Papers by Felix Baerlocher
Il Farmaco, 1999
N-Isoxazolyl-2-iodobenzamides 3 and 9, with a benodanil-like structure, were synthesized by reflu... more N-Isoxazolyl-2-iodobenzamides 3 and 9, with a benodanil-like structure, were synthesized by refluxing in acetic acid the corresponding benzotriazinones 2 and 8 with potassium iodide for 1 h with the aim to ascertain if they were active as fungicides against Phytophthora citricola Saw., Botrytis cinerea Pers., Rhizoctonia sp. and Alternaria sp. Among the tested iodo derivatives, compounds 3b and 9a possess interesting activities against the aforesaid fungal strains in several cases similar to that of benodanil I taken as reference drug.
Journal of Vascular and Interventional Radiology, Jul 1, 2020
The concept of aerosol-generating procedures (AGPs) or aerosol-generating medical procedures (AGM... more The concept of aerosol-generating procedures (AGPs) or aerosol-generating medical procedures (AGMPs) was developed by the World Health Organization (WHO) and the US Centers for Disease Control and Prevention (CDC) in the wake of the outbreaks of Ebola (1). An AGP is defined as any medical procedure that can induce the production of aerosols of various sizes, including small (<5 μm) particles (2). The implication is that aerosols are associated with a greater risk of transmission to others, including health care workers (HCWs). The original list of AGPs compiled by the WHO included such terms as intubation, extubation, manual ventilation, open suctioning, cardiopulmonary resuscitation, bronchoscopy, surgery, and postmortem procedures involving highspeed devices, for example, in some dental procedures (eg, drilling); noninvasive ventilation such as bi-level positive airway pressure (BiPAP) and continuous positive airway pressure (CPAP) ventilation, high-frequency oscillating ventilation (HFOV), and induction of sputum (3). A subsequent meta-analysis sought to determine the published evidence for transmission of acute respiratory infections to HCWs from patients undergoing AGPs and comparing the incidence to that of the risk from patients not undergoing AGPs (4). A total of 5 case-control and 5 retrospective cohort studies were included which evaluated transmission of severe acute respiratory syndrome to HCWs. A limited number of procedures were evaluated,
ChemInform, Jun 9, 2009
Synthesis, Structure, and Antifungal Activity of Dihydropyridones Containing Boronate Esters.-A s... more Synthesis, Structure, and Antifungal Activity of Dihydropyridones Containing Boronate Esters.-A series of novel 2,3-dihydro-4-pyridones containing boronate esters (III) is synthesized using the aza Diels-Alder reaction of Danishefsky's diene with imines derived from formylphenylboronic acids. Compounds (IIa) and (IIb) show moderate antifungal activity.-(APPOH, F. E.;
ChemInform, May 23, 2010
ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was e... more ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Heteroatom Chemistry, 2009
ABSTRACT
Canadian Journal of Chemistry, 2001
Addition of 3-H2NC6H4Bpin (pin = 1,2-O2C2Me4) to a series of aldehydes and 4-(4,4,5,5-tetramethyl... more Addition of 3-H2NC6H4Bpin (pin = 1,2-O2C2Me4) to a series of aldehydes and 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)acetophenone afforded the corresponding benzylideneamines in moderate to high yields. Hydroboration of these imines with catecholborane (HBcat, cat = 1,2-O2C6H4) at room temperature gives, upon aqueous workup, the corresponding borylamines. An X-ray diffraction study was carried out on imine 1h derived from 9-anthraldehyde and 3-H2NC6H4Bpin. Crystals of1h were triclinic, a = 9.6793(4) Å, b = 10.7397(4) Å, c = 11.5353(4) Å, α = 105.1890(10)o, β = 97.3030(10)o, γ = 102.1480(10)o, Z = 2 with space group P[Formula: see text] and crystals of N-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-4-methoxybenzylamine 2c were orthorhombic, a = 8.6612(4) Å, b = 10.3794(4) Å, c = 20.6033(9) Å, Z = 4 with space group P212121. Amines have been tested for their antifungal properties against Aspergillus niger and Aspergillus flavus.Key words: benzylamines, boronate esters, aminoboron, hydroboration, antifungal.
Chemistry & Biodiversity, Nov 1, 2008
Addition of thiosemicarbazide, 4-allylthiosemicarbazide, and 4-phenylthiosemicarbazide to (formyl... more Addition of thiosemicarbazide, 4-allylthiosemicarbazide, and 4-phenylthiosemicarbazide to (formylphenyl)boronic acids affords a series of thiosemicarbazones containing boronic acids. Addition of 2-formylphenylboronic acid to the thiosemicarbazides gave the corresponding cyclic 2,3,1-benzodiazaborines. All new compounds have been investigated for potential antifungal activity.
Transition Metal Chemistry, Sep 10, 2015
The reaction of [PdCl2(η2-coe)]2 (coe = cis-cyclooctene) with nine lipophilic iminopyridine ligan... more The reaction of [PdCl2(η2-coe)]2 (coe = cis-cyclooctene) with nine lipophilic iminopyridine ligands (NN′, 1a–i) afforded the corresponding metal complexes cis-[PdCl2(NN′)] (2a–i) with concomitant loss of the labile coe ligands. All iminopyridine complexes were characterized by physicochemical and spectroscopic methods. The molecular structures of two complexes, 2a and 2b, were determined by single crystal X-ray diffraction studies. All complexes were tested for their potential antifungal and antibacterial activities.
