Novel upconversion nanocomposites with nanoporous structure were presented in this paper. Silica-... more Novel upconversion nanocomposites with nanoporous structure were presented in this paper. Silica-coated cubic NaYF4:Yb3+, Tm3+ nanoparticles were first prepared. After annealing, monodisperse cubic/hexagonal mixed phases NaYF4:Yb3+, Tm3+@SiO2 nanoparticles were obtained, and the NaYF4:Yb3+, Tm3+ cores became nanoporous. To the best of our knowledge, the nanoporous structure in NaYF4:Yb3+, Tm3+@SiO2 nanocomposites was observed for the first time. They demonstrate increased upconversion emission compared with unannealed dense NaYF4:Yb3+, Tm3+ nanoparticles due to the appearance of the hexagonal NaYF4:Yb3+, Tm3+. The silica shell not only makes the nanocomposites possess bio-affinity but also protects the NaYF4:Yb3+, Tm3+ cores from aggregating and growing up. Thus the upconversion, nanoporous and bio-affinity properties were combined into one single nanoparticle. The nanocomposites have been characterized by X-ray diffraction (XRD), field-emission scanning electron microscopy (FE-SEM)...
Extrinsic Fabry-Perot interferometer (EFPI) and fiber Bragg grating (FBG) sensors can construct o... more Extrinsic Fabry-Perot interferometer (EFPI) and fiber Bragg grating (FBG) sensors can construct one of most promising sensor group for simultaneous temperature and strain measurement in structure health monitoring. The demodulation of the sensor group is critical. Here, a parallel demodulation system used for the goal is presented, which is based on a Michelson interferometer and combines the method of low
Purpose: To investigate the efficiency of lysozyme and albumin removal from silicone hydrogel and... more Purpose: To investigate the efficiency of lysozyme and albumin removal from silicone hydrogel and conventional contact lenses, using a polyhexamethylene biguanide multipurpose solution (MPS) in a soaking or rubbing/soaking application and a hydrogen peroxide system (H2O2). Methods: Etafilcon A, lotrafilcon B and balafilcon A materials were incubated in protein solutions for up to 14 days. Lenses were either placed in
The spleen combines the innate and adaptive immune systems in a uniquely organized way. The excis... more The spleen combines the innate and adaptive immune systems in a uniquely organized way. The excision of spleen will induce many complications, especially the increased susceptibility to infections. Recent research shows that besides playing roles during the immune responses, the spleen is also an important organ during immunoregulation, which is different from other secondary lymphoid organs. This unique function is mainly realized by modulating cell migration and proliferation in the spleen. This review provides a better understanding of the functions of this complex organ gained from recent studies.
Proceedings of 2011 International Conference on Electronics and Optoelectronics, 2011
A new method was proposed to measure the surface deformation, where the optics is irradiated by a... more A new method was proposed to measure the surface deformation, where the optics is irradiated by a high power laser when they are measured with ZYGO interferometer. The fiber with output shaper was used to transmit the laser. With this simple and convenient method, measuring k9, fused silica and antireflection coated silica windows, where a power of 200W doubled YAG
ABSTRACT Core–shell structured YVO4:Eu3+@SiO2 nanocomposite particles were synthesized using a on... more ABSTRACT Core–shell structured YVO4:Eu3+@SiO2 nanocomposite particles were synthesized using a one-pot reverse microemulsion method and characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM), UV absorption spectra, and photoluminescent spectra. The nanocomposite particles are well-dispersed and about 20 nm in average size. The synthesis method is of one-pot, simplifying the preparation of this kind of core–shell structured nanocomposites. The formation process of these nanocomposite particles is suggested and the photoluminescence properties of them are studied and compared with those of uncoated YVO4:Eu3+ sample.
