This study examines voice perturbation parameters of the sustained [ɑ] in English and of the eigh... more This study examines voice perturbation parameters of the sustained [ɑ] in English and of the eight vowels in Turkish to discover whether any difference exists between these languages, and whether a correlation exists between voice perturbation parameters and articulatory and acoustic properties of the Turkish vowels. Eight Turkish vowels uttered by 26 healthy nonsmoker volunteer males who are native Turkish speakers were compared with a voice database that includes samples of normal and disordered voices belonging to American English speakers. Fundamental frequencies, the first and second formants, and perturbation parameters, such as jitter percent, pitch perturbation quotient, shimmer percent, and amplitude perturbation quotient of the sustained vowels, were measured. Also, the first and second formants of the sustained [ɑ] in English were measured, and other parameters have been obtained from the database. When the voice perturbation parameters in Turkish and English were compared, statistically significant differences were not found. However, when Turkish vowels compared with each other, statistically significant differences were found among perturbation values. Categorical comparisons of the Turkish vowels like high-low, rounded-unrounded, and front-back revealed significant differences in perturbation values. In correlation analysis, a weak linear inverse relation between jitter percent and the first formant (r ϭ Ϫ0.260, p Ͻ 0.05) was found.
Treatment of glottic insufficiency; medialization laryngoplasty: short and long term results Obje... more Treatment of glottic insufficiency; medialization laryngoplasty: short and long term results Objectives: The aim of this study is to evaluate short and long term results, preoperative and postoperative perceptual voice analysis, videolarygostroboscopic findings, objective acoustic analysis and aerodynamic measures of medialization laryngoplasty procedure. Methods: Sixteen patients, who had undergone medialization laryngoplasty with carved silicon implant between 1998 and 2004 in
Purpose: The purpose of this study was to investigate the early and long-term functional results ... more Purpose: The purpose of this study was to investigate the early and long-term functional results of thyroplasty type-I and injection laryngoplasty using fat or calcium hydroxylapatite. Materials and methods: Thirty patients with glottic insufficiency were included and followed up between 1-7 years. Patients with glottic bowing or sulcus vocalis were selected for injection augmentation of the vocal folds, while those with unilateral vocal fold immobility underwent medialization thyroplasty. Perceptual and acoustic analysis of voice, and videolaryngostroboscopy were performed before and after surgery. Results: After the surgery, GRBAS scale of all patients demonstrated significant change in grade of severity, roughness, and breathiness. Acoustic analysis demonstrated significant change in Fo, jitter, shimmer, noise to harmonic ratio, and maximum phonation time (MPT) in thyroplasty group, while those demonstrated significant change in Fo (lowest) and jitter, and MPT in injection augmentation group. Conclusions: Medialization thyroplasty is the gold standard for the management of glottic insufficiency, regardless of the severity of glottic gap. However, injection augmentation of the vocal folds may be considered as an alternative in the treatment of patients with small glottic gap. Further studies with larger groups and long follow-up periods are required to figure out the proper material for injection laryngoplasty. D
Background. Many methods of glottic reconstruction have been described for patients undergoing ve... more Background. Many methods of glottic reconstruction have been described for patients undergoing vertical partial laryngectomy to reestablish the glottic integrity.
We conducted a study to examine six macroscopic features of vocal fold polyps and to investigate ... more We conducted a study to examine six macroscopic features of vocal fold polyps and to investigate their influence on quality of voice. We retrospectively reviewed the records of 101 consecutive patients with vocal fold polyps who had undergone microlaryngeal surgery for polyp removal after conservative measures had failed. All patients had undergone videolaryngostroboscopy and perceptual and acoustic voice analyses. The six macroscopic features of these vocal fold polyps were morphologic type, location, position, shape, size, and the presence or absence of a reactive lesion on the contralateral vocal fold. Among our statistically significant findings were that gelatinous polyps tended to be broad-based; polyps located on the superior surface tended to be hemorrhagic; small polyps were mostly located on the middle one-third of the vocal fold, and most of them were broad-based; and all of the polyps that were accompanied by reactive lesions on the contralateral vocal fold were located ...
