Introduction: Periodic paralysis is a group of rare neuromuscular disorders presenting with episo... more Introduction: Periodic paralysis is a group of rare neuromuscular disorders presenting with episodes of painless paralysis often incited by stress such as exercise. Differentiating hypokalemic periodic paralysis (HPP) from secondary hypokalemia can present a challenge. case report: A 26-year-old Hispanic male with no significant past medical history presented with periodic muscular weakness, areflexia, and paralysis. the patient’s potassium level on admission was 1.6 mEq/l with no other electrolyte abnormalities or electrocardiogram changes. there was a complete resolution of symptoms with IV and oral potassium. the diagnosis of acquired non-thyrotoxic HPP was given based on the patient’s history, his presenting symptoms, ruling out secondary causes of hypokalemia, and resolution with correction of potassium levels. conclusion: Hypokalemic periodic paralysis most commonly affects Asians, and is tightly associated with thyrotoxicosis. treatment of HPP relies on rapid identification and understanding of underlying cause. In an acute disabling attack, as seen in this patient, oral potassium and 24 hour cardiac monitoring for rebound hyperkalemia are recommended. We report an uncommon case Keerthana K. Kumar1, Zuhal Kadhim1, Jagan K. Mohan3 Affiliations: 1Saint James School of Medicine, Bonaire, Netherlands; 2Emory University School of Medicine, Atlanta, GA; 3Department of Neurology, Holy Cross Hospital, Chicago, IL. Corresponding Author: Keerthana K. Kumar, Saint James School of Medicine, C/o Human Resource Development Services (HRDS) Inc, 1480 Renaissance Drive, Suite 300, Park Ridge, IL 60068; Email : [email protected] Received: 25 September 2015 Accepted: 19 November 2015 Published: 29 February 2016 of acquired non-thyrotoxic HPP, as indicated by the patient’s history, presentation, initial laboratory values, and resolution after potassium correction.
Sand is commonly produced besides petroleum fluids and it presents a major erosional hazard leadi... more Sand is commonly produced besides petroleum fluids and it presents a major erosional hazard leading to pipe failures. Particle erosion is a complex process in which material is removed due to the repeated particle impacts. Conventionally, a CFD flow solver and computationally intensive lagrangian particle tracking sub-routines, known as Eulerian-Lagrangian (E-L) model, along with empirical erosion equations are used to predict the erosion rates. The present work introduces an Eulerian-Eulerian (E-E) approach in which the multiphase granular model resolves the solid phase and obviates the need of particles tracking. Particle-laden turbulent flow across a flow restrictor, based on an experimental study, is chosen for validation. Numerical experiments are done in Simcenter STAR-CCM+. Comparison with the experimental data demonstrate a good agreement and in particular, the E-E model yields reliable predictions of impact wear locations, erosion rates as those of E-L model. A 90° square bend is also simulated and comparison of erosion rates on the concave wall demonstrate that E-E model can be used as an alternate to computationally expensive approaches.
Key Words Succinyl choline chloride, Bromothymol blue, Colorimetry, Validation. A simple and new ... more Key Words Succinyl choline chloride, Bromothymol blue, Colorimetry, Validation. A simple and new colorimetric method was developed for the estimation of succinyl choline chloride. The proposed colorimetric method is based on the reaction between succinyl choline chloride and bromothymol blue reagent, followed by colour complex formation. Parameters affecting the reaction were studied and conditions were optimized. The absorption maximum for the colour complex was observed at 450 nm. Linearity was obtained in the concentration range of 70-600 µg/ml for succinyl choline chloride colour complex. The developed method was optimised and validated. The method was successfully applied for the estimation of succinyl choline chloride in bulk and in injection.