a b s t r a c t A novel method using particle-packing technique to fabricate capillary electropho... more a b s t r a c t A novel method using particle-packing technique to fabricate capillary electrophoresis (CE)-based immobilized enzyme reactor (IMER) was accomplished by utilizing perfusive silica single particles as the frits and large-pore beads as the enzyme supports. The fabrication procedure is rapid and simple; the length and enzyme loading amount of the CE-IMERs could be easily adjusted. Performance and feasibility of the CE-IMERs were investigated using on-line trypsin digestion as the model enzyme reaction. High reproducible on-line enzyme assay was demonstrated with RSD less than 4.1% and 3.8% for peak area and migration time of the substrate and product over 100 consecutive runs, respectively. The enzyme can still maintain the activity for at least 10 days, indicating remarkably stability of the CE-IMERs. The CE-IMERs were successfully applied for accurate analysis of trypsin inhibition as well as on-line digestion of standard proteins (myoglobin and BSA). The present method provides a new interesting alternative to open-tubular and monolithic CE-IMERs, thus expands the application of the CE technique for on-line enzyme assay and analysis and characterization of peptides and proteins.
The complete cDNA and deduced amino-acid sequences of ribosomal proteins L34 (AmphiL34) and S29 (... more The complete cDNA and deduced amino-acid sequences of ribosomal proteins L34 (AmphiL34) and S29 (AmphiS29) from the amphioxus Branchiostoma belcheri tsingtauense were identified in this study. The AmphiL34 cDNA is 435 nucleotides in length and encodes a 118 amino-acid protein with calculated molecular mass of 13.6 kDa. It shares 53.6-67.5% amino-acid sequence identity with its eukaryotic counterparts including human, mouse, rat, pig, frog, catfish, fruit fly, mosquito, armyworm, nematode and yeast. The AmphiS29 cDNA comprises 453 nucleotides and codes for a 56 amino-acid protein with a calculated molecular mass of 6.6 kDa. It shows 66.1-78.6% amino-acid sequence identity to eukaryotic S29 proteins from human, mouse, rat, pig, zebrafish, seahorse, fruit fly, nematode, sea hare and yeast. AmphiL34 contains a putative nucleolar localization signal, while AmphiS29 has a zinc finger-like domain. A phylogenetic tree deduced from the conserved sequences of AmphiL34 and AmphiS29 and other k...
AIM: To investigate the relationship between H pylori in- fection and PTEN, cyclinE expression in... more AIM: To investigate the relationship between H pylori in- fection and PTEN, cyclinE expression in gastric cancer and adjacent mucosal tissues, and to study the possible mecha- nism of H pylori in gastric carcinogenesis. METHODS: Both rapid urease and pathological test were used to examine H pylori in 59 cases of specimen. The expression of PTEN and cyclinE in gastric
We report here theoretical and experimental studies on the sequential diffusion injection (SDI) f... more We report here theoretical and experimental studies on the sequential diffusion injection (SDI) for CE analysis. Based on the Fick's second law, a theoretical model for two-dimensional (2-D) diffusion has been developed for our SDI system. The 2-D diffusion model has been demonstrated via systematic experimental studies using standard nicotinamide adenine dinucleotide (NADH) as the model analyte. The results show that the dependence of the NADH peak area (corresponding to the injection amount) on the initial sample concentration, the injection time or the capillary-gap distance is consistent with the deduction of the 2-D diffusion model. It is indicated that the 2-D diffusion, both in longitudinal and transverse directions of the capillary, enhances the injection efficiency in comparison to classical concentration diffusion on the plane interface, and improves the accuracy of the sequential injection without any physical disturbance of the capillary inlet. With the insight under...
