Papers by Jurema Corrêa da Mota
BMC Infectious Diseases
Background Agile, accessible and cheap diagnosis of hepatitis C virus (HCV) infection is essentia... more Background Agile, accessible and cheap diagnosis of hepatitis C virus (HCV) infection is essential to achieve the elimination of this infection, worldwide, as mandated by the World Health Organzation as part of its strategy for 2030. Dried blood spots (DBS) can be an attractive alternative for sample collection among people living in remote areas and vulnerable populations due to the less invasive collection, its biosafety, and storage & transportation of samples at room temperature. Design This study aims to estimate the usefulness of dried blood spot samples for the diagnosis and the assessment of HCV infection rates in three different settings in Brazil. Cross-sectional analysis of a sample collection from different populations, aiming to assess the performance of the testing algorithms and respective procedures among different populations with diverse background infection rates. Methods We reported the evaluation of DBS as alternative samples for detecting anti-HCV in different ...
World Journal of Hepatology
BACKGROUND To achieve the elimination of hepatitis B and C, there is an urgent need to develop al... more BACKGROUND To achieve the elimination of hepatitis B and C, there is an urgent need to develop alternative strategies to increase the access of diagnosis, particularly among key populations such as people living with human immunodeficiency virus (HIV), individuals with coagulopathies and chronic kidney disease (CKD) patients. AIM To evaluate the use of dried blood spot (DBS) in the detection of hepatitis B virus (HBV) and hepatitis C virus (HCV) markers. METHODS A total of 430 individuals comprised of people living with HIV, coagulopathies and CKD provided paired serum and DBS samples. HBsAg, anti-HBc and anti-HCV were tested in those samples using a commercial electrochemiluminescence. Demographic and selected behavioral variables were evaluated to assess possible association with HBV and HCV positivity. RESULTS Using DBS, HBsAg prevalence varied from 3.9% to 22.1%, anti-HBc rates varied from 25.5% to 45.6% and anti-HCV positivity ranged from 15.9% to 41.2% in key populations. Specificities of HBV and HCV tests using DBS varied from 88.9% to 100%. The HBsAg assay demonstrated the best performance in CKD and coagulopathy individuals and the anti-HCV test had a sensitivity and specificity of 100% in people living with HIV. Accuracy of HBV and HCV detection in DBS varied from 90.2% to 100%. In the CKD group, HBsAg positivity was associated with infrequent use of condoms, and anti-HBc positivity was associated with sharing nail cutters/razors/toothbrushes. Anti-HCV reactivity was positively associated with a history of transplantation and length of time using hemodialysis in both specimens. In people living with HIV, only the male gender was associated with anti-HBc positivity in serum and DBS. CONCLUSION DBS with electrochemiluminescence are useful tools for the diagnosis and prevalence studies of hepatitis B and C among key populations and may increase the opportunity to foster prevention and treatment.
Brazilian Journal of Psychiatry
Objectives: Previous studies have estimated the 30-day prevalence of alcohol use to be approximat... more Objectives: Previous studies have estimated the 30-day prevalence of alcohol use to be approximately 21% among youth in Brazil, despite the legal drinking age of 18 years. The present study aimed to determine the prevalence of underage drinking and its associated factors among adolescents in Brazil. Methods: The 3rd National Survey on Drug Use by the Brazilian Population (III Levantamento Nacional sobre o Uso de Drogas pela Populac¸ã o Brasileira) is a nationwide, multi-stage, probabilitysample household survey. Herein, youth between the ages of 12-17 years were included. Lifetime and 12-month alcohol use prevalence were estimated. Factors associated with 12-month alcohol use were evaluated through multivariate analysis considering survey weights and design. Results: Overall, 628 youth were interviewed. Estimated lifetime and 12-month alcohol use were 34.3% (standard error [SE] = 1.9) and 22.2% (SE = 1.7), respectively. Factors associated with 12-month drinking were: other/no religion vs. Christianity; living in rural vs. urban areas; self-reported diagnosis of depression vs. no self-reported depression; lifetime tobacco use vs. no history of tobacco use; and any illicit drug use vs. no history of illicit drug use. Conclusion: Considering that alcohol use is a major risk factor for early death among Brazilian youth, our findings highlight the importance of preventative measures to reduce underage drinking.