Many studies have reported greater drug uptake into brain than that predicted based upon existing... more Many studies have reported greater drug uptake into brain than that predicted based upon existing models using the free fraction (f u) of drug in arterial serum. To explain this difference, circulating plasma proteins have been suggested to interact with capillary membrane in vivo to produce a conformational change that favors net drug dissociation and elevation of f u. Albumin, the principal binding protein in plasma, has two main drug binding sites, Sudlow I and II. We tested this hypothesis using drugs that bind selectively to either site I (warfarin) or site II (ibuprofen) as well as mixed ligands that have affinity for both sites (tolbutamide, valproate). Brain uptake was determined in the presence and absence of albumin using the in situ rat brain perfusion technique. Unidirectional brain uptake transfer constants (K in) were measured and compared to those predicted using the modified Kety-Crone-Renkin model: K in = F (1-e-fu x PSu/F), where F is perfusion flow and PS u is the permeability-surface area product to free drug of brain capillaries. The results demonstrated good agreement between measured and predicted K in over a 100-fold range in perfusion fluid albumin concentration using albumin from three different species (i.e., human, bovine and rat) as well as whole rat serum. K in decreased in the presence of albumin in direct proportion to perfusion fluid f u with constant PS u. The results show that brain uptake of selected Sudlow site I and II ligands matches that predicted by the modified Kety-Crone-Renkin model with no evidence for enhanced dissociation.
This paper presents a new electrically small rectangular probe-fed micro-strip patch antenna load... more This paper presents a new electrically small rectangular probe-fed micro-strip patch antenna loaded with material Rogers rt/duriod5880(tm). The present dissertation deals with Electrically small antenna which are electrically small compared to wave length.the performance of electrically small antenna are closely related to their electrical size, so the gain can be increased to maintain radiating efficiency. The micro-strip patch antennas have been widely used in satellite and telecommunications for their good characteristics such as light weight, in expensive, low cost and so on. Here in this design slots are placed to form folded dipole, which increases the band width of the antenna. Different parameters like returnloss,gain (2d&3d), radiation pattern in θ, Ø directions, current distribution, E&H fields and vswr are simulated in HFSS 13.0.This type of proposed patch can be used for various applications in C & X-Bands.
A flexible and versatile solution to voltage qualit y problems is offered by active power filters... more A flexible and versatile solution to voltage qualit y problems is offered by active power filters. Curr ently they are based on PWM converters and used to connect to low and medium voltage distribution system in shunt or in series. Active power filters can perfor m one or more of the functions required to compensa te power systems in improving power quality. Hybrid Filter, which is a combination ofan active series fil ter and passive shunt filter is quite popular because t he solid-state devices used in the active series pa rt can be of reduced size and cost (about 5% of the load size ) and the major part of the hybrid filter is made o f the passive shunt L-C filter used to eliminate lower order harmonics. It has the capability of reducing voltage and current harmonics at a reasonable cost. To prov ide high power quality at the Point of Common Coupling (PCC) of power distribution systems, elimi nation of the harmonics is indispensably necessary. The power quality and allowable Harmo...
International Journal of Pharma Research and Health Sciences, 2020
Antioxidants are involved in the defense mechanism of the organism against the pathologies associ... more Antioxidants are involved in the defense mechanism of the organism against the pathologies associated to the attack of free radicals. Endogenous antioxidants are enzymes, like superoxide dismutase, catalase, glutathione peroxidase or nonenzymatic compounds, such as uric acid, bilirubin, albumin, metallothioneins. When endogenous factors cannot ensure a rigurous control and a complete protection of the organism against the reactive oxygen species, the need for exogenous antioxidants arises, as nutritional supplements or pharmaceutical products, which contain as active principle
IEEE Transactions on Wireless Communications, 2009
In cognitive radio (CR), a cognitive user must cease transmission or reduce the transmit power at... more In cognitive radio (CR), a cognitive user must cease transmission or reduce the transmit power at the band where a primary system (PS) is detected. To this end, a popular method for orthogonal frequency division multiplexing (OFDM) based CR is the active interference cancellation (AIC) which tunes the modulation of some subcarriers to minimize the interference to PS. This paper
Abstract Cognitive-ultra wideband (CUWB) offer remarkable enhancements from both system in terms... more Abstract Cognitive-ultra wideband (CUWB) offer remarkable enhancements from both system in terms of spectrum utilization and high data rates transmission. As the SNR per dimension in UWB systems is typically very low, MB-OFDM UWB in MIMO technology with channel ...
