Papers by Claudio Damian González
Medicina (Buenos Aires), 2010
El objetivo del presente trabajo fue abordar la problemática de la infección por tuberculosis (TB... more El objetivo del presente trabajo fue abordar la problemática de la infección por tuberculosis (TB) en Trabajadores de la Salud (TS) a través de la experiencia en un programa de prevención y tratamiento de la TB en un Hospital General de Agudos de la Ciudad de Buenos Aires. Los objetivos del Programa fueron implementar acciones de educación para la salud, pesquisa periódica de TS, detección de casos de TB y efectuar acciones de control. Se definió infección TB como PPD 2 UT = 10 mm. Se realizaron dos estudios de prevalencia de infección. En 1998 fue de 31.7% (n = 533) y en 2008 de 35% (n = 670). Enfermería tuvo el mayor porcentaje de infectados. En 2008 se advirtió un aumento de la infección TB en los médicos (p = 0.02). Se estudiaron 45 TS en el grupo que repitió PPD a los tres meses del primer estudio de prevalencia. Se detectaron ochos virajes tuberculínicos (17%), todos en enfermeras. Se evaluaron 163 TS que estuvieron en contacto con 8 casos de TB diagnosticados en TS, 4 de los ...
Work-related asthma Work-Related Asthma (WRA) amounts from 10 to 15% of all forms of adult asthma... more Work-related asthma Work-Related Asthma (WRA) amounts from 10 to 15% of all forms of adult asthma. The objective of this work was to describe a population wi...
La conceptualizacion de la zonificacion espacial es un tema que se viene abordando desde mediados... more La conceptualizacion de la zonificacion espacial es un tema que se viene abordando desde mediados del siglo XIX. En la actualidad, diversas politicas de desarrollo regional hacen uso de este sistema que ha ido cambiando en el tiempo, pasando desde “Teorias de Localizacion” como la denomino Von Thunen en 1826, por los “Distritos Industriales” de Alfred Marshall, hasta los “Cumulos Productivos” o “Cluster” descriptos por Michael Porter a fines del mismo XX y principios del XXI. Los rendimientos decrecientes, los altos costos de transaccion, la importancia relativa cada vez menor de las ventajas comparativas y la baja flexibilidad de transformacion de las grandes organizaciones, volvieron a despertar el interes por la geografia economica. Sin embargo, las cualidades que debe reunir una region para su correcta zonificacion economica siguen siendo eje de debate, asi como los objetivos de desarrollo que deben perseguir. El presente trabajo buscara realizar una breve recopilacion de inform...
PloS one, 2017
Obesity is the principal component in the Metabolic Syndrome (MetS) that determines the progressi... more Obesity is the principal component in the Metabolic Syndrome (MetS) that determines the progression of metabolic complications. Metabolically healthy obese (MHO) individuals seem to be protected against those complications. Telomere length (TL) as a novel marker of cellular aging had a complex relationship to the MetS. The principal aim of this study was to investigate the TL in MHO, and to study the association between TL and the worsening of the metabolic condition. We have determined the absolute TL (aTL) in 400 women (mean age of 46.76 ± 15.47 years; range: 18-86 years), grouped according to the metabolic condition in three groups: metabolically healthy non-obese women (MHNO), MHO and obese women with MetS (MSO); and grouped according to the number of components of MetS. We found that MHO displays significantly higher aTL than MSO (p = 0.033; r = -4.63; 95% CI r = -8.89 / -0.37), but did not differ from MHNO. A decrease in aTL with the progressive increase in the number of MetS ...
Endocrinología, Diabetes y Nutrición, 2017
Lower-income populations are hit harder by the diabetes epidemic as regards both prevalence and t... more Lower-income populations are hit harder by the diabetes epidemic as regards both prevalence and the risk of complications. Food Insecurity is one of the mechanisms through which poverty may predispose people with low socioeconomic status to poorer control and higher complication rates. The United Nations Food and Agriculture Organization defined food security as ''the right to have access to sufficient nutritional and culturally acceptable food choices.'' Adults suffering from diabetes with limited income have a 40% greater chance of having food insecurity and an inadequate blood glucose control. Such patients have a twofold greater risk of developing severe hypoglycemia. In addition, several studies have shown that social vulnerability resulting from food insecurity, low socioeconomic status, low educational levels, and poor health education is an independent risk factor for hypoglycemia, even after conventional predictors are controlled. This review analyzes the literature available on social vulnerability as a non-conventional risk factor for development of hypoglycemia in diabetic subjects.
