Papers by Dr Swati Samant
Aim of the study: Many studies from various parts of India have reported scrub typhus with diagno... more Aim of the study: Many studies from various parts of India have reported scrub typhus with diagnosis based on IgM ELISA; however no definite data available for IgM for Scrub Typhus as prognostic indication .Our study gives a correlation of IgM level with the clinical presentations as well as organ involvement and complications thus depicting the prognostication. Material and methods: This descriptive observational investigation was carried out over a time of two years. Hospitalized cases with complaints of Indistinct febrile disease with a lymphadenopathy, organomegaly as well as head pain were taken over a period of five days deprived of a recognizable cause. as probable scrub typhus patients and advised for initial WeilFelix test and scrub IgM level. The spectrum of clinical manifestation and end organ damage were analyzed with scrub typhus serum IgM level. Results:Among 113 patients diagnosed as scrub typhus basing on IgM value, 48 are children (below 14 yrs) and 65 are adults. M...
Indian Journal of Public Health Research and Development, 2018
Indian Journal of Health Sciences and Biomedical Research (KLEU), 2021
INTRODUCTION: Pseudoexfoliation (PXF) syndrome has been known to be a genetically inherited syndr... more INTRODUCTION: Pseudoexfoliation (PXF) syndrome has been known to be a genetically inherited syndrome which generally affects the population above 50 years of age. It further increases the chances of complications during cataract surgery. AIM: In our study, we aim to compare the results of manual small-incision cataract surgery (MSICS) in PXF eyes and controls and report the intraoperative and postoperative outcomes (up to 6 weeks) in both groups. MATERIALS AND METHODS: This was a prospective, observational, nonrandomized study, which was conducted in the ophthalmology department in a tertiary hospital in Eastern India from February 1, 2018, to December 31, 2019. 50 patients with PXF (Group 1) and 50 controls (Group 2) were included in this study and assigned to undergo MSICS. RESULTS: Group 1 patients (with PXF) were found to be significantly of older age (P = 0.0315). Mixed cataract, i.e. with cortical and nuclear sclerosis, was present in 22 (44%) eyes in Group 1 and 31 (62%) eyes...
Clinical and Experimental Optometry
A 32-year-old healthy male presented with painless loss of central vision in the right eye of two... more A 32-year-old healthy male presented with painless loss of central vision in the right eye of two months duration. There was no history of trauma, past ocular surgery, fever, rash, vitiligo or hearing loss. The patient had been diagnosed as active choroiditis elsewhere and was on oral corticosteroids. Best corrected visual acuity in the right eye was 6/60, N18 and in the left eye was 6/6, N6. Anterior segment examination and intraocular pressure were normal in both eyes. Fundus examination of the right eye showed a large creamy yellow subretinal lesion temporal to the foveal centre (Figure 1A). The lesion displayed a central clearing. A few choroidal striae were seen in the macular area. Fundus examination of the left eye was normal (Figure 1B). Fundus fluorescein angiography of the right eye showed an ink-blot type of leak temporal to the foveal centre in the early phase of the angiography (Figure 2A). The leak increased in size and intensity in the later phases of angiography (Figures 2B, 2C). Fundus fluorescein angiography of the left eye was normal. A diagnosis of central serous chorioretinopathy in the right eye was made. The patient underwent focal laser to the leak point in the right eye. Topical Nepafenac (0.1 per cent) was prescribed, to be taken three times per day in the right eye for three weeks. The patient presented for follow up two months after laser therapy. Best corrected visual acuity in the right eye was 6/10, N6. There was complete resolution of the subretinal lesion and choroidal striae. Retinal pigment epithelial alterations were seen at the site of previous lesion.