Through the functionalization of multiwalled carbon nanotubes (MWCNTs) by 0,0(-diallylbisphenol A... more Through the functionalization of multiwalled carbon nanotubes (MWCNTs) by 0,0(-diallylbisphenol A (DBA), the interface situation between MWCNTs and bismaleimide (BMI) was improved, as detected by scanning electron microscope (SEM) and dynamic mechanical analysis (DMA). The improved interface situation was considered to be the main reason for the huge increased microhardness value and greatly improved the microtribological property of MWCNTs/BMI composites. Besides, the wear mechanism for the composite was also believed to be related to the interfacial situation. The rough wavelike worn surface of pure BMI resin is attributed to its poor load capacity. The smoother waterfall-shape worn surface of MWCNTs/BMI is related to the interface formed by the addition of MWCNTs while the ultrasmooth worn surface of DBA modified MWCNTs/BMI is due to the greatly improved interfacial interaction of the composite.
Abstract The reaction of naphthalene with the OH radical was studied in a 10 m3 smog chamber. Rea... more Abstract The reaction of naphthalene with the OH radical was studied in a 10 m3 smog chamber. Reaction products identified include 1, 2-benzenedicarboxaldehyde, phthalic anhydride, phthalic acid, 1 (3H)-isobenzofuranone, 1, 4-naphthalenedione, 4-methyl-2H-1 ...
Background: Centromere protein A (CENP-A) plays important roles in cell-cycle regulation and gene... more Background: Centromere protein A (CENP-A) plays important roles in cell-cycle regulation and genetic stability. Herein, we aimed to investigate its expression pattern, clinical significance, and biological function in hepatocellular carcinoma (HCC).
Introduction -We report a rapid and accurate method to determine the natural occurrence of aflato... more Introduction -We report a rapid and accurate method to determine the natural occurrence of aflatoxins (AFs) B1, B2, G1 and G2 in medicinal herbs and the analysis of 174 commercial samples by this method. Objective -The aim of the present work is to examine the occurrence of the aflatoxins B1, B2, G1 and G2 in common medicinal herbs. Methodology -The AFs were extracted, purified by immunoaffinity column and analysed by high-performance liquid chromatography-tandem quadrupole mass spectrometry with electrospray ionisation (HPLC-MS/MS). Results -The AFs can be separated within 6 min using an Agilent XDB C 18 -column. The target analyte AFB1 could be detected at 0.14 mg/kg. A good linear relationship was found for AFG1 and AFB1 in 1-100 pg and AFG2 and AFB2 in 0.8-30 pg (r > 0.9995). The analyte recovery under three different spiking levels was 64-100% with the relative standard deviations (RSD) below 8.19%. Conclusion -This simple and accurate method effectively eliminates false positive detection and can be used to determine the AFs in medicinal herbs to control product quality. We found that in the 174 samples tested, 27 were contaminated with AFs. The incidences of AFB1, AFB2, AFG1 and AFG2 in the samples tested were 15.52%, 14.37%, 6.32% and 2.30%, respectively. We proposed 10 mg/kg total AFs and 5 mg/kg AFB1 as the reasonable maximum limits (ML) in medicinal herbs, and there are 10 samples (5.71% occurrence) in our test that exceeded this proposed limit. a High level: 10 ngÁmL -1 AFB1, 10 ngÁmL -1 AFG1, 3.0 ngÁmL -1 AFB2, 3.0 ngÁmL -1 AFG2. b Medium level: 2 ngÁmL -1 AFB1, 2 ngÁmL -1 AFG1, 0.6 ngÁmL -1 AFB2, 0.6 ngÁmL -1 AFG2. c Low level: 0.5 ngÁmL -1 AFB1, 0.5 ngÁmL -1 AFG1, 0.15 ngÁmL -1 AFB2, 0.15 ngÁmL -1 AFG2. Figure 3. MRM mass spectrum of tomentose pummelo peel: 1, reference substances comprising a mixture of aflatoxins; 2, tomentose pummelo peel.