Características de usuários de crack quanto à situação de moradia no Nordeste brasileiro, 2011-20... more Características de usuários de crack quanto à situação de moradia no Nordeste brasileiro, 2011-2013 Housing characteristics of crack cocaine users in Northeast Brazil, 2011-2013 Resumo Objetivou-se comparar características sociodemográficas, padrões de consumo de substâncias, comportamento sexual, utilização de serviços de saúde e envolvimento criminal de usuários, domiciliados e em situação de rua. Dados secundários do Inquérito Nacional sobre Uso do Crack, utilizando análise discriminante e de correspondência para comparar características dos usuários segundo condição de moradia. O modelo final de regressão logística evidenciou associações entre "situação de rua" e ser do sexo feminino, trabalho descontínuo, consumo de tabaco e "oxi" nos últimos 30 dias, uso de serviços de alimentação gratuita, baixo acesso a tratamento e frequentes detenções no último ano. Na análise de correspondência observou-se proximidade no espaço analítico de "troca de sexo por drogas", "trabalho informal", "idade" >31 anos, "baixo acesso a CAPS-ad", "problemas com a justiça criminal" e "sexo feminino" com os usuários de crack desabrigados. Pouco se sabe sobre usuários de crack em contexto na região Nordeste do Brasil. Os resultados evidenciam dois subgrupos com características específicas. Enquanto os domiciliados têm acesso aos serviços de CAPS-ad e outras clínicas especializadas, os usuários em situação de rua relataram, basicamente, acesso a serviços de alimentação gratuita e redução de danos. Palavras-chave Vulnerabilidade social, Cocaína crack, Pessoas em situação de rua
Substance Abuse, 2021
Background: Responses to problem substance use have largely focused on illicit drugs, but reports... more Background: Responses to problem substance use have largely focused on illicit drugs, but reports on rising prescription drug misuse worldwide raise questions about their combined use with alcohol and potential consequences. The current study assessed prevalence of alcohol in conjunction with nonmedical opioid and benzodiazepine use across a nationally representative sample of adults in Brazil. Methods: Cross-sectional data on prevalence were estimated from the 2015 Brazilian Household Survey on Substance Use. We estimated past month nonmedical use of benzodiazepines and alcohol and past month nonmedical use of opioids and alcohol among adults who reported any past-year alcohol use. Zero-inflated Poisson models assessed independent correlates of alcohol and nonmedical opioid use, and alcohol and nonmedical benzodiazepine use. Results: Among adults who reported past year alcohol use, 0.4% (N = 257,051) reported past month alcohol and non-medical benzodiazepine use, and 0.5% (N = 337,333) reported past month alcohol and non-medical opioid use. Factors independently associated with co-use of alcohol and benzodiazepines included having depression (adjusted prevalence ratio (aPR):4.61 (95%CI 1.76-12.08)), anxiety (aPR:4.21 (95%CI 1.59-11.16)) and tobacco use (aPR: 5.48 (95%CI 2.26-13.27)). Factors associated with past-month alcohol and opioid use included having experienced physical or a threat of violence (aPR: 4.59 (95%CI 1.89-11.14)), and tobacco use (aPR:2.81(95%CI:1.29-6.12)). Conclusions: Co-use of prescription drugs with alcohol remains relatively rare among Brazilians, but findings point to a unique profile of persons at risk. Results of this study are important in light of changing dynamics and international markets of prescription drugs and the need for more research on use of these substances on a global scale.
AIDS Care, 2020
We compared the prevalence of of non-injecting drug use (NIDU) and Self-Rated Health (SRH) among ... more We compared the prevalence of of non-injecting drug use (NIDU) and Self-Rated Health (SRH) among individuals self-reporting as HIV-positive (PLWHA), HIV-negative and unknown at the III Brazilian Household Survey on Substance Use. Overall, 16,273 individuals, 12-65 years old, were interviewed in 2015. Prevalence and Standard Error (SE) were estimated considering the complex sample design and weight calibration. Chi-square tests with Rao-Scott adjustment were used to test independence between NIDU, SRH and HIV status. PLWHA presented higher frequencies of 12-month use for most substances than those reporting to be HIV-negative: alcohol use prevalence was 49.5% (SE 12.8) vs. 43.1% (SE 0.7), p = 0.34; tobacco 45.3% (SE 12.7) vs. 15.3% (SE 0.4), p < 0.01; amphetamines 1.7% (SE 1.7) vs. 0.3% (SE 0.1), p = 0.51; cannabis 10.5%(SE 6.7) vs. 2.5%(0.2), p = 0.06; powder cocaine 3.6% (SE 3.0) vs. 0.9% (SE 0.1), p = 0.45; crack-cocaine 5.3% (SE 3.2) vs. 0.3% (SE 0.1), p < 0.01; inhalants 3.6% (SE 3.0) vs. 0.2% (SE 0), p = 0.03; ketamine 1.7% (SE 1.7) vs. 0.1% (SE 0), p = 0.23; and opioids 1.7% (SE 1.7) vs. 1.4% (SE 0.2), p = 0.93. PLWHA also reported worse SRH. Our results and the scarcity of integrated substance use and HIV treatments call for innovative, cost-effective approaches to tackle these public health challenges.
