocol, the women remained at seated rest for 10 minutes and quickly stood up within three seconds and remained standing still for 15 minutes. In the music protocol, the women remained at seated rest for 10 minutes, were exposed to music for 10 minutes and quickly stood up within three seconds and remained standing still for 15 minutes. HRV was recorded at the following time: rest, music (music protocol) 0-5, 5-10 and 10-15 min during standing. Results: In the control protocol the SDNN, RMSSD and pNN50 indexes were reduced at 10-15 minutes after the volunteers stood up, while the LF (nu) index was increased at the same moment compared to seated rest. In the protocol with music, the indexes were not different from control but the RMSSD, pNN50 and LF (nu) were different from the music period. Conclusion: Musical auditory stimulation attenuates the cardiac autonomic responses to the PCM.
ABCS Health Sciences, 2013
Introduction: The literature has shown that musical stimulation can influence the cardiovascular ... more Introduction: The literature has shown that musical stimulation can influence the cardiovascular system, however, the neurophysiological aspects of this influence are not yet fully elucidated. Objective: This study describes the influence of music on the neurophysiological mechanisms in the human body, specifically the variable blood pressure, as well as the neural mechanisms of music processing. Methods: Searches were conducted in Medline, PEDro, Lilacs and SciELO using the intersection of the keyword “music” with the keyword descriptors “blood pressure” and “neurophysiology”. Results: There were selected 11 articles, which indicated that music interferes in some aspects of physiological variables. Conclusion: Studies have indicated that music interferes on the control of blood pressure, heart and respiratory rate, through possible involvement of limbic brain areas which modulate hypothalamic-pituitary functions. Further studies are needed in order to identify the mechanisms by whi...
Arquivos Brasileiros de Ciências da Saúde, 2012
Introdução: A variabilidade da frequência cardíaca (VFC) tem sido utilizada como medida do balanç... more Introdução: A variabilidade da frequência cardíaca (VFC) tem sido utilizada como medida do balanço autonômico, ou seja, da relação entre o sistema simpático e o parassimpático, sendo, indiretamente, um indicativo do nível homeostático do indivíduo. Há relatos de redução da VFC em cardiopatias congênitas, mas não há estudos mais sistematizados buscando correlação entre a gravidade estrutural e funcional da cardiopatia e o grau de redução da variabilidade. Objetivo: Conduzir um estudo piloto em um grupo de cardiopatas congênitos buscando indícios de menor VFC correlacionada à pior condição estrutural ou funcional da cardiopatia em questão. Método: Foram avaliados 17 pacientes, sendo 11 portadores de cardiopatias congênitas consideradas de baixo impacto estrutural e seis com cardiopatias cianogênicas graves. Foi feita a captação das séries temporais por meio do equipamento Polar RS800® em situação de repouso, na posição supina, no período da manhã, selecionando-se 1 mil intervalos RR c...
Medical Express, 2014
Among the benefits provided by resistance training, its influence on cardiac autonomic modulation... more Among the benefits provided by resistance training, its influence on cardiac autonomic modulation draws attention, given the importance of the autonomic nervous system in the control of the internal functions of the body. The objective of this narrative review was to gather information about the effects of resistance training on autonomic modulation in healthy young adults, assessed through heart rate variability. This search was performed in May 2013 in the following databases: Medical Literature Analysis and Retrieval System Online (MEDLINE/PubMed), Physiotherapy Evidence Database (PEDro), Scientific Electronic Library Online (SciELO) and Literature and Latin American and Caribbean Health Sciences (LILACS), with articles published between January 2003 and March 2013. The keywords used were: "resistance training," "lifting," "exercise therapy" crossreferenced with "autonomic nervous system" and "parasympathetic nervous system" and also the term "heart rate variability". Of the 1,940 titles found, 3 complete articles were selected to compose the review. Data were analyzed qualitatively. The analysis of these studies suggests that resistance training can change the heart rate variability indices in the population of healthy young adults and that this change is due to increased vagal activity, provided by the practice of this type of training.
