This study describes the potential geographical distribution of the most frequently sighted marin... more This study describes the potential geographical distribution of the most frequently sighted marine cetaceans in Venezuelan waters.Through GIS analysis,cetacean sightings were contrasted to topography and depth in order to generate distribution maps.Sixteen species(402 sighting records)were reported.Out of these,Balaenoptera edeni,Megaptera novaeangliae,Delphinus spp.,Sotalia guianensis,Stenella frontalis,Stenella longirostris and Tursiops truncatus were the most frequently sighted.Balaenoptera edeni and Tursiops truncatus might occupy the whole coast,including estuarine areas.The seasonal distribution of humpback whales is probably concentrated on insular coasts and shallow waters of the continental shelf.Delphinus spp.could be associated to high slope areas or coastal upwelling zones.Stenella frontalis is probably present in the western part of the Northeastern region,central coast and the parallel islands to the Venezuelan coast.Stenella longirostris could be in neritic and pelagi...
This paper studies the production of outpatient and inpatient care in public hospitals in Argenti... more This paper studies the production of outpatient and inpatient care in public hospitals in Argentina. This is a descriptive and correlational study that uses official data analyzed through multivariated statistical techniques and suggests three related facts. First, health care is not geographically homogeneous. Second, geographic per capita income per capita is important for outpatient care and age population pyramid in inpatient care. Third, the hypothesis stating that individuals with greater needs use less health care is confirmed. Thus, the inverse health care law rules in Argentina.
The Journal of Agriculture of the University of Puerto Rico, 1969
The soils of the area of Bella Union are deep, of high inherent fertility, and can hold and suppl... more The soils of the area of Bella Union are deep, of high inherent fertility, and can hold and supply sufficient amounts of water to a growing crop. They are mostly sandy clay loams and clay loams. Soil pH varies between 5.2 and 6.4. Some 38% of the soils have drainage problems mostly because of underlying impervious layers dominated by montmorillonitic clays. Irrigation and drainage are essential to guarantee high levels of crop production. Erosion can be a problem in some of the soils if they are not adequately protected. The use of open drains of suitable depth and spacing will help to maintain an optimum environment for the crops and, if well designed, can also help to minimize soil erosion.
The Journal of Agriculture of the University of Puerto Rico, 1969
Durante un reconocimiento de los suelos hecho recientemente en el Valle de Lajas, se observaron t... more Durante un reconocimiento de los suelos hecho recientemente en el Valle de Lajas, se observaron tumores o promontorios de los cuales mana una suspensión de suelo en agua. El área en cuestión está ubicada al noroeste de la laguna Guánica y en general se halla cubierta de una vegetación halofítica. Las baterías de pizómetros localizadas en el área indican una alta presión ascendente en toda esta área. Durante épocas de lluvia o cuando se está regando la caña en la vecindad del área afectada, la presión es tan fuerte que el agua asciende a través del suelo trayendo gran cantidad del mismo en suspensión. Los estudios sobre la composición mecánica del suelo de los tumores o promontorios y del suelo de sitios cercanos a los promontorios indican que la mayoría de las partículas en movimiento consiste de arcilla, con cantidades menores de limo y arena muy fina. Sin embargo, este movimiento está limitado, en su mayor grado, a las 48 pulgadas superficiales. Los niveles de materia orgánica y n...
The sharks of six and seven gill openings, that belong to the order Hexanchiformes, are very rare... more The sharks of six and seven gill openings, that belong to the order Hexanchiformes, are very rare in the commercial captures of tropical America; its species are typical inhabitants of cold boreal seas, and they rarely enter into warm waters. The capture of Hexanchus griseus, for the first time, in tropical waters of the American Pacific ocean, is presented in this record.
Journal of Clinical Laser Medicine & Surgery, 1995
... Pp. 263-265 In Vitro Release of Prostaglandin E2 after Helium-Neon Laser ... Each patient rec... more ... Pp. 263-265 In Vitro Release of Prostaglandin E2 after Helium-Neon Laser ... Each patient received 15 ap-plications of HeNe laser with an energy density of 8 J/cm2 each. We used the test for paired data: d = 5.25 ± 2.32 ng/mg of tissue/60 min (p < 0.01). ...
