Creation: The story of the origin and evolution of the universe. [The Physics Teacher 27, 571 (19... more Creation: The story of the origin and evolution of the universe. [The Physics Teacher 27, 571 (1989)]. Jennifer Bond Hickman. Keywords. Communication, education, history, and philosophy. Physics literature and publications. Monographs and collections. ...
Introduction the aim of this study was to develop a programme theory to inform the design of lone... more Introduction the aim of this study was to develop a programme theory to inform the design of loneliness interventions and guide any future evaluations. Methods we undertook a mixed-method evaluation, informed by the realist approach, of different approaches to loneliness in one health and social care system in the East Midlands, UK. We used a combination of documentary analysis, interviews/focus groups with service providers and users and quantitative analysis to develop an initial programme theory. Results common aims of local interventions included enhancing social connectivity, providing emotional support and advice/information; recurring interventions included social activities, emotional support, advice and information, lunch clubs, learning new skills and practical support. None were robustly evaluated. Fifty-six service user or providers were involved in interviews or focus groups, which highlighted the causes of loneliness, preferred services, access to services, thoughts ab...
An extended source of H-beta flux An optical point source has been reported in the field of the v... more An extended source of H-beta flux An optical point source has been reported in the field of the variable X-ray source NewX-1 (1436 +32). We have observed an extended source of H-beta emission in the same field. The flux in the line is measured to be 10-6 erg s-1 cm-2. The distance of the source and its angular size are unknown.
I became a lecturer in astrophysics by chance. As I was completing my postdoc, looking at how one... more I became a lecturer in astrophysics by chance. As I was completing my postdoc, looking at how one could do quantum field theory in the presence of gravity, I contacted various departments to see if there were any lectureships going. From departments of mathematics I was invariably told that the subject was too physical, and from physics departments that it was too mathematical. Astrophysics seemed a better bet, so I offered to give part of the Oxford undergraduate course on what was then the emerging subject of high energy astrophysics. I think I managed to keep a few pages ahead of the students most days. The result was a job offer from Leicester to teach astrophysics.
A new theory of particle production in background gravitational fields is presented as an alterna... more A new theory of particle production in background gravitational fields is presented as an alternative to Hamiltonian diagonalization. We calculate a vacuum-vacuum transition amplitude and identify the expected pair creation rate in terms of the amount by which the modulus of this amplitude differs from unity. The method is applied to some Robertson-Walker cosmological models and is shown to give results differing from those obtained by Hamiltonian diagonalization.
Purpose This paper aims to report on a project to adapt existing material from some modules on su... more Purpose This paper aims to report on a project to adapt existing material from some modules on sustainability delivered face-to-face by the Centre for Interdisciplinary Science to create a non-credit bearing course in sustainability delivered on-line and available to all students at the University. A total of 250 staff and students signed up for the course, 104 completed at least one multiple choice test and 49 completed the essay assignment for the Higher Education Achievement Record (HEAR) recognition. Feedback from students completing the evaluation questionnaire was overwhelmingly positive. The authors reflect on lessons learnt in preparing and delivering the course and the impact on university strategy. Design/methodology/approach The course was piloted in the 2014-2015 academic year. Findings A total of 250 staff and students signed up for the course; 104 completed at least one multiple choice test and 49 completed the essay assignment for HEAR recognition. Feedback from stude...
Recent developments in the Higher Education sector have resulted in the creation of increasing nu... more Recent developments in the Higher Education sector have resulted in the creation of increasing numbers of teaching-focused positions, whose imcumbents are commonly referred to as 'Teaching Fellows'. Individuals in these roles face a variety of unique challenges compared with their more traditional research-focused colleagues and they often lack access to tailored support and mentoring structures. In this report we highlight the creation of the UK Teaching Fellow Network and describe the online community and discussion forum that have been set up to support these individuals. The pilot programme targeted physics Teaching Fellows; below, we outline our plans to expand membership to encompass other STEM subjects in order to promote a content-rich, vibrant and supportive community in the long-term.
