Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, Jan 20, 2016
Adrenal venous sampling (AVS) is the only available method to distinguish bilateral from unilater... more Adrenal venous sampling (AVS) is the only available method to distinguish bilateral from unilateral primary aldosteronism (PA). AVS has several drawbacks, so it is reasonable to avoid this procedure when it would not affect clinical management. Our objective was to identify a clinical criterion that can reliably predict nonlateralized AVS as a surrogate for bilateral PA which is not treated surgically. A retrospective diagnostic cross-sectional study conducted at Slovenian national endocrine referral centre included 69 consecutive patients (mean age 56±8 years; 21 females) with PA that underwent AVS. PA was confirmed with the saline infusion test (SIT). AVS was performed sequentially during continuous ACTH infusion. Main outcome measures were variables associated with nonlateralized AVS to derive a clinical prediction rule. 67 patients (97%) had a successful AVS and were included in the statistical analysis. A total of 39 patients (58%) had nonlateralized AVS. The combined criterion...
Prispevek obravnava nekatera temeljna vprašanja, s katerimi se srečujejo raziskovalci na področju... more Prispevek obravnava nekatera temeljna vprašanja, s katerimi se srečujejo raziskovalci na področju strojnega učenja pri načrtovanju in statistični analizi eksperimentalnih študij. Po pregledu najpogostejših pomanjkljivosti in napak pri uporabi statističnih metod za medsebojno primerjavo klasifikacijskih algoritmov so podrobneje obravnavani relevantni statistični testi in eksperimentalni načrti. Kot primer nadgradnje teoretičnih osnov je prikazana uporaba Bonferronijevega popravka pri gradnji odločitvenih dreves, v zaključku pa je podanih nekaj dilem v zvezi z medsebojno primerjava napovedne uspešnosti regresijskih dreves.
To evaluate effectiveness of fall-risk-assessment-based fall prevention for stroke rehabilitation... more To evaluate effectiveness of fall-risk-assessment-based fall prevention for stroke rehabilitation inpatients. A consecutive series of 232 patients admitted for the first time to a subacute stroke-rehabilitation ward during 2010-2011 was studied in detail. The Assessment Sheet for Fall Prediction in Stroke Inpatients (ASFPSI by Nakagawa et al.) was used to assess fall-risk upon admission. Association of ASFPSI score and patient characteristics with actual falls was statistically tested. Yearly incidence of falls per 1000 hospital days (HD) was retrospectively audited for the 2006-2014 period to evaluate effectiveness of fall-risk reduction measures. The observed incidence of falls over the detailed-study-period was 3.0/1000 HD; 39% of the fallers fell during the first week after admission. ASFPSI score was not significantly associated with falls. Longer hospital stay, left body-side affected and non-extreme FIM score (55-101) were associated with higher odds of fall. Introduction of fall-risk reduction measures followed by compulsory fall-risk assessment lead to incidence of falls dropping from 7.1/1000 HD in 2006 to 2.8/1000 HD in 2011 and remaining at that level until 2014. The fall-risk-assessment-based measures appear to have led to decreasing falls risk among post-stroke rehabilitation inpatients classified as being at high risk of falls. The fall prevention programme as a whole was successful. Patients with non-extreme level of functional independence should receive enhanced fall prevention. Implications for Rehabilitation Recognising the fall risk upon the patient's admission is essential for preventing falls in rehabilitation wards. Assessing the fall risk is a team tasks and combines information from various sources. Assessing fall risk in stroke patients using the assessment sheet by Nakagawa et al. immediately upon admission systematically draws attention to the risk of falls in each individual patient.
Povzetek: Članek izhaja iz prenosa spoznanj Bandurove socialne kognitivne teorije v delovno praks... more Povzetek: Članek izhaja iz prenosa spoznanj Bandurove socialne kognitivne teorije v delovno prakso v podjetju.
Prispevek obravnava nekatera temeljna vprašanja, s katerimi se srečujejo raziskovalci na področju... more Prispevek obravnava nekatera temeljna vprašanja, s katerimi se srečujejo raziskovalci na področju strojnega učenja pri načrtovanju in statistični analizi eksperimentalnih študij. Po pregledu najpogostejših pomanjkljivosti in napak pri uporabi statističnih metod za medsebojno primerjavo klasifikacijskih algoritmov so podrobneje obravnavani relevantni statistični testi in eksperimentalni načrti. Kot primer nadgradnje teoretičnih osnov je prikazana uporaba Bonferronijevega popravka pri gradnji odločitvenih dreves, v zaključku pa je podanih nekaj dilem v zvezi z medsebojno primerjava napovedne uspešnosti regresijskih dreves.