Global Public Health, 2019
Prior studies on substance use in Brazil have not focused on opioid misuse, previously thought to... more Prior studies on substance use in Brazil have not focused on opioid misuse, previously thought to be nearly non-existent. This paper presents new findings on heroin and non-medical use of opioid analgesics. Data come from the 2015 Brazilian Household Survey on Substance Use (BHSU-3), a nationally representative survey estimating epidemiological parameters related to substance use by residents across Brazil. BHSU-3 used stratified multi-stage probability sampling across multiple geographic domains of interest, resulting in 16,273 interviews with household residents. Lifetime heroin use among Brazilians was 0.3 (95% C.I:0.2-0.4). Lifetime, past-year, and past-month nonmedical use of opioid analgesics were respectively 2.9 (95%C.
Journal of Affective Disorders, 2021
Background: This study aimed to compare self-reported changes on lifestyle behaviors during two p... more Background: This study aimed to compare self-reported changes on lifestyle behaviors during two phases of the COVID-19 pandemic in Spain, and to evaluate clinical and sociodemographic factors associated with lifestyles. Methods: Two cross-sectional web surveys were conducted during lockdown (April 15-May 15, 2020) and seven months later (November 16-December 16, 2020). Lifestyle behaviors were self-reported by a multidimensional scale (SMILE-C). Two separate samples of respondents were analyzed. A multivariate regression model was performed to evaluate the association of SMILE-C scores with demographic and clinical variables. Results: The sample comprised, 3412 participants from the first survey (S1) and in the S1 and 3635 from the second (S2). SMILE-C score decreased across surveys (p < 0.001). The rates of positive screenings for depression and anxiety were similar between the surveys, whereas those for alcohol abuse decreased (p < 0.001). Most participants in S2 reported that their lifestyle had not changed compared to those before the pandemic. Variables independently associated with an unhealthier lifestyle were working as an essential worker, lower educational level, previous mental disease, worse self-rated health, totally/moderate changes on diet, sleep or social support, as well as positive screenings for alcohol abuse, anxiety and depression. Limitations: The cross-sectional design and recruitment by non-probabilistic methods limit inferring causality and the external validity of the results.
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Scientific Reports, 2022
We conducted a systematic review and meta-analysis of studies assessing HCV infection rates in ha... more We conducted a systematic review and meta-analysis of studies assessing HCV infection rates in haemodialysis patients in Brazil (Prospero CRD #42021275068). We included studies on patients under haemodialysis, comprising both convenience samples and exhaustive information from selected services. Patients underwent HCV serological testing with or without confirmation by HCV RNA PCR. Exclusion criteria were the following: absence of primary empirical information and studies without information on their respective settings, study year, accurate infection rates, or full specification of diagnostic tests. Studies with samples ≤ 30 and serial assessments with repeated information were also excluded. Reference databases included PubMed, LILACS, Scopus, and Web of Science for the period 1989–2019. A systematic review was carried out, followed by two independent meta-analyses: (i) studies with data on HCV prevalence and (ii) studies with a confirmatory PCR (i.e., active infection), respectiv...
Global Public Health, 2020
This study explores associated factors and perceptions of oral health among crack users recruited... more This study explores associated factors and perceptions of oral health among crack users recruited in open drug scenes in Brazil. A mixed methods approach was used. The quantitative component analysed findings from a large (N = 7381), population-based survey. The outcomes under analysis were ‘self-perception of oral health’ and ‘self-reporting of problems affecting the mouth, teeth and gingiva (gums)’. The qualitative component comprised a focus group, with 12 individuals recruited from a drug treatment clinic. Lower self-perception of oral health problems vis-à-vis a higher prevalence of problems affecting the mouth, teeth, and gingiva were found in users who had a lower level of education, used substances daily, had worse self-perception of physical health, did not receive health care and regularly used alcohol and/or tobacco. The results show an association between substance use and decline in oral health, as well as the lack of health services focusing on such issues. Oral health...
