Distintas fuentes coinciden en situar a la insuficiencia cardiaca (IC) como uno de los problemas ... more Distintas fuentes coinciden en situar a la insuficiencia cardiaca (IC) como uno de los problemas sanitarios mas graves a los que se enfrentan los distintos sistemas sanitarios de los paises occidentales en la actualidad y mas aun en las proximas decadas. Asi como la mortalidad (tasas ajustadas por edad) debida a la cardiopatia isquemica y a los accidentes cerebrovasculares, se encuentra en descenso desde hace mas de 25 anos, la mortalidad debida a IC va aumentando. La IC es la tercera causa de muerte por enfermedad cardiovascular en Espana, causando cerca del 25% de fallecimientos por esta causa (tras el ictus y la cardiopatia isquemica). Por todo ello, la IC es un importante problema de salud publica en Espana, al igual que en otros paises desarrollados. Ademas, la magnitud del problema crecera en los proximos anos por el progresivo envejecimiento de la poblacion. Se aprecia como mas de 8 millones de espanoles sobrepasaran los 65 anos en el 2021. Solo por este motivo, la prevalenci...
Conclusiones: Este estudio demuestra de una forma indirecta los cambios epidemiológicos que se es... more Conclusiones: Este estudio demuestra de una forma indirecta los cambios epidemiológicos que se están produciendo en el ictus. Existe suficiente evidencia que indica un cambio epidemiológico al aumentar la tasa de hospitalizaciones en adultos jóvenes.
Revista espanola de cardiologia (English ed.), Jan 18, 2017
Atrial fibrillation (AF) is an independent risk factor for mortality in several diseases. However... more Atrial fibrillation (AF) is an independent risk factor for mortality in several diseases. However, data published in acute decompensated heart failure (DHF) are contradictory. Our objective was to investigate the impact of AF on mortality in patients admitted to hospital for DHF compared with those admitted for other reasons. This retrospective cohort study included all patients admitted to hospital within a 10-year period due to DHF, acute myocardial infarction (AMI), or ischemic stroke (IS), with a median follow-up of 6.2 years. We included 6613 patients (74 ± 11 years; 54.6% male); 2177 with AMI, 2208 with DHF, and 2228 with IS. Crude postdischarge mortality was higher in patients with AF hospitalized for AMI (incident rate ratio, 2.48; P < .001) and IS (incident rate ratio, 1.84; P < .001) than in those without AF. No differences were found in patients with DHF (incident rate ratio, 0.90; P = .12). In adjusted models, AF was not an independent predictor of in-hospital mort...
Sánchez L, et al. Risk factors and therapeutic coverage at 6 years in patients with previous myoc... more Sánchez L, et al. Risk factors and therapeutic coverage at 6 years in patients with previous myocardial infarction: the CASTUO study.