Physica E: Low-dimensional Systems and Nanostructures, 2013
ABSTRACT By using nonequilibrium Green's function method, we study the phonon transport p... more ABSTRACT By using nonequilibrium Green's function method, we study the phonon transport properties in S-shaped graphene nano-junctions (GNJs). Interesting transmission phenomenon is found. The transmission spectrum of low frequency phonon shows forbidden frequency band, by changing the width W2 of the S-shaped GNJs. These low frequency forbidden bands are sensitive to their periodic geometric shape of GNJs. These thermal transport phenomena can be explained by analyzing the phonon transmission coefficient. This paper illustrates the thermal transport mechanisms in the different S-shaped GNJs, and the results could provide significant physical models and theoretical validity in designing the thermal devices based on the GNJs.
The aim of this study was to explore the usefulness of multiple excitation autofluorescence (AF) ... more The aim of this study was to explore the usefulness of multiple excitation autofluorescence (AF) and a spectral feature-based pattern recognition in classification of colon tissues. Under four different excitation wavelengths (337, 375, 405 and 460 nm), AF spectra of freshly excised normal and adenocarcinoma colon tissues were measured. Pattern recognition method including features extraction, data reduction using principal component analysis (PCA) and Fisher's discriminant analysis (FDA) were performed for classification. There was a significantly difference between spectral patterns of normal and adenocarcinoma tissues. Compared with the other three excitation wavelengths, the AF spectra obtained under 337 nm excitation provided more diagnostic information, but also more sensitive to the trivial change resulted from neoplastic transformation. For discriminating normal from adenocarcinoma tissues, the sensitivity, specificity and accuracy using 337 nm excitation in the present study were 88.9%, 80.0% and 83.9%, respectively. Compared these values with those determined from multispectral data analysis, our findings indicate that the latter has higher specificity while maintaining the same sensitivity (sensitivity 88.9% vs. 88.9%, specificity 91.4% vs. 80.0%, and accuracy 90.3% vs. 83.9%). This study suggests that the pattern recognition of the multiple excitation AF spectra is an effective algorithm for improving the diagnostic accuracy of adenocarcinoma.
The aim of this study was to compare the sensitivity of hematoporphyrin monomethyl ether (HMME)-m... more The aim of this study was to compare the sensitivity of hematoporphyrin monomethyl ether (HMME)-mediated PDT in the Epstein-Barr virus (EBV) positive and negative human nasopharyngeal carcinoma (NPC) cells. The intracellular uptake of HMME in C666-1 (EBV+) and CNE2 (EBV-) cells was quantitatively determined after incubating with different concentration of HMME. The subcellular localization of HMME was examined under a laser scanning fluorescence microscopy. The survival rate of C666-1 and CNE2 cells after HMME PDT was evaluated with clonogenic assay. The EBV- CNE2 cells showed higher intracellular uptake of HMME and lower survival rate than EBV+ C666-1 cells. There was no significant difference in terms of subcellular localization of HMME between C666-1 and CNE2 cells. The sensitivity of EBV- CNE2 cells to HMME-mediated PDT was significantly higher than that of EBV+ C666-1 cells. The intracellular uptake of HMME plays a key role in determining the PDT sensitivity.
A parallel demodulation system for extrinsic Fabry-Perot interferometer (EFPI) and fiber Bragg gr... more A parallel demodulation system for extrinsic Fabry-Perot interferometer (EFPI) and fiber Bragg grating (FBG) sensors is presented that is based on a Michelson interferometer and combines the methods of lowcoherence interference and Fourier transform spectrum. Signals from EFPI and FBG sensors are obtained simultaneously by scanning one arm of a Michelson interferometer, and an algorithm model is established to process the signals and retrieve both the wavelength of the FBG and the cavity length of the EFPI at the same time, which are then used to determine the strain and temperature.
A novel fluorescent chemosensing hybrid material (Py-SBA-15) for detecting Hg 2+ ions in water wa... more A novel fluorescent chemosensing hybrid material (Py-SBA-15) for detecting Hg 2+ ions in water was prepared through the functionalization of mesoporous silica (SBA-15) with a modified fluorescent chromophore, 1-(4′-hydroxyphenyl)-4-pyrenyl-2,3-diaza-1,3-butadiene (Py-OH). Py-OH ...