We conducted a study to examine six macroscopic features of vocal fold polyps and to investigate ... more We conducted a study to examine six macroscopic features of vocal fold polyps and to investigate their influence on quality of voice. We retrospectively reviewed the records of 101 consecutive patients with vocal fold polyps who had undergone microlaryngeal surgery for polyp removal after conservative measures had failed. All patients had undergone videolaryngostroboscopy and perceptual and acoustic voice analyses. The six macroscopic features of these vocal fold polyps were morphologic type, location, position, shape, size, and the presence or absence of a reactive lesion on the contralateral vocal fold. Among our statistically significant findings were that gelatinous polyps tended to be broad-based; polyps located on the superior surface tended to be hemorrhagic; small polyps were mostly located on the middle one-third of the vocal fold, and most of them were broad-based; and all of the polyps that were accompanied by reactive lesions on the contralateral vocal fold were located ...
Laryngeal cysts are rare in adults; therefore, the majority of previous reports deal primarily wi... more Laryngeal cysts are rare in adults; therefore, the majority of previous reports deal primarily with laryngeal cysts in infants and children. Ductal cysts of the larynx arise from the submucous glands when the ducts of these glands are occluded. They are most commonly located in the vallecula. In this report, we present a rare cause of life-threatening stridor in adults, a large ductal cyst of the larynx that was removed via endoscopic CO(2) laser resection. On the basis of clinical observations during the postoperative period, we conclude that endoscopic CO(2) laser resection is a reliable and safe method for removing cysts of the larynx. It is also a cost-effective procedure that minimizes hospitalization time and the need for tracheotomy.
We conducted a prospective study to investigate the long-term effect of nasal airflow deprivation... more We conducted a prospective study to investigate the long-term effect of nasal airflow deprivation on nasal dimensions after total laryngectomy. We evaluated 48 patients who had an initial diagnosis of laryngeal cancer; 6 were disqualified during follow-up, leaving us with data on 42 patients for our final analysis. Acoustic rhinometry was used to measure the minimum cross-sectional area (MCSA) and the volume of the nasal cavity on both the left and right sides before and after laryngectomy. In addition, patients underwent endoscopic nasal examinations and answered questionnaires pre- and postoperatively. At both the 1- and 2-year follow-ups, the mean MCSAs and the mean nasal volumes of both the left and right nostrils were significantly smaller than the preoperative values (p < 0.001). The endoscopic examinations revealed only a mild deterioration in the appearance of the nasal mucosa over the long term. Questionnaire responses obtained at the 2-year follow-up visit revealed that...
Kulak Burun Bogaz Ihtisas Dergisi Kbb Journal of Ear Nose and Throat, Feb 1, 2007
A 75-year-old female patient presented with hoarseness and foreign body sensation in the back of ... more A 75-year-old female patient presented with hoarseness and foreign body sensation in the back of her throat of one-month history. Direct laryngoscopy showed bilateral, yellow, hyperemic masses on the left false vocal fold and laryngeal ventricle. Both true vocal folds were mobile. Excisional biopsies of the right false vocal fold and ventricle showed extracellular, insoluble, fibrillar protein accumulation, consistent with amyloidosis. There was no evidence for neoplasm. Serum and urine electrophoreses were negative. The work-up for systemic amyloidosis and multiple myeloma were negative. Treatment was limited to surgical excision. No complications developed within a six-month follow-up period.
Turkiye Klinikleri Journal of Medical Sciences, 2012
ABSTRACT Objective: The aim of this study was to investigate which diagnostic method was more eff... more ABSTRACT Objective: The aim of this study was to investigate which diagnostic method was more efficient and reliable for preoperative T staging of laryngeal cancers by comparing videolaryn-gostroboscopy (VLS) and computed tomography (CT) findings with histopathologic examination of operation specimens. The main goal was to determine the most rational and accurate approach for preoperative evaluation and staging of larynx cancers. Material and Methods: This retrospective study included 58 patients operated on for larynx cancer. Preoperative VLS and CT findings were compared with histopathologic examination results of the operation specimens. The larynx was di-vided into 12 anatomical areas for this purpose. In addition, thyroid and cricoid cartilage invasion and extralaryngeal invasion parameters were included in the evaluation. Invasion of the tumor was identified by each evaluation method separately. Mobility of the vocal cords and arytenoids was evaluated with VLS. Results: CT was more effective than VLS in the evaluation of the paraglottic area, preepiglottic area, and subglottic area. CT was superior to VLS for the identification of thy-roid involvement, cricoid cartilages and extralaryngeal invasion. VLS was more effective than CT for the assessment of the vocal cords and anterior commissure. Both diagnostic methods were ef-fective for identification of tumor on the epiglottis. Conclusion: Success of VLS and CT changes ac-cording to the involvement of different anatomic areas. A combination of VLS and CT together, while taking into consideration the location of the tumor, improves accurate staging and conse-quently the surgical success.