Journal of Clinical Laser Medicine & Surgery, 1996
This paper reports the effect of helium-neon laser radiation (power of 5 mW and 632.8 nm wave len... more This paper reports the effect of helium-neon laser radiation (power of 5 mW and 632.8 nm wave length) on the synthesis of PGE2 in vitro in synovial tissue of biopsy samples of knee joints in patients with chronic rheumatoid arthritis stages II or III. Twelve patients were studied. Each patient received 15 applications of He-Ne laser. Eleven points for He-Ne laser applications were selected in one of the affected knees. The energy density used was 8 J/cm2 per application point. The He-Ne laser therapy reduced the synthesis of PGE2. The analysis of the data revealed a statistically significant difference between the levels of the synthesis of PGE2 before treatment (17.69 +/- 2.65 ng mg-1 of dry tissue h-1) and after treatment (13.85 +/- 2.73 ng mg-1 of dry tissue h-1), with p < 0.01 comparing mean values. This was also accompanied by relief of pain (91.6%), and a favorable subjective report from the patient. We conclude that PGE2 is a quantifiable parameter that could explain what causes pain relief in patients with rheumatoid arthritis that are treated with He-Ne laser.
The equivalent of 0.12% lysine enrichment of white wheat flour resulted in significant enhancemen... more The equivalent of 0.12% lysine enrichment of white wheat flour resulted in significant enhancement of its protein value for the rapidly growing human infant, as demonstrated by increased rates of weight gain and nitrogen retention, stability of serum albumin, and elevation of the molar ratio of plasma lysine when the flour was the only source of protein in the diet. Isonitrogenous and isocaloric casein diets were used as controls. Enrichment to the 0.2% level resulted in suggestive further increases in the rates of weight gain and N retention, a further elevation in the molar ratio of plasma lysine and a reduction in that of plasma threonine. Enrichment to the 0.4% level resulted in a suggestive further increase in N retention alone and in further elevation of plasma lysine and reduction of plasma threonine. Enrichment of white wheat flour with lysine to the 0.12% and possibly the 0.2% level is recommended for those areas in which this cereal serves as the main source of protein in the diet, particularly that of infants and children. The improvement in biological value to be expected is enough to make the difference between dietary protein adequacy and deficiency to the many, without adverse effects on the few who might not profit by such enrichment. 10. CONTROL NUMBER II. PRICE OF DOCUMENT PN-AAC-571 12. DESCRIPTORS 13. PROJECT NUMBER Diets Protein supplements Flours Wheat 14. CONTRACT NUMBER Lysine rqn-jI'i R e, Nitrogen metabolism 1s. TYPE OF DOCUMENT
Four experimental aneurysms were treated by implantation of an endoprosthetic stent. The aneurysm... more Four experimental aneurysms were treated by implantation of an endoprosthetic stent. The aneurysms were surgically created by grafting a venous pouch on the carotid artery of mongrel dogs. Aneurysm patency was assessed angiographically. Under systemic heparinization and via a transfemoral approach, the stent measuring 20 mm in length and 5 mm in diameter, was implanted in the lumen of the parent artery at the level of the aneurysmal neck. Good angiographic results were obtained immediately following implantation, showing exclusion of the aneurysm from the circulation. Patency of the parent vessel was preserved in all the experimental aneurysms treated. In one case an angiogram performed 30 days later showed the same findings with excellent tolerance of the device. The technique of endovascular treatment of experimental aneurysms by stent implantation appears feasible and safe in vivo. Further investigations are still necessary before clinical applications.