Novel upconversion nanocomposites with nanoporous structure were presented in this paper. Silica-... more Novel upconversion nanocomposites with nanoporous structure were presented in this paper. Silica-coated cubic NaYF4:Yb3+, Tm3+ nanoparticles were first prepared. After annealing, monodisperse cubic/hexagonal mixed phases NaYF4:Yb3+, Tm3+@SiO2 nanoparticles were obtained, and the NaYF4:Yb3+, Tm3+ cores became nanoporous. To the best of our knowledge, the nanoporous structure in NaYF4:Yb3+, Tm3+@SiO2 nanocomposites was observed for the first time. They demonstrate increased upconversion emission compared with unannealed dense NaYF4:Yb3+, Tm3+ nanoparticles due to the appearance of the hexagonal NaYF4:Yb3+, Tm3+. The silica shell not only makes the nanocomposites possess bio-affinity but also protects the NaYF4:Yb3+, Tm3+ cores from aggregating and growing up. Thus the upconversion, nanoporous and bio-affinity properties were combined into one single nanoparticle. The nanocomposites have been characterized by X-ray diffraction (XRD), field-emission scanning electron microscopy (FE-SEM)...
Extrinsic Fabry-Perot interferometer (EFPI) and fiber Bragg grating (FBG) sensors can construct o... more Extrinsic Fabry-Perot interferometer (EFPI) and fiber Bragg grating (FBG) sensors can construct one of most promising sensor group for simultaneous temperature and strain measurement in structure health monitoring. The demodulation of the sensor group is critical. Here, a parallel demodulation system used for the goal is presented, which is based on a Michelson interferometer and combines the method of low
Purpose: To investigate the efficiency of lysozyme and albumin removal from silicone hydrogel and... more Purpose: To investigate the efficiency of lysozyme and albumin removal from silicone hydrogel and conventional contact lenses, using a polyhexamethylene biguanide multipurpose solution (MPS) in a soaking or rubbing/soaking application and a hydrogen peroxide system (H2O2). Methods: Etafilcon A, lotrafilcon B and balafilcon A materials were incubated in protein solutions for up to 14 days. Lenses were either placed in
The spleen combines the innate and adaptive immune systems in a uniquely organized way. The excis... more The spleen combines the innate and adaptive immune systems in a uniquely organized way. The excision of spleen will induce many complications, especially the increased susceptibility to infections. Recent research shows that besides playing roles during the immune responses, the spleen is also an important organ during immunoregulation, which is different from other secondary lymphoid organs. This unique function is mainly realized by modulating cell migration and proliferation in the spleen. This review provides a better understanding of the functions of this complex organ gained from recent studies.
Proceedings of 2011 International Conference on Electronics and Optoelectronics, 2011
A new method was proposed to measure the surface deformation, where the optics is irradiated by a... more A new method was proposed to measure the surface deformation, where the optics is irradiated by a high power laser when they are measured with ZYGO interferometer. The fiber with output shaper was used to transmit the laser. With this simple and convenient method, measuring k9, fused silica and antireflection coated silica windows, where a power of 200W doubled YAG
ABSTRACT Core–shell structured YVO4:Eu3+@SiO2 nanocomposite particles were synthesized using a on... more ABSTRACT Core–shell structured YVO4:Eu3+@SiO2 nanocomposite particles were synthesized using a one-pot reverse microemulsion method and characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM), UV absorption spectra, and photoluminescent spectra. The nanocomposite particles are well-dispersed and about 20 nm in average size. The synthesis method is of one-pot, simplifying the preparation of this kind of core–shell structured nanocomposites. The formation process of these nanocomposite particles is suggested and the photoluminescence properties of them are studied and compared with those of uncoated YVO4:Eu3+ sample.