Background The syndemics theory seeks to understand the effect of multiple synergic problems in p... more Background The syndemics theory seeks to understand the effect of multiple synergic problems in promoting poor health outcomes. To disentangle which and how syndemic conditions affect quality of life (QoL) may be important to improve well-being of people living with HIV/AIDS (PLWHA). This study evaluates the association between syndemic conditions and quality of life among people living with HIV/AIDS. METHODS This was a secondary analysis from data obtained between 2014 and 2017 among PLWHA under care in Rio de Janeiro, Brazil. The outcomes were the six QoL domains (physical, psychological, level of independence, social relationships, environmental, and spirituality) measured through the World Health Organization Quality of Life in HIV infection scale, abbreviated version (WHOQOL-HIV-BREF). The independent variables were demographic and clinical characteristics, syndemic conditions (binge drinking, compulsive sexual behavior, polysubstance use, intimate partner violence, and depress...
Revista de Psiquiatría y Salud Mental (English Edition), 2021
Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on ... more Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre-including this research content-immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
Journal of Virological Methods, 2020
Dried blood spots (DBS) testing might increase the access for Hepatitis B virus (HBV) diagnosis, ... more Dried blood spots (DBS) testing might increase the access for Hepatitis B virus (HBV) diagnosis, but little is known about the performance of these assays in real life conditions. This study aims to evaluate the diagnostic accuracy of HBsAg, anti-HBc and anti-HBs detection in DBS in clinical settings and field studies and to evaluate demographic and risk behaviour according the presence of HBsAg and anti-HBc. Paired sera and DBS samples were obtained from 2,309 individuals from 3 groups, defined as follows: G1: clinical setting (n = 509), G2: general population (n = 1,305) and G3: vulnerable individuals that could be more exposed to blood contact (n = 485). Sera and DBS were tested using commercial enzyme immunoassay (EIA), with some modifications added. Using DBS samples, the specificity values were above 90% for HBsAg and anti-HBc in all groups and for anti-HBs range from 58.6% to 85%. HBsAg testing had the best performance in GI (sensitivity = 84.4%) and among those samples that the paired serum also presented anti-HBc marker (sensitivity = 91.6%). High sensitivity of anti-HBc testing in DBS samples was observed in GI (80.8%) and among HBV active cases (HBsAg+/anti-HBc+) (98.4%). Testing of anti-HBs in DBS showed the highest sensitivity in GIII (65.5%), in previous HBV exposed and cured individuals and when serum titers were above 100 IU/mL (86.7%). DBS samples could be used for screening and prevalence studies for HBsAg and anti-HBc, particularly in clinical settings and among HBV active cases in field studies.
BMC Infectious Diseases, 2019
Background: Hepatitis B virus (HBV) testing in oral fluid samples may provide advantages in diagn... more Background: Hepatitis B virus (HBV) testing in oral fluid samples may provide advantages in diagnosis, screening or prevalence studies, especially among individuals with venous access difficulties. This study aims to optimize one commercially available assay for detecting total anti-HBc marker in oral fluid samples and to evaluate its utility under real life conditions in different settings for the purposes of prevalence and diagnostic studies. Methods: Oral fluid was collected using a Salivette device and some parameters were initially evaluated: type of elution buffer and sample volume. Thereafter, the utility of oral fluid samples for detection of anti-HBc was evaluated in real life conditions in which, 1296 individuals gave serum and oral fluid samples. All serum samples were submitted to commercial EIAs to detect total anti-HBc, according to the manufacturer's instructions and oral fluid samples according to previous optimization. Results: In optimization evaluation, PBS/BSA 0.5% and 100 μL of oral fluid (volume was two-fold increased compared to serum in EIA) were chosen as transport buffer and sample volume. In the field study, anti-HBc was detected in 211 out of 1296 serum samples giving overall oral fluid sensitivity of 52.6% and specificity of 96%. Concordance was higher in ambulatory setting (67.7) compared to general population (31.8). Mean ± standard deviation values of optical density/cutoff (OD/CO) in serum samples were higher in false-negative oral fluid samples than those seen in true positive samples. Sensitivity was higher in those presenting active infection compared to anti-HBc isolate and past infection. Sensitivity also increased in the ambulatory group when HCV individuals were excluded. Conclusions: It was possible to optimize a commercial EIA for detecting anti-HBc in oral fluid samples and where the highest concordance was found in ambulatory settings and among individuals with active infection.
