Papers by Eduardo Hermosilla Villar
Pathology, research and practice, 2018
Lung cancer, particularly non-small cell lung cancer (NSCLC) subtype, is the leading cause of can... more Lung cancer, particularly non-small cell lung cancer (NSCLC) subtype, is the leading cause of cancer-related death related worldwide. Numerous gene polymorphisms in DNA repair, folate and glutathione pathways have been associated with susceptibility of NSCLC. We conducted this study to evaluate the effects of ERCC1, ERCC2, ERCC5, XRCC1, XRCC3, MTHFR, MTR, MTHFD1, SLC19A1 and GSTP1 gene polymorphisms on risk of NSCLC. No association between these gene polymorphisms and susceptibility of NSCLC were found in our patients, suggesting that genetic variations in genes involved in DNA repair, folate and glutathione metabolism pathways may not influence the risk of NSCLC.
Surgical oncology, 2017
Surgery is the standard treatment for early-stage NSCLC, and platinum-based chemotherapy remains ... more Surgery is the standard treatment for early-stage NSCLC, and platinum-based chemotherapy remains as the treatment of choice for advanced-stage NSCLC patients with naïve EGFR status. However, overall 5-years relative survival rates are low. Interleukins (ILs) are crucial for processes associated with tumor development. In NSCLC, IL1B, IL6, IL12A, IL13 and IL16 gene polymorphisms may contribute to individual variation in terms of patient survival. The purpose of this study was to evaluate the association between IL gene polymorphisms and survival in NSCLC patients. A prospective cohorts study was performed, including 170 NSCLC patients (114 Stage IIIB-IV, 56 Stage I-IIIA). IL1B (C > T; rs1143634), IL1B (C > T; rs12621220), IL1B (C > G; rs1143623), IL1B (A > G; rs16944), IL1B (C > T; rs1143627), IL6 (C > G; rs1800795), IL12A (C > T; rs662959), IL13 (A > C; rs1881457) and IL16 (G > T; rs7170924) gene polymorphisms were analyzed by PCR Real-Time. Patients with ...
... El presente documento describe el trabajo hecho durante la realización del Proyecto Final de ... more ... El presente documento describe el trabajo hecho durante la realización del Proyecto Final de Carrera (PFC), último requisito para obtener los tıtulos de Enginyeria en Inform`atica y M`aster Europeu en Llenguatge i Parla por la Universitat Polit`ecnica de Catalunya (UPC). ...
A Parte Rei Revista De Filosofia, 2006
Eduardo Fernández Villar I. "...tenemos que pensar, lo que se llama pensar, es decir sentir, situ... more Eduardo Fernández Villar I. "...tenemos que pensar, lo que se llama pensar, es decir sentir, situarse y confrontarse antes de permitir el paso de la más pequeña oración principal o subordinada." J.
Uploads
Papers by Eduardo Hermosilla Villar