International Journal of Informatics and Communication Technology (IJ-ICT), 2012
One of the major difficulties in face recognition system is an in-depth pose verification problem... more One of the major difficulties in face recognition system is an in-depth pose verification problem. Face recognition is a broad area of research over the last 25 years. However, the field is highly unsolved, largely due to variations in pose, illumination and expression. In this paper, a Ternary Angle Oriented Face Recognition algorithm is proposed. In this algorithm, the data is made into two clusters namely, Clock wise and Anti-clock wise rotations. The image is extracted using angle oriented DCT (Discrete Cosine Transform) that invokes certain normalization techniques. Face Matching is compared to the technique of k-means. Based on Image Recognition pattern, the reliability of clusters is studied. The experimental results are verified.
The Direct3D10/SM4. 0 system [Blythe 2006] is the 4th generation programmable graphics processing... more The Direct3D10/SM4. 0 system [Blythe 2006] is the 4th generation programmable graphics processing units (GPUs) architecture. The new pipeline introduces significant additions and changes to prior generation pipeline. We explore these new features and experiment to judge their performance. The main facilities introduced that we ponder upon are, Unified Architecture providing common features set for all programmable stages, Geometry Shader which is a new programmable stage capable of generating additional ...
The ongoing pandemic of the new severe acute respiratory syndrome coronavirus (SARS-CoV-2) has ca... more The ongoing pandemic of the new severe acute respiratory syndrome coronavirus (SARS-CoV-2) has caused more than one million deaths, overwhelmed many public health systems, and led to a worldwide economic recession. This has raised an unprecedented need to develop antiviral drugs and vaccines, which requires profound knowledge of the fundamental pathology of the virus, including its entry, replication, and release from host cells. The genome of coronaviruses comprises around 30 kb of positive single-stranded RNA, representing one of the largest RNA genomes of viruses. The 5′ part of the genome encodes a large polyprotein, PP1ab, which gives rise to 16 non-structural proteins (nsp1-nsp16). Two proteases encoded in nsp3 and nsp5 cleave the polyprotein into individual proteins. Most nsps belong to the viral replicase complex that promotes replication of the viral genome and translation of structural proteins by producing subgenomic mRNAs. The replicase complexes are found on doublemembrane vesicles (DMVs) that contain viral double-stranded RNA. Expression of a small subset of viral proteins, including nsp3 and nsp4, is sufficient to induce formation of these DMVs in human cells, suggesting that both proteins deform host membranes into such structures. We will discuss the formation of DMVs and provide an overview of other membrane remodeling processes that are induced by coronaviruses.
A typical mammalian cell plasma membrane displays a high level of plasticity counter balanced wit... more A typical mammalian cell plasma membrane displays a high level of plasticity counter balanced with stability. The plasma membrane show various kinds of invaginations to meet physiological demands o ...
International journal of probiotics & prebiotics, 2018
In the present study, we have investigated the bioavailability of biotransformed organic zinc enr... more In the present study, we have investigated the bioavailability of biotransformed organic zinc enriched dahi in vivo. The results evidence that the rats fed with zinc enriched dahi (ZED and ZEP) significantly increased (p<0.001) body weight and food intake from zero to third weeks. Analysis of zinc by AAS in body parts of different rat groups indicated that zinc content was significantly higher (p<0.001) in serum, femur bone, liver and hair of rats fed ZED/ZEP. Basal diet and inorganic zinc sulphate fed rat group excreted a greater amount of zinc in faeces. The results of in-vivo studies indicated that the bioavailability of organic zinc through dahi/probiotic dahi is high compared to its inorganic form.
are Chief General Manager and Deputy General Manager, respectively of the Financial Stability Uni... more are Chief General Manager and Deputy General Manager, respectively of the Financial Stability Unit (FSU), Reserve Bank of India, Central Office, Mumbai. The views expressed in this paper are, however, their own. Authors thank Dr. Balwant Singh consultant FSU, RBI for useful guidance and Mr. Sanjay Singh Research officer FSU, RBI for technical assistance. We also thank the two referees who provided useful inputs.
Stress in liquidity is at the heart of any banking crisis in history. During the financial crisis... more Stress in liquidity is at the heart of any banking crisis in history. During the financial crisis of 2007-09, funding liquidity risk caused the collapse of interbank markets, which became the focus of authorities' attention at restoring order. Accordingly, central banks and other regulatory bodies worldwide have been evolving prudential liquidity norms in order to impart stability to financial systems. Apart from implementing newer norms on liquidity, they have been devising ways of assessing objectively liquidity conditions in the markets. As an end to this objective, various central banks have started identifying the indicators of liquidity and preparing a composite index thereof in order to have a bird's eye view of liquidity conditions across financial markets. In this study, a systemic liquidity index (SLI) is constructed considering prevailing rate variables across different financial markets in India. The SLI, so developed, is appropriately validated for its function as a metric for measuring systemic liquidity and its implications on the banks' performance.