CORRESPONDENCIA ¿Son las escalas de riesgo CHADS 2 y CHA 2 DS 2 VASc instrumentos útiles para ini... more CORRESPONDENCIA ¿Son las escalas de riesgo CHADS 2 y CHA 2 DS 2 VASc instrumentos útiles para iniciar medicación anticoagulante? Are the CHADS 2 and CHA 2 DS 2-VASc scales useful instruments to initiate anticoagulant medication? La escala de riesgo de enfermedad tromboembólica CHADS 2 se ha empleado en pacientes con fibrilación auricular (FA) no valvular para estimar el riesgo de ictus y, en consecuencia, la indicación de tratamiento anticoagulante (ACO) 1. En el año 2010 se ha propuesto la escala CHA 2 DS 2 VASc en un intento de mejorar la predicción del riesgo de ictus en poblaciones Tabla 1 Características de los enfermos con infarto de miocardio, insuficiencia cardiaca e ictus isquémico (ictus). Se indica el número de pacientes en fibrilación auricular que deberían recibir tratamiento anticoagulante según la puntuación de las escalas CHADS 2 y CHA 2 DS 2 VASc Infarto de miocardio (n= 2.157) Insuficiencia cardiaca (n = 2.138) Ictus (n = 2.247) Número con fibrilación auricular 233 (10,8%) 936 (43,8) 531 (23,6) Varones 134 (57,5) 436 (46,6) 212 (39,9) Edad (± DE) 76,4 (± 10,4) 76,9 (± 9,9) 77,9 (± 7,9) Infarto de miocardio, (%) 233 (100) 72 (7,7) 26 (4,9) Tabaquismo activo, (%) 15 (6,4) 46 (4,9) 29 (5,5) Ictus previo, (%) 49 (21) 119 (12,7) 97 (18,3) Enfermedad arterial periférica, (%) 11 (4,7) 24 (2,6) 26 (4,9) Insuficiencia cardiaca, (%) 76 (32,6) 936 (100) 61 (11,5) Insuficiencia renal crónica, (%) 25 (10,7) 152 (16,2) 30 (5,6) EPOC a , (%) 40 (17,2) 283 (30,2) 71 (13,4) Hipertensión arterial, (%) 213 (91,4) 831 (88,8) 444 (83,6) Diabetes mellitus, (%) 94 (40,3) 366 (39,1) 167 (31,5) Hipercolesterolemia, (%) 105 (45,1) 225 (27,2) 169 (31,8) * Autor para correspondencia.
Enfermedades cardiovasculares; Insuficiencia cardiaca; Mortalidad Resumen Antecedentes y objetivo... more Enfermedades cardiovasculares; Insuficiencia cardiaca; Mortalidad Resumen Antecedentes y objetivos: La insuficiencia cardiaca es la causante del mayor gasto sanitario en hospitalización y la tercera causa de mortalidad cardiovascular. Fue nuestro objetivo determinar la evolución de las características clínicas, y los factores relacionados con el pronóstico en pacientes ingresados por insuficiencia cardiaca en un área de salud de Extremadura durante 10 años. Pacientes y métodos: Estudio observacional, retrospectivo y unicéntrico en pacientes consecutivos ingresados por insuficiencia cardiaca descompensada en un Hospital General de la provincia de Badajoz en el período 2000/2009. Resultados: Se incluyeron 2.220 pacientes con una edad media de 76,3 (DE ± 10,1) años, 54% mujeres. Estratificados en 4 períodos de 30 meses, se observó: un significativo incremento de los pacientes mayores de 75 años (55 al 71%; p < 0,001) y al alta una mayor prescripción de bloqueadores beta (12 al 34%; p < 0,001), estatinas (8 al 31%; p < 0,001), y anticoagulantes orales (13 al 25%; p < 0,001). La mortalidad intrahospitalaria disminuyó del 13 al 8% (p < 0,01) y al año del 30 al 23% (p < 0,01). Fueron predictores independientes de mortalidad al año la edad (HR = 1,04 [IC del 95%: 1,02-1,05]), la diabetes (HR = 1,35 [IC del 95%: 1,11-1,66]) y la insuficiencia renal (HR = 1,49 [IC del 95%: 1,18-1,87]). Conclusiones: La mortalidad ha disminuido significativamente en la década a pesar del incremento de la edad. La edad, la diabetes y la insuficiencia renal crónica resultaron predictores independientes de mortalidad al año. La anticoagulación resultó protectora.
