Papers by Dr. Jigyasa Rana
International Journal of Surgery
Indian Journal of Veterinary Anatomy, 2016
Journal of Pharmacognosy and Phytochemistry, 2019
A female Murrah buffalo of age 2.5 years was presented to the Teaching Veterinary Clinical Comple... more A female Murrah buffalo of age 2.5 years was presented to the Teaching Veterinary Clinical Complex of College of Veterinary Science & A.H., Anjora, Durg, Chhattisgarh with the history of recurrent fever, anorexia, frequent micturition, nervous sign, pale mucous membrane and loss of appetite. On blood smear examination Trypanosoma spp. infection (+++) was observed. The buffalo was treated with diminazene aceturate (7.0 mg/kg) and blood smears were examined after every 24 h showing gradual decrease in the level of parasitaemia followed by complete recovery of animal within a week.
VirusDisease, 2022
Porcine enteric picornaviruses often consequence diarrhoea and nervous complications in pig and p... more Porcine enteric picornaviruses often consequence diarrhoea and nervous complications in pig and pose enormous loss to pig farming. The present study expands the limited Indian data of porcine enteric picornaviruses which is needed for the early implementation of control measures and to check further outbreaks. A total of 398 porcine faecal samples from Uttar Pradesh, Madhya Pradesh, Chhattisgarh and Jharkhand state of India were screened for porcine teschovirus (PTV), porcine sapelovirus (PSV) and enterovirus G (EV-G) by reverse transcriptase-polymerase chain reaction (RT-PCR) using 5′UTR-specific primers. The prevalence of PTV, PSV and EV-G was found to be 12.81% (51/398), 5.77% (23/398) and 24.37% (97/398), respectively. EV-G was relatively higher in circulation in Indian pigs among all the included enteric picornaviruses. Conversely, the concurrent infection of more than one enteric picornavirus was also frequent.
The Indian Journal of Veterinary Sciences and Biotechnology, 2018
The present study was aimed to explore histomorphological changes in the Harderian gland of chick... more The present study was aimed to explore histomorphological changes in the Harderian gland of chicken from 3 day of hatch to 24 day old. The gland was compound tubule-acinar type, consisted of capsule, parenchyma and stroma. In post hatch group of chicks, the gland was surrounded by thin connective tissue capsule from which septae extend that subdivide the gland into lobules of varying size. In the parenchyma of the gland, acini situated at the periphery and tubules at the centre of lobule. The acini were lined by columnar epithelial cells of varying height with basally located nucleus and the tubular systems were lined by a single layer of epithelium varying from columnar to cuboidal. Stroma or interstitial tissue consisted of collagen, fibroblasts, blood vessels, nerves and immune cells (plasma cells and lymphocytes. The plasma cells increased with advancement of age. Secretory units of the gland secreted its material by blebs formation on the luminal surface epithelium at early pos...
Immunohistochemical study was carried on thymus of 30 apparently fresh fertile eggs from 1 to 21 ... more Immunohistochemical study was carried on thymus of 30 apparently fresh fertile eggs from 1 to 21 days of incubation divided into 3 age groups as 1-8 days of incubation (Group I), 9-15 days of incubation (Group II) and 16-21 days of incubation (Group III). It was found that the appearance of thymic lymphocytes began to form at the mid period of incubation. T Lymphocytes were observed in the cortex and medulla region of the thymus and their number increased with advancement of age, which indicated its role in growth and defence against infection in birds.
North-East Veterinarian, 2015
This paper investigates how changes in European banks' credit risk affect their host countries' s... more This paper investigates how changes in European banks' credit risk affect their host countries' sovereign risk by exploring bank-to-sovereign rating spillover effects. Using credit rating data from Standard & Poor's, Moody's, and Fitch for the period ranging from 2002 to 2016, we identify both positive and negative bank-to-sovereign spillover effects, and find the negative rating spillover effect to be more pronounced than the positive one. Further, we provide evidence on differences among the three rating agencies in terms of the occurrence of positive spillovers, and the degree of negative spillovers. Our results are robust to the changes in model specifications with respect to the currency type of ratings, the structure of regression models, and the approach used to link bank and sovereign ratings. Overall, our analysis sheds new light on how information related to systemic risks emanating from the banking sector affects domestic sovereign credit ratings, and thereby complements previous research focusing on the opposite sovereign-to-bank rating transmission channel.