Cells can usefully be equated to autocatalytic networks that increase in mass and then divide. To... more Cells can usefully be equated to autocatalytic networks that increase in mass and then divide. To begin to model relationships between autocatalytic networks and cell division, we have written a program of artificial chemistry that simulates a cell fed by monomers. These monomers are symbols that can be assembled into linear (non-branched) polymers to give different lengths. A reaction is catalysed by a particular polymer or 'enzyme' that may itself be a reactant of that reaction (autocatalysis). These reactions are only studied within the confines of the 'cell' or 'reaction chamber'. There is a flux of material through the cell and eventually the mass of polymers reaches a threshold at which we analyse the cell. Our results indicate a similarity between the connectivity of the reaction network and that of real metabolic networks. Developing the model will entail attributing increased probabilities of reactions to polymers that are colocalised to evaluate the consequences of the dynamics of large assemblies of diverse molecules (hyperstructures) and of cell division. To cite this article: M.
Hyperstructures or modules have been proposed to constitute a level of organisation intermediate ... more Hyperstructures or modules have been proposed to constitute a level of organisation intermediate between macromolecules and whole cells. In this model of intracellular organisation, hyperstructures compete and collaborate for existence within the membrane and cytoplasm. Those directly involved in the cell cycle include initiation, replication and division hyperstructures based on DnaA, SeqA and the 2-minute cluster, respectively. During the run-up to initiation, the mass to DNA ratio increases and, we contend, differential gene expression leads to some hyperstructures becoming more active and stable than others. This results in a drop in the diversity of hyperstructures, some of which release DnaA as they dissociate, and a DnaA-initiation hyperstructure forms. Subsequent DNA replication and cell division generate different daughter cells containing different hyperstructures. This has the advantage of increasing the phenotypic diversity of the population. In developing this model, we also invoke hyperstructures in the partitioning of origins of replication.
... On the utility of scale-free networks. Vic Norris 1,2 ,; Derek Raine 3. Article first publish... more ... On the utility of scale-free networks. Vic Norris 1,2 ,; Derek Raine 3. Article first published online: 13 APR 2006. ... 1 Assemblages Moléculaires: Modélisation et Imagerie SIMS FRE CNRS 2829 Faculté de Sciences et Techniques de Rouen 76821 Mont Saint Aignan, France. 2 ...
Creation: The story of the origin and evolution of the universe. [The Physics Teacher 27, 571 (19... more Creation: The story of the origin and evolution of the universe. [The Physics Teacher 27, 571 (1989)]. Jennifer Bond Hickman. Keywords. Communication, education, history, and philosophy. Physics literature and publications. Monographs and collections. ...
Introduction the aim of this study was to develop a programme theory to inform the design of lone... more Introduction the aim of this study was to develop a programme theory to inform the design of loneliness interventions and guide any future evaluations. Methods we undertook a mixed-method evaluation, informed by the realist approach, of different approaches to loneliness in one health and social care system in the East Midlands, UK. We used a combination of documentary analysis, interviews/focus groups with service providers and users and quantitative analysis to develop an initial programme theory. Results common aims of local interventions included enhancing social connectivity, providing emotional support and advice/information; recurring interventions included social activities, emotional support, advice and information, lunch clubs, learning new skills and practical support. None were robustly evaluated. Fifty-six service user or providers were involved in interviews or focus groups, which highlighted the causes of loneliness, preferred services, access to services, thoughts ab...
An extended source of H-beta flux An optical point source has been reported in the field of the v... more An extended source of H-beta flux An optical point source has been reported in the field of the variable X-ray source NewX-1 (1436 +32). We have observed an extended source of H-beta emission in the same field. The flux in the line is measured to be 10-6 erg s-1 cm-2. The distance of the source and its angular size are unknown.
I became a lecturer in astrophysics by chance. As I was completing my postdoc, looking at how one... more I became a lecturer in astrophysics by chance. As I was completing my postdoc, looking at how one could do quantum field theory in the presence of gravity, I contacted various departments to see if there were any lectureships going. From departments of mathematics I was invariably told that the subject was too physical, and from physics departments that it was too mathematical. Astrophysics seemed a better bet, so I offered to give part of the Oxford undergraduate course on what was then the emerging subject of high energy astrophysics. I think I managed to keep a few pages ahead of the students most days. The result was a job offer from Leicester to teach astrophysics.
