Papers by Haupt Heinz-Gerhard
Gesundheitswesen, 2009
The therapy of the chronic tinnitus is aimed at improving the way patients cope with their tinnit... more The therapy of the chronic tinnitus is aimed at improving the way patients cope with their tinnitus and at reducing the tinnitus-related distress. The present study investigated the changes of psychometric parameters that occurred in patients with chronic tinnitus after 7-days outpatient multidisciplinary therapy. The changes were monitored for up to 1 year in order to evaluate the long-term efficiency. Main emphasis of the intensive tinnitus therapy applied was placed on tinnitus habituation and on teaching the patients how to apply coping strategies. The main elements of the multimodal concept included progressive muscle relaxation according to Jacobson, physiotherapy, educative seminars, training of selective attention and, lastly, the change of judgment, attitude and behaviour towards tinnitus. Psychometric parameters and tinnitus-related distress were assessed prior to and after the therapy (at 3, 6 and 12 months) using the tinnitus questionnaire (TQ) according to Goebel and Hiller. Furthermore, subjects waiting for therapy (waiting list) were recruited to the control group and compared with the therapy group which had received therapy 3 months earlier. The therapy group showed a significant reduction of the TQ total score after 3 months as compared to the control group. Moreover, we observed a long-term, progressive positive outcome during the one-year follow-up. The TQ total score was reduced by 10.9 points. There was an obvious decrease of the emotional and cognitive distress as well as of the intrusiveness of tinnitus, as per evaluation of TQ subscales. The outpatient intensive multidisciplinary tinnitus therapy with long-term aftercare has proved to be an effective method in the treatment of patients with chronic tinnitus. The outpatient setting enables the instant implementation of strategies learned during therapy in the patients' everyday life.
Human Genetics, 1968
A congenital failure of β2-glycoprotein is described. Whereas in the blood of normal donors 20 mg... more A congenital failure of β2-glycoprotein is described. Whereas in the blood of normal donors 20 mg of this protein per 100 ml serum are proved by quantitative immunological methods, a total lack of β2-glycoprotein was found with two members of the family in question and the serum of five others contains only half of the normal amount (7–11 mg per 100 ml). Es wird über einen erblichen Mangel an β2-Glykoprotein I berichtet. Dieses Protein, dessen Gehalt im Serum gesunder Blutspender nach quantitativen immunologischen Bestimmungen 20 mg/100 ml beträgt, fehlt bei 2 Mitgliedern der untersuchten Familien vollständig und ist im Serum von 5 weiteren Familienmitgliedern auf die Hälfte (7–11 mg/100 ml) verringert.
Cephalalgia, 2011
To assess bone regeneration in critical sized defects in the rabbit calvarium, filled with the bo... more To assess bone regeneration in critical sized defects in the rabbit calvarium, filled with the bone substitute calcium phosphate cement. Circular bone defects (8mm) were made in both parietal bones of 10 rabbits. One of the defects was filled with the calcium phosphate cement, and the other received autogenous bone harvested from the calvaria. The animals were killed at 3 or 6 weeks (n=5). Data analysis included qualitative assessment of the calvarial specimens and histomorphometric analysis was used to quantify the amount of new bone within the defects. The microscopic analysis of the samples showed bone healing with both calcium phosphate cement and autogenous bone graft. Data obtained from the histomorphometric analysis were statistically analyzed using 2-way analysis of variance and the Tukey's test. Data analysis showed that the autogenous bone graft had significantly more new bone compared with calcium phosphate cement at 3 and 6 weeks. Calcium phosphate cement at 6 weeks presented similar results to autogenous bone at 3 weeks. Both treatments presented an increase in bone healing with time. Treatments allowed bone regeneration that increased with time, however surgical cavities treated with the autogenous graft had more bone formation than those with calcium phosphate cement.
Proceedings of The National Academy of Sciences, 1988
Complete amino acid sequence of human plasma Zn-a2-glycoprotein and its homology to histocompatib... more Complete amino acid sequence of human plasma Zn-a2-glycoprotein and its homology to histocompatibility antigens (plasma protein structure/glycan structure//HLA dass I antigens/secretory major histocompatibility complex-related protein/immnnoglobuiln gene superfamily)
Human Genetics, 1968
A congenital failure of β2-glycoprotein is described. Whereas in the blood of normal donors 20 mg... more A congenital failure of β2-glycoprotein is described. Whereas in the blood of normal donors 20 mg of this protein per 100 ml serum are proved by quantitative immunological methods, a total lack of β2-glycoprotein was found with two members of the family in question and the serum of five others contains only half of the normal amount (7–11 mg per 100 ml). Es wird über einen erblichen Mangel an β2-Glykoprotein I berichtet. Dieses Protein, dessen Gehalt im Serum gesunder Blutspender nach quantitativen immunologischen Bestimmungen 20 mg/100 ml beträgt, fehlt bei 2 Mitgliedern der untersuchten Familien vollständig und ist im Serum von 5 weiteren Familienmitgliedern auf die Hälfte (7–11 mg/100 ml) verringert.
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Papers by Haupt Heinz-Gerhard