BACKGROUND The diagnostic accuracy of frozen section as an important source of information in sur... more BACKGROUND The diagnostic accuracy of frozen section as an important source of information in surgical pathology is important not only in the management of surgical patients but also as a measure of quality control in surgical pathology. In this study, we evaluated the diagnostic accuracy of frozen sections over a 6-year period in a teaching hospital in Iran. METHODS We retrospectively reviewed frozen sections performed in the Pathology Department of Taleghani Hospital (Shahid Beheshti University of Medical Sciences), Tehran, Iran from 2007 to 2013. The results were compared to the permanent sections to evaluate diagnostic accuracy, sensitivity and specificity, of frozen section test. Discordant cases were reassessed to find the reasons for discrepancy. RESULTS A total of 306 frozen section specimens from 176 surgical cases were evaluated. In eleven specimens (3.59%) the diagnoses were deferred. Of the remaining 295 specimens, 6 (2.03%) were discordant and 289 (97.96%) were concorda...
Backgrounds: Coronavirus disease 2019 (COVID-19) pandemic is considered as a global health challe... more Backgrounds: Coronavirus disease 2019 (COVID-19) pandemic is considered as a global health challenge, and Iran is among the top ten countries with the highest mortality rate. This study aimed to analyze epidemiological, clinical, and laboratory features of hospitalized SARS-CoV-2 infected patients and identify the risk factors of mortality among them to facilitate the prioritization of resources and vaccine allocation in the population using data available in a large university hospital in Tehran, Iran. Materials & Methods: From February 20 to May 14, 2020, a total of 684 COVID-19 confirmed cases were admitted to Imam Hossein University hospital in Tehran and enrolled in this retrospective observational study. Findings: The mean age of the participants was 59.48±16.65 years, and 55.8% were male. Compared to survivors, non-survivors (n=127, 18.57%) were older (69.09±14.16 vs. 57.29±16.40), had higher average number of comorbidities, and more frequently suffered from dyspnea, convulsion, loss of consciousness (LOC), tachycardia, tachypnea, and hypoxia. They also had higher levels of leukocytes, neutrophil count, C-reactive protein (CRP), creatine phosphokinase (CPK), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), international normalized ratio (INR), prothrombin time (PT), partial thromboplastin time (PTT), urea, and serum creatinine (p<.05). Serum potassium (K), lymphocyte count, hemoglobin, HCO 3 , and serum sodium (Na) were significantly lower in non-survivors. Multivariable logistic regression analysis results revealed that nine variables were positively associated with mortality. Conclusion: Among COVID-19 patients admitted to the hospital, having more than two or three comorbidities, loss of consciousness, SpO2 < 90%, increased CRP, CPK, urea, and serum potassium, were associated with mortality.
Journal of School of Public Health and Institute of Public Health Research, 2014
Background and Aim: Human T-Cell Lymphotropic Virus (Type I) is the cau se of two major diseases ... more Background and Aim: Human T-Cell Lymphotropic Virus (Type I) is the cau se of two major diseases : Adult T cell Leukemia-Lymphoma and Tropical Spastic Paraparasia and Myelopathy associated with HTLV-I. Disease transmis sion is possible during unsafe sexual contact, blood transfusion and vertical transmissio n method. Blood safety and minimizing the risk of transfusion transmitted infections are the main goals of blood transfusion organization. Mashhad is located in an endemic are a nd it is essential to investigate about the virus epidemiology. Materials and Methods: In this descriptive study from 1388 to 1389. all th e blood donation volunteers, who were eligible for blood donation bu t had HTLV serum positive results in both screening and confirmatory tests with Elisa an d Western Blot method, respectively, were considered as HTLV infected individuals. The i nfected group was compared with a group of healthy blood donors as a witness group. T he data were analyzed by SPSS-17 softw...