Journal of thrombosis and haemostasis : JTH, Jan 17, 2017
Gas6 signals through the TAM (TYRO-3, AXL, MERTK) receptor family mediating platelet activation a... more Gas6 signals through the TAM (TYRO-3, AXL, MERTK) receptor family mediating platelet activation and thrombus formation via activation of the aggregate-stabilizing αIIb β3 integrin. Here we describe anti-thrombotic effects mediated by UNC2025, a small molecule MERTK tyrosine kinase inhibitor. MERTK phosphorylation and downstream signaling were assessed by immunoblot. Light transmission aggregometry, flow cytometry, and microfluidic analysis were used to evaluate the impact of MERTK inhibition on platelet activation and stability of aggregate formation in vitro. The effects of MERTK inhibition on arterial and venous thrombosis, platelet accumulation at microvascular injury sites, and tail bleeding times were determined using murine models. The effects of combined treatment with ADP/P2Y1&12 pathway antagonists and UNC2025 were also evaluated. Treatment with UNC2025 inhibited MERTK phosphorylation and downstream activation of AKT and SRC, decreased platelet activation, and protected ani...
This study proposes length relationship equations to determine total length of four species of sh... more This study proposes length relationship equations to determine total length of four species of sharks (Carcharhinus falciformis, Mustelus lunulatus, Sphyrna lewini and Carcharhinus limbatus) based on trunk lengths (TrL) and interdorsal lengths (IL) caught in Colombia and Central America Pacific Ocean. In Central American Pacific, data were
Journal of neuroradiology. Journal de neuroradiologie, 1997
Intracranial aneurysms occur frequently with the risk of major damage. Neurosurgery or endovascul... more Intracranial aneurysms occur frequently with the risk of major damage. Neurosurgery or endovascular techniques can be used for treatment. Current techniques are not well adapted for aneurysms with a wide implantation (or neck). The aim of this experimental work was to study a technique for treating aneurysms which can be used for wide neck aneurysms. A metal stent is implanted facing the neck of the aneurysm to allow occlusion. In the first part of the study, the stent was inserted alone. Ten aneurysms were created surgically in five dogs. The stents were positioned facing seven of the ten aneurysms. The stent led to immediate occlusion of the aneurysm in six of the cases. One aneurysm remained patent despite the correct position of the stent. One dog developed secondary thrombosis of the carotid. Three dogs have been followed for sixty days after insertion of the stent. Two aneurysms thrombosed and one was patent. Since these results were less than satisfactory, a second part of th...
This paper deals with the incorporation of bean flour (Phaseolus vulgaris, var. Tórtola) (BF) mad... more This paper deals with the incorporation of bean flour (Phaseolus vulgaris, var. Tórtola) (BF) made at laboratory scale in bread enrichment, by substituting 2, 4, 6, 8 and 10% wheat flour by bean flour. First, wheat and bean flours blends were prepared to study the farinological properties of these combinations. Then, breads containing bean flour in the above-mentioned proportions were made. At the 6, 8 and 10% levels, a deterioration in farinological properties of the blends, such as water absorption, developing time, weakening and W value were evident. Baking tests showed that no significant changes occurred with respect to water absorption, mixing time, weight and volume of breads, and color and texture of crumb in BF levels of 2, 4 and 6%. However, overall qualities of the breads were significantly impaired at the 8 and 10% levels.
Método: Se implementó encuestas a los destinatarios de los centros de salud de la provincia de Có... more Método: Se implementó encuestas a los destinatarios de los centros de salud de la provincia de Córdoba indagando acerca de aspectos sociodemográficos, tipo de asistencia sanitaria, motivo de consulta, accesibilidad y opinión general de la atención recibida. La información recabada fue procesada y analizada de acuerdo a la naturaleza de la variable y las comparaciones se efectuaron por ANOVA y para datos categorizados se utilizó coeficiente de contingencia (nivel de significación 0,05). Resultados: El acceso geográfico fue considerado aceptable por los encuestados al igual que el tiempo de espera y las condiciones edilicias. El desempeño profesional durante la atención, el vínculo establecido entre el profesional y el destinatario y el servicio brindado por el centro de salud fueron factores valorizados por los encuestados. Conclusión: El análisis de la satisfacción de los destinatarios de los centros de salud es importante para proporcionar información válida para generar respuestas oportunas y optimizar los recursos sanitarios.