PLOS ONE, 2019
The temporal and spatial evolution of malaria was described for the postfrontier phase of the Bra... more The temporal and spatial evolution of malaria was described for the postfrontier phase of the Brazilian Amazon in 2003-2013. The current ecological study aimed to understand the relationship between spatial population mobility and the distribution of malaria cases. The study identified epidemiologically relevant areas using regional statistical modeling and spatial analyses that considered differential infections and types of work activities. Annual parasite incidence (API) in the region was highest in hotspots along the Amazon River and in the south and west settlement zone of Hilé ia, with concentrations in environmental protection areas and açaí and Brazil nut extraction areas. The dispersal force decreased in the Central Amazon due to rapid urbanization and improved socioeconomic conditions for workers in consolidated settlement areas. The study characterized the spatial patterns of disease transmission according to the economic activity and regionalization of geographic areas, confirming that the incidence of infection by work activity and labor flow is linked to extractive activities and agricultural settlements.
Scientific Reports, 2019
Despite the initiative by WHO and other international organizations to eliminate HCV in the mediu... more Despite the initiative by WHO and other international organizations to eliminate HCV in the medium term, hepatitis C infection is still a major public health problem. Even non-injecting drugs users who engage in harmful or addictive drug use are at greater risk of acquiring the infection, when compared to the general population. This study evaluate risk factors for HCV infection in users of crack/cocaine in Brazil, using multilevel models that incorporate variations in the sensitivity and specificity of the respective diagnostic tests. The sample included all the participants of a national survey on street crack cocaine users with serologically reactive result in the rapid test for the HCV as well as 4 non-reactive controls, matched by sex, age category, and major geographic region of residence. Multilevel logistic regression models were used, with and without incorporation of the diagnostic test's sensitivity and specificity values. The odds of HCV infection were 85% higher among polydrug users, 7.81 times higher among injecting drug users, and 3.69 times higher in those reporting to have genital ulcers. Statistical modeling strategies that incorporate the sensitivity and specificity of diagnostic tests in challenging settings are useful for studying the association between risk factors and infection status. Despite undeniable strides in the treatment of hepatitis C infection and the strategy led by the WHO (World Health Organization) to eliminate hepatitis B and C by 2030 1,2 , these infections are still a major global public health problem, especially hepatitis C, for which no vaccine exists, and for which the existing treatments are expensive, although curative. Acute HCV infection is usually asymptomatic, and an estimated 15% to 45% infected persons eliminate the virus spontaneously without any treatment. The other cases (55% to 85% of persons) develop chronic HCV infection, and among these, there is a high (15% to 30%) estimated risk of hepatic cirrhosis in the absence of therapeutic intervention 1 . According to the World Health Organization 3 , approximately 700 thousand people die per year in the world from complications of HCV infection. Due to the largely asymptomatic nature of HCV infection, many HCV-positive individuals are actually unaware of their serological status. Others have been diagnosed but are unable to obtain treatment. The lack of a quick and reliable diagnosis and the high cost and limited access to new treatments are barriers to the control and elimination of the disease . Parenteral infection is still the main form of HCV transmission, and an estimated 1.75 million new HCV infections occurred in the world in the year 2015 alone 5 . Persons that use illegal drugs are often exposed to increased risk of various infectious diseases, basically due to their behaviors and drug consuming habits, in addition to the risks and harms associated with the respective self-administration routes . Various studies have reported high HCV prevalence rates, especially among people who inject drugs (PWID) . As for non-injecting drug users (NIDU), who smoke, inhale, snort, or sniff substances like heroin, [powder] cocaine, and crack cocaine, for example, there are reports of higher HCV prevalence rates than in the general population, suggesting that there may be some other relevant form of transmission, despite persistent controversies on viral viability in
World Journal of Hepatology, 2018
AIM To evaluate viral hepatitis knowledge among individuals from different resource areas and hea... more AIM To evaluate viral hepatitis knowledge among individuals from different resource areas and health conditions to identify possible gaps. METHODS A cross-sectional, descriptive study was carried out among 447 individuals from five distinct populations in Brazil: Southeast Viral Hepatitis Ambulatory (n = 100), South (n = 89) and Northeast (n = 114) Health Center, Southeast (n = 77) and Northeast (n = 67) low resource areas. All individuals answered a questionnaire assessing sociodemographic characteristics and viral hepatitis awareness. The perception was scored based on the average number of correct answers of all participants and categorized as "low" (0-28 correct answers) or "desirable" (29-46 correct answers). Associations between sociodemographic characteristics and perception were also evaluated. RESULTS A low level of knowledge was observed in individuals from Northeast Health Center, Northeast and Southeast low resource areas while desirable knowledge was observed in individuals from Viral Hepatitis Ambulatory and South Health Center. According to sociodemographic characteristics, desirable scores were more common among those with secondary education (47.1%), those who declared themselves as white (46.3%), and those who lived in houses with three individuals (25.5%). Multivariate analysis showed an association between viral hepatitis perception and type of population. CONCLUSION The results demonstrated high level of knowledge among study participants from health clinics from the Southeast region of Brazil and the importance of education programs in increasing the level of knowledge in low resource areas.
