Papers by mohamed Khoulali
Uncommon spinal involvement of ALK-positive anaplastic large cell lymphoma: A pediatric case report and literature review
Radiology Case Reports
Pediatric sellar-suprasellar tuberculosis: A case report and review of the literature
Surgical Neurology International
Background: Pediatric sellar-suprasellar tuberculosis is a rare form of tuberculosis that affects... more Background: Pediatric sellar-suprasellar tuberculosis is a rare form of tuberculosis that affects the pituitary gland and surrounding areas in the brain. It can be difficult to diagnose based on clinical and radiological signs alone, as they can be similar to other pituitary masses. A combination of biological, hormonal, and imaging examinations can aid in making an accurate diagnosis. It is important to consider tuberculosis in the differential diagnosis of sellar-suprasellar masses in the pediatric population, especially in areas with a high prevalence of tuberculosis. Case Description: A 17-year-old male with no history of illness showed up with a series of symptoms, including headaches and vision problems. A sellar-suprasellar lesion was seen on imaging, along with several minor lesions. The diagnosis of tuberculosis meningitis with cerebral and pituitary tuberculoma was made after cerebrospinal fluid analysis revealed the presence of tuberculosis. Treatment with anti-tuberculos...
Atypical radiological aspect of meningioma: Web-like enhancement
Radiology Case Reports
Bobble head doll syndrome (BHDS): Case report
Radiology Case Reports
Pan African Medical Journal, 2018
Les mélanocytomes méningés sont des tumeurs pigmentées rares qui affectent le système nerveux cen... more Les mélanocytomes méningés sont des tumeurs pigmentées rares qui affectent le système nerveux central et se développent dans les leptoméninges cérébrospinales. Nous présentons deux cas de mélanocytomes méningés montrant une très grande diversité évolutive: une très longue évolution locale d'une lésion méningée cérébrale, avec transformation maligne ayant entrainé le décès après 32 ans pour le premier malade, et la localisation intra-médullaire ectopique à diffusion méningée massive très rapide, pour la deuxième malade. Ces deux cas montrent le profil évolutif incertain des mélanocytomes méningés et ces lésions peuvent devenir agressives dont le pronostic est sombre malgré des thérapeutiques intensives.
Neurochirurgie, Jun 1, 2018
Société de neurochirurgie de langue franç aise-Communications affichées présentées à la Réunion a... more Société de neurochirurgie de langue franç aise-Communications affichées présentées à la Réunion annuelle de Paris / Neurochirurgie 64 (2018) 240-277 d'un nodule de 1,6 centimètre prenant fortement le contraste. Une laminectomie dorsale de trois étages a permis de retrouver une lésion jaunâtre, élastique, intramédullaire, entourée par une capsule, adhérente à la moelle. L'exérèse chirurgicale a été incomplète. L'examen histopathologique a mis en évidence un schwannome. L'évolution postopératoire a été marquée par une aggravation du déficit neurologique. Discussion-conclusion Le SIM pur, sans localisation extramédullaire, ainsi que le SIM sans association avec une neurofibromatose est exceptionnel. La présence des cellules de Schwann à l'intérieur de la moelle. S'explique, selon la plupart des auteurs, par un trouble de l'embryogenèse. Il n'a pas de symptomatologie spécifique. Le diagnostic positif est largement facilité par l'IRM. La qualité de l'exérèse chirurgicale et le statut neurologique préopératoire déterminent le pronostic fonctionnel. Déclaration de liens d'intérêts Les auteurs déclarent ne pas avoir de liens d'intérêts.
Journal of Health and Medical Sciences
Metastatic disease to the calvaria with invasive dural venous sinus extension presents unique dia... more Metastatic disease to the calvaria with invasive dural venous sinus extension presents unique diagnostic and management challenges in cancer patients. Treatment options are not standardized. We report a case of a 62-year-old female who presented with breast cancer calvarial metastasis and upper sagittal sinus extension, and in whom a complete resection of the lesion was performed. Surgery may be helpful in selected cancer patients for symptomatic relief as well as survival benefits.
Spinal mesenchymal chondrosarcoma: A case report of a rare malignant tumor
Surgical Neurology International
Background: Mesenchymal chondrosarcoma is an uncommon malignant variant of chondrosarcoma that ma... more Background: Mesenchymal chondrosarcoma is an uncommon malignant variant of chondrosarcoma that mainly affects the bones and cartilaginous tissues, but may rarely involve the spine. Careful preoperative planning for surgical tumor removal and spine reconstruction is mandatory and must be based on oncologic and surgical staging. Case Description: Over 1 month, a 16-year-old female became paraplegic with a T9 sensory level and urinary dysfunction. The magnetic resonance imaging revealed an intraspinal extradural T7-T9 mass that was isointense in T1W1 and markedly enhanced with gadolinium. The patient underwent gross-total tumor resection followed by an osteoplastic laminectomy with fusion. The histological examination was consistent with a mesenchymal chondrosarcoma. She had received radiation and chemotherapy. One year later, she was readmitted for tumor recurrence with multiple metastases involving L1, the lung, and peritoneum. Despite full course of radiotherapy and chemotherapy, sh...