a b s t r a c t A novel method using particle-packing technique to fabricate capillary electropho... more a b s t r a c t A novel method using particle-packing technique to fabricate capillary electrophoresis (CE)-based immobilized enzyme reactor (IMER) was accomplished by utilizing perfusive silica single particles as the frits and large-pore beads as the enzyme supports. The fabrication procedure is rapid and simple; the length and enzyme loading amount of the CE-IMERs could be easily adjusted. Performance and feasibility of the CE-IMERs were investigated using on-line trypsin digestion as the model enzyme reaction. High reproducible on-line enzyme assay was demonstrated with RSD less than 4.1% and 3.8% for peak area and migration time of the substrate and product over 100 consecutive runs, respectively. The enzyme can still maintain the activity for at least 10 days, indicating remarkably stability of the CE-IMERs. The CE-IMERs were successfully applied for accurate analysis of trypsin inhibition as well as on-line digestion of standard proteins (myoglobin and BSA). The present method provides a new interesting alternative to open-tubular and monolithic CE-IMERs, thus expands the application of the CE technique for on-line enzyme assay and analysis and characterization of peptides and proteins.
The complete cDNA and deduced amino-acid sequences of ribosomal proteins L34 (AmphiL34) and S29 (... more The complete cDNA and deduced amino-acid sequences of ribosomal proteins L34 (AmphiL34) and S29 (AmphiS29) from the amphioxus Branchiostoma belcheri tsingtauense were identified in this study. The AmphiL34 cDNA is 435 nucleotides in length and encodes a 118 amino-acid protein with calculated molecular mass of 13.6 kDa. It shares 53.6-67.5% amino-acid sequence identity with its eukaryotic counterparts including human, mouse, rat, pig, frog, catfish, fruit fly, mosquito, armyworm, nematode and yeast. The AmphiS29 cDNA comprises 453 nucleotides and codes for a 56 amino-acid protein with a calculated molecular mass of 6.6 kDa. It shows 66.1-78.6% amino-acid sequence identity to eukaryotic S29 proteins from human, mouse, rat, pig, zebrafish, seahorse, fruit fly, nematode, sea hare and yeast. AmphiL34 contains a putative nucleolar localization signal, while AmphiS29 has a zinc finger-like domain. A phylogenetic tree deduced from the conserved sequences of AmphiL34 and AmphiS29 and other k...
AIM: To investigate the relationship between H pylori in- fection and PTEN, cyclinE expression in... more AIM: To investigate the relationship between H pylori in- fection and PTEN, cyclinE expression in gastric cancer and adjacent mucosal tissues, and to study the possible mecha- nism of H pylori in gastric carcinogenesis. METHODS: Both rapid urease and pathological test were used to examine H pylori in 59 cases of specimen. The expression of PTEN and cyclinE in gastric
We report here theoretical and experimental studies on the sequential diffusion injection (SDI) f... more We report here theoretical and experimental studies on the sequential diffusion injection (SDI) for CE analysis. Based on the Fick's second law, a theoretical model for two-dimensional (2-D) diffusion has been developed for our SDI system. The 2-D diffusion model has been demonstrated via systematic experimental studies using standard nicotinamide adenine dinucleotide (NADH) as the model analyte. The results show that the dependence of the NADH peak area (corresponding to the injection amount) on the initial sample concentration, the injection time or the capillary-gap distance is consistent with the deduction of the 2-D diffusion model. It is indicated that the 2-D diffusion, both in longitudinal and transverse directions of the capillary, enhances the injection efficiency in comparison to classical concentration diffusion on the plane interface, and improves the accuracy of the sequential injection without any physical disturbance of the capillary inlet. With the insight under...