Cadernos de saude publica, Aug 20, 2018
Despite substantial improvement in prognosis and quality of life among people living with HIV/AID... more Despite substantial improvement in prognosis and quality of life among people living with HIV/AIDS (PLWHA) in Brazil, inequalities in access to treatment remain. We assessed the impact of these inequalities on survival in Rio de Janeiro over a 12-year period (2000/11). Data were merged from four databases that comprise the national AIDS monitoring system: SINAN-AIDS (Brazilian Information System for Notificable Diseases; AIDS cases), SISCEL (laboratory tests), SICLOM (electronic dispensing system), and SIM (Brazilian Mortality Information System), using probabilistic linkage. Cox regressions were fitted to assess the impact of HAART (highly active antiretroviral therapy) on AIDS-related mortality among men who have sex with men (MSM), people who inject drugs (PWID), and heterosexuals diagnosed with AIDS, between 2000 and 2011, in the city of Rio de Janeiro, RJ, Brazil. Among 15,420 cases, 60.7% were heterosexuals, 36.1% MSM and 3.2% PWID. There were 2,807 (18.2%) deaths and the medi...
Epidemiologia e Serviços de Saúde, 2016
Objetivo: descrever a proporção de registros repetidos no Sistema de Informação de Agravos de Not... more Objetivo: descrever a proporção de registros repetidos no Sistema de Informação de Agravos de Notificação do Brasil, em 2008 e 2009. Métodos: para identificação de registros repetidos de casos de dengue, hanseníase, leishmaniose visceral (LV) e leishmaniose tegumentar americana (LTA), meningites e tuberculose, utilizou-se o aplicativo Reclink III®; calculouse a proporção dos registros repetidos segundo macrorregiões, Unidades da Federação e categorias de porte populacional do município. Resultados: LV e meningites apresentaram maiores proporções de registros repetidos (5,3% e 3,6%, respectivamente) e hanseníase a menor (0,7%); proporções mais elevadas foram observadas no Rio Grande do Norte (6,8% para LV; 5,1% para hanseníase), Rio de Janeiro (2,5% para tuberculose; 4,9% para meningites) e Goiás (2,0% para dengue; 7,2% para meningites). Conclusão: a macrorregião Nordeste concentrou maior proporção de registros repetidos para quatro das seis doenças estudadas; à exceção da dengue, o percentual de repetição foi menor nos municipios mais populosos.
Cadernos de Saúde Pública, 2015
Resumo O objetivo foi comparar as estimativas das causas externas provenientes do estudo Carga Gl... more Resumo O objetivo foi comparar as estimativas das causas externas provenientes do estudo Carga Global de Doenças, entre os anos 1998 e 2008. A estimação do DALY (disability-adjusted life year) e do YLL (years of life lost) foi baseada em metodologia do estudo Carga Global de Doenças. Para o cálculo do YLD (years lived with disability), foram incluídas informações sobre atendimentos em emergências. Para comparabilidade, fez-se necessária a aplicação da mesma metodologia nos dois momentos analisados, tendo sido a mais recente eleita como padrão de referência. Em ambos os anos as causas externas foram responsáveis por cerca de 10% do total do DALY. Entretanto, sua distribuição interna apresentou marcada diferença entre as regiões do Brasil, com queda no Sudeste e aumento no Norte e Nordeste. Houve aumento das causas intencionais e o DALY se tornou mais letal (maior parcela de YLL). Espera-se que tais resultados balizem a formulação de políticas e/ou o aprimoramento das já existentes co...
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Papers by Jurema Corrêa da Mota