Papers by Ionara Barcelos
Reproductive BioMedicine Online, 2015
She has worked as Professor at the Faculty of Medicine of University of West Parana and at a priv... more She has worked as Professor at the Faculty of Medicine of University of West Parana and at a private reproductive medicine clinic. Her area of interest is reproductive medicine, endometriosis, assisted reproduction and recently epigenetics in reproduction.
Revista Brasileira de Ginecologia e Obstetrícia / RBGO Gynecology and Obstetrics
Objective The evaluation of the available evidence on vertical transmission by severe acute respi... more Objective The evaluation of the available evidence on vertical transmission by severe acute respiratory syndrome coronavirus 2 (SARS-CoV)-2. Data Sources An electronic search was performed on June 13, 2020 on the Embase, PubMed and Scopus databases using the following search terms: (Coronavirus OR COVID-19 OR COVID19 OR SARS-CoV-2 OR SARS-CoV2 OR SARSCoV2) AND (vertical OR pregnancy OR fetal). Selection of Studies The electronic search resulted in a total of 2,073 records. Titles and abstracts were reviewed by two authors (WPM, IDESB), who checked for duplicates using the pre-established criteria for screening (studies published in English without limitation regarding the date or the status of the publication). Data Collection Data extraction was performed in a standardized way, and the final eligibility was assessed by reading the full text of the articles. We retrieved data regarding the delivery of the potential cases of vertical transmission, as well as the main findings and con...
Reprodução & Climatério, 2013
Endometriosis - Basic Concepts and Current Research Trends, 2012
... there is evidence that oxidative stress might promote meiotic anomalies and pre-implantation ... more ... there is evidence that oxidative stress might promote meiotic anomalies and pre-implantation embryo development (Liu et al., 2003; Navarro et al ... of lutheal phase defects in women with endometriosis (Cheesman et al., 1983; Holtz et al., 1985; Saracoglu et al., 1985; Kaya & Oral ...
Revista Brasileira de Ginecologia e Obstetrícia, 2008
Revista Brasileira de Ginecologia e Obstetrícia, 2008
Revista Brasileira de Ginecologia e Obstetrícia, 2006
Journal of Medical Case Reports, 2009
Introduction: Endometrial ossification is an uncommon disease related to secondary infertility an... more Introduction: Endometrial ossification is an uncommon disease related to secondary infertility and its etiology and pathogenesis are controversial. More than 80% of reported cases occur after pregnancy.
Fertility and Sterility, 2007
Fertility and Sterility, 2007
Fertility and Sterility, 2007
criteria were included: Infertility > 1 year, < 39 years old, sperm account after swim-up >3 mill... more criteria were included: Infertility > 1 year, < 39 years old, sperm account after swim-up >3 millions/Ml. Exclusion criteria were: policystic ovary syndrome, severe endometriosis or uterine disease. Patients were randomized using a computer-generated randomization into 2 groups: Hp-Hmg group (n ¼ 32) receiving 75 IU/d, and r-FSH þ r-LH group (n ¼ 35), receiving 75 IU/d of r-FSH þ 75 IU/day of r-LH. Primary outcome was ovarian response in terms of oestradiol (E 2 ) increase (day 1 to day 6 of stimulation and Hcg day) and number of follicles recruited; Secondary outcomes were: duration of stimulation, total gonadotrophin dose, number of dominant follicles, clinical pregnancy rate (PR), ongoing PR, multiple pregnancy, miscarriage and cancellation rate due to risk of ovarian hyperstimulation syndrome (OHSS).
Fertility and Sterility, 2002
Objective: The in vitro maturation of immature oocytes retrieved from unstimulated ovaries has be... more Objective: The in vitro maturation of immature oocytes retrieved from unstimulated ovaries has been interested in assisted reproductive technology. Oocyte maturation, characterized by germinal vesicle (GV) breakdown, formation of first meiotic spindle, extrusion of the first polar body, and arrest in metaphase of the second meiotic division. However, numerous anomalies in the nuclear and cytoplasmic maturation were induced during in vitro maturation. This study was conducted to analyze spindle and chromosome configurations of in vitro maturation failure metaphase I (MI) arrested oocytes collected from PCO patients.
Fertility and Sterility, 2008
Fertility and Sterility, 2011
MATERIALS AND METHODS: Metaphase I oocytes were collected after 7 h of hCG and cultured for anoth... more MATERIALS AND METHODS: Metaphase I oocytes were collected after 7 h of hCG and cultured for another 2-4 hours. Within every 30 min checking time-frame, those which freshly extruded PBs were regarded as telophase I stage (some were confirmed with immunostaining) and then cryopreserved by the vitrification minimal volume method (Group A). The control oocytes were collected after 14 h of hCG and vitrified at metaphase II stage (Group B). After warming of oocytes from both groups, there was another 6 h (group A) and 2 h of culture (group B) before oocytes were subjected to activation (Ca 2+ -free CZB medium with 10 mM strontium chloride and 5 mg/ml Cytochalasin B for 6 h). To examine the total cell number, the blastocysts were fixed at 100 h post activation and stained with DAPI by epi-florescence microscopy. Results were analyzed by the Chi-square (P<0.05) statistical test.
Fertility and Sterility, 2011
RESULTS: A total of 5 men (ave 36.8 AE 10yrs) donated their specimens with a mean concentration o... more RESULTS: A total of 5 men (ave 36.8 AE 10yrs) donated their specimens with a mean concentration of 57.5 AE 43x10 6 /ml, motility of 43.0 AE 22%, and 6.4 AE 4% normal morphology. The presence of intact centrosomes in the infertile men was found in 79.0% (226/286) which was lower in comparison to the 92.0% identified in the controls (887/964, P¼0.0001). Interestingly, 2% (5/286) of the spermatozoa from the study group had only 1 signal. The structural integrity assay involving the centrosomal angle was measured consistently among infertile and controls between 30-35 . The assessment in human ciliated fibroblasts indicated that this angle is unique to the spermatozoon. After fixation and staining of 50 spermatozoa, only 38 head+tail pairs were identified. We identified intact centrosomes in 31.6% in isolated tails.
Fertility and Sterility, 2009
Expert Review of Obstetrics & Gynecology, 2008
Most endometriosis patients have fertility complaints and, in spite of the improvement of assiste... more Most endometriosis patients have fertility complaints and, in spite of the improvement of assisted reproduction procedures, outcomes remain unsatisfactory. This suggests that there are unknown ethiopathogenic influences that adversely affect fertility. Laparoscopic treatment of endometriosis is of questionable efficiency with regard to achieving better fertility results, with controversies mainly surrounding ovarian residual reserve. However, the laparoscopic approach follows good practice principles and is considered a minimally invasive procedure, with the advantage of being diagnostic and therapeutic. Decision to excise endometriomas must be taken cautiously, considering factors such as patient's age, previous ovarian reserve, previous pelvic surgery, presence of pain or malignancy suspicion, disease extension and the mean diameter of the lesions.
Reproductive BioMedicine Online, 2015
Aromatase plays a fundamental role in the establishment of oocyte quality, which might be comprom... more Aromatase plays a fundamental role in the establishment of oocyte quality, which might be compromised in infertile women with endometriosis. Thus, we compared the expression of the CYP19A1 gene (that encodes aromatase) in cumulus cells (CCs) and estradiol concentrations in the follicular fluid (FF) of infertile women with and without endometriosis submitted to ovarian stimulation for intracytoplasmic sperm injection.
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Papers by Ionara Barcelos