Noise and Health, 2014
It is poor in the literature the behavior of the geometric indices of heart rate variability (HRV... more It is poor in the literature the behavior of the geometric indices of heart rate variability (HRV) during the musical auditory stimulation. The objective is to investigate the acute effects of classic musical auditory stimulation on the geometric indexes of HRV in women in response to the postural change maneuver (PCM). We evaluated 11 healthy women between 18 and 25 years old. We analyzed the following indices: Triangular index, Triangular interpolation of RR intervals and Poincarι plot (standard deviation of the instantaneous variability of the beat-to beat heart rate [SD1], standard deviation of long-term continuous RR interval variability and Ratio between the short - and long-term variations of RR intervals [SD1/SD2] ratio). HRV was recorded at seated rest for 10 min. The women quickly stood up from a seated position in up to 3 s and remained standing still for 15 min. HRV was recorded at the following periods: Rest, 0-5 min, 5-10 min and 10-15 min during standing. In the second protocol, the subject was exposed to auditory musical stimulation (Pachelbel-Canon in D) for 10 min at seated position before standing position. Shapiro-Wilk to verify normality of data and ANOVA for repeated measures followed by the Bonferroni test for parametric variables and Friedman&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;#39;s followed by the Dunn&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;#39;s posttest for non-parametric distributions. In the first protocol, all indices were reduced at 10-15 min after the volunteers stood up. In the protocol musical auditory stimulation, the SD1 index was reduced at 5-10 min after the volunteers stood up compared with the music period. The SD1/SD2 ratio was decreased at control and music period compared with 5-10 min after the volunteers stood up. Musical auditory stimulation attenuates the cardiac autonomic responses to the PCM.
Journal of the International Society of Sports Nutrition, 2013
Background: With prolonged physical activity, it is important to maintain adequate fluid balance.... more Background: With prolonged physical activity, it is important to maintain adequate fluid balance. The impact of consuming isotonic drinks during and after exercise on the autonomic regulation of cardiac function is unclear. This study aimed to analyze the effects of consuming an isotonic drink on heart rate variability (HRV) during and after prolonged exercise. Methods: Thirty-one young males (21.55 ± 1.89 yr) performed three different protocols (48 h interval between each stage): I) maximal exercise test to determine the load for the protocols; II) Control protocol (CP) and; III). Experimental protocol (EP). The protocols consisted of 10 min at rest with the subject in the supine position, 90 min of treadmill exercise (60% of VO 2 peak) and 60 min of rest placed in the dorsal decubitus position. No rehydration beverage consumption was allowed during CP. During EP, however, the subjects were given an isotonic solution (Gatorade, Brazil) containing carbohydrate (30 g), sodium (225 mg), chloride (210 mg) and potassium (60 mg) per 500 ml of the drink. For analysis of HRV data, time and frequency domain indices were investigated. HRV was recorded at rest (5-10 min), during exercise (25-30 min, 55-60 min and 85-90 min) and post-exercise (5-10 min, 15-20 min, 25-30 min, 40-45 min and 55-60 min). Results: Regardless of hydration, alterations in the SNS and PSNS were observed, revealing an increase in the former and a decrease in the latter. Hydrating with isotonic solution during recovery induced significant changes in cardiac autonomic modulation, promoting faster recovery of linear HRV indices. Conclusion: Hydration with isotonic solution did not significantly influence HRV during exercise; however, after exercise it promoted faster recovery of linear indices.
Arquivos Brasileiros de Cardiologia, 2010
Background: Obesity causes changes in cardiac autonomic modulation. Objective: To investigate the... more Background: Obesity causes changes in cardiac autonomic modulation. Objective: To investigate the autonomic modulation of eutrophic and obese children by means of indexes of heart rate variability (HRV) obtained through geometric methods. Methods: We analyzed data from 133 children aged 8 to 13, divided into two groups: obese (n = 61) and eutrophic (n = 72) according to body mass index for age and sex. For the analysis of HRV, heart rate was recorded beat-to-beat. The RR intervals were transformed into geometric figures, and from them, we calculated the triangular index (RRtri), triangular interpolation of RR intervals (TINN), the indexes SD1, SD2 and SD1/SD2 ratio, obtained from the Poincaré plot. Visual analysis of the plot was also performed. Student's t test was performed for unpaired data and Mann-Whitney's test, with significance level of 5.0%, for data analysis. Results: In obese children, RRtri indexes were proven to be reduced (0.0730 vs 0.1084 [median]),
Resumo Objetivo: descrever a função autonômica cardíaca de adolescentes saudáveis entre 13 e 18 a... more Resumo Objetivo: descrever a função autonômica cardíaca de adolescentes saudáveis entre 13 e 18 anos. Método: foram analisados dados de 93 adolescentes, de ambos os sexos, divididos em três grupos de acordo com a faixa etária: Grupo A de 13 a 14 anos (n=26), Grupo B de 15 a 16 anos (n = 30) e Grupo C de 17 a 18 anos (n = 17). O protocolo consistiu na captação da frequência cardíaca, batimento a batimento, durante vinte minutos em repouso na posição supino, com respiração espontânea. A análise do comportamento autonômico cardíaco foi realizada pelo método da variabilidade da frequência cardíaca (VFC), por meio dos índices do plot de Poincaré (SD1, SD2 e relação SD1/SD2) e sua análise qualitativa, e dos índices lineares no domínio do tempo (RMSSD e SDNN) e da frequência (LFun, HFun e LF/HF). Teste de One-Way Anova ou teste de Kruskal-Wallis foi aplicado para comparação intergrupos, com nível de significância de 5%. Resultados: não houve diferença significante em nenhum dos índices quando comparados os três grupos estudados. Além disso, a análise visual do plot de Poincaré permitiu observar para todas as faixas etárias avaliadas grandes dispersões dos intervalos RR, indicando que esses grupos apresentam boa VFC. Conclusão: não ocorreram modificações da VFC nas diferentes faixas etárias analisadas, no entanto os resultados permitiram estabelecer um padrão para cada grupo estudado, tornando-se importante ferramenta para comparação da função autonômica cardíaca entre sujeitos saudáveis e doentes, ou em diversos âmbitos.
