The mitochondrion is a tiny organelle that is the power supplier of the cell and vital to the fun... more The mitochondrion is a tiny organelle that is the power supplier of the cell and vital to the functioning of the body organs. Additionally it contains a small circular genome of about 16 kb, present in many copies which makes the mitochondrial DNA more viable than nuclear DNA. Mitochondrial DNA is also maternally inherited and thus provides a direct link to maternal relatives. These two properties are of particular use for forensic samples, which only contain limited or degraded amounts of DNA, and for historical samples (ancient DNA). This thesis presents work on the mitochondrial DNA in the hypervariable regions (HV) I and II, in both contemporary and historical samples. Forensic genetics makes use of mitochondrial DNA analysis in court as circumstantial evidence, and population databases are used for the calculation of evidence value. Population samples (299) across Sweden have been analysed in order to enrich the EDNAP mtDNA database (EMPOP) (paper I). The application of mitochondrial DNA analysis allowed for analysis of historical skeletal remains: Copernicus, 1473-1543 (paper II), Karin Goring, 1888-1931 (paper III) and Medieval bones, 880-1000 AD, from a mass grave found in Sigtuna, Sweden (paper IV). The thesis also includes analyses of bones and teeth from the shipwrecked crew of the Vasa warship, 1628, samples from the Vasa museum, Stockholm, Sweden (paper V). Overall, the varying age of the samples and the different conservation environments (soil and water) accounted for variations in quality, but still allowed for successful DNA analysis.
In 2014 the Friends of the Vasa Museum carried out live firing trials of an accurate replica of t... more In 2014 the Friends of the Vasa Museum carried out live firing trials of an accurate replica of the main ordnance system used on the Swedish warship Vasa, sunk in 1628. The purpose of the trials was to assess the ballistic performance of this type of lightweight 24-pounder bronze gun, its effect on ship structure and the ergonomic aspects of servicing the piece. This article reports on the effect aspects of the trials, with specific attention to the affect that the details of ship structure have on the creation and dispersion of splinters inside the ship. Introduction The conventional impression of the nature of naval warfare in the age of sail and broadside gunnery is one of chaos, noise and horrific carnage. Men cut down by cannonballs, clouds of deadly flying splinters and torrents of blood in the scuppers have been staples of naval fiction from the novels of Tobias Smollett to films such as Master and Commander. While there were no doubt moments like this, surviving after-action...
Sintok (Cinnamomum sintoc Blume) merupakan salah satu tanaman obat yang tersebar di Kalimantan, S... more Sintok (Cinnamomum sintoc Blume) merupakan salah satu tanaman obat yang tersebar di Kalimantan, Sumatera dan Jawa. Secara ilmu kemotaksonomi diduga sintok memiliki aktivitas antioksidan. Penelitian ini bertujuan untuk mengetahui aktivitas antioksidan dari ekstrak dan fraksi aktif kulit batang Cinnamomum sintoc Blume menggunakan metode DPPH (1,1-diphenyl-2-pikril-hidrazil) dan vitamin C sebagai pembanding. Kulit batang Cinnamomum sintoc Blume diekstraksi dengan cara maserasi bertingkat meggunakan pelarut n-heksan, etil asetat dan metanol. Ekstrak metanol menunjukkan aktivitas antioksidan tertinggi dengan nilai IC 50 12,037 μg/ml (Antioxidant Activity Index (AAI): 3,32). Ekstrak metanol difraksinasi lebih lanjut, sehingga didapatkan fraksi A dengan nilai IC 50 6,202 μg/ml (AAI: 6,5).
The 10th International Symposium on Boat and Ship Archaeology was held in Roskilde, Denmark in 20... more The 10th International Symposium on Boat and Ship Archaeology was held in Roskilde, Denmark in 2003. The theme of the meeting was" Connected by the Sea", and was designed to emphasise the role of the sea, seafaring and watercraft as bridges rather than ...
Hocker notes that after staring at these words for quite some time, he has no strong intuitive pr... more Hocker notes that after staring at these words for quite some time, he has no strong intuitive preference for the texts referring to ship architecture rather than house architecture. It should be worthwhile for experts in Mycenaean palatial architecture to examine these texts anew.
