
Hamza Yakubu
I am graduate of Industrial Chemistry with strong passion for pharmaceutical research.
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Drafts by Hamza Yakubu
phytochemicals or secondary metabolites and antibacterial activity of its root and stem bark were
studied in this research work. The phytochemical screening of the plant was carried out using
standard methods of analysis and these investigations revealed the presence of bioactive
components comprising flavonoids, alkaloids, saponins, steroids, terpenoids, glycosides and
phenols while tannins were not detected in both the root and stem bark of the plant. The plant
was extracted with water and 100% methanol via cold maceration method and the extracts were
subjected to antibacterial activities using the agar plate disc diffusion and nutrient broth dilution
techniques. against E. coli, S. aureus and Shigella spp to ascertain its medicinal and therapeutic
properties at various concentrations range from 50 mg/mL – 6.25 mg/mL. From the study it was
observed that the stem bark extract has the higher antibacterial activity against E. coli and
Shigella spp with mean zone of inhibition of 18.50 ± 0.02 and 14.10 ± 0.12 mm while the root
recorded the higher antibacterial activity against S.aureus with mean zone of inhibition of 16.37
± 0.07 mm. The result indicates that the extracts of the root and stem bark of this plant possess
antibacterial activities.
Papers by Hamza Yakubu
phytochemicals or secondary metabolites and antibacterial activity of its root and stem bark were
studied in this research work. The phytochemical screening of the plant was carried out using
standard methods of analysis and these investigations revealed the presence of bioactive
components comprising flavonoids, alkaloids, saponins, steroids, terpenoids, glycosides and
phenols while tannins were not detected in both the root and stem bark of the plant. The plant
was extracted with water and 100% methanol via cold maceration method and the extracts were
subjected to antibacterial activities using the agar plate disc diffusion and nutrient broth dilution
techniques. against E. coli, S. aureus and Shigella spp to ascertain its medicinal and therapeutic
properties at various concentrations range from 50 mg/mL – 6.25 mg/mL. From the study it was
observed that the stem bark extract has the higher antibacterial activity against E. coli and
Shigella spp with mean zone of inhibition of 18.50 ± 0.02 and 14.10 ± 0.12 mm while the root
recorded the higher antibacterial activity against S.aureus with mean zone of inhibition of 16.37
± 0.07 mm. The result indicates that the extracts of the root and stem bark of this plant possess
antibacterial activities.