Revista Paulista de Pediatria, 2014
OBJECTIVE:To gather current information about the effects of type 1 diabetes mellitus on children... more OBJECTIVE:To gather current information about the effects of type 1 diabetes mellitus on children's cardiac autonomic behavior.DATA SOURCES: The search of articles was conducted on PubMed, Ibecs, Medline, Cochrane, Lilacs, SciELO and PEDro databases using the MeSH terms: "autonomic nervous system", "diabetes mellitus", "child", "type 1 diabetes mellitus", "sympathetic nervous system" and "parasympathetic nervous system", and their respective versions in Portuguese (DeCS). Articles published from January 2003 to February 2013 that enrolled children with 9-12 years old with type 1 diabetes mellitus were included in the review.DATA SYNTHESIS: The electronic search resulted in four articles that approached the heart rate variability in children with type 1 diabetes mellitus, showing that, in general, these children present decreased global heart rate variability and vagal activity. The practice of physical activity promoted...
Revista brasileira de cirurgia cardiovascular : orgao oficial da Sociedade Brasileira de Cirurgia Cardiovascular, 2009
Autonomic nervous system (ANS) plays an important role in the regulation of the physiological pro... more Autonomic nervous system (ANS) plays an important role in the regulation of the physiological processes of the human organism during normal and pathological conditions. Among the techniques used in its evaluation, the heart rate variability (HRV) has arising as a simple and non-invasive measure of the autonomic impulses, representing one of the most promising quantitative markers of the autonomic balance. The HRV describes the oscillations in the interval between consecutive heart beats (RR interval), as well as the oscillations between consecutive instantaneous heart rates. It is a measure that can be used to assess the ANS modulation under physiological conditions, such as wakefulness and sleep conditions, different body positions, physical training and also pathological conditions. Changes in the HRV patterns provide a sensible and advanced indicator of health involvements. Higher HRV is a signal of good adaptation and characterizes a health person with efficient autonomic mechan...
Journal of Human Growth and Development, 2017
Objectives: The aim of this study was to determine the prevalence of abdominal obesity and its as... more Objectives: The aim of this study was to determine the prevalence of abdominal obesity and its associated factors among adolescents, independent of confounders. Method: A sample of 14–17-year-old individuals (n=1.231), who were students from Londrina/PR-Brazil public schools, was studied. A questionnaire about physical activity, sedentary behaviour and socioeconomic conditions was applied. Anthropometry was composed of body weight (kg), height (m), body mass index (BMI=kg/m²) and waist circumference (cm). The association of abdominal obesity and independent variables was assessed using the chi-square test and the magnitude of associations was verified using Binary Logistic Regression in an unadjusted model and adjusted for confounders (gender, age, socioeconomic status, physical activity and sedentary behaviour). The confidence interval and statistical significance were set at 95% and 5%, respectively, using SPSS v15.0. Results: The abdominal obesity prevalence was 17.5% (CI = 15.4%...