Background The influence of socioeconomic development is often disregarded in epidemiological stu... more Background The influence of socioeconomic development is often disregarded in epidemiological studies into the prevalence of cardiovascular risk factors. Aim To analyse the relationship between major cardiovascular risk factors and socioeconomic indicators. Design and setting Cross-sectional, population-wide study in primary care practices in the health area of Don Benito
ABSTRACT We show the results of a retrospective study designed to assess the features of transien... more ABSTRACT We show the results of a retrospective study designed to assess the features of transient job disability (TJD) episodes of workers from two groups (clerks and nurses) from an urban health basiczonewith 24,536 inhabitants, out of which 6,009 were active workers registered in social security databases. Population pyramid and job distribution in active workers were obtained from a random sample including 5% of the active population, out of which 17% were clerks and 5.54% nurses. There were 1098 TJD episodes in 1990; 32.4% of them involved clerks and 8,.3% nurses. The mean length of episodes was 28.2 days in nurses and 27.8 days among clerks, compared to 32.4 days in the active population. These differences remained (p&lt; 0.001) even after excluding TJD episodes of pregnant women, in whose case the mean length of episodes involving male or female workers was the same. The percentage of TJD episodes was higher among female nurses and clerks, than among the whole female population. Influenza was responsible for 20.5% of TJD in clerks against 14.3% among nurses and 14.8% in the whole active population. We conclude that, in the groups studied, the rate of job absenteeism was higher than in the whole polulation, and higher in female than in males. However, in the whole population, there were no differences in TJD rates between males and females. We discuss that several factors other than illness may explain the differences among groups.
Alcohol has been associated with a lower risk of developing cardiovascular disease. It has been o... more Alcohol has been associated with a lower risk of developing cardiovascular disease. It has been our objective to determine the prevalence of use of alcohol and its association with the presence of cardiovascular risk factors (CRF). Cross-sectional study. Don Benito-Villanueva de la Serena health area (Badajoz). We selected a random sample of 25 to 79 year olds, representative of the population. We collected a survey about the history of cardiovascular risk factors and alcohol consumption in the previous seven days. We measured blood pressure and a fasting blood sample was obtained. The association of alcohol consumption with the different CRF was studied by multivariate analysis, adjusting for different variables. A total of 2833 subjects participated, with a mean age 51.2 (SD 14.7) years and 46.5% males. We detected 36.1% (95% CI 34.4 to 37.9) of alcohol consumers. The overall prevalence and consumption medium or high risk was 63.2% and 15.2% in men, and 12.6% and 1.5% in women, respectively. In men, consumption of medium-high risk was associated with hypercholesterolemia, hypertension and smoking. In women, low-risk consumption was associated with a lower prevalence of obesity and hypertension and higher smoking. We found a lower prevalence of alcohol use, especially in women, compared to the Spanish national average. The consumption of medium-high risk mainly affects men and is associated with increased cardiovascular risk. In women at low risk consumption is associated with a lower prevalence of certain CRF and increased smoking.
MESEAS (MEjora SErvicio ASistencial) ha demostrado la viabilidad para integrar las TIC en los ser... more MESEAS (MEjora SErvicio ASistencial) ha demostrado la viabilidad para integrar las TIC en los servicios asistenciales de Salud, haciendo partícipes a facultativos y pacientes, reduciendo así la brecha digital que tienen lo servicios sanitarios en su labor de ayudar a los ciudadanos. La solución planteada por MESEAS implementa e integra un conjunto de sensores biomédicos que realizan la monitorización a distancia
The prevalence and significance of microalbuminuria in hypertensive patients with impaired fastin... more The prevalence and significance of microalbuminuria in hypertensive patients with impaired fasting glucose (IFG) has received very little attention. A total of 10,320 hypertensive patients who attended primary care centers were enrolled in this study, and the final analysis was done in 7625 patients: 1459 without IFG (plasma glucose <100 mg/dl), 3010 with IFG (plasma glucose >100 mg/dl and <126 mg/dl), and 3156 with type 2 diabetes (plasma glucose >126 mg/dl). Microalbuminuria was determined using the Micro Albustix reactive strip from Bayer (high urinary albumin excretion [UAE]: Albumin/creatinine ratio >3.4 mg/mmol). The proportion of patients with high UAE was 39.4, 48.3, and 65.6%, respectively, in the three groups (P < 0.01 for the trend). The differences in UAE between the group with IFG and the group with normal fasting glucose persisted after adjustment for age, gender, systolic BP, fasting plasma glucose, and cardiovascular comorbidity (odds ratio 1.74; 95% confidence interval 1.08 to 2.80). Hypertensive patients with IFG and high UAE showed a higher prevalence of ischemic heart disease, cardiac insufficiency, left ventricular hypertrophy, atrial fibrillation, and renal insufficiency than the group with normal UAE. Global prevalence of cardiovascular conditions was 30.4% in the group with high UAE compared with 21.4% in the group with normal UAE (odds ratio 1.60; 95% confidence interval 1.31 to 1.95). It is concluded that almost half of hypertensive patients with IFG have high UAE and a higher prevalence of associated cardiovascular involvement and renal insufficiency.