The white cerebellum sign with good prognosis: A case report
Radiology Case Reports
Endoscopic Infratentorial Supracerebellar approach for the mesencephalic enlarged Virchow Robin Space fenestration, an alternative minimally invasive route
Interdisciplinary Neurosurgery
The white cerebellum sign with good prognosis: A case report
Radiology Case Reports
Surgical Neurology International
Background: Vestibular schwannomas (VSs) are one of the most common tumors of the cerebellopontin... more Background: Vestibular schwannomas (VSs) are one of the most common tumors of the cerebellopontine angle and internal meatus, the evolution of this type of tumors is defined as unpredictable, it can enlarge or present a spontaneous regression as described in rare cases. Case Description: We report the case of a 50-year-old woman who presented with a large right full cystic VS revealed by a balance disorder associated with deafness in the right ear which spontaneously regressed. The patient was lost to follow-up for 3 years, the symptomatology improved, and the tumor clearly regressed without any surgical treatment. Conclusion: Spontaneous regression of solid-cystic VS is possible but rare, it can be part of conservative treatment, which requires regular follow-up.
Giant Arachnoid Cyst Associated with an Orbital Meningocele: A Case Report and Cystoperitoneal Shunt Management
Pediatric Neurosurgery, 2021
Introduction: Intracranial arachnoid cysts (ACs) are space-occupying lesions that typically remai... more Introduction: Intracranial arachnoid cysts (ACs) are space-occupying lesions that typically remain stable in size and clinically silent over time. Case Report: We describe an unusual pediatric case of enlarged AC impressive by its compressive phenomena. An 11-month-old girl presented with remarkable macrocephaly associated with a cystic orbital tumor. CT scan and MRI studies revealed a large intracranial ACs extending in the orbit with an orbital meningocele (OM). The intracranial cyst did communicate with the orbital one into a bony defect in the right inner region of the orbital roof and represses the globe outward. A cystoperitoneal shunting procedure was performed to remove the mass effect as soon as possible and facilitate normal development. Discussion/Conclusion: Cysts in infants younger than 1 year of age are remarkably different from those in older children and adults in terms of cyst localization and enlargement. Classically described complications result from compression ...
Spinal Cord Series and Cases, 2020
Introduction Neurosyphilis is a sexually transmitted disease secondary to the invasion of the cen... more Introduction Neurosyphilis is a sexually transmitted disease secondary to the invasion of the central nervous system by the Treponema pallidum. The spinal syphilitic gumma is rare. Case presentation We report a case of extradural cervical spinal syphilitic gumma revealed by spinal cord compression in a 58-year-old male. The epidural lesion was removed via a posterior approach. Histological examination revealed syphilis. Syphilis serologies were positive. Brain MRI showed an associated cerebro-meningeal syphilitic gumma. Antibiotic regime based on aqueous penicillin G was introduced for 14 days. Discussion Currently, there is an increase in the frequency of syphilis and changes in its clinical manifestations. Neurosyphilis can take atypical forms. Spinal syphilitic gumma is a rare manifestation and its association with cerebral involvement is exceptional. Diagnosis is based on serologies in the blood and cerebrospinal fluid. The place of imagery, especially magnetic resonance imaging, is essential. Neurosyphilis should be discussed as a possible differential diagnosis in evaluation of spinal and cerebral lesions.
Pan African Medical Journal, 2018
Tumeurs du cône médullaire et de la queue de cheval associées à l'hydrocéphalie chronique: à prop... more Tumeurs du cône médullaire et de la queue de cheval associées à l'hydrocéphalie chronique: à propos de 2 cas Tumors of the conus medullaris and of the cauda equina associated with chronic hydrocephalus: about 2 cases
Pan African Medical Journal, 2019
Traitement chirurgical des kystes de Tarlov sacrés: à propos de 20 cas Surgical treatment of sacr... more Traitement chirurgical des kystes de Tarlov sacrés: à propos de 20 cas Surgical treatment of sacral Tarlov cysts: about 20 cases
Journal of Health and Medical Sciences
Metastatic disease to the calvaria with invasive dural venous sinus extension presents unique dia... more Metastatic disease to the calvaria with invasive dural venous sinus extension presents unique diagnostic and management challenges in cancer patients. Treatment options are not standardized. We report a case of a 62-year-old female who presented with breast cancer calvarial metastasis and upper sagittal sinus extension, and in whom a complete resection of the lesion was performed. Surgery may be helpful in selected cancer patients for symptomatic relief as well as survival benefits.
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Papers by mohamed Khoulali