Background. Many methods of glottic reconstruction have been described for patients undergoing ve... more Background. Many methods of glottic reconstruction have been described for patients undergoing vertical partial laryngectomy to reestablish the glottic integrity.
Purpose: The purpose of this study was to investigate the early and long-term functional results ... more Purpose: The purpose of this study was to investigate the early and long-term functional results of thyroplasty type-I and injection laryngoplasty using fat or calcium hydroxylapatite. Materials and methods: Thirty patients with glottic insufficiency were included and followed up between 1-7 years. Patients with glottic bowing or sulcus vocalis were selected for injection augmentation of the vocal folds, while those with unilateral vocal fold immobility underwent medialization thyroplasty. Perceptual and acoustic analysis of voice, and videolaryngostroboscopy were performed before and after surgery. Results: After the surgery, GRBAS scale of all patients demonstrated significant change in grade of severity, roughness, and breathiness. Acoustic analysis demonstrated significant change in Fo, jitter, shimmer, noise to harmonic ratio, and maximum phonation time (MPT) in thyroplasty group, while those demonstrated significant change in Fo (lowest) and jitter, and MPT in injection augmentation group. Conclusions: Medialization thyroplasty is the gold standard for the management of glottic insufficiency, regardless of the severity of glottic gap. However, injection augmentation of the vocal folds may be considered as an alternative in the treatment of patients with small glottic gap. Further studies with larger groups and long follow-up periods are required to figure out the proper material for injection laryngoplasty. D
This study examines voice perturbation parameters of the sustained [ɑ] in English and of the eigh... more This study examines voice perturbation parameters of the sustained [ɑ] in English and of the eight vowels in Turkish to discover whether any difference exists between these languages, and whether a correlation exists between voice perturbation parameters and articulatory and acoustic properties of the Turkish vowels. Eight Turkish vowels uttered by 26 healthy nonsmoker volunteer males who are native Turkish speakers were compared with a voice database that includes samples of normal and disordered voices belonging to American English speakers. Fundamental frequencies, the first and second formants, and perturbation parameters, such as jitter percent, pitch perturbation quotient, shimmer percent, and amplitude perturbation quotient of the sustained vowels, were measured. Also, the first and second formants of the sustained [ɑ] in English were measured, and other parameters have been obtained from the database. When the voice perturbation parameters in Turkish and English were compared, statistically significant differences were not found. However, when Turkish vowels compared with each other, statistically significant differences were found among perturbation values. Categorical comparisons of the Turkish vowels like high-low, rounded-unrounded, and front-back revealed significant differences in perturbation values. In correlation analysis, a weak linear inverse relation between jitter percent and the first formant (r ϭ Ϫ0.260, p Ͻ 0.05) was found.