Abstract: Face Recognition is a well-known image processing technique that has been used in many ... more Abstract: Face Recognition is a well-known image processing technique that has been used in many applications like Law enforcement security, Bio-Metric Systems etc. In this paper complete image of face recognition algorithm is proposed. In the prepared algorithm the local information is extracted using angle oriented discrete cosine transforms and invokes certain normalization techniques. To increase the Reliability of the Face detection process, neighborhood pixel information is incorporated into the proposed method. Also this study analyzes and compares the obtained results from the proposed Angle oriented face recognition with threshold based face detector to show the level of robustness using texture features in the proposed face detector. It was verified that a face recognition based on textual features can lead to an efficient and more reliable face detection method compared with KLT (Karhunen Loeve Transform), a threshold face detector.
Autophagy is a fundamental cellular recycling pathway that captures cytoplasmic material by a pha... more Autophagy is a fundamental cellular recycling pathway that captures cytoplasmic material by a phagophore membrane and delivers it to lysosomes for degradation. Nonselective phagophores are generated at specialized ER-domains termed omegasomes. Mechanistically, this process is not well understood. Here, we reconstituted the formation of phagophores from purified components on supported lipid bilayers and by ectopic induction of nonselective autophagy at the plasma membrane. We found that enzymatic conjugation of LC3B to model membranes induces the formation of phagophore-like membrane cups. LC3B functions as membrane anchor, ensuring a sustained interaction of the E3-like ligase complex ATG12¬–ATG5-ATG16L1 with membranes by forming extended membrane coats. ATG16L1 is the major membrane remodeling factor that induces positive membrane curvature, promotes cup formation and stabilizes the rim of membrane cups. Redirecting WIPI2 to the plasma membrane by expressing WIPI2-CAAX induced the...
Introduction: Periodic paralysis is a group of rare neuromuscular disorders presenting with episo... more Introduction: Periodic paralysis is a group of rare neuromuscular disorders presenting with episodes of painless paralysis often incited by stress such as exercise. Differentiating hypokalemic periodic paralysis (HPP) from secondary hypokalemia can present a challenge. case report: A 26-year-old Hispanic male with no significant past medical history presented with periodic muscular weakness, areflexia, and paralysis. the patient’s potassium level on admission was 1.6 mEq/l with no other electrolyte abnormalities or electrocardiogram changes. there was a complete resolution of symptoms with IV and oral potassium. the diagnosis of acquired non-thyrotoxic HPP was given based on the patient’s history, his presenting symptoms, ruling out secondary causes of hypokalemia, and resolution with correction of potassium levels. conclusion: Hypokalemic periodic paralysis most commonly affects Asians, and is tightly associated with thyrotoxicosis. treatment of HPP relies on rapid identification and understanding of underlying cause. In an acute disabling attack, as seen in this patient, oral potassium and 24 hour cardiac monitoring for rebound hyperkalemia are recommended. We report an uncommon case Keerthana K. Kumar1, Zuhal Kadhim1, Jagan K. Mohan3 Affiliations: 1Saint James School of Medicine, Bonaire, Netherlands; 2Emory University School of Medicine, Atlanta, GA; 3Department of Neurology, Holy Cross Hospital, Chicago, IL. Corresponding Author: Keerthana K. Kumar, Saint James School of Medicine, C/o Human Resource Development Services (HRDS) Inc, 1480 Renaissance Drive, Suite 300, Park Ridge, IL 60068; Email : [email protected] Received: 25 September 2015 Accepted: 19 November 2015 Published: 29 February 2016 of acquired non-thyrotoxic HPP, as indicated by the patient’s history, presentation, initial laboratory values, and resolution after potassium correction.