The mitochondrion is a tiny organelle that is the power supplier of the cell and vital to the fun... more The mitochondrion is a tiny organelle that is the power supplier of the cell and vital to the functioning of the body organs. Additionally it contains a small circular genome of about 16 kb, present in many copies which makes the mitochondrial DNA more viable than nuclear DNA. Mitochondrial DNA is also maternally inherited and thus provides a direct link to maternal relatives. These two properties are of particular use for forensic samples, which only contain limited or degraded amounts of DNA, and for historical samples (ancient DNA). This thesis presents work on the mitochondrial DNA in the hypervariable regions (HV) I and II, in both contemporary and historical samples. Forensic genetics makes use of mitochondrial DNA analysis in court as circumstantial evidence, and population databases are used for the calculation of evidence value. Population samples (299) across Sweden have been analysed in order to enrich the EDNAP mtDNA database (EMPOP) (paper I). The application of mitochondrial DNA analysis allowed for analysis of historical skeletal remains: Copernicus, 1473-1543 (paper II), Karin Goring, 1888-1931 (paper III) and Medieval bones, 880-1000 AD, from a mass grave found in Sigtuna, Sweden (paper IV). The thesis also includes analyses of bones and teeth from the shipwrecked crew of the Vasa warship, 1628, samples from the Vasa museum, Stockholm, Sweden (paper V). Overall, the varying age of the samples and the different conservation environments (soil and water) accounted for variations in quality, but still allowed for successful DNA analysis.
In 2014 the Friends of the Vasa Museum carried out live firing trials of an accurate replica of t... more In 2014 the Friends of the Vasa Museum carried out live firing trials of an accurate replica of the main ordnance system used on the Swedish warship Vasa, sunk in 1628. The purpose of the trials was to assess the ballistic performance of this type of lightweight 24-pounder bronze gun, its effect on ship structure and the ergonomic aspects of servicing the piece. This article reports on the effect aspects of the trials, with specific attention to the affect that the details of ship structure have on the creation and dispersion of splinters inside the ship. Introduction The conventional impression of the nature of naval warfare in the age of sail and broadside gunnery is one of chaos, noise and horrific carnage. Men cut down by cannonballs, clouds of deadly flying splinters and torrents of blood in the scuppers have been staples of naval fiction from the novels of Tobias Smollett to films such as Master and Commander. While there were no doubt moments like this, surviving after-action...
Sintok (Cinnamomum sintoc Blume) merupakan salah satu tanaman obat yang tersebar di Kalimantan, S... more Sintok (Cinnamomum sintoc Blume) merupakan salah satu tanaman obat yang tersebar di Kalimantan, Sumatera dan Jawa. Secara ilmu kemotaksonomi diduga sintok memiliki aktivitas antioksidan. Penelitian ini bertujuan untuk mengetahui aktivitas antioksidan dari ekstrak dan fraksi aktif kulit batang Cinnamomum sintoc Blume menggunakan metode DPPH (1,1-diphenyl-2-pikril-hidrazil) dan vitamin C sebagai pembanding. Kulit batang Cinnamomum sintoc Blume diekstraksi dengan cara maserasi bertingkat meggunakan pelarut n-heksan, etil asetat dan metanol. Ekstrak metanol menunjukkan aktivitas antioksidan tertinggi dengan nilai IC 50 12,037 μg/ml (Antioxidant Activity Index (AAI): 3,32). Ekstrak metanol difraksinasi lebih lanjut, sehingga didapatkan fraksi A dengan nilai IC 50 6,202 μg/ml (AAI: 6,5).
The 10th International Symposium on Boat and Ship Archaeology was held in Roskilde, Denmark in 20... more The 10th International Symposium on Boat and Ship Archaeology was held in Roskilde, Denmark in 2003. The theme of the meeting was" Connected by the Sea", and was designed to emphasise the role of the sea, seafaring and watercraft as bridges rather than ...
Hocker notes that after staring at these words for quite some time, he has no strong intuitive pr... more Hocker notes that after staring at these words for quite some time, he has no strong intuitive preference for the texts referring to ship architecture rather than house architecture. It should be worthwhile for experts in Mycenaean palatial architecture to examine these texts anew.
Uploads
Papers by Fred Hocker