Treatment of glottic insufficiency; medialization laryngoplasty: short and long term results Obje... more Treatment of glottic insufficiency; medialization laryngoplasty: short and long term results Objectives: The aim of this study is to evaluate short and long term results, preoperative and postoperative perceptual voice analysis, videolarygostroboscopic findings, objective acoustic analysis and aerodynamic measures of medialization laryngoplasty procedure. Methods: Sixteen patients, who had undergone medialization laryngoplasty with carved silicon implant between 1998 and 2004 in
Purpose: The purpose of this study was to investigate the early and long-term functional results ... more Purpose: The purpose of this study was to investigate the early and long-term functional results of thyroplasty type-I and injection laryngoplasty using fat or calcium hydroxylapatite. Materials and methods: Thirty patients with glottic insufficiency were included and followed up between 1-7 years. Patients with glottic bowing or sulcus vocalis were selected for injection augmentation of the vocal folds, while those with unilateral vocal fold immobility underwent medialization thyroplasty. Perceptual and acoustic analysis of voice, and videolaryngostroboscopy were performed before and after surgery. Results: After the surgery, GRBAS scale of all patients demonstrated significant change in grade of severity, roughness, and breathiness. Acoustic analysis demonstrated significant change in Fo, jitter, shimmer, noise to harmonic ratio, and maximum phonation time (MPT) in thyroplasty group, while those demonstrated significant change in Fo (lowest) and jitter, and MPT in injection augmentation group. Conclusions: Medialization thyroplasty is the gold standard for the management of glottic insufficiency, regardless of the severity of glottic gap. However, injection augmentation of the vocal folds may be considered as an alternative in the treatment of patients with small glottic gap. Further studies with larger groups and long follow-up periods are required to figure out the proper material for injection laryngoplasty. D
Background. Many methods of glottic reconstruction have been described for patients undergoing ve... more Background. Many methods of glottic reconstruction have been described for patients undergoing vertical partial laryngectomy to reestablish the glottic integrity.
We conducted a study to examine six macroscopic features of vocal fold polyps and to investigate ... more We conducted a study to examine six macroscopic features of vocal fold polyps and to investigate their influence on quality of voice. We retrospectively reviewed the records of 101 consecutive patients with vocal fold polyps who had undergone microlaryngeal surgery for polyp removal after conservative measures had failed. All patients had undergone videolaryngostroboscopy and perceptual and acoustic voice analyses. The six macroscopic features of these vocal fold polyps were morphologic type, location, position, shape, size, and the presence or absence of a reactive lesion on the contralateral vocal fold. Among our statistically significant findings were that gelatinous polyps tended to be broad-based; polyps located on the superior surface tended to be hemorrhagic; small polyps were mostly located on the middle one-third of the vocal fold, and most of them were broad-based; and all of the polyps that were accompanied by reactive lesions on the contralateral vocal fold were located ...
We conducted a study to examine six macroscopic features of vocal fold polyps and to investigate ... more We conducted a study to examine six macroscopic features of vocal fold polyps and to investigate their influence on quality of voice. We retrospectively reviewed the records of 101 consecutive patients with vocal fold polyps who had undergone microlaryngeal surgery for polyp removal after conservative measures had failed. All patients had undergone videolaryngostroboscopy and perceptual and acoustic voice analyses. The six macroscopic features of these vocal fold polyps were morphologic type, location, position, shape, size, and the presence or absence of a reactive lesion on the contralateral vocal fold. Among our statistically significant findings were that gelatinous polyps tended to be broad-based; polyps located on the superior surface tended to be hemorrhagic; small polyps were mostly located on the middle one-third of the vocal fold, and most of them were broad-based; and all of the polyps that were accompanied by reactive lesions on the contralateral vocal fold were located ...
Laryngeal cysts are rare in adults; therefore, the majority of previous reports deal primarily wi... more Laryngeal cysts are rare in adults; therefore, the majority of previous reports deal primarily with laryngeal cysts in infants and children. Ductal cysts of the larynx arise from the submucous glands when the ducts of these glands are occluded. They are most commonly located in the vallecula. In this report, we present a rare cause of life-threatening stridor in adults, a large ductal cyst of the larynx that was removed via endoscopic CO(2) laser resection. On the basis of clinical observations during the postoperative period, we conclude that endoscopic CO(2) laser resection is a reliable and safe method for removing cysts of the larynx. It is also a cost-effective procedure that minimizes hospitalization time and the need for tracheotomy.
We conducted a prospective study to investigate the long-term effect of nasal airflow deprivation... more We conducted a prospective study to investigate the long-term effect of nasal airflow deprivation on nasal dimensions after total laryngectomy. We evaluated 48 patients who had an initial diagnosis of laryngeal cancer; 6 were disqualified during follow-up, leaving us with data on 42 patients for our final analysis. Acoustic rhinometry was used to measure the minimum cross-sectional area (MCSA) and the volume of the nasal cavity on both the left and right sides before and after laryngectomy. In addition, patients underwent endoscopic nasal examinations and answered questionnaires pre- and postoperatively. At both the 1- and 2-year follow-ups, the mean MCSAs and the mean nasal volumes of both the left and right nostrils were significantly smaller than the preoperative values (p < 0.001). The endoscopic examinations revealed only a mild deterioration in the appearance of the nasal mucosa over the long term. Questionnaire responses obtained at the 2-year follow-up visit revealed that...
