Papers by Gaia Chiara Santi

BACKGROUND: Covid-19 pandemic is burning all over the world. National healthcare systems are faci... more BACKGROUND: Covid-19 pandemic is burning all over the world. National healthcare systems are facing the contagion with incredible strength, but concern regarding psychosocial and economic effects is critically growing. The PsyCovid Study assessed the influence of psychosocial variables on individual differences in the perceived impact of Covid-19 outbreak on health and economy in the Italian population.METHODS: Italian volunteers from different regions completed an online anonymous survey. Main outcomes were the perceived impact of Covid-19 outbreak on health and economy. A two-way MANOVA evaluated differences in main outcomes, with geographical area (northern, central and southern regions) and professional status (healthcare workers or not) as factors. We then tested the relationship linking psychosocial variables (i.e. perceived distress and social isolation, empathy and coping style) to the main outcomes through two different mediation models. RESULTS: 1163 responders completed t...
Journal of Health Psychology
Psychosocial variables are key factors influencing the delicate equilibrium of chronic patients d... more Psychosocial variables are key factors influencing the delicate equilibrium of chronic patients during crisis time. In this study, we explored distress, anxiety, depression, loneliness, coping strategies, and changes in life habits in 43 beta-thalassemia patients and 86 controls during Covid-19 pandemic. Patients showed higher anxiety levels and a predominant transcendent coping profile compared to controls. Patients significantly differed from controls in outdoor habits. Social isolation and habits changes in uncertain life-threaten situations as Covid-19 pandemic are particularly detrimental in fragile beta-thalassemia patients. Structured support interventions are needed to promote well-being in the Covid-19 era.

Journal of the International Neuropsychological Society
Objective: Late-onset amnestic mild cognitive impairment (aMCI) with long disease course and slow... more Objective: Late-onset amnestic mild cognitive impairment (aMCI) with long disease course and slow progression has been recently recognized as a possible phenotypical expression of a limbic-predominant neurodegenerative disorder. Basic emotion recognition ability crucially depending on temporo-limbic integrity is supposed to be impaired in this group of MCI subjects presenting a selective vulnerability of medio-temporal and limbic regions. However, no study specifically investigated this issue. Methods: Hereby, we enrolled 30 aMCI with a biomarker-based diagnosis of Alzheimer’s disease (i.e., aMCI-AD, n = 16) or a biomarker evidence of selective medio-temporal and limbic degeneration (aMCI-mTLD, n = 14). Ekman-60 Faces Test (Ek-60F) was administered to each subject, comparing the performance with that of 20 healthy controls (HCs). Results: aMCI-mTLD subjects showed significantly lower Ek-60F global scores compared to HC (p = 0.001), whose performance was comparable to aMCI-AD. Fear (...
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Papers by Gaia Chiara Santi