Papers by Crenguta Ioana Feraru
![Research paper thumbnail of [Perimetric changes in advanced glaucoma]](https://a.academia-assets.com/images/blank-paper.jpg)
Oftalmologia, 2011
AIM The evaluation of various perimetric aspects in advanced glaucoma stages correlated to morpho... more AIM The evaluation of various perimetric aspects in advanced glaucoma stages correlated to morpho-functional changes. MATHERIAL AND METHOD: Retrospective clinical trial over a 10 months time period that included patients with advanced glaucoma stages, for which there have been recorded several computerised visual field tests (central 24-2 strategy, 10-2 strategy with either III or V--Goldman stimulus spot size) along with other morpho-funtional ocular paramaters: VA, lOP optic disk analysis. RESULTS We included in our study 56 eyes from 45 patients. In most cases 89% it was an open angle glaucoma (either primary or secondary) Mean visual acuity was 0.45 +/- 0.28. Regarding the perimetric deficit 83% had advanced deficit, 9% moderate and 8% early visual changes. As perimetric type of defect we found a majority with general reduction of sensitivity (33 eyes) + ring shape scotoma. In 6 eyes (10.7%) having left only a central isle of vision we performed the central 10-2 strategy with II...
Experimental and Therapeutic Medicine, 2020
Neovascular age-related macular degeneration (neovascular ARMD) represents only 10% of ARMD cases... more Neovascular age-related macular degeneration (neovascular ARMD) represents only 10% of ARMD cases but is responsible, if untreated, for quick and severe central vision loss due to major macular changes. The presence of choroidal neovascularization (CNV) in one eye is associated with an approximately 10% risk of CNV development in the fellow eye each year. Intravitreal anti-VEGF therapy has quickly evolved as the standard treatment in neovascular ARMD in the last decade due to significant anatomical and functional improvements, especially in the early stages. In many reports an improvement in the untreated fellow eye was mentioned and systemic exposure was soon confirmed for all anti-VEGF agents after unilateral intravitreal injection. In particular, bevacizumab intravitreal injection is followed by a consistent reduction of serum VEGF levels and the drug was shown to have the longest serum half-life raising important debates about its safety. Once bevacizumab was detected in the fel...
Plateau iris is characterized by closing the anterior chamber angle due to a large ciliary body o... more Plateau iris is characterized by closing the anterior chamber angle due to a large ciliary body or due to its anterior insertion that alters the position of iris periphery in respect to the trabecular meshwork. There are two aspects that need to be differentiated: plateau iris configuration and plateau iris syndrome. The first describes a situation when the iris root is flat and the anterior chamber is not shallow, the latter refers to a post laser iridotomy condition in which a patent iridotomy has removed the relative pupillary block, but goniscopically confirmed angle closure recurs without central shallowing of the anterior chamber. Isolated plateau iris syndrome is rare compared to plateau iris configuration. We hereby present two case reports of plateau iris syndrome in young patients who came to an ophthalmologic consult by chance.
Archive of Clinical Cases, 2016
We present the clinical case of a 43 years old female patient, referred to our clinic for a red, ... more We present the clinical case of a 43 years old female patient, referred to our clinic for a red, painful left eye. Multiple bilateral similar attacks were reported by the patient in the last 2 years, for which a diagnosis of conjunctivitis or anterior uveitis was established. At current presentation we found bilateral marked inflammatory reaction in the anterior segment (extensive peripheral iris synechiae, inflammatory membrane in the pupillary area, iris "bombe", pigment dispersion, but no keratic precipitates or cells in the anterior chamber. Intraocular pressure (IOP) was 12 mmHg in OD and 40 mmHg in OS, under topical treatment, started 24 before the current visit. Gonioscopy showed closed angle in both eyes, "openable" in various grades after indentation in all quadrants. Anterior segment ocular coherence tomography (AS-OCT) and ultrasonic biomicroscopy (UBM) suggested anatomical causes for acute angle closure, revealing multiple rolling folds on the iris surface, high insertion onto the scleral wall. Multiple laboratory investigations excluded any potential cause of uveitis, therefore the anatomical theory remained in discussion related to a disproportion between anterior structures leading to angle closure attacks. We performed laser peripheral iridotomy, in this patient with positive outcome: IOP decrease, deepening of the AC, open angle in gonioscopy. Misleading issues in this case confused the initial diagnosis and delayed the adequate treatment.
Oftalmologia (Bucharest, Romania : 1990), 2011
The evaluation of various perimetric aspects in advanced glaucoma stages correlated to morpho-fun... more The evaluation of various perimetric aspects in advanced glaucoma stages correlated to morpho-functional changes. MATHERIAL AND METHOD: Retrospective clinical trial over a 10 months time period that included patients with advanced glaucoma stages, for which there have been recorded several computerised visual field tests (central 24-2 strategy, 10-2 strategy with either III or V--Goldman stimulus spot size) along with other morpho-funtional ocular paramaters: VA, lOP optic disk analysis. We included in our study 56 eyes from 45 patients. In most cases 89% it was an open angle glaucoma (either primary or secondary) Mean visual acuity was 0.45 +/- 0.28. Regarding the perimetric deficit 83% had advanced deficit, 9% moderate and 8% early visual changes. As perimetric type of defect we found a majority with general reduction of sensitivity (33 eyes) + ring shape scotoma. In 6 eyes (10.7%) having left only a central isle of vision we performed the central 10-2 strategy with III or V Goldm...
Oftalmologia, 2011
The evaluation of various perimetric aspects in advanced glaucoma stages correlated to morpho-fun... more The evaluation of various perimetric aspects in advanced glaucoma stages correlated to morpho-functional changes. MATHERIAL AND METHOD: Retrospective clinical trial over a 10 months time period that included patients with advanced glaucoma stages, for which there have been recorded several computerised visual field tests (central 24-2 strategy, 10-2 strategy with either III or V--Goldman stimulus spot size) along with other morpho-funtional ocular paramaters: VA, lOP optic disk analysis. We included in our study 56 eyes from 45 patients. In most cases 89% it was an open angle glaucoma (either primary or secondary) Mean visual acuity was 0.45 +/- 0.28. Regarding the perimetric deficit 83% had advanced deficit, 9% moderate and 8% early visual changes. As perimetric type of defect we found a majority with general reduction of sensitivity (33 eyes) + ring shape scotoma. In 6 eyes (10.7%) having left only a central isle of vision we performed the central 10-2 strategy with III or V Goldmann stimulus spot size. Statistic analysis showed scarce correlation between the visual acuity and the quantitative perimetric parameters (MD and PSD), and variance analysis found present a multiple correlation parameter p = 0.07 that proves there is no liniary correspondence between the morpho-functional parameters: VA-MD(PSD) and C/D ratio. In advanced glaucoma stages, the perimetric changes are mostly severe. Perimetric evaluation is essential in these stages and needs to be individualised.
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Papers by Crenguta Ioana Feraru