Introduction: Frozen section is mainly performed to determine malignity, so it is of fundamental ... more Introduction: Frozen section is mainly performed to determine malignity, so it is of fundamental importance to evaluate the diagnostic accuracy of frozen sections performed for each group of tissues in order to reduce false diagnoses, unnecessary surgeries and following unwanted complications. This study is conducted to evaluate the diagnostic accuracy of frozen section performed on ovary tissue compared to permanent sections. Materials and Methods: In this retrospective study, we evaluate frozen sections performed at Taleghani hospital pathology department in five years and their results were compared with permanent sections’ results to calculate sensitivity, specificity, negative predictive value and positive predictive value. In cases which results were discordant, we check for probable reasons. Results: 83 species were evaluated from patients with a mean age of 42.9 years; the smallest was 19 and the oldest was 86 years old (Std. dev: 12.84). 75 cases of frozen sections were ben...
Animal bites are serious threats to human health due to their subsequent fatal infections such as... more Animal bites are serious threats to human health due to their subsequent fatal infections such as rabies. The increasing rate of occurrences, the expanding number of animal bites and the distribution of rabies in many provinces of the country is alarming, necessitating further attention to control the disease and performing research on its different aspects. All records of animal bites referred to the clinic during 2010 to 2012 were included in this study. The obtained data were analyzed by descriptive statistics and Chi-square test. Of 1875 registered cases, 65% were men and 35% were women. The mean age of the patients was 33.18 ± 17.15 years in both genders. There was no death record due to rabies. Most of patients (97%) lived in urban areas. The highest number of bites was occurred at the age of 20‑29 years (33%) and the highest frequency of bites happened in spring (29%). There was a significant (P < 10-6) relationship between the number of bites and season, favoring spring (...
Background and Aims : Healthy People plan that is expressed by WHO stipulated that by 2000 at lea... more Background and Aims : Healthy People plan that is expressed by WHO stipulated that by 2000 at least 50% of the children and by 2010, 90% of 6-5 year-old children should be with no caries in their primary teeth. The present study investigated the prevalence of teeth decay of D, E and related factors in 6 and 7 years old children. Material and Methods: This cross-sectional study was conducted in 2013 to assess the bases covered by student Shemiranat health center. Study population including 5000 students aged 6 and 7 and the sample size of 450 patients was available in sampling method. Data in a form that was designed for this study were collected and analyzed using Epi data and SPSS software. Results: The index dmft (Decayed Missed Filled Teeth) in primary teeth D and E is equaled to 2.46 and prevalence of dental caries E and D were estimated 63.4%. There is significant relationship between decay of teeth D and E and father education (Pvalue<0.001) and mother education (Pvalue<...
Background: The rapid increase in the spread of COVID-19 and the numbers of infected patients wor... more Background: The rapid increase in the spread of COVID-19 and the numbers of infected patients worldwide has highlighted the need for intensive care unit (ICU) beds and more advanced therapy. This need is more urgent in resource-constrained settings. The present study aimed to identify the predictors of ICU admission among hospitalized COVID-19 patients. Study design: The current study was conducted based on a retrospective cohort design. Methods: The participants included 665 definite cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) hospitalized in Imam Hossein Hospital from February 20 to May 14, 2020. The baseline characteristics of patients were assessed, and multivariate logistic regression analysis was utilized to determine the significant odds ratio (OR) for ICU admission. Results: Participants were aged 59.52±16.72 years, and the majority (55.6%) of them were male. Compared to non-ICU patients (n=547), the ICU patients (n=118) were older, had more baselin...
Iranian Journal of Health Safety and Environment, Aug 3, 2014
Musculoskeletal disorders may be observed in all industries and professions and most of these dis... more Musculoskeletal disorders may be observed in all industries and professions and most of these disorders are related to the back, upper and lower extremities of the body organs. In Pharmaceutical industry, almost lack of standard ergonomic conditions and sometimes can cause outbreaks of diseases and musculoskeletal disorders in various parts of the body. The aim of this study was to determine the relationship between musculoskeletal disorders and working on the packaging section of the pharmaceutical industry. The Nordic questionnaire and Rula method were used for collection of data and 392 workers were selected as the subjects of study. Based on the results of this study, (28.5%) of workers working in Packaging Unit complained of severe pain and discomfort in their neck, (23.7%) in their shoulder, (27.9%) in their hand and wrist and (33.2%) complained of severe pain in their back. The results indicate that workers in this industry could show musculoskeletal disorders based on age, education, gender and working conductions.