Through the functionalization of multiwalled carbon nanotubes (MWCNTs) by 0,0(-diallylbisphenol A... more Through the functionalization of multiwalled carbon nanotubes (MWCNTs) by 0,0(-diallylbisphenol A (DBA), the interface situation between MWCNTs and bismaleimide (BMI) was improved, as detected by scanning electron microscope (SEM) and dynamic mechanical analysis (DMA). The improved interface situation was considered to be the main reason for the huge increased microhardness value and greatly improved the microtribological property of MWCNTs/BMI composites. Besides, the wear mechanism for the composite was also believed to be related to the interfacial situation. The rough wavelike worn surface of pure BMI resin is attributed to its poor load capacity. The smoother waterfall-shape worn surface of MWCNTs/BMI is related to the interface formed by the addition of MWCNTs while the ultrasmooth worn surface of DBA modified MWCNTs/BMI is due to the greatly improved interfacial interaction of the composite.
Abstract The reaction of naphthalene with the OH radical was studied in a 10 m3 smog chamber. Rea... more Abstract The reaction of naphthalene with the OH radical was studied in a 10 m3 smog chamber. Reaction products identified include 1, 2-benzenedicarboxaldehyde, phthalic anhydride, phthalic acid, 1 (3H)-isobenzofuranone, 1, 4-naphthalenedione, 4-methyl-2H-1 ...
Background: Centromere protein A (CENP-A) plays important roles in cell-cycle regulation and gene... more Background: Centromere protein A (CENP-A) plays important roles in cell-cycle regulation and genetic stability. Herein, we aimed to investigate its expression pattern, clinical significance, and biological function in hepatocellular carcinoma (HCC).
Introduction -We report a rapid and accurate method to determine the natural occurrence of aflato... more Introduction -We report a rapid and accurate method to determine the natural occurrence of aflatoxins (AFs) B1, B2, G1 and G2 in medicinal herbs and the analysis of 174 commercial samples by this method. Objective -The aim of the present work is to examine the occurrence of the aflatoxins B1, B2, G1 and G2 in common medicinal herbs. Methodology -The AFs were extracted, purified by immunoaffinity column and analysed by high-performance liquid chromatography-tandem quadrupole mass spectrometry with electrospray ionisation (HPLC-MS/MS). Results -The AFs can be separated within 6 min using an Agilent XDB C 18 -column. The target analyte AFB1 could be detected at 0.14 mg/kg. A good linear relationship was found for AFG1 and AFB1 in 1-100 pg and AFG2 and AFB2 in 0.8-30 pg (r > 0.9995). The analyte recovery under three different spiking levels was 64-100% with the relative standard deviations (RSD) below 8.19%. Conclusion -This simple and accurate method effectively eliminates false positive detection and can be used to determine the AFs in medicinal herbs to control product quality. We found that in the 174 samples tested, 27 were contaminated with AFs. The incidences of AFB1, AFB2, AFG1 and AFG2 in the samples tested were 15.52%, 14.37%, 6.32% and 2.30%, respectively. We proposed 10 mg/kg total AFs and 5 mg/kg AFB1 as the reasonable maximum limits (ML) in medicinal herbs, and there are 10 samples (5.71% occurrence) in our test that exceeded this proposed limit. a High level: 10 ngÁmL -1 AFB1, 10 ngÁmL -1 AFG1, 3.0 ngÁmL -1 AFB2, 3.0 ngÁmL -1 AFG2. b Medium level: 2 ngÁmL -1 AFB1, 2 ngÁmL -1 AFG1, 0.6 ngÁmL -1 AFB2, 0.6 ngÁmL -1 AFG2. c Low level: 0.5 ngÁmL -1 AFB1, 0.5 ngÁmL -1 AFG1, 0.15 ngÁmL -1 AFB2, 0.15 ngÁmL -1 AFG2. Figure 3. MRM mass spectrum of tomentose pummelo peel: 1, reference substances comprising a mixture of aflatoxins; 2, tomentose pummelo peel.