European review for medical and pharmacological sciences
OBJECTIVES: To evaluate the relationship chronic renal failure (CFR) defined through HUGE (hemato... more OBJECTIVES: To evaluate the relationship chronic renal failure (CFR) defined through HUGE (hematocrit, urea and gender) formula score and the patient´s cardiovascular risk measured through cardiovascular disease antecedents such are ischemic cardiopathy, cerebrovascular disease and peripheral arterial disease.
To estimate the prevalence, detection, treatment and degree of control of cardiovascular risk fac... more To estimate the prevalence, detection, treatment and degree of control of cardiovascular risk factors in Extremadura. Cross-sectional study. Population study in Don Benito-Villanueva de la Serena health area (Badajoz). A random sample of the people between 25 and 79 years, who lived in this area, was selected. History of cardiovascular risk factors and its treatment were obtained by questionnaire. Blood pressure and blood sample were obtained for all participants. We calculated the prevalence of each variable standardized for age and gender for the population of Extremadura. Of the 3521 eligible, 2833 (80.5%) participants were included, mean age 51.2 years, male 46.5%. Adjusted prevalence of current smoking in men: 40.5% (37.8-43.2), hypertension 39.5% (37.3-41.7), hypercholesterolemia, 37.9% (35.4-40.4), obesity 36.5% (33.9-39.1), diabetes 13.7% (12.1-15.4). Adjusted prevalence of hypercholesterolemia in women: 35,0% (32.9-37.2), hypertension 33,0% (31.3-34.7), obesity 30.7% (28.6-...
Distintas fuentes coinciden en situar a la insuficiencia cardiaca (IC) como uno de los problemas ... more Distintas fuentes coinciden en situar a la insuficiencia cardiaca (IC) como uno de los problemas sanitarios mas graves a los que se enfrentan los distintos sistemas sanitarios de los paises occidentales en la actualidad y mas aun en las proximas decadas. Asi como la mortalidad (tasas ajustadas por edad) debida a la cardiopatia isquemica y a los accidentes cerebrovasculares, se encuentra en descenso desde hace mas de 25 anos, la mortalidad debida a IC va aumentando. La IC es la tercera causa de muerte por enfermedad cardiovascular en Espana, causando cerca del 25% de fallecimientos por esta causa (tras el ictus y la cardiopatia isquemica). Por todo ello, la IC es un importante problema de salud publica en Espana, al igual que en otros paises desarrollados. Ademas, la magnitud del problema crecera en los proximos anos por el progresivo envejecimiento de la poblacion. Se aprecia como mas de 8 millones de espanoles sobrepasaran los 65 anos en el 2021. Solo por este motivo, la prevalenci...
Conclusiones: Este estudio demuestra de una forma indirecta los cambios epidemiológicos que se es... more Conclusiones: Este estudio demuestra de una forma indirecta los cambios epidemiológicos que se están produciendo en el ictus. Existe suficiente evidencia que indica un cambio epidemiológico al aumentar la tasa de hospitalizaciones en adultos jóvenes.