This study describes the potential geographical distribution of the most frequently sighted marin... more This study describes the potential geographical distribution of the most frequently sighted marine cetaceans in Venezuelan waters.Through GIS analysis,cetacean sightings were contrasted to topography and depth in order to generate distribution maps.Sixteen species(402 sighting records)were reported.Out of these,Balaenoptera edeni,Megaptera novaeangliae,Delphinus spp.,Sotalia guianensis,Stenella frontalis,Stenella longirostris and Tursiops truncatus were the most frequently sighted.Balaenoptera edeni and Tursiops truncatus might occupy the whole coast,including estuarine areas.The seasonal distribution of humpback whales is probably concentrated on insular coasts and shallow waters of the continental shelf.Delphinus spp.could be associated to high slope areas or coastal upwelling zones.Stenella frontalis is probably present in the western part of the Northeastern region,central coast and the parallel islands to the Venezuelan coast.Stenella longirostris could be in neritic and pelagi...
This paper studies the production of outpatient and inpatient care in public hospitals in Argenti... more This paper studies the production of outpatient and inpatient care in public hospitals in Argentina. This is a descriptive and correlational study that uses official data analyzed through multivariated statistical techniques and suggests three related facts. First, health care is not geographically homogeneous. Second, geographic per capita income per capita is important for outpatient care and age population pyramid in inpatient care. Third, the hypothesis stating that individuals with greater needs use less health care is confirmed. Thus, the inverse health care law rules in Argentina.
The Journal of Agriculture of the University of Puerto Rico, 1969
The soils of the area of Bella Union are deep, of high inherent fertility, and can hold and suppl... more The soils of the area of Bella Union are deep, of high inherent fertility, and can hold and supply sufficient amounts of water to a growing crop. They are mostly sandy clay loams and clay loams. Soil pH varies between 5.2 and 6.4. Some 38% of the soils have drainage problems mostly because of underlying impervious layers dominated by montmorillonitic clays. Irrigation and drainage are essential to guarantee high levels of crop production. Erosion can be a problem in some of the soils if they are not adequately protected. The use of open drains of suitable depth and spacing will help to maintain an optimum environment for the crops and, if well designed, can also help to minimize soil erosion.
The Journal of Agriculture of the University of Puerto Rico, 1969
Durante un reconocimiento de los suelos hecho recientemente en el Valle de Lajas, se observaron t... more Durante un reconocimiento de los suelos hecho recientemente en el Valle de Lajas, se observaron tumores o promontorios de los cuales mana una suspensión de suelo en agua. El área en cuestión está ubicada al noroeste de la laguna Guánica y en general se halla cubierta de una vegetación halofítica. Las baterías de pizómetros localizadas en el área indican una alta presión ascendente en toda esta área. Durante épocas de lluvia o cuando se está regando la caña en la vecindad del área afectada, la presión es tan fuerte que el agua asciende a través del suelo trayendo gran cantidad del mismo en suspensión. Los estudios sobre la composición mecánica del suelo de los tumores o promontorios y del suelo de sitios cercanos a los promontorios indican que la mayoría de las partículas en movimiento consiste de arcilla, con cantidades menores de limo y arena muy fina. Sin embargo, este movimiento está limitado, en su mayor grado, a las 48 pulgadas superficiales. Los niveles de materia orgánica y n...
The sharks of six and seven gill openings, that belong to the order Hexanchiformes, are very rare... more The sharks of six and seven gill openings, that belong to the order Hexanchiformes, are very rare in the commercial captures of tropical America; its species are typical inhabitants of cold boreal seas, and they rarely enter into warm waters. The capture of Hexanchus griseus, for the first time, in tropical waters of the American Pacific ocean, is presented in this record.
Journal of Clinical Laser Medicine & Surgery, 1995
... Pp. 263-265 In Vitro Release of Prostaglandin E2 after Helium-Neon Laser ... Each patient rec... more ... Pp. 263-265 In Vitro Release of Prostaglandin E2 after Helium-Neon Laser ... Each patient received 15 ap-plications of HeNe laser with an energy density of 8 J/cm2 each. We used the test for paired data: d = 5.25 ± 2.32 ng/mg of tissue/60 min (p < 0.01). ...
