Papers by Evelien Schepper
Osteoarthritis and Cartilage, 2011
Objective: To explore the associations between spinal morning stiffness and lumbar disc degenerat... more Objective: To explore the associations between spinal morning stiffness and lumbar disc degeneration (LDD). Design: Data from a cross-sectional general population-based study (Rotterdam Study-I) were used. Intervertebral disc spaces and osteophytes of people aged !55 years were scored on lumbar lateral radiographs (L1-2 through L5-S1 was scored). Logistic regression analysis was used to explore associations between spinal morning stiffness and two definitions of LDD (i.e., 'narrowing' and 'osteophytes'). Spinal morning stiffness combined with low back pain and its association with LDD was also analyzed. Similar analyses were performed for knee and hip pain, morning stiffness in the legs, and radiographic knee and hip osteoarthritis (OA) in order to compare these associations with those of LDD. All analyses were adjusted for age, gender, and body mass index (BMI). Results: Lumbar lateral radiographs were scored for 2,819 participants. Both definitions of LDD were associated with spinal morning stiffness: adjusted odds ratio (aOR) 1.3; 95% confidence interval (CI): 1.1e1.6 for 'osteophytes' and aOR 1.8; 95% CI: 1.4e2.2 for 'narrowing'. Both the odds ratios increased when spinal morning stiffness was combined with low back pain: aOR 1.5; 95% CI: 1.1e2.0 for 'osteophytes' and aOR 2.5; 95% CI: 1.9e3.4 for 'narrowing'. When morning stiffness in the legs was combined with knee or hip pain, the associations with radiographic knee or hip OA were: aOR 3.0; 95% CI: 2.1e4.1 for knee OA and aOR 3.1; 95% CI: 1.9e5.0 for hip OA. Conclusions: Reported spinal morning stiffness is associated with LDD. The associations increased when we combined spinal morning stiffness with low back pain. The magnitude of the association for the definition 'narrowing' is similar to the association between morning stiffness in the legs and knee or hip OA.
Osteoarthritis and Cartilage, 2012
Osteoarthritis and Cartilage, 2010
Purpose A possible cause of hip pain is the presence of radiating pain from the higher lumbar spi... more Purpose A possible cause of hip pain is the presence of radiating pain from the higher lumbar spine. Identification of factors associated with hip pain arising from the lumbar spine would aid the physician. The first step in identifying possible factors is to look at the association between hip pain and osteoarthritis of the lumbar spine.
Osteoarthritis and Cartilage, 2012
Objective: To explore the associations between spinal morning stiffness and lumbar disc degenerat... more Objective: To explore the associations between spinal morning stiffness and lumbar disc degeneration (LDD). Design: Data from a cross-sectional general population-based study (Rotterdam Study-I) were used. Intervertebral disc spaces and osteophytes of people aged !55 years were scored on lumbar lateral radiographs (L1-2 through L5-S1 was scored). Logistic regression analysis was used to explore associations between spinal morning stiffness and two definitions of LDD (i.e., 'narrowing' and 'osteophytes'). Spinal morning stiffness combined with low back pain and its association with LDD was also analyzed. Similar analyses were performed for knee and hip pain, morning stiffness in the legs, and radiographic knee and hip osteoarthritis (OA) in order to compare these associations with those of LDD. All analyses were adjusted for age, gender, and body mass index (BMI). Results: Lumbar lateral radiographs were scored for 2,819 participants. Both definitions of LDD were associated with spinal morning stiffness: adjusted odds ratio (aOR) 1.3; 95% confidence interval (CI): 1.1e1.6 for 'osteophytes' and aOR 1.8; 95% CI: 1.4e2.2 for 'narrowing'. Both the odds ratios increased when spinal morning stiffness was combined with low back pain: aOR 1.5; 95% CI: 1.1e2.0 for 'osteophytes' and aOR 2.5; 95% CI: 1.9e3.4 for 'narrowing'. When morning stiffness in the legs was combined with knee or hip pain, the associations with radiographic knee or hip OA were: aOR 3.0; 95% CI: 2.1e4.1 for knee OA and aOR 3.1; 95% CI: 1.9e5.0 for hip OA. Conclusions: Reported spinal morning stiffness is associated with LDD. The associations increased when we combined spinal morning stiffness with low back pain. The magnitude of the association for the definition 'narrowing' is similar to the association between morning stiffness in the legs and knee or hip OA.
Bone, 2013
10 11 a b s t r a c t a r t i c l e i n f o 12 Lumbar disc degeneration 24 Osteoporotic fractures... more 10 11 a b s t r a c t a r t i c l e i n f o 12 Lumbar disc degeneration 24 Osteoporotic fractures 25 Bone Mineral Density 26 Disc space narrowing 27 Vertebral fractures 28
European Spine Journal, 2013
Purpose A possible cause of hip pain is the presence of radiating pain from the higher lumbar spi... more Purpose A possible cause of hip pain is the presence of radiating pain from the higher lumbar spine. Identification of factors associated with hip pain arising from the lumbar spine would aid the physician. The first step in identifying possible factors is to look at the association between hip pain and osteoarthritis of the lumbar spine.
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Papers by Evelien Schepper