Izvleček Podpora kliničnemu odločanju je ena od naprednejših, a premalo uporabljanih funkcij klin... more Izvleček Podpora kliničnemu odločanju je ena od naprednejših, a premalo uporabljanih funkcij kliničnih informacijskih sistemov. Teava pri uvajanju tovrstnih pripomočkov je predvsem potreba po uporabi računalniške opreme, ki pa mnogokrat ni dosegljiva na mestu dejanskega odločanja, npr. na vizitah, ob pogovorih s pacientom, ipd. V članku podajamo mono rešitev tega problema v obliki lupine za pomoč pri odločanju, ki deluje
Excel is the most widespread and the most powerful general-purpose spreadsheet software, but it i... more Excel is the most widespread and the most powerful general-purpose spreadsheet software, but it is not popular with statisticians. Nevertheless, as a natural means for organising, displaying and analysing large amounts of data, spreadsheets keep gaining importance in statistical education and practice. Aiming at improving such practice rather than fruitlessly and indiscriminately condemning it, the paper provides general considerations on the topic, pointers to the huge body of relevant literature and software, and several concrete examples of data visualisation in Excel in the sense of univariate, bivariate and multivariate distribution plotting. Original and improved Excel solutions for producing dot-density plots, dot plots, stem-and-leaf plots, windowgrams, coplots and parallel coordinates plots are presented, as well as for performing the Box-Cox transformation. Additionally, further possibilities opening with the forthcoming Excel 2007 version, use of various commercial and freeware add-ins, and integration of Excel with statistical software are discussed.
The study examined age and sex differences in social anxiety in different periods of adolescence ... more The study examined age and sex differences in social anxiety in different periods of adolescence and the relations between adolescents' social anxiety, self-consciousness and perception of self-incompetence. A new measure for assessing social anxi-ety in adolescence was constructed for this purpose. 325 subjects participated in the study: early (age 12), middle (age 16) and late (age 20) adolescents answered 36 test iterns of the newly developed Social Anxiety Scale for Adolescents (SASA) and were administered measures of self-consciousness (lmaginary Audience Scale, Self-Consciousness Scale) and perceived in-competence (Perceived lncompetence Scale, Perceived Sociallncompetence Scale). Factor analysis yielded two social anxiety factors: Apprehension and Fear ofNegative Evaluation decreased with adolescents' age and was more present in females than males, while Tension and Inhibition in Social Contacts did not differentiate either between the three age groups or between sexe...
A heat-map type of chart for depicting large number of cases and up to twenty-five categorical va... more A heat-map type of chart for depicting large number of cases and up to twenty-five categorical variables with spreadsheet software is presented. It is implemented in Microsoft ® Excel using standard formulas, sorting and simple VBA code. The motivating example depicts accuracy of automated assignment of MeSH ® descriptor headings to abstracts of medical articles. Within each abstract, predicted support for each heading is ranked, then for each heading actually assigned/non-assigned by human specialist (depicted by black/white cell), high/low support is depicted on nine-point two-colour scale. Thus, each case (abstract) is depicted by one row of a table and each variable (heading) with two adjacent columns. Rank-based classification accuracy measure is calculated for each case, and rows are sorted in increasing accuracy order downwards. Based on analogous measure, variables are sorted in increasing prediction accuracy order rightwards. Another biomedical dataset is presented with a similar chart. Different methods for predicting binary outcomes can be visualised, and the procedure is easily extended to polytomous variables. 6 ASSUME, the Association of Statistics Specialists Using Microsoft Excel, provides a starting point for an overview at
Prosthetics and orthotics international, Jan 28, 2015
Little is known about secondary impairments and overuse problems in patient with acquired or cong... more Little is known about secondary impairments and overuse problems in patient with acquired or congenital upper limb deficiency. Our aim was to estimate the frequency of overuse problems in persons after unilateral upper limb deficiency and identify the factors relevant for development of these problems. Cross-sectional study conducted at the University Rehabilitation Institute in Ljubljana. In total, 65 persons after unilateral upper limb deficiency who had visited our subspecialist outpatient clinic during the 2011-2013 period (excluding those with other possible medical causes of overuse-type problems) were interviewed about the frequency, duration and severity of neck, elbow and shoulder pain and the presence of carpal tunnel syndrome and filled in the Orthotics and Prosthetics User Survey-Upper Extremity Functional Status questionnaire. The most frequent problem was carpal tunnel syndrome, followed by shoulder pain, neck pain and elbow pain. No statistically significant associati...