Physica E: Low-dimensional Systems and Nanostructures, 2013
ABSTRACT By using nonequilibrium Green's function method, we study the phonon transport p... more ABSTRACT By using nonequilibrium Green's function method, we study the phonon transport properties in S-shaped graphene nano-junctions (GNJs). Interesting transmission phenomenon is found. The transmission spectrum of low frequency phonon shows forbidden frequency band, by changing the width W2 of the S-shaped GNJs. These low frequency forbidden bands are sensitive to their periodic geometric shape of GNJs. These thermal transport phenomena can be explained by analyzing the phonon transmission coefficient. This paper illustrates the thermal transport mechanisms in the different S-shaped GNJs, and the results could provide significant physical models and theoretical validity in designing the thermal devices based on the GNJs.
The aim of this study was to explore the usefulness of multiple excitation autofluorescence (AF) ... more The aim of this study was to explore the usefulness of multiple excitation autofluorescence (AF) and a spectral feature-based pattern recognition in classification of colon tissues. Under four different excitation wavelengths (337, 375, 405 and 460 nm), AF spectra of freshly excised normal and adenocarcinoma colon tissues were measured. Pattern recognition method including features extraction, data reduction using principal component analysis (PCA) and Fisher's discriminant analysis (FDA) were performed for classification. There was a significantly difference between spectral patterns of normal and adenocarcinoma tissues. Compared with the other three excitation wavelengths, the AF spectra obtained under 337 nm excitation provided more diagnostic information, but also more sensitive to the trivial change resulted from neoplastic transformation. For discriminating normal from adenocarcinoma tissues, the sensitivity, specificity and accuracy using 337 nm excitation in the present study were 88.9%, 80.0% and 83.9%, respectively. Compared these values with those determined from multispectral data analysis, our findings indicate that the latter has higher specificity while maintaining the same sensitivity (sensitivity 88.9% vs. 88.9%, specificity 91.4% vs. 80.0%, and accuracy 90.3% vs. 83.9%). This study suggests that the pattern recognition of the multiple excitation AF spectra is an effective algorithm for improving the diagnostic accuracy of adenocarcinoma.
The aim of this study was to compare the sensitivity of hematoporphyrin monomethyl ether (HMME)-m... more The aim of this study was to compare the sensitivity of hematoporphyrin monomethyl ether (HMME)-mediated PDT in the Epstein-Barr virus (EBV) positive and negative human nasopharyngeal carcinoma (NPC) cells. The intracellular uptake of HMME in C666-1 (EBV+) and CNE2 (EBV-) cells was quantitatively determined after incubating with different concentration of HMME. The subcellular localization of HMME was examined under a laser scanning fluorescence microscopy. The survival rate of C666-1 and CNE2 cells after HMME PDT was evaluated with clonogenic assay. The EBV- CNE2 cells showed higher intracellular uptake of HMME and lower survival rate than EBV+ C666-1 cells. There was no significant difference in terms of subcellular localization of HMME between C666-1 and CNE2 cells. The sensitivity of EBV- CNE2 cells to HMME-mediated PDT was significantly higher than that of EBV+ C666-1 cells. The intracellular uptake of HMME plays a key role in determining the PDT sensitivity.
A parallel demodulation system for extrinsic Fabry-Perot interferometer (EFPI) and fiber Bragg gr... more A parallel demodulation system for extrinsic Fabry-Perot interferometer (EFPI) and fiber Bragg grating (FBG) sensors is presented that is based on a Michelson interferometer and combines the methods of lowcoherence interference and Fourier transform spectrum. Signals from EFPI and FBG sensors are obtained simultaneously by scanning one arm of a Michelson interferometer, and an algorithm model is established to process the signals and retrieve both the wavelength of the FBG and the cavity length of the EFPI at the same time, which are then used to determine the strain and temperature.
A novel fluorescent chemosensing hybrid material (Py-SBA-15) for detecting Hg 2+ ions in water wa... more A novel fluorescent chemosensing hybrid material (Py-SBA-15) for detecting Hg 2+ ions in water was prepared through the functionalization of mesoporous silica (SBA-15) with a modified fluorescent chromophore, 1-(4′-hydroxyphenyl)-4-pyrenyl-2,3-diaza-1,3-butadiene (Py-OH). Py-OH ...
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