A theoretical cardiac resynchronization therapy method to augment ventricular contraction using polymer-based actuators and mitral regurgitation reduction with devices over left ventricular endocardial pacing wire--an in-vitro study
The Journal of invasive cardiology, 2013
To investigate a potential cardiac resynchronization method using high force density actuators an... more To investigate a potential cardiac resynchronization method using high force density actuators and mitral regurgitation (MR) reduction devices. An 8-cm long, 0.4-mm thick, and 2-mm wide polymeric actuator strip was attached to the right ventricular (RV) pacemaker lead 4.0 cm from the edge of the leads, and 035 wire and step-up voltages (2-9 V) were given. Deformation of the pacemaker lead with polymer was studied under cine-fluoroscopy in the air and immersing it in 0.9% saline. Cantilever function was assessed by the addition of gold rings. The left ventricular (LV) lead was reinforced with dual polymer and a side branching 035 wire Y-attachment and studied. A novel nitinol-based Gore-Tex device and polymer-based technology was developed and positioned abutting the mitral valves, and was evaluated in sheep heart preparations by cine-fluoroscopy. The mean deformation at 9 V for the LV leads, RV leads, and 035 wires was 3.5 ± 0.2 mm, 1.1 ± 0.1 mm, and 1.4 ± 0.1 mm, respectively, and ...
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Papers by Luis Guerrero