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, Jan 20, 2016
Adrenal venous sampling (AVS) is the only available method to distinguish bilateral from unilater... more Adrenal venous sampling (AVS) is the only available method to distinguish bilateral from unilateral primary aldosteronism (PA). AVS has several drawbacks, so it is reasonable to avoid this procedure when it would not affect clinical management. Our objective was to identify a clinical criterion that can reliably predict nonlateralized AVS as a surrogate for bilateral PA which is not treated surgically. A retrospective diagnostic cross-sectional study conducted at Slovenian national endocrine referral centre included 69 consecutive patients (mean age 56±8 years; 21 females) with PA that underwent AVS. PA was confirmed with the saline infusion test (SIT). AVS was performed sequentially during continuous ACTH infusion. Main outcome measures were variables associated with nonlateralized AVS to derive a clinical prediction rule. 67 patients (97%) had a successful AVS and were included in the statistical analysis. A total of 39 patients (58%) had nonlateralized AVS. The combined criterion...
Prispevek obravnava nekatera temeljna vprašanja, s katerimi se srečujejo raziskovalci na področju... more Prispevek obravnava nekatera temeljna vprašanja, s katerimi se srečujejo raziskovalci na področju strojnega učenja pri načrtovanju in statistični analizi eksperimentalnih študij. Po pregledu najpogostejših pomanjkljivosti in napak pri uporabi statističnih metod za medsebojno primerjavo klasifikacijskih algoritmov so podrobneje obravnavani relevantni statistični testi in eksperimentalni načrti. Kot primer nadgradnje teoretičnih osnov je prikazana uporaba Bonferronijevega popravka pri gradnji odločitvenih dreves, v zaključku pa je podanih nekaj dilem v zvezi z medsebojno primerjava napovedne uspešnosti regresijskih dreves.
To evaluate effectiveness of fall-risk-assessment-based fall prevention for stroke rehabilitation... more To evaluate effectiveness of fall-risk-assessment-based fall prevention for stroke rehabilitation inpatients. A consecutive series of 232 patients admitted for the first time to a subacute stroke-rehabilitation ward during 2010-2011 was studied in detail. The Assessment Sheet for Fall Prediction in Stroke Inpatients (ASFPSI by Nakagawa et al.) was used to assess fall-risk upon admission. Association of ASFPSI score and patient characteristics with actual falls was statistically tested. Yearly incidence of falls per 1000 hospital days (HD) was retrospectively audited for the 2006-2014 period to evaluate effectiveness of fall-risk reduction measures. The observed incidence of falls over the detailed-study-period was 3.0/1000 HD; 39% of the fallers fell during the first week after admission. ASFPSI score was not significantly associated with falls. Longer hospital stay, left body-side affected and non-extreme FIM score (55-101) were associated with higher odds of fall. Introduction of fall-risk reduction measures followed by compulsory fall-risk assessment lead to incidence of falls dropping from 7.1/1000 HD in 2006 to 2.8/1000 HD in 2011 and remaining at that level until 2014. The fall-risk-assessment-based measures appear to have led to decreasing falls risk among post-stroke rehabilitation inpatients classified as being at high risk of falls. The fall prevention programme as a whole was successful. Patients with non-extreme level of functional independence should receive enhanced fall prevention. Implications for Rehabilitation Recognising the fall risk upon the patient's admission is essential for preventing falls in rehabilitation wards. Assessing the fall risk is a team tasks and combines information from various sources. Assessing fall risk in stroke patients using the assessment sheet by Nakagawa et al. immediately upon admission systematically draws attention to the risk of falls in each individual patient.
Povzetek: Članek izhaja iz prenosa spoznanj Bandurove socialne kognitivne teorije v delovno praks... more Povzetek: Članek izhaja iz prenosa spoznanj Bandurove socialne kognitivne teorije v delovno prakso v podjetju.
Prispevek obravnava nekatera temeljna vprašanja, s katerimi se srečujejo raziskovalci na področju... more Prispevek obravnava nekatera temeljna vprašanja, s katerimi se srečujejo raziskovalci na področju strojnega učenja pri načrtovanju in statistični analizi eksperimentalnih študij. Po pregledu najpogostejših pomanjkljivosti in napak pri uporabi statističnih metod za medsebojno primerjavo klasifikacijskih algoritmov so podrobneje obravnavani relevantni statistični testi in eksperimentalni načrti. Kot primer nadgradnje teoretičnih osnov je prikazana uporaba Bonferronijevega popravka pri gradnji odločitvenih dreves, v zaključku pa je podanih nekaj dilem v zvezi z medsebojno primerjava napovedne uspešnosti regresijskih dreves.