Sand is commonly produced besides petroleum fluids and it presents a major erosional hazard leadi... more Sand is commonly produced besides petroleum fluids and it presents a major erosional hazard leading to pipe failures. Particle erosion is a complex process in which material is removed due to the repeated particle impacts. Conventionally, a CFD flow solver and computationally intensive lagrangian particle tracking sub-routines, known as Eulerian-Lagrangian (E-L) model, along with empirical erosion equations are used to predict the erosion rates. The present work introduces an Eulerian-Eulerian (E-E) approach in which the multiphase granular model resolves the solid phase and obviates the need of particles tracking. Particle-laden turbulent flow across a flow restrictor, based on an experimental study, is chosen for validation. Numerical experiments are done in Simcenter STAR-CCM+. Comparison with the experimental data demonstrate a good agreement and in particular, the E-E model yields reliable predictions of impact wear locations, erosion rates as those of E-L model. A 90° square bend is also simulated and comparison of erosion rates on the concave wall demonstrate that E-E model can be used as an alternate to computationally expensive approaches.
Key Words Succinyl choline chloride, Bromothymol blue, Colorimetry, Validation. A simple and new ... more Key Words Succinyl choline chloride, Bromothymol blue, Colorimetry, Validation. A simple and new colorimetric method was developed for the estimation of succinyl choline chloride. The proposed colorimetric method is based on the reaction between succinyl choline chloride and bromothymol blue reagent, followed by colour complex formation. Parameters affecting the reaction were studied and conditions were optimized. The absorption maximum for the colour complex was observed at 450 nm. Linearity was obtained in the concentration range of 70-600 µg/ml for succinyl choline chloride colour complex. The developed method was optimised and validated. The method was successfully applied for the estimation of succinyl choline chloride in bulk and in injection.
Many studies have reported greater drug uptake into brain than that predicted based upon existing... more Many studies have reported greater drug uptake into brain than that predicted based upon existing models using the free fraction (f u) of drug in arterial serum. To explain this difference, circulating plasma proteins have been suggested to interact with capillary membrane in vivo to produce a conformational change that favors net drug dissociation and elevation of f u. Albumin, the principal binding protein in plasma, has two main drug binding sites, Sudlow I and II. We tested this hypothesis using drugs that bind selectively to either site I (warfarin) or site II (ibuprofen) as well as mixed ligands that have affinity for both sites (tolbutamide, valproate). Brain uptake was determined in the presence and absence of albumin using the in situ rat brain perfusion technique. Unidirectional brain uptake transfer constants (K in) were measured and compared to those predicted using the modified Kety-Crone-Renkin model: K in = F (1-e-fu x PSu/F), where F is perfusion flow and PS u is the permeability-surface area product to free drug of brain capillaries. The results demonstrated good agreement between measured and predicted K in over a 100-fold range in perfusion fluid albumin concentration using albumin from three different species (i.e., human, bovine and rat) as well as whole rat serum. K in decreased in the presence of albumin in direct proportion to perfusion fluid f u with constant PS u. The results show that brain uptake of selected Sudlow site I and II ligands matches that predicted by the modified Kety-Crone-Renkin model with no evidence for enhanced dissociation.
This paper presents a new electrically small rectangular probe-fed micro-strip patch antenna load... more This paper presents a new electrically small rectangular probe-fed micro-strip patch antenna loaded with material Rogers rt/duriod5880(tm). The present dissertation deals with Electrically small antenna which are electrically small compared to wave length.the performance of electrically small antenna are closely related to their electrical size, so the gain can be increased to maintain radiating efficiency. The micro-strip patch antennas have been widely used in satellite and telecommunications for their good characteristics such as light weight, in expensive, low cost and so on. Here in this design slots are placed to form folded dipole, which increases the band width of the antenna. Different parameters like returnloss,gain (2d&3d), radiation pattern in θ, Ø directions, current distribution, E&H fields and vswr are simulated in HFSS 13.0.This type of proposed patch can be used for various applications in C & X-Bands.
A flexible and versatile solution to voltage qualit y problems is offered by active power filters... more A flexible and versatile solution to voltage qualit y problems is offered by active power filters. Curr ently they are based on PWM converters and used to connect to low and medium voltage distribution system in shunt or in series. Active power filters can perfor m one or more of the functions required to compensa te power systems in improving power quality. Hybrid Filter, which is a combination ofan active series fil ter and passive shunt filter is quite popular because t he solid-state devices used in the active series pa rt can be of reduced size and cost (about 5% of the load size ) and the major part of the hybrid filter is made o f the passive shunt L-C filter used to eliminate lower order harmonics. It has the capability of reducing voltage and current harmonics at a reasonable cost. To prov ide high power quality at the Point of Common Coupling (PCC) of power distribution systems, elimi nation of the harmonics is indispensably necessary. The power quality and allowable Harmo...