Journal of Molecular Structure, Sep 1, 2011
A family of arylspiroborates has been prepared by the addition of 4-nitrocatechol, boric acid and... more A family of arylspiroborates has been prepared by the addition of 4-nitrocatechol, boric acid and either an alkali metal hydroxide or an ammonium hydroxide. All compounds were characterized fully using multinuclear NMR spectroscopy, FT-IR spectroscopy and by elemental analyses. A single crystal X-ray diffraction was carried out on triethylmethylammonium 4-nitro[1,2-benzenediolato(2-)-O,O′]borate (5). All new compounds were tested for potential fungicidal activity.
Canadian Journal of Chemistry, Oct 1, 2018
The addition of 4-ethyl-3-thiosemicarbazide to benzaldehyde and boronic acid-containing derivativ... more The addition of 4-ethyl-3-thiosemicarbazide to benzaldehyde and boronic acid-containing derivatives afforded the corresponding thiosemicarbazones (1-3) or benzodiazaborines (4-6) depending on the position of the boronic acid within the ring. All compounds have been characterized fully including an X-ray diffraction study of the methoxy-containing benzodiazaborine 6. Attempts to coordinate thiosemicarbazones 2 and 3 to palladium(II) acetate were unsuccessful, however, addition of the non-boroncontaining derivative 1 to palladium afforded complex 7 whose molecular structure was determined by an X-ray diffraction study. The initial bioactivities of compounds 1-7 were examined against two fungi, Aspergillus niger and Saccharomyces cerevisiae, and two bacteria, Bacillus cereus and Pseudomonas aeruginosa.
Australian Journal of Chemistry, 2015
S e v e r a l new hexa-coordinated ruthenium(1TT) Complexes o f the type [RuX2(EPh3)2(LLt)], (X =... more S e v e r a l new hexa-coordinated ruthenium(1TT) Complexes o f the type [RuX2(EPh3)2(LLt)], (X = C 1 o r Br; E = P or As) [where L L t = rnorpholinedithiocarhamate (Morphdtc), piperidinedithiocarhamate (Pipdtc) and piperazinedithlocarhamate (Pzdtcl have been synthesised. In all these complexes the heterocyclic dithiocarbamates behave as a uninegative btdentate (SS) chelating ligand. It has been observed that the incoming ligand replaces a halide, a tertiarv phosphine/arslne and methanol from the starting complexes. All the complexes have been charactertsed on the hasis o f analytical and spectroscopic data. T h e n e w complexes s h o w e d a reasonable amount o f a n t i f u n g a l activities.
Advanced Functional Materials, 2018
Gravity and magnetism are implemented to change the morphology of zinc oxide nanorod sensors duri... more Gravity and magnetism are implemented to change the morphology of zinc oxide nanorod sensors during synthesis. The effects of gravity and magnetism can translate into future application of these nanorods through cost-effective, environmentally friendly, and easy-to-use biosensor technology with the quickest available sensing. The sensors can pave the way toward detection of both bacteria and fungi present on the surface with high sensitivity. This ability to sense microorganisms in a "non-solution-based" environment represents a key step forward in the fields of health and food safety, as well as solid-state nanomaterial biotechnology applications. Hundreds of thousands of people are affected each year by accidental contamination and current protocols are far from preventative. The results of the magnetic field studies when compared with previous results show that the following factors affect the outcome of applying magnetic field during the growth of nanorods on their morphology: the direction of growth with respect to gravity, the method of seeding, and the substrate.
Transition Metal Chemistry, 2015
The reaction of Cu(II) sulfate or Pd(II) acetate with four salicylaldimines derived from 5-bromos... more The reaction of Cu(II) sulfate or Pd(II) acetate with four salicylaldimines derived from 5-bromosalicylaldehyde and long-chain aliphatic primary amines afforded the corresponding metal complexes 2a-d and 3a-d, respectively. All complexes were characterized by physicochemical and spectroscopic methods. The molecular structure of 2b was determined by a single-crystal X-ray diffraction study. All complexes were tested for their potential antifungal and antibacterial activities.
Transition Metal Chemistry, 2017
Six Schiff base compounds have been prepared from the condensation of o-vanillin, 2,3-dihydroxybe... more Six Schiff base compounds have been prepared from the condensation of o-vanillin, 2,3-dihydroxybenzaldehyde and 2,3,4-trihydroxybenzaldehyde with 4aminosalicylic acid (4-ASA) and 5-aminosalicylic acid (5-ASA). Addition of these Schiff bases to [Pd(OAc)2] afforded the corresponding bis(salicylaldiminato)palladium(II) complexes in moderate to excellent yields. All new palladium complexes have been characterized fully using standard spectroscopic methods, elemental analyses and a single crystal X-ray diffraction study in the case of 2e, the palladium complex containing Schiff base ligands derived from 5-ASA and 2,3-dihydroxybenzaldehyde. All derivatives of 5-ASA were examined for potential antimicrobial activities against two species of fungi, Aspergillus niger and Saccharomyces cerevisiae, as well as two species of bacteria, Bacillus cereus (Gram-positive) and Pseudomonas aeruginosa
EU Gas Security Architecture, 2016
This chapter starts by tracing the idea of the unification of the European energy markets from th... more This chapter starts by tracing the idea of the unification of the European energy markets from the times of the European Coal and Steal Community in 1950s and then explains why European countries subsequently became heavily dependent on oil supplies from the Middle East. It is then argued that oil disruptions of the 1970s, new gas discoveries and the “steel for gas” deals with the Soviet Union were decisive for the evolution of the current gas infrastructure. The parts of the chapter that trace the developments of the EU gas markets after the Soviet breakup and Eastern enlargement show that the 2006 and 2009 gas interruptions to Ukraine have partially motivated new EU gas legislation, which Russia perceived as threatening to her economic interests.
Fundamental and Applied Limnology / Archiv für Hydrobiologie
Internationale Revue der gesamten Hydrobiologie und Hydrographie
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Papers by Felix Baerlocher