Izvleček Podpora kliničnemu odločanju je ena od naprednejših, a premalo uporabljanih funkcij klin... more Izvleček Podpora kliničnemu odločanju je ena od naprednejših, a premalo uporabljanih funkcij kliničnih informacijskih sistemov. Teava pri uvajanju tovrstnih pripomočkov je predvsem potreba po uporabi računalniške opreme, ki pa mnogokrat ni dosegljiva na mestu dejanskega odločanja, npr. na vizitah, ob pogovorih s pacientom, ipd. V članku podajamo mono rešitev tega problema v obliki lupine za pomoč pri odločanju, ki deluje
Excel is the most widespread and the most powerful general-purpose spreadsheet software, but it i... more Excel is the most widespread and the most powerful general-purpose spreadsheet software, but it is not popular with statisticians. Nevertheless, as a natural means for organising, displaying and analysing large amounts of data, spreadsheets keep gaining importance in statistical education and practice. Aiming at improving such practice rather than fruitlessly and indiscriminately condemning it, the paper provides general considerations on the topic, pointers to the huge body of relevant literature and software, and several concrete examples of data visualisation in Excel in the sense of univariate, bivariate and multivariate distribution plotting. Original and improved Excel solutions for producing dot-density plots, dot plots, stem-and-leaf plots, windowgrams, coplots and parallel coordinates plots are presented, as well as for performing the Box-Cox transformation. Additionally, further possibilities opening with the forthcoming Excel 2007 version, use of various commercial and freeware add-ins, and integration of Excel with statistical software are discussed.
The study examined age and sex differences in social anxiety in different periods of adolescence ... more The study examined age and sex differences in social anxiety in different periods of adolescence and the relations between adolescents' social anxiety, self-consciousness and perception of self-incompetence. A new measure for assessing social anxi-ety in adolescence was constructed for this purpose. 325 subjects participated in the study: early (age 12), middle (age 16) and late (age 20) adolescents answered 36 test iterns of the newly developed Social Anxiety Scale for Adolescents (SASA) and were administered measures of self-consciousness (lmaginary Audience Scale, Self-Consciousness Scale) and perceived in-competence (Perceived lncompetence Scale, Perceived Sociallncompetence Scale). Factor analysis yielded two social anxiety factors: Apprehension and Fear ofNegative Evaluation decreased with adolescents' age and was more present in females than males, while Tension and Inhibition in Social Contacts did not differentiate either between the three age groups or between sexe...
A heat-map type of chart for depicting large number of cases and up to twenty-five categorical va... more A heat-map type of chart for depicting large number of cases and up to twenty-five categorical variables with spreadsheet software is presented. It is implemented in Microsoft ® Excel using standard formulas, sorting and simple VBA code. The motivating example depicts accuracy of automated assignment of MeSH ® descriptor headings to abstracts of medical articles. Within each abstract, predicted support for each heading is ranked, then for each heading actually assigned/non-assigned by human specialist (depicted by black/white cell), high/low support is depicted on nine-point two-colour scale. Thus, each case (abstract) is depicted by one row of a table and each variable (heading) with two adjacent columns. Rank-based classification accuracy measure is calculated for each case, and rows are sorted in increasing accuracy order downwards. Based on analogous measure, variables are sorted in increasing prediction accuracy order rightwards. Another biomedical dataset is presented with a similar chart. Different methods for predicting binary outcomes can be visualised, and the procedure is easily extended to polytomous variables. 6 ASSUME, the Association of Statistics Specialists Using Microsoft Excel, provides a starting point for an overview at
Prosthetics and orthotics international, Jan 28, 2015
Little is known about secondary impairments and overuse problems in patient with acquired or cong... more Little is known about secondary impairments and overuse problems in patient with acquired or congenital upper limb deficiency. Our aim was to estimate the frequency of overuse problems in persons after unilateral upper limb deficiency and identify the factors relevant for development of these problems. Cross-sectional study conducted at the University Rehabilitation Institute in Ljubljana. In total, 65 persons after unilateral upper limb deficiency who had visited our subspecialist outpatient clinic during the 2011-2013 period (excluding those with other possible medical causes of overuse-type problems) were interviewed about the frequency, duration and severity of neck, elbow and shoulder pain and the presence of carpal tunnel syndrome and filled in the Orthotics and Prosthetics User Survey-Upper Extremity Functional Status questionnaire. The most frequent problem was carpal tunnel syndrome, followed by shoulder pain, neck pain and elbow pain. No statistically significant associati...
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