The present study was carried out on biometry of adrenal gland of 36 healthy goats in different a... more The present study was carried out on biometry of adrenal gland of 36 healthy goats in different age groups as Gr. I (1-8 months), Gr. II (8-18 months) and Gr. III (18 months and above). The weight, volume and size of both the glands were recorded. The right adrenal was located in contact with the medial part of the anterior end of right kidney, whereas the left adrenal was observed to be located medial to the caudal venacava and in front of the left kidney. The right adrenal was in the form of a pyramid whereas the left adrenal was slightly curved in young animals and appeared bean shaped in the adults. All dimensions including weight and volume of the adrenal gland showed significant increase with the advancement of age. No significant differences were observed between male and female animals.
Indian Journal of Veterinary Anatomy, 2015
Uttara breed of fowl has evolved through natural selection in indigenous agro-ecological conditio... more Uttara breed of fowl has evolved through natural selection in indigenous agro-ecological conditions and is well adapted to the local environment of Kumaon region of Uttarakhand state, situated at the Himalayan foothills. It is a docile bird to keep and provides an important animal origin food source of high nutritive value to the local inhabitants. The present study was planned to investigate the post hatch development of the absorptive structure and relative thickness of tunics in different segments of the small intestine. Histomorphometry is one of the basic and valuable techniques in histological studies. The present work was designed and carried out to elucidate the histomorphometrical features of the small intestine of Uttara fowl. Analysing the results, it was observed that the mucosa of the intestinal villi was lined by simple columnar epithelium. The entire length of intestinal mucosa was studded with villi of variable shape and size. The villi were longest (1675.0 μm) in du...
Le infezioni in medicina, 2020
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In view of the ever increasing frauds like killing of cows for meat purpose, substitution of meat... more In view of the ever increasing frauds like killing of cows for meat purpose, substitution of meat and presence of unknown animal species in food, it has become necessary to identify the species of animals to protect people from health, economic, religious and legal aspects. Considering the need of identification of domestic animals, PCR based molecular techniques were used. The DNA from Cattle, Buffalo, Sheep and Pig were isolated by alcohol-chloroform method and subjected to PCR assay using species specific primers to observe the band pattern. The present study revealed that PCR assay could differentiate Sheep, Pig, Cattle and Buffalo together. The PCR reaction for species specific primers with DNA extracted from blood as well as muscles samples of Cattle, Buffalo, Sheep and Pig revealed bands at 603; 603; 374 and ≤ 100 base pairs respectively. Therefore the samples were subjected for PCR-RFLP method, wherein it revealed bands at 191 and 169 base pairs for Buffalo samples while Cat...
The objective of this study was to investigate the histomorphological development of the small in... more The objective of this study was to investigate the histomorphological development of the small intestine of Uttara fowl and to examine the changes in the number of goblet cells, argentaffin cell granules and lymphatic nodules by using histochemical techniques. The goblet cells were numerous towards the distal part of the intestine whereas the argentaffin cells and lymphocytes were more in number in the duodenal part. The goblet cells and crypts of Lieberkühn have acid and strongly sulphated mucopolysaccharide secretions. The brush borders as well as the goblet cells of the ileum showed high amount of polysaccharide material. Distribution of non-specific alkaline phosphatase (ALP) enzyme was correlated with age by catalytic histochemistry method. The ALP activity in post hatch chicks gradually increased from proximal to distal end of small intestine within the same age group. The activity also increased with the increasing age of the birds.
The present study was conducted on 40 spleen samples of goat from prenatal to four months and abo... more The present study was conducted on 40 spleen samples of goat from prenatal to four months and above age. The small pieces from spleen were processed for histo-morphological study. The general histo-architecture of spleen showed capsule, trabeculae, red pulp and white pulp in all age groups. The splenic capsule was found to be composed of outer fibrous layer and inner muscular layer. The thickness of capsule was gradually increasing due to increase in thickness of muscular layer with the advancement of age. The components of outer fibrous layer were wavy and intermingled with collagen, reticular and elastic fibres. The elastic fibres however, became short and fragmented with advancement of age. Variation in the concentration of these fibres in capsule with advancement of age was necessary to provide firmness to the organs from outside during postnatal period and to provide elasticity of organ during prenatal and early postnatal stage. The connective tissue trabeculae radiated from ca...
Indian Journal of Animal Research, 2021
Background: The porcine sapelovirus (PSV) is a small, non-enveloped, single-stranded, positive-se... more Background: The porcine sapelovirus (PSV) is a small, non-enveloped, single-stranded, positive-sense, RNA virus of the family Picornaviridae. The PSV infections in pigs have been found associated with diarrhoea, polioencephalomyelitis, pneumonia and reproductive disorders with a high morbidity rate. Despite of its economical importance very few studies are available on the pathology of PSV. The present study was conducted with the aim to investigate the PSV infection and associated pathology in Indian pigs. Methods: Tissue samples along with intestinal content were collected from a total of 78 necropsied cases for histopathological examination and molecular investigation during April 2019 to August 2020. The amplification of 5' UTR region of PSV was carried out via RT-PCR and confirmed by sequencing. The Genetic characterization of Indian isolate of the PSV was done on the basis of viral 5' UTR gene. Result: A total of eight out of 78 cases were found positive for the PSV. C...