BACKGROUND The diagnostic accuracy of frozen section as an important source of information in sur... more BACKGROUND The diagnostic accuracy of frozen section as an important source of information in surgical pathology is important not only in the management of surgical patients but also as a measure of quality control in surgical pathology. In this study, we evaluated the diagnostic accuracy of frozen sections over a 6-year period in a teaching hospital in Iran. METHODS We retrospectively reviewed frozen sections performed in the Pathology Department of Taleghani Hospital (Shahid Beheshti University of Medical Sciences), Tehran, Iran from 2007 to 2013. The results were compared to the permanent sections to evaluate diagnostic accuracy, sensitivity and specificity, of frozen section test. Discordant cases were reassessed to find the reasons for discrepancy. RESULTS A total of 306 frozen section specimens from 176 surgical cases were evaluated. In eleven specimens (3.59%) the diagnoses were deferred. Of the remaining 295 specimens, 6 (2.03%) were discordant and 289 (97.96%) were concorda...
Backgrounds: Coronavirus disease 2019 (COVID-19) pandemic is considered as a global health challe... more Backgrounds: Coronavirus disease 2019 (COVID-19) pandemic is considered as a global health challenge, and Iran is among the top ten countries with the highest mortality rate. This study aimed to analyze epidemiological, clinical, and laboratory features of hospitalized SARS-CoV-2 infected patients and identify the risk factors of mortality among them to facilitate the prioritization of resources and vaccine allocation in the population using data available in a large university hospital in Tehran, Iran. Materials & Methods: From February 20 to May 14, 2020, a total of 684 COVID-19 confirmed cases were admitted to Imam Hossein University hospital in Tehran and enrolled in this retrospective observational study. Findings: The mean age of the participants was 59.48±16.65 years, and 55.8% were male. Compared to survivors, non-survivors (n=127, 18.57%) were older (69.09±14.16 vs. 57.29±16.40), had higher average number of comorbidities, and more frequently suffered from dyspnea, convulsion, loss of consciousness (LOC), tachycardia, tachypnea, and hypoxia. They also had higher levels of leukocytes, neutrophil count, C-reactive protein (CRP), creatine phosphokinase (CPK), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), international normalized ratio (INR), prothrombin time (PT), partial thromboplastin time (PTT), urea, and serum creatinine (p<.05). Serum potassium (K), lymphocyte count, hemoglobin, HCO 3 , and serum sodium (Na) were significantly lower in non-survivors. Multivariable logistic regression analysis results revealed that nine variables were positively associated with mortality. Conclusion: Among COVID-19 patients admitted to the hospital, having more than two or three comorbidities, loss of consciousness, SpO2 < 90%, increased CRP, CPK, urea, and serum potassium, were associated with mortality.
Journal of School of Public Health and Institute of Public Health Research, 2014
Background and Aim: Human T-Cell Lymphotropic Virus (Type I) is the cau se of two major diseases ... more Background and Aim: Human T-Cell Lymphotropic Virus (Type I) is the cau se of two major diseases : Adult T cell Leukemia-Lymphoma and Tropical Spastic Paraparasia and Myelopathy associated with HTLV-I. Disease transmis sion is possible during unsafe sexual contact, blood transfusion and vertical transmissio n method. Blood safety and minimizing the risk of transfusion transmitted infections are the main goals of blood transfusion organization. Mashhad is located in an endemic are a nd it is essential to investigate about the virus epidemiology. Materials and Methods: In this descriptive study from 1388 to 1389. all th e blood donation volunteers, who were eligible for blood donation bu t had HTLV serum positive results in both screening and confirmatory tests with Elisa an d Western Blot method, respectively, were considered as HTLV infected individuals. The i nfected group was compared with a group of healthy blood donors as a witness group. T he data were analyzed by SPSS-17 softw...