International Journal of Pharma Research and Health Sciences, 2020
Antioxidants are involved in the defense mechanism of the organism against the pathologies associ... more Antioxidants are involved in the defense mechanism of the organism against the pathologies associated to the attack of free radicals. Endogenous antioxidants are enzymes, like superoxide dismutase, catalase, glutathione peroxidase or nonenzymatic compounds, such as uric acid, bilirubin, albumin, metallothioneins. When endogenous factors cannot ensure a rigurous control and a complete protection of the organism against the reactive oxygen species, the need for exogenous antioxidants arises, as nutritional supplements or pharmaceutical products, which contain as active principle
IEEE Transactions on Wireless Communications, 2009
In cognitive radio (CR), a cognitive user must cease transmission or reduce the transmit power at... more In cognitive radio (CR), a cognitive user must cease transmission or reduce the transmit power at the band where a primary system (PS) is detected. To this end, a popular method for orthogonal frequency division multiplexing (OFDM) based CR is the active interference cancellation (AIC) which tunes the modulation of some subcarriers to minimize the interference to PS. This paper
Abstract Cognitive-ultra wideband (CUWB) offer remarkable enhancements from both system in terms... more Abstract Cognitive-ultra wideband (CUWB) offer remarkable enhancements from both system in terms of spectrum utilization and high data rates transmission. As the SNR per dimension in UWB systems is typically very low, MB-OFDM UWB in MIMO technology with channel ...
International Journal of Informatics and Communication Technology (IJ-ICT), 2012
One of the major difficulties in face recognition system is an in-depth pose verification problem... more One of the major difficulties in face recognition system is an in-depth pose verification problem. Face recognition is a broad area of research over the last 25 years. However, the field is highly unsolved, largely due to variations in pose, illumination and expression. In this paper, a Ternary Angle Oriented Face Recognition algorithm is proposed. In this algorithm, the data is made into two clusters namely, Clock wise and Anti-clock wise rotations. The image is extracted using angle oriented DCT (Discrete Cosine Transform) that invokes certain normalization techniques. Face Matching is compared to the technique of k-means. Based on Image Recognition pattern, the reliability of clusters is studied. The experimental results are verified.
The Direct3D10/SM4. 0 system [Blythe 2006] is the 4th generation programmable graphics processing... more The Direct3D10/SM4. 0 system [Blythe 2006] is the 4th generation programmable graphics processing units (GPUs) architecture. The new pipeline introduces significant additions and changes to prior generation pipeline. We explore these new features and experiment to judge their performance. The main facilities introduced that we ponder upon are, Unified Architecture providing common features set for all programmable stages, Geometry Shader which is a new programmable stage capable of generating additional ...
The ongoing pandemic of the new severe acute respiratory syndrome coronavirus (SARS-CoV-2) has ca... more The ongoing pandemic of the new severe acute respiratory syndrome coronavirus (SARS-CoV-2) has caused more than one million deaths, overwhelmed many public health systems, and led to a worldwide economic recession. This has raised an unprecedented need to develop antiviral drugs and vaccines, which requires profound knowledge of the fundamental pathology of the virus, including its entry, replication, and release from host cells. The genome of coronaviruses comprises around 30 kb of positive single-stranded RNA, representing one of the largest RNA genomes of viruses. The 5′ part of the genome encodes a large polyprotein, PP1ab, which gives rise to 16 non-structural proteins (nsp1-nsp16). Two proteases encoded in nsp3 and nsp5 cleave the polyprotein into individual proteins. Most nsps belong to the viral replicase complex that promotes replication of the viral genome and translation of structural proteins by producing subgenomic mRNAs. The replicase complexes are found on doublemembrane vesicles (DMVs) that contain viral double-stranded RNA. Expression of a small subset of viral proteins, including nsp3 and nsp4, is sufficient to induce formation of these DMVs in human cells, suggesting that both proteins deform host membranes into such structures. We will discuss the formation of DMVs and provide an overview of other membrane remodeling processes that are induced by coronaviruses.