Journal of Livestock Science, 2021
In late December 2019, Wuhan city of Hubei province, China faced a newly emerged highly contagiou... more In late December 2019, Wuhan city of Hubei province, China faced a newly emerged highly contagious viral zoonosis mainly characterized by respiratory illness, associated with pneumonia of unknown etiology which claimed many lives. The virus was then provisionally designated as 2019-nCoV by WHO and officially named as Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) by International Committee on Taxonomy of Viruses (ICTV). On 11 Feb 2020, WHO officially announced the name of disease as Coronavirus disease 2019 (COVID-19) and declared the global pandemic on March 11, 2020. Initially, the disease was highly restricted to China but later it scared the world because hugenumber of new cases was reported from the entire world in a short period of 5 months. The dynamic spread of this contagious virus occurred due to exposure of individuals from infected aerosols, community contact and travelling of affected individual worldwide. Bats were thought to be the initial source of this pandemic but the intermediate host of this zoonosis is yet to be established. Many studies reported fever, dry cough, dyspnea, generalized weakness, anosmia, ageusia, muscle ache, rhinorrhea, headache, nausea, conjunctivitis, vomiting and diarrhoea along with many non-specific symptoms as clinical signs of the disease. Many treatment regimen including various antivirals, antibiotics, neutralizing antibodies, repurposed drugs and traditional medicines were being explored but the authorized effective treatment regimen is still awaited. This review is aimed to summarize the current scenario and status of probable treatment options available for ongoing illness caused by the novel coronavirus.
Travel Medicine and Infectious Disease, 2020
Environmental Science and Pollution Research, 2021
Disinfectants and sanitizers are essential preventive agents against the coronavirus disease 2019... more Disinfectants and sanitizers are essential preventive agents against the coronavirus disease 2019 (COVID-19) pandemic; however, the pandemic crisis was marred by undue hype, which led to the indiscriminate use of disinfectants and sanitizers. Despite demonstrating a beneficial role in the control and prevention of COVID-19, there are crucial concerns regarding the large-scale use of disinfectants and sanitizers, including the side effects on human and animal health along with harmful impacts exerted on the environment and ecological balance. This article discusses the roles of disinfectants and sanitizers in the control and prevention of the current pandemic and highlights updated disinfection techniques against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This article provides evidence of the deleterious effects of disinfectants and sanitizers exerted on humans, animals, and the environment as well as suggests mitigation strategies to reduce these effects. Additionally, potential technologies and approaches for the reduction of these effects and the development of safe, affordable, and effective disinfectants are discussed, particularly, eco-friendly technologies using nanotechnology and nanomedicine.
Travel Medicine and Infectious Disease, 2020
Fig. 1. An overview of dexamethasone and its mode of action in COVID-19 patients.
Frontiers in Public Health, 2020
The coronavirus disease 2019 (COVID-19) pandemic wreaked havoc worldwide, with more than 20 milli... more The coronavirus disease 2019 (COVID-19) pandemic wreaked havoc worldwide, with more than 20 million confirmed cases and nearly 0. 75 million deaths as of 10th August 2020. Various factors determine the severity and symptoms of this infection. Older age and underlying diseases are the challenges being faced in controlling and treating COVID-19. In 2019, 703 million of the global population was older than 65 years of age. The estimated mortality due to COVID-19 in people older than 76 years of age is reportedly 18%. Frequent infections in older people, higher disease severity, and increased mortality are major challenges in the implementation of appropriate preventive measures and future strategies to protect against this disease in geriatric population. Poor health status, weak immune function, lowered organ function, increased probability of multiple underlying diseases, and poor attention to personal health can increase the susceptibility to various diseases in the geriatric population. Concerning inadequate immunity, the decrease expression of receptors and exaggerated pathophysiologic responses can be debilitating. However, future studies will reveal the hidden facets in these aspects in this COVID-19 catastrophe. In this article, we reviewed the main concerns of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in the geriatric population, including the risk of acquiring severe COVID-19 resulting in mortality, variation in clinical manifestations, and other pandemic-related concerns. We also discussed the need for increasing attention toward the elderly, taking appropriate prevention and control measures, and considering geriatric-related adjustments in vaccine design and development.
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Papers by Dr. Jigyasa Rana