Introduction: Frozen section is mainly performed to determine malignity, so it is of fundamental ... more Introduction: Frozen section is mainly performed to determine malignity, so it is of fundamental importance to evaluate the diagnostic accuracy of frozen sections performed for each group of tissues in order to reduce false diagnoses, unnecessary surgeries and following unwanted complications. This study is conducted to evaluate the diagnostic accuracy of frozen section performed on ovary tissue compared to permanent sections. Materials and Methods: In this retrospective study, we evaluate frozen sections performed at Taleghani hospital pathology department in five years and their results were compared with permanent sections’ results to calculate sensitivity, specificity, negative predictive value and positive predictive value. In cases which results were discordant, we check for probable reasons. Results: 83 species were evaluated from patients with a mean age of 42.9 years; the smallest was 19 and the oldest was 86 years old (Std. dev: 12.84). 75 cases of frozen sections were ben...
Animal bites are serious threats to human health due to their subsequent fatal infections such as... more Animal bites are serious threats to human health due to their subsequent fatal infections such as rabies. The increasing rate of occurrences, the expanding number of animal bites and the distribution of rabies in many provinces of the country is alarming, necessitating further attention to control the disease and performing research on its different aspects. All records of animal bites referred to the clinic during 2010 to 2012 were included in this study. The obtained data were analyzed by descriptive statistics and Chi-square test. Of 1875 registered cases, 65% were men and 35% were women. The mean age of the patients was 33.18 ± 17.15 years in both genders. There was no death record due to rabies. Most of patients (97%) lived in urban areas. The highest number of bites was occurred at the age of 20‑29 years (33%) and the highest frequency of bites happened in spring (29%). There was a significant (P < 10-6) relationship between the number of bites and season, favoring spring (...
Background and Aims : Healthy People plan that is expressed by WHO stipulated that by 2000 at lea... more Background and Aims : Healthy People plan that is expressed by WHO stipulated that by 2000 at least 50% of the children and by 2010, 90% of 6-5 year-old children should be with no caries in their primary teeth. The present study investigated the prevalence of teeth decay of D, E and related factors in 6 and 7 years old children. Material and Methods: This cross-sectional study was conducted in 2013 to assess the bases covered by student Shemiranat health center. Study population including 5000 students aged 6 and 7 and the sample size of 450 patients was available in sampling method. Data in a form that was designed for this study were collected and analyzed using Epi data and SPSS software. Results: The index dmft (Decayed Missed Filled Teeth) in primary teeth D and E is equaled to 2.46 and prevalence of dental caries E and D were estimated 63.4%. There is significant relationship between decay of teeth D and E and father education (Pvalue<0.001) and mother education (Pvalue<...
Background: The rapid increase in the spread of COVID-19 and the numbers of infected patients wor... more Background: The rapid increase in the spread of COVID-19 and the numbers of infected patients worldwide has highlighted the need for intensive care unit (ICU) beds and more advanced therapy. This need is more urgent in resource-constrained settings. The present study aimed to identify the predictors of ICU admission among hospitalized COVID-19 patients. Study design: The current study was conducted based on a retrospective cohort design. Methods: The participants included 665 definite cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) hospitalized in Imam Hossein Hospital from February 20 to May 14, 2020. The baseline characteristics of patients were assessed, and multivariate logistic regression analysis was utilized to determine the significant odds ratio (OR) for ICU admission. Results: Participants were aged 59.52±16.72 years, and the majority (55.6%) of them were male. Compared to non-ICU patients (n=547), the ICU patients (n=118) were older, had more baselin...
Iranian Journal of Health Safety and Environment, Aug 3, 2014
Musculoskeletal disorders may be observed in all industries and professions and most of these dis... more Musculoskeletal disorders may be observed in all industries and professions and most of these disorders are related to the back, upper and lower extremities of the body organs. In Pharmaceutical industry, almost lack of standard ergonomic conditions and sometimes can cause outbreaks of diseases and musculoskeletal disorders in various parts of the body. The aim of this study was to determine the relationship between musculoskeletal disorders and working on the packaging section of the pharmaceutical industry. The Nordic questionnaire and Rula method were used for collection of data and 392 workers were selected as the subjects of study. Based on the results of this study, (28.5%) of workers working in Packaging Unit complained of severe pain and discomfort in their neck, (23.7%) in their shoulder, (27.9%) in their hand and wrist and (33.2%) complained of severe pain in their back. The results indicate that workers in this industry could show musculoskeletal disorders based on age, education, gender and working conductions.
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Papers by Hossein Hatami