Revista espanola de cardiologia (English ed.), Jan 18, 2017
Atrial fibrillation (AF) is an independent risk factor for mortality in several diseases. However... more Atrial fibrillation (AF) is an independent risk factor for mortality in several diseases. However, data published in acute decompensated heart failure (DHF) are contradictory. Our objective was to investigate the impact of AF on mortality in patients admitted to hospital for DHF compared with those admitted for other reasons. This retrospective cohort study included all patients admitted to hospital within a 10-year period due to DHF, acute myocardial infarction (AMI), or ischemic stroke (IS), with a median follow-up of 6.2 years. We included 6613 patients (74 ± 11 years; 54.6% male); 2177 with AMI, 2208 with DHF, and 2228 with IS. Crude postdischarge mortality was higher in patients with AF hospitalized for AMI (incident rate ratio, 2.48; P < .001) and IS (incident rate ratio, 1.84; P < .001) than in those without AF. No differences were found in patients with DHF (incident rate ratio, 0.90; P = .12). In adjusted models, AF was not an independent predictor of in-hospital mort...
Sánchez L, et al. Risk factors and therapeutic coverage at 6 years in patients with previous myoc... more Sánchez L, et al. Risk factors and therapeutic coverage at 6 years in patients with previous myocardial infarction: the CASTUO study.
CORRESPONDENCIA ¿Son las escalas de riesgo CHADS 2 y CHA 2 DS 2 VASc instrumentos útiles para ini... more CORRESPONDENCIA ¿Son las escalas de riesgo CHADS 2 y CHA 2 DS 2 VASc instrumentos útiles para iniciar medicación anticoagulante? Are the CHADS 2 and CHA 2 DS 2-VASc scales useful instruments to initiate anticoagulant medication? La escala de riesgo de enfermedad tromboembólica CHADS 2 se ha empleado en pacientes con fibrilación auricular (FA) no valvular para estimar el riesgo de ictus y, en consecuencia, la indicación de tratamiento anticoagulante (ACO) 1. En el año 2010 se ha propuesto la escala CHA 2 DS 2 VASc en un intento de mejorar la predicción del riesgo de ictus en poblaciones Tabla 1 Características de los enfermos con infarto de miocardio, insuficiencia cardiaca e ictus isquémico (ictus). Se indica el número de pacientes en fibrilación auricular que deberían recibir tratamiento anticoagulante según la puntuación de las escalas CHADS 2 y CHA 2 DS 2 VASc Infarto de miocardio (n= 2.157) Insuficiencia cardiaca (n = 2.138) Ictus (n = 2.247) Número con fibrilación auricular 233 (10,8%) 936 (43,8) 531 (23,6) Varones 134 (57,5) 436 (46,6) 212 (39,9) Edad (± DE) 76,4 (± 10,4) 76,9 (± 9,9) 77,9 (± 7,9) Infarto de miocardio, (%) 233 (100) 72 (7,7) 26 (4,9) Tabaquismo activo, (%) 15 (6,4) 46 (4,9) 29 (5,5) Ictus previo, (%) 49 (21) 119 (12,7) 97 (18,3) Enfermedad arterial periférica, (%) 11 (4,7) 24 (2,6) 26 (4,9) Insuficiencia cardiaca, (%) 76 (32,6) 936 (100) 61 (11,5) Insuficiencia renal crónica, (%) 25 (10,7) 152 (16,2) 30 (5,6) EPOC a , (%) 40 (17,2) 283 (30,2) 71 (13,4) Hipertensión arterial, (%) 213 (91,4) 831 (88,8) 444 (83,6) Diabetes mellitus, (%) 94 (40,3) 366 (39,1) 167 (31,5) Hipercolesterolemia, (%) 105 (45,1) 225 (27,2) 169 (31,8) * Autor para correspondencia.