A new theory of particle production in background gravitational fields is presented as an alterna... more A new theory of particle production in background gravitational fields is presented as an alternative to Hamiltonian diagonalization. We calculate a vacuum-vacuum transition amplitude and identify the expected pair creation rate in terms of the amount by which the modulus of this amplitude differs from unity. The method is applied to some Robertson-Walker cosmological models and is shown to give results differing from those obtained by Hamiltonian diagonalization.
Purpose This paper aims to report on a project to adapt existing material from some modules on su... more Purpose This paper aims to report on a project to adapt existing material from some modules on sustainability delivered face-to-face by the Centre for Interdisciplinary Science to create a non-credit bearing course in sustainability delivered on-line and available to all students at the University. A total of 250 staff and students signed up for the course, 104 completed at least one multiple choice test and 49 completed the essay assignment for the Higher Education Achievement Record (HEAR) recognition. Feedback from students completing the evaluation questionnaire was overwhelmingly positive. The authors reflect on lessons learnt in preparing and delivering the course and the impact on university strategy. Design/methodology/approach The course was piloted in the 2014-2015 academic year. Findings A total of 250 staff and students signed up for the course; 104 completed at least one multiple choice test and 49 completed the essay assignment for HEAR recognition. Feedback from stude...
Recent developments in the Higher Education sector have resulted in the creation of increasing nu... more Recent developments in the Higher Education sector have resulted in the creation of increasing numbers of teaching-focused positions, whose imcumbents are commonly referred to as 'Teaching Fellows'. Individuals in these roles face a variety of unique challenges compared with their more traditional research-focused colleagues and they often lack access to tailored support and mentoring structures. In this report we highlight the creation of the UK Teaching Fellow Network and describe the online community and discussion forum that have been set up to support these individuals. The pilot programme targeted physics Teaching Fellows; below, we outline our plans to expand membership to encompass other STEM subjects in order to promote a content-rich, vibrant and supportive community in the long-term.
Cells can usefully be equated to autocatalytic networks that increase in mass and then divide. To... more Cells can usefully be equated to autocatalytic networks that increase in mass and then divide. To begin to model relationships between autocatalytic networks and cell division, we have written a program of artificial chemistry that simulates a cell fed by monomers. These monomers are symbols that can be assembled into linear (non-branched) polymers to give different lengths. A reaction is catalysed by a particular polymer or 'enzyme' that may itself be a reactant of that reaction (autocatalysis). These reactions are only studied within the confines of the 'cell' or 'reaction chamber'. There is a flux of material through the cell and eventually the mass of polymers reaches a threshold at which we analyse the cell. Our results indicate a similarity between the connectivity of the reaction network and that of real metabolic networks. Developing the model will entail attributing increased probabilities of reactions to polymers that are colocalised to evaluate the consequences of the dynamics of large assemblies of diverse molecules (hyperstructures) and of cell division. To cite this article: M.
Hyperstructures or modules have been proposed to constitute a level of organisation intermediate ... more Hyperstructures or modules have been proposed to constitute a level of organisation intermediate between macromolecules and whole cells. In this model of intracellular organisation, hyperstructures compete and collaborate for existence within the membrane and cytoplasm. Those directly involved in the cell cycle include initiation, replication and division hyperstructures based on DnaA, SeqA and the 2-minute cluster, respectively. During the run-up to initiation, the mass to DNA ratio increases and, we contend, differential gene expression leads to some hyperstructures becoming more active and stable than others. This results in a drop in the diversity of hyperstructures, some of which release DnaA as they dissociate, and a DnaA-initiation hyperstructure forms. Subsequent DNA replication and cell division generate different daughter cells containing different hyperstructures. This has the advantage of increasing the phenotypic diversity of the population. In developing this model, we also invoke hyperstructures in the partitioning of origins of replication.
... On the utility of scale-free networks. Vic Norris 1,2 ,; Derek Raine 3. Article first publish... more ... On the utility of scale-free networks. Vic Norris 1,2 ,; Derek Raine 3. Article first published online: 13 APR 2006. ... 1 Assemblages Moléculaires: Modélisation et Imagerie SIMS FRE CNRS 2829 Faculté de Sciences et Techniques de Rouen 76821 Mont Saint Aignan, France. 2 ...
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