Journal of Clinical Laser Medicine & Surgery, 1996
This paper reports the effect of helium-neon laser radiation (power of 5 mW and 632.8 nm wave len... more This paper reports the effect of helium-neon laser radiation (power of 5 mW and 632.8 nm wave length) on the synthesis of PGE2 in vitro in synovial tissue of biopsy samples of knee joints in patients with chronic rheumatoid arthritis stages II or III. Twelve patients were studied. Each patient received 15 applications of He-Ne laser. Eleven points for He-Ne laser applications were selected in one of the affected knees. The energy density used was 8 J/cm2 per application point. The He-Ne laser therapy reduced the synthesis of PGE2. The analysis of the data revealed a statistically significant difference between the levels of the synthesis of PGE2 before treatment (17.69 +/- 2.65 ng mg-1 of dry tissue h-1) and after treatment (13.85 +/- 2.73 ng mg-1 of dry tissue h-1), with p < 0.01 comparing mean values. This was also accompanied by relief of pain (91.6%), and a favorable subjective report from the patient. We conclude that PGE2 is a quantifiable parameter that could explain what causes pain relief in patients with rheumatoid arthritis that are treated with He-Ne laser.
The equivalent of 0.12% lysine enrichment of white wheat flour resulted in significant enhancemen... more The equivalent of 0.12% lysine enrichment of white wheat flour resulted in significant enhancement of its protein value for the rapidly growing human infant, as demonstrated by increased rates of weight gain and nitrogen retention, stability of serum albumin, and elevation of the molar ratio of plasma lysine when the flour was the only source of protein in the diet. Isonitrogenous and isocaloric casein diets were used as controls. Enrichment to the 0.2% level resulted in suggestive further increases in the rates of weight gain and N retention, a further elevation in the molar ratio of plasma lysine and a reduction in that of plasma threonine. Enrichment to the 0.4% level resulted in a suggestive further increase in N retention alone and in further elevation of plasma lysine and reduction of plasma threonine. Enrichment of white wheat flour with lysine to the 0.12% and possibly the 0.2% level is recommended for those areas in which this cereal serves as the main source of protein in the diet, particularly that of infants and children. The improvement in biological value to be expected is enough to make the difference between dietary protein adequacy and deficiency to the many, without adverse effects on the few who might not profit by such enrichment. 10. CONTROL NUMBER II. PRICE OF DOCUMENT PN-AAC-571 12. DESCRIPTORS 13. PROJECT NUMBER Diets Protein supplements Flours Wheat 14. CONTRACT NUMBER Lysine rqn-jI'i R e, Nitrogen metabolism 1s. TYPE OF DOCUMENT
Four experimental aneurysms were treated by implantation of an endoprosthetic stent. The aneurysm... more Four experimental aneurysms were treated by implantation of an endoprosthetic stent. The aneurysms were surgically created by grafting a venous pouch on the carotid artery of mongrel dogs. Aneurysm patency was assessed angiographically. Under systemic heparinization and via a transfemoral approach, the stent measuring 20 mm in length and 5 mm in diameter, was implanted in the lumen of the parent artery at the level of the aneurysmal neck. Good angiographic results were obtained immediately following implantation, showing exclusion of the aneurysm from the circulation. Patency of the parent vessel was preserved in all the experimental aneurysms treated. In one case an angiogram performed 30 days later showed the same findings with excellent tolerance of the device. The technique of endovascular treatment of experimental aneurysms by stent implantation appears feasible and safe in vivo. Further investigations are still necessary before clinical applications.
