Papers by Ishaan Kapoor
Networks have become an increasingly central theme within the field of neuroscience as research t... more Networks have become an increasingly central theme within the field of neuroscience as research takes a more global approach as opposed to a localised one (Fair et al., 2009; Menon, 2015). Converging data in systems neuroscience suggest a high functional connectivity (FC) between the salience network and other neural networks (Seeley et al., 2007; Manoliu et al., 2013). There is often an overlap of nodes between networks, an anatomical link that appendages to their functional correlation (Heuvel and Sporns, 2013; Menon, 2015), and in absence of an anatomical overlap, correlation is derived from functional inter-network edges such as the afferent link between the ventromedial prefrontal cortex (vmPFC) and dorsolateral prefrontal cortex (dlPFC) in triggering affective response.
In this paper I aim to extend the established connection between the default mode network and the salience network of the brain and present that anti correlation along which they interact in the neural processes of emotional feeling and decision making. As per the James-Lange theory, visceral afferents are necessary in creating a unique and discrete emotional moment in the brain which then leads to an actionable emotional response. Thus, predicated on this theory, emotion becomes the neural foundation of decision making. The salience network and the default mode network are known to activate simultaneously during moral reasoning tasks and as schizophrenia results in aberrant insular functioning, there is a simultaneous impairment in the default mode network functioning and switching of salience.
Through Damasio’s somatic marker hypothesis (SMH) and top-down (Seth 2013, 2014) and bottom up models (AD Craig, 2004) of cognition I attempt to model the anti correlation between activity of the two networks and their inversely related functions of prediction and arousal. Through this I wish to prove the role of the SN and DMN in the related neural processes of affect and decision making.
The hidden cranial lobe is arguably one of the lesser studied areas of the brain. Only recently h... more The hidden cranial lobe is arguably one of the lesser studied areas of the brain. Only recently has the insular cortex (IC) found itself a significant amount of interest in the scientific community which has stimulated extensive research in the field. The Isle of Riel is located directly beneath the overlap of the temporal, frontal and parietal cortices and has long been known for its central role as a afferent of the dorsal anterior cingulate cortex (dACC) in the salience network (SN). Recently, converging evidence in anatomical and systems neuroscience expands the spectrum of functions that the IC regulates or is involved in.
Findings on the functional connectivity (FC) of the IC with other neural hubs including the amygdala, ACC, prefrontal cortices (PFCs) and hypothalamus imply its functional involvement in several neural processed including those of homeostatic regulation, activating somatic markers (Craig, 2005) and production of emotional moments. In this paper I attempt to draw a link and uncover certain aspects of the anatomical and functional connectivity of the insula.
The insula has long been credited with housing the integral understanding of ones self and has been dubbed as the epicentre of interoception. through assessing its role in top-down and bottom-up cognition, I attempt to theoretically infer the role of the insula through its preferential activation along with several other neural nodes and edges laying a particular emphasis on the edges that appendage off the cranial nerves and its preferential activation in neural processes such as emotional and speech processing. Over the course of this paper I hope to broaden this link and draw a neural network that would link sensory perception and the process of interoception to a section of the insula and progression of impulses across the granular gradient in the insula to assess its role as a neural sensory hub.
Conference Presentations by Ishaan Kapoor
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Papers by Ishaan Kapoor
In this paper I aim to extend the established connection between the default mode network and the salience network of the brain and present that anti correlation along which they interact in the neural processes of emotional feeling and decision making. As per the James-Lange theory, visceral afferents are necessary in creating a unique and discrete emotional moment in the brain which then leads to an actionable emotional response. Thus, predicated on this theory, emotion becomes the neural foundation of decision making. The salience network and the default mode network are known to activate simultaneously during moral reasoning tasks and as schizophrenia results in aberrant insular functioning, there is a simultaneous impairment in the default mode network functioning and switching of salience.
Through Damasio’s somatic marker hypothesis (SMH) and top-down (Seth 2013, 2014) and bottom up models (AD Craig, 2004) of cognition I attempt to model the anti correlation between activity of the two networks and their inversely related functions of prediction and arousal. Through this I wish to prove the role of the SN and DMN in the related neural processes of affect and decision making.
Findings on the functional connectivity (FC) of the IC with other neural hubs including the amygdala, ACC, prefrontal cortices (PFCs) and hypothalamus imply its functional involvement in several neural processed including those of homeostatic regulation, activating somatic markers (Craig, 2005) and production of emotional moments. In this paper I attempt to draw a link and uncover certain aspects of the anatomical and functional connectivity of the insula.
The insula has long been credited with housing the integral understanding of ones self and has been dubbed as the epicentre of interoception. through assessing its role in top-down and bottom-up cognition, I attempt to theoretically infer the role of the insula through its preferential activation along with several other neural nodes and edges laying a particular emphasis on the edges that appendage off the cranial nerves and its preferential activation in neural processes such as emotional and speech processing. Over the course of this paper I hope to broaden this link and draw a neural network that would link sensory perception and the process of interoception to a section of the insula and progression of impulses across the granular gradient in the insula to assess its role as a neural sensory hub.
Conference Presentations by Ishaan Kapoor
In this paper I aim to extend the established connection between the default mode network and the salience network of the brain and present that anti correlation along which they interact in the neural processes of emotional feeling and decision making. As per the James-Lange theory, visceral afferents are necessary in creating a unique and discrete emotional moment in the brain which then leads to an actionable emotional response. Thus, predicated on this theory, emotion becomes the neural foundation of decision making. The salience network and the default mode network are known to activate simultaneously during moral reasoning tasks and as schizophrenia results in aberrant insular functioning, there is a simultaneous impairment in the default mode network functioning and switching of salience.
Through Damasio’s somatic marker hypothesis (SMH) and top-down (Seth 2013, 2014) and bottom up models (AD Craig, 2004) of cognition I attempt to model the anti correlation between activity of the two networks and their inversely related functions of prediction and arousal. Through this I wish to prove the role of the SN and DMN in the related neural processes of affect and decision making.
Findings on the functional connectivity (FC) of the IC with other neural hubs including the amygdala, ACC, prefrontal cortices (PFCs) and hypothalamus imply its functional involvement in several neural processed including those of homeostatic regulation, activating somatic markers (Craig, 2005) and production of emotional moments. In this paper I attempt to draw a link and uncover certain aspects of the anatomical and functional connectivity of the insula.
The insula has long been credited with housing the integral understanding of ones self and has been dubbed as the epicentre of interoception. through assessing its role in top-down and bottom-up cognition, I attempt to theoretically infer the role of the insula through its preferential activation along with several other neural nodes and edges laying a particular emphasis on the edges that appendage off the cranial nerves and its preferential activation in neural processes such as emotional and speech processing. Over the course of this paper I hope to broaden this link and draw a neural network that would link sensory perception and the process of interoception to a section of the insula and progression of impulses across the granular gradient in the insula to assess its role as a neural sensory hub.