Enfermedades cardiovasculares; Insuficiencia cardiaca; Mortalidad Resumen Antecedentes y objetivo... more Enfermedades cardiovasculares; Insuficiencia cardiaca; Mortalidad Resumen Antecedentes y objetivos: La insuficiencia cardiaca es la causante del mayor gasto sanitario en hospitalización y la tercera causa de mortalidad cardiovascular. Fue nuestro objetivo determinar la evolución de las características clínicas, y los factores relacionados con el pronóstico en pacientes ingresados por insuficiencia cardiaca en un área de salud de Extremadura durante 10 años. Pacientes y métodos: Estudio observacional, retrospectivo y unicéntrico en pacientes consecutivos ingresados por insuficiencia cardiaca descompensada en un Hospital General de la provincia de Badajoz en el período 2000/2009. Resultados: Se incluyeron 2.220 pacientes con una edad media de 76,3 (DE ± 10,1) años, 54% mujeres. Estratificados en 4 períodos de 30 meses, se observó: un significativo incremento de los pacientes mayores de 75 años (55 al 71%; p < 0,001) y al alta una mayor prescripción de bloqueadores beta (12 al 34%; p < 0,001), estatinas (8 al 31%; p < 0,001), y anticoagulantes orales (13 al 25%; p < 0,001). La mortalidad intrahospitalaria disminuyó del 13 al 8% (p < 0,01) y al año del 30 al 23% (p < 0,01). Fueron predictores independientes de mortalidad al año la edad (HR = 1,04 [IC del 95%: 1,02-1,05]), la diabetes (HR = 1,35 [IC del 95%: 1,11-1,66]) y la insuficiencia renal (HR = 1,49 [IC del 95%: 1,18-1,87]). Conclusiones: La mortalidad ha disminuido significativamente en la década a pesar del incremento de la edad. La edad, la diabetes y la insuficiencia renal crónica resultaron predictores independientes de mortalidad al año. La anticoagulación resultó protectora.
Background The influence of socioeconomic development is often disregarded in epidemiological stu... more Background The influence of socioeconomic development is often disregarded in epidemiological studies into the prevalence of cardiovascular risk factors. Aim To analyse the relationship between major cardiovascular risk factors and socioeconomic indicators. Design and setting Cross-sectional, population-wide study in primary care practices in the health area of Don Benito
ABSTRACT We show the results of a retrospective study designed to assess the features of transien... more ABSTRACT We show the results of a retrospective study designed to assess the features of transient job disability (TJD) episodes of workers from two groups (clerks and nurses) from an urban health basiczonewith 24,536 inhabitants, out of which 6,009 were active workers registered in social security databases. Population pyramid and job distribution in active workers were obtained from a random sample including 5% of the active population, out of which 17% were clerks and 5.54% nurses. There were 1098 TJD episodes in 1990; 32.4% of them involved clerks and 8,.3% nurses. The mean length of episodes was 28.2 days in nurses and 27.8 days among clerks, compared to 32.4 days in the active population. These differences remained (p&lt; 0.001) even after excluding TJD episodes of pregnant women, in whose case the mean length of episodes involving male or female workers was the same. The percentage of TJD episodes was higher among female nurses and clerks, than among the whole female population. Influenza was responsible for 20.5% of TJD in clerks against 14.3% among nurses and 14.8% in the whole active population. We conclude that, in the groups studied, the rate of job absenteeism was higher than in the whole polulation, and higher in female than in males. However, in the whole population, there were no differences in TJD rates between males and females. We discuss that several factors other than illness may explain the differences among groups.
Alcohol has been associated with a lower risk of developing cardiovascular disease. It has been o... more Alcohol has been associated with a lower risk of developing cardiovascular disease. It has been our objective to determine the prevalence of use of alcohol and its association with the presence of cardiovascular risk factors (CRF). Cross-sectional study. Don Benito-Villanueva de la Serena health area (Badajoz). We selected a random sample of 25 to 79 year olds, representative of the population. We collected a survey about the history of cardiovascular risk factors and alcohol consumption in the previous seven days. We measured blood pressure and a fasting blood sample was obtained. The association of alcohol consumption with the different CRF was studied by multivariate analysis, adjusting for different variables. A total of 2833 subjects participated, with a mean age 51.2 (SD 14.7) years and 46.5% males. We detected 36.1% (95% CI 34.4 to 37.9) of alcohol consumers. The overall prevalence and consumption medium or high risk was 63.2% and 15.2% in men, and 12.6% and 1.5% in women, respectively. In men, consumption of medium-high risk was associated with hypercholesterolemia, hypertension and smoking. In women, low-risk consumption was associated with a lower prevalence of obesity and hypertension and higher smoking. We found a lower prevalence of alcohol use, especially in women, compared to the Spanish national average. The consumption of medium-high risk mainly affects men and is associated with increased cardiovascular risk. In women at low risk consumption is associated with a lower prevalence of certain CRF and increased smoking.