Kulak Burun Bogaz Ihtisas Dergisi Kbb Journal of Ear Nose and Throat, Feb 1, 2007
A 75-year-old female patient presented with hoarseness and foreign body sensation in the back of ... more A 75-year-old female patient presented with hoarseness and foreign body sensation in the back of her throat of one-month history. Direct laryngoscopy showed bilateral, yellow, hyperemic masses on the left false vocal fold and laryngeal ventricle. Both true vocal folds were mobile. Excisional biopsies of the right false vocal fold and ventricle showed extracellular, insoluble, fibrillar protein accumulation, consistent with amyloidosis. There was no evidence for neoplasm. Serum and urine electrophoreses were negative. The work-up for systemic amyloidosis and multiple myeloma were negative. Treatment was limited to surgical excision. No complications developed within a six-month follow-up period.
Turkiye Klinikleri Journal of Medical Sciences, 2012
ABSTRACT Objective: The aim of this study was to investigate which diagnostic method was more eff... more ABSTRACT Objective: The aim of this study was to investigate which diagnostic method was more efficient and reliable for preoperative T staging of laryngeal cancers by comparing videolaryn-gostroboscopy (VLS) and computed tomography (CT) findings with histopathologic examination of operation specimens. The main goal was to determine the most rational and accurate approach for preoperative evaluation and staging of larynx cancers. Material and Methods: This retrospective study included 58 patients operated on for larynx cancer. Preoperative VLS and CT findings were compared with histopathologic examination results of the operation specimens. The larynx was di-vided into 12 anatomical areas for this purpose. In addition, thyroid and cricoid cartilage invasion and extralaryngeal invasion parameters were included in the evaluation. Invasion of the tumor was identified by each evaluation method separately. Mobility of the vocal cords and arytenoids was evaluated with VLS. Results: CT was more effective than VLS in the evaluation of the paraglottic area, preepiglottic area, and subglottic area. CT was superior to VLS for the identification of thy-roid involvement, cricoid cartilages and extralaryngeal invasion. VLS was more effective than CT for the assessment of the vocal cords and anterior commissure. Both diagnostic methods were ef-fective for identification of tumor on the epiglottis. Conclusion: Success of VLS and CT changes ac-cording to the involvement of different anatomic areas. A combination of VLS and CT together, while taking into consideration the location of the tumor, improves accurate staging and conse-quently the surgical success.
Background. Many methods of glottic reconstruction have been described for patients undergoing ve... more Background. Many methods of glottic reconstruction have been described for patients undergoing vertical partial laryngectomy to reestablish the glottic integrity.
Purpose: The purpose of this study was to investigate the early and long-term functional results ... more Purpose: The purpose of this study was to investigate the early and long-term functional results of thyroplasty type-I and injection laryngoplasty using fat or calcium hydroxylapatite. Materials and methods: Thirty patients with glottic insufficiency were included and followed up between 1-7 years. Patients with glottic bowing or sulcus vocalis were selected for injection augmentation of the vocal folds, while those with unilateral vocal fold immobility underwent medialization thyroplasty. Perceptual and acoustic analysis of voice, and videolaryngostroboscopy were performed before and after surgery. Results: After the surgery, GRBAS scale of all patients demonstrated significant change in grade of severity, roughness, and breathiness. Acoustic analysis demonstrated significant change in Fo, jitter, shimmer, noise to harmonic ratio, and maximum phonation time (MPT) in thyroplasty group, while those demonstrated significant change in Fo (lowest) and jitter, and MPT in injection augmentation group. Conclusions: Medialization thyroplasty is the gold standard for the management of glottic insufficiency, regardless of the severity of glottic gap. However, injection augmentation of the vocal folds may be considered as an alternative in the treatment of patients with small glottic gap. Further studies with larger groups and long follow-up periods are required to figure out the proper material for injection laryngoplasty. D
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