Asian Journal of Pharmaceutical and Clinical Research, May 1, 2018
Objective: Our hospital, tertiary care hospital in the capital of the state of Odisha, had been w... more Objective: Our hospital, tertiary care hospital in the capital of the state of Odisha, had been witnessing pyrexia of unknown origin, associated with breathlessness, renal, and liver impairment, which did not respond to high antibiotics but to doxycycline; therefore, the present study was undertaken to identify whether scrub typhus is the etiological agent, and thereafter, their characteristic features were further evaluated as an effort in supporting its diagnoses and treating patients accordingly. Methods: A total of 65 adult patients (age >15 years) admitted with pyrexia between April 2015 and October 2017 were evaluated. Immunoglobulin M (IgM) scrub typhus test was done in all these patients. IgM scrub typhus test positive samples were included in the study and various clinical parameters analyzed. Results: Of the 65 patients included in the study, all were found to be positive for IgM antibodies against Orientia tsutsugamushi. The cases were seen mainly in the months between September and November. The common symptoms found were fever, myalgia, breathlessness, rash, and abdominal pain and rarely altered sensorium. The diagnostic features like eschar were found in 23% patients. Nearly, two-thirds of patients had fever more than 7 days and myalgia (76.92%), headache (58.46%). The most common complications were renal failure (20%) followed by pneumonia (10.76%). Laboratory findings of high C-reacting protein (89.23%) and leukocytosis are found in 35.38%. Conclusion: Our results showed that scrub typhus should be considered in the differential diagnosis of pyrexia of unknown origin associated with breathlessness, myalgia, rash, gastrointestinal symptoms, hepatorenal syndrome, or acute respiratory distress syndrome. Empirical treatment with doxycycline may be given in the cases with strong suspicion of scrub typhus.
JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 2018
International Journal of Advances in Medicine
Background: Dengue is a vector borne disease by four different serotypes of dengue virus transmit... more Background: Dengue is a vector borne disease by four different serotypes of dengue virus transmitted by bite of female Aedes mosquito. It is an acute febrile illness characterised by myalgia, joint pain, gastrointestinal manifestations. Complications like dengue hemorrhagic fever (DHF) and Dengue shock syndrome (DSS) , Extended Dengue Syndrome(EDS) may be fatal for patients. Authors analyse different clinical spectrum of of manifestations, complications and correlation bleeding to platelet level.Methods: This study conducted from July 2017 to December 2018 comprising of 100 dengue patients of age more than 15 years in IMS & SUM Hospital.Result: Out of 100 dengue patients’ males 73% and females 27%. From the patients 57% were NS1 Antigen positive, 29% IgM positive, 9% NS1 and IgM positive, 4% IgM and IgG positive and 2 % with all NS1, IgM, IgG positive. In our series in clinical manifestations, all cases (100%) presented with fever, myalgia (78%), headache (53%), rashes (14%), nausea...
Indian Journal of Ophthalmology, 2016
Dermatitis neglecta, a condition of the skin secondary to a primary underlying disease, is an imp... more Dermatitis neglecta, a condition of the skin secondary to a primary underlying disease, is an important diagnosis to be kept in mind as the clinical presentation may mimic a severe disease, but the treatment basically includes patient counseling and personal hygiene.
To evaluate the efficacy of fresh human amniotic membrane for reconstruction in corneal surface d... more To evaluate the efficacy of fresh human amniotic membrane for reconstruction in corneal surface diseases. Material and Methods: 28 eyes of 26 patients with corneal surface disorders were evaluated. Indications for AMT included bullous keratopathy (4 eyes), climatic droplet keratopathy (3 eyes), Steven Johnson syndrome (7 eyes), chemical injury (3 eyes), corneal ulcer (7 eyes), band keratopathy (2 eyes) and shield ulcers (2 eyes). Fresh amniotic membrane was used in all the cases. Result: The age range was from 18-65 years, out of which 15 were males and 11 were females. Success was noted in75% (21/28 eyes) with very few complications in an average follow up period of 6 months. The mean epithelisation time varied from 2-2.4 weeks. Conclusion: Fresh amniotic membrane can reduce inflammation, promote epithelisation and decrease in various corneal surface disorders.
Uploads
Papers by Dr Swati Samant