A typical mammalian cell plasma membrane displays a high level of plasticity counter balanced wit... more A typical mammalian cell plasma membrane displays a high level of plasticity counter balanced with stability. The plasma membrane show various kinds of invaginations to meet physiological demands o ...
International journal of probiotics & prebiotics, 2018
In the present study, we have investigated the bioavailability of biotransformed organic zinc enr... more In the present study, we have investigated the bioavailability of biotransformed organic zinc enriched dahi in vivo. The results evidence that the rats fed with zinc enriched dahi (ZED and ZEP) significantly increased (p<0.001) body weight and food intake from zero to third weeks. Analysis of zinc by AAS in body parts of different rat groups indicated that zinc content was significantly higher (p<0.001) in serum, femur bone, liver and hair of rats fed ZED/ZEP. Basal diet and inorganic zinc sulphate fed rat group excreted a greater amount of zinc in faeces. The results of in-vivo studies indicated that the bioavailability of organic zinc through dahi/probiotic dahi is high compared to its inorganic form.
are Chief General Manager and Deputy General Manager, respectively of the Financial Stability Uni... more are Chief General Manager and Deputy General Manager, respectively of the Financial Stability Unit (FSU), Reserve Bank of India, Central Office, Mumbai. The views expressed in this paper are, however, their own. Authors thank Dr. Balwant Singh consultant FSU, RBI for useful guidance and Mr. Sanjay Singh Research officer FSU, RBI for technical assistance. We also thank the two referees who provided useful inputs.
Stress in liquidity is at the heart of any banking crisis in history. During the financial crisis... more Stress in liquidity is at the heart of any banking crisis in history. During the financial crisis of 2007-09, funding liquidity risk caused the collapse of interbank markets, which became the focus of authorities' attention at restoring order. Accordingly, central banks and other regulatory bodies worldwide have been evolving prudential liquidity norms in order to impart stability to financial systems. Apart from implementing newer norms on liquidity, they have been devising ways of assessing objectively liquidity conditions in the markets. As an end to this objective, various central banks have started identifying the indicators of liquidity and preparing a composite index thereof in order to have a bird's eye view of liquidity conditions across financial markets. In this study, a systemic liquidity index (SLI) is constructed considering prevailing rate variables across different financial markets in India. The SLI, so developed, is appropriately validated for its function as a metric for measuring systemic liquidity and its implications on the banks' performance.
Abstract: Face Recognition is a well-known image processing technique that has been used in many ... more Abstract: Face Recognition is a well-known image processing technique that has been used in many applications like Law enforcement security, Bio-Metric Systems etc. In this paper complete image of face recognition algorithm is proposed. In the prepared algorithm the local information is extracted using angle oriented discrete cosine transforms and invokes certain normalization techniques. To increase the Reliability of the Face detection process, neighborhood pixel information is incorporated into the proposed method. Also this study analyzes and compares the obtained results from the proposed Angle oriented face recognition with threshold based face detector to show the level of robustness using texture features in the proposed face detector. It was verified that a face recognition based on textual features can lead to an efficient and more reliable face detection method compared with KLT (Karhunen Loeve Transform), a threshold face detector.
Autophagy is a fundamental cellular recycling pathway that captures cytoplasmic material by a pha... more Autophagy is a fundamental cellular recycling pathway that captures cytoplasmic material by a phagophore membrane and delivers it to lysosomes for degradation. Nonselective phagophores are generated at specialized ER-domains termed omegasomes. Mechanistically, this process is not well understood. Here, we reconstituted the formation of phagophores from purified components on supported lipid bilayers and by ectopic induction of nonselective autophagy at the plasma membrane. We found that enzymatic conjugation of LC3B to model membranes induces the formation of phagophore-like membrane cups. LC3B functions as membrane anchor, ensuring a sustained interaction of the E3-like ligase complex ATG12¬–ATG5-ATG16L1 with membranes by forming extended membrane coats. ATG16L1 is the major membrane remodeling factor that induces positive membrane curvature, promotes cup formation and stabilizes the rim of membrane cups. Redirecting WIPI2 to the plasma membrane by expressing WIPI2-CAAX induced the...
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Papers by Jagan Mohan