Journal of thrombosis and haemostasis : JTH, Jan 17, 2017
Gas6 signals through the TAM (TYRO-3, AXL, MERTK) receptor family mediating platelet activation a... more Gas6 signals through the TAM (TYRO-3, AXL, MERTK) receptor family mediating platelet activation and thrombus formation via activation of the aggregate-stabilizing αIIb β3 integrin. Here we describe anti-thrombotic effects mediated by UNC2025, a small molecule MERTK tyrosine kinase inhibitor. MERTK phosphorylation and downstream signaling were assessed by immunoblot. Light transmission aggregometry, flow cytometry, and microfluidic analysis were used to evaluate the impact of MERTK inhibition on platelet activation and stability of aggregate formation in vitro. The effects of MERTK inhibition on arterial and venous thrombosis, platelet accumulation at microvascular injury sites, and tail bleeding times were determined using murine models. The effects of combined treatment with ADP/P2Y1&12 pathway antagonists and UNC2025 were also evaluated. Treatment with UNC2025 inhibited MERTK phosphorylation and downstream activation of AKT and SRC, decreased platelet activation, and protected ani...
This study proposes length relationship equations to determine total length of four species of sh... more This study proposes length relationship equations to determine total length of four species of sharks (Carcharhinus falciformis, Mustelus lunulatus, Sphyrna lewini and Carcharhinus limbatus) based on trunk lengths (TrL) and interdorsal lengths (IL) caught in Colombia and Central America Pacific Ocean. In Central American Pacific, data were
Journal of neuroradiology. Journal de neuroradiologie, 1997
Intracranial aneurysms occur frequently with the risk of major damage. Neurosurgery or endovascul... more Intracranial aneurysms occur frequently with the risk of major damage. Neurosurgery or endovascular techniques can be used for treatment. Current techniques are not well adapted for aneurysms with a wide implantation (or neck). The aim of this experimental work was to study a technique for treating aneurysms which can be used for wide neck aneurysms. A metal stent is implanted facing the neck of the aneurysm to allow occlusion. In the first part of the study, the stent was inserted alone. Ten aneurysms were created surgically in five dogs. The stents were positioned facing seven of the ten aneurysms. The stent led to immediate occlusion of the aneurysm in six of the cases. One aneurysm remained patent despite the correct position of the stent. One dog developed secondary thrombosis of the carotid. Three dogs have been followed for sixty days after insertion of the stent. Two aneurysms thrombosed and one was patent. Since these results were less than satisfactory, a second part of th...
This paper deals with the incorporation of bean flour (Phaseolus vulgaris, var. Tórtola) (BF) mad... more This paper deals with the incorporation of bean flour (Phaseolus vulgaris, var. Tórtola) (BF) made at laboratory scale in bread enrichment, by substituting 2, 4, 6, 8 and 10% wheat flour by bean flour. First, wheat and bean flours blends were prepared to study the farinological properties of these combinations. Then, breads containing bean flour in the above-mentioned proportions were made. At the 6, 8 and 10% levels, a deterioration in farinological properties of the blends, such as water absorption, developing time, weakening and W value were evident. Baking tests showed that no significant changes occurred with respect to water absorption, mixing time, weight and volume of breads, and color and texture of crumb in BF levels of 2, 4 and 6%. However, overall qualities of the breads were significantly impaired at the 8 and 10% levels.
Método: Se implementó encuestas a los destinatarios de los centros de salud de la provincia de Có... more Método: Se implementó encuestas a los destinatarios de los centros de salud de la provincia de Córdoba indagando acerca de aspectos sociodemográficos, tipo de asistencia sanitaria, motivo de consulta, accesibilidad y opinión general de la atención recibida. La información recabada fue procesada y analizada de acuerdo a la naturaleza de la variable y las comparaciones se efectuaron por ANOVA y para datos categorizados se utilizó coeficiente de contingencia (nivel de significación 0,05). Resultados: El acceso geográfico fue considerado aceptable por los encuestados al igual que el tiempo de espera y las condiciones edilicias. El desempeño profesional durante la atención, el vínculo establecido entre el profesional y el destinatario y el servicio brindado por el centro de salud fueron factores valorizados por los encuestados. Conclusión: El análisis de la satisfacción de los destinatarios de los centros de salud es importante para proporcionar información válida para generar respuestas oportunas y optimizar los recursos sanitarios.
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