Fisioterapia E Pesquisa, 1998
O objetivo desse trabalho foi analisar as alteracoes de sensibilidade as catecolaminas em atrios ... more O objetivo desse trabalho foi analisar as alteracoes de sensibilidade as catecolaminas em atrios direitos isolados (AD) de ratas submetidas a estresse por choques nas patas e sacrificadas no estro ou diestro. Foram utilizadas ratas Wistar adultas, com ciclo estral regular de 4 dias, submetidas a 3 sessoes de choques nas patas no estro, metaestro e diestro ou no diestro, proestro e estro. Cada rata recebeu, durante 30 minutos, 120 choques nas patas (1,0 mA, 1,0 s), a intervalos variaveis de 5 a 25 segundos. Apos a ultima sessao de choques, os animais foram sacrificados e o AD preparado para registro isometrico das contracoes espontâneas. Curvas concentracao/efeito para noradrenalina (NA), adrenalina (ADR) e soterenol (SO) foram obtidas sem tratamento farmacologico. Para analisar os mecanismos envolvidos com as alteracoes de sensibilidade observadas, foram utilizados um ou mais dos seguintes tratamentos farmacologicos: desnervacao adrenergica, inibicao dos sistemas de captacao extraneuronal e de recaptacao neuronal, bem como, bloqueio dos adrenoceptores `alfa´ e muscarinicos. Os dados foram comparados atraves de analise de variância seguida da aplicacao do teste de Scheffe, e pelo teste t de Student. Diferencas foram consideradas significantes ao nivel de 5%. AD de ratas, submetidas a choques nas patas e sacrificadas no diestro, apresentaram subsensibilidade a ADR (pD2 = 7,38 `+ ou -´ 0,09 vs. 6,63 `+ ou -´ 0,08), NA (pD2 = 7,67 `+ ou -´ 0,11 vs. 6,95 `+ ou -´ 0,13) e SO (pD2 = 6,80 `+ ou -´ 0,13 vs. 6,36 `+ ou -´ 0,07), quando comparados com os respectivos controles. A inibicao do processo de recaptacao neuronal cancelou a subsensibilidade a NA (pD2 = 7,88 `+ ou -´ 0,06 vs. 7,73 `+ ou -´ 0,08). Apos a realizacao de tratamento farmacologico completo, AD desses animais continuaram a apresentar subsensibilidade a NA (pD2 = 8,10 `+ ou -´ 0,11 vs. 7,68 `+ ou -´ 0,14), enquanto que a subsensibilidade para a ADR foi cancelada (pD2 = 7,67 `+ ou -´ 0,13 vs. 7,49 `+ ou -´ 0,08). Adicao de butoxamina tomou novamente evidente a subsensibilidade a ADR (pD2 = 7,51 `+ ou -´ 0,05 vs. 7,15 `+ ou -´ 0,13). Em AD de ratas estressadas e sacrificadas no estro, somente foi observada subsensibilidade aos efeitos cronotropicos da adrenalina, apos a adicao de butoxamina (pD2 = 7,59 `+ ou -´ 0,05 vs. 7,17 `+ ou -´ 0,07). Estes resultados sugerem que, apos estresse por choques nas patas, AD de ratas sacrificadas no diestro apresentaram aumento da eficiencia do processo de recaptacao neuronal, essensibilizacao dos adrenoceptores `beta 1´ e participacao dos adrenoceptores `beta 2´ na resposta cronotropica as catecolaminas. Durante o estro, os mecanismos adaptativos do controle cronotropico dos AD pelas catecolaminas nao ocorrem, com excecao da participacao dos adrenoceptores `beta 2´ na mediacao da resposta cronotropica Abstract
Brazilian Journal of Physical Therapy, 2010
Contextualização: A ação da nicotina no sistema nervoso autônomo (SNA) propicia altos índices de ... more Contextualização: A ação da nicotina no sistema nervoso autônomo (SNA) propicia altos índices de morbi-mortalidade por doenças cardiovasculares. O estudo da variabilidade da frequência cardíaca (VFC) pode oferecer uma melhor compreensão do controle autonômico cardíaco, além de predizer riscos de eventos cardíacos. Objetivo: Avaliar a modulação autonômica cardíaca, por meio de índices de VFC de indivíduos fumantes e não fumantes. Método: Foram avaliados 39 indivíduos (21 fumantes (G1) e 18 não fumantes (G2) com idade de 44,49 ± 3,54 anos e índice de massa corpórea (IMC) 26,63 ± 4,34 kg/m 2. Os índices de VFC foram avaliados por meio do cardiofrequencímetro Polar S810i em métodos lineares (RMSSD, LF, HF e LF/HF) e não-lineares pelo plot de Poincaré (SD1, SD2). Resultados: Mostraram diferenças significantes os índices LF (nu) (69,69 ± 15,03 vs. 54,98 ± 15,34), HF (nu) (30,31 ± 15,03 vs. 45,02 ± 15,35) e LF/HF (2,58 vs. 1,33) (p<0,05) em fumantes e não fumantes. Entretanto, os valores de RMSSD não apresentaram diferenças significantes entre os grupos (G1 = 24,8 vs. G2 = 30,1). Os índices do plot de Poincaré também não apresentaram diferença estatística entre G1 e G2: SD1(17,8 vs. 21,5) e SD2 (60,2 vs. 56,15). Conclusão: Neste estudo, indivíduos tabagistas apresentaram modificações autonômicas em comparação aos não tabagistas, caracterizadas pelo aumento da atividade simpática (evidenciado pelo índice LF) e consequente redução da atividade parassimpática (evidenciada pelo índice HF). Tal fato pode explicar o maior índice de morbidade e mortalidade cardiovascular em indivíduos fumantes. Palavras-chave: frequência cardíaca; tabagismo; sistema nervoso autônomo.
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