MESEAS (MEjora SErvicio ASistencial) ha demostrado la viabilidad para integrar las TIC en los ser... more MESEAS (MEjora SErvicio ASistencial) ha demostrado la viabilidad para integrar las TIC en los servicios asistenciales de Salud, haciendo partícipes a facultativos y pacientes, reduciendo así la brecha digital que tienen lo servicios sanitarios en su labor de ayudar a los ciudadanos. La solución planteada por MESEAS implementa e integra un conjunto de sensores biomédicos que realizan la monitorización a distancia
The prevalence and significance of microalbuminuria in hypertensive patients with impaired fastin... more The prevalence and significance of microalbuminuria in hypertensive patients with impaired fasting glucose (IFG) has received very little attention. A total of 10,320 hypertensive patients who attended primary care centers were enrolled in this study, and the final analysis was done in 7625 patients: 1459 without IFG (plasma glucose <100 mg/dl), 3010 with IFG (plasma glucose >100 mg/dl and <126 mg/dl), and 3156 with type 2 diabetes (plasma glucose >126 mg/dl). Microalbuminuria was determined using the Micro Albustix reactive strip from Bayer (high urinary albumin excretion [UAE]: Albumin/creatinine ratio >3.4 mg/mmol). The proportion of patients with high UAE was 39.4, 48.3, and 65.6%, respectively, in the three groups (P < 0.01 for the trend). The differences in UAE between the group with IFG and the group with normal fasting glucose persisted after adjustment for age, gender, systolic BP, fasting plasma glucose, and cardiovascular comorbidity (odds ratio 1.74; 95% confidence interval 1.08 to 2.80). Hypertensive patients with IFG and high UAE showed a higher prevalence of ischemic heart disease, cardiac insufficiency, left ventricular hypertrophy, atrial fibrillation, and renal insufficiency than the group with normal UAE. Global prevalence of cardiovascular conditions was 30.4% in the group with high UAE compared with 21.4% in the group with normal UAE (odds ratio 1.60; 95% confidence interval 1.31 to 1.95). It is concluded that almost half of hypertensive patients with IFG have high UAE and a higher prevalence of associated cardiovascular involvement and renal insufficiency.
European review for medical and pharmacological sciences
OBJECTIVES: To evaluate the relationship chronic renal failure (CFR) defined through HUGE (hemato... more OBJECTIVES: To evaluate the relationship chronic renal failure (CFR) defined through HUGE (hematocrit, urea and gender) formula score and the patient´s cardiovascular risk measured through cardiovascular disease antecedents such are ischemic cardiopathy, cerebrovascular disease and peripheral arterial disease.
To estimate the prevalence, detection, treatment and degree of control of cardiovascular risk fac... more To estimate the prevalence, detection, treatment and degree of control of cardiovascular risk factors in Extremadura. Cross-sectional study. Population study in Don Benito-Villanueva de la Serena health area (Badajoz). A random sample of the people between 25 and 79 years, who lived in this area, was selected. History of cardiovascular risk factors and its treatment were obtained by questionnaire. Blood pressure and blood sample were obtained for all participants. We calculated the prevalence of each variable standardized for age and gender for the population of Extremadura. Of the 3521 eligible, 2833 (80.5%) participants were included, mean age 51.2 years, male 46.5%. Adjusted prevalence of current smoking in men: 40.5% (37.8-43.2), hypertension 39.5% (37.3-41.7), hypercholesterolemia, 37.9% (35.4-40.4), obesity 36.5% (33.9-39.1), diabetes 13.7% (12.1-15.4). Adjusted prevalence of hypercholesterolemia in women: 35,0% (32.9-37.2), hypertension 33,0% (31.3-34.7), obesity 30.7% (28.6-...
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Papers by Luis Lozano