PLOS ONE, 2016
Introduction and Objective Diabetes is characterized by chronic inflammation, endothelial dysfunc... more Introduction and Objective Diabetes is characterized by chronic inflammation, endothelial dysfunction, increased risk of infections and early cardiovascular disease. By releasing neutrophil extracellular traps (NETs), neutrophils kill bacteria and exert pro-inflammatory and pro-thrombotic activities. Increased NETosis has been found in cross-sectional studies including treated type 2 diabetes mellitus (T2DM) patients. In this study, we determined whether the ability of neutrophils to form NETs differs in diabetic patients pre-and post-hyperglycemic control versus healthy donors (HD), and the relationship between NETosis with pro-thrombotic, pro-inflammatory biomarkers and thrombotic clinical events. Methods Diabetic patients recently diagnosed and after 6 and 12 months of treatment (N = 25) and HD (N = 25) were included. NET formation was studied by microscopy and fluorometry. Nucleosomes, HNE-DNA complexes, von Willebrand factor (vWF), IL6 and TNFα plasma levels were measured by ELISA and P-selectin on the platelet surface was assessed by cytometry. Results Basal levels of NETs in recently diagnosed T2DM patients were higher compared to HD. While TNFα stimulation of control neutrophils resulted in DNA release, patient neutrophils were not responsive. Although glycemia decreased after 6 months of metformin treatment, basal and TNFα and PMA-stimulated NETs reached normal values after 12 months. Compared to controls, nucleosomes, HNE-DNA complexes, IL-6 and TNFα levels were increased in recently diagnosed patients and decreased after 12 months of treatment. P-selectin and vWF levels were similar in both populations.
The Journal of rheumatology, Jul 1, 2016
Optoelectronic up-converter to millimetre-wave band using a heterojunction bipolar phototransistor
European Conference on Optical Communication, 1998
InP-InGaAs three-terminal heterojunction bipolar phototransistor (HPT) is reported as an optoelec... more InP-InGaAs three-terminal heterojunction bipolar phototransistor (HPT) is reported as an optoelectronic mixer for up-converter operation. Taking advantage of the inherent non-linearities of the HPT, a remote optical signal modulated at lower frequency is up-converted to the 30 GHz band. The up-converted signal exhibits a conversion loss and a power level of 8.8 dB and -37.6 dBm, respectively
Inverse association between yerba mate consumption and idiopathic Parkinson's disease. A case–control study
Journal of the Neurological Sciences, 2015
Yerba mate tea is a very common beverage in some countries of South America. We conducted a case-... more Yerba mate tea is a very common beverage in some countries of South America. We conducted a case-control study on an individual basis using hospital records to investigate the association between Parkinson's disease (PD) and yerba mate intake. A case was defined as an age of ≥40years with ≥1year of PD. Each case was individually matched by two controls. Exposure was measured by yerba mate consumption, coffee, tea, and alcohol intake and smoking status. The sample consisted of 223 PD patients (mean age 68years and mean disease duration 7.3years) and 406 controls. There was an inverse association between yerba mate "bombilla" consumption and PD (OR 0.64, 95% CI: 0.54-0.76, p=0.00001). A multivariate analysis with a logistic regression adjusted by sex, alcohol intake and smoking provided the following results: yerba mate (OR 0.63, 95% CI: 0.53-0.76), tea (OR 0.60, 95% CI: 0.42-0.86), coffee (OR 0.51, 95% CI: 0.35-0.73). We found an inverse association between yerba mate consumption and PD. These results led us to hypothesize that yerba mate may have a potential protective role in the development of PD.
High-speed InP/InGaAs heterojunction phototransistor for millimetre-wave fibre radio communications
Conference Proceedings. Eleventh International Conference on Indium Phosphide and Related Materials (IPRM'99) (Cat. No.99CH36362)
We report on the performance of a graded-base InP/InGaAs heterojunction phototransistor (HPT) as ... more We report on the performance of a graded-base InP/InGaAs heterojunction phototransistor (HPT) as a direct photodetector and an optoelectronic up-converter in 30 GHz band, investigated at a wavelength of 1.55 μm. HPT performances were improved according to the optimised base contact design in order to obtain a higher optical gain Gopt up to the millimetre-wave range. It is also shown,
Wireless Sensor Node: monitoring low-rate phenomena using a low-power RF-enabled microcontroller
2007 IEEE International Symposium on Intelligent Signal Processing, 2007
A low-power wireless enabled sensor module built from commercial off-the-shelf components (COTS) ... more A low-power wireless enabled sensor module built from commercial off-the-shelf components (COTS) is presented. This sensor/transmitter module is the basic component of a low cost telemetry system that can monitor low time-constant phenomena, such as temperature and humidity in our implementation, in which energy preservation is a target specification. The heart of the module is an RFPIC microcontroller (MCU) with
Proceedings of the 1999 Particle Accelerator Conference (Cat. No.99CH36366)
We discuss the results of recent impedance measurements for an LHC dump kicker prototype, perform... more We discuss the results of recent impedance measurements for an LHC dump kicker prototype, performed at CERN using the coaxial wire method. The kicker design includes a vacuum barrier consisting of a ceramic chamber internally coated with a thin metallic layer having good electric contact with the external beam pipe. For the bench test the coated ceramic tube was replaced by a kapton foil with a 0.2 µm copper layer having the same DC resistance of 0.7 Ωm. The measurements show that this resistive coating provides a very effective RF screening down to frequencies below 1 MHz, where the skin depth is two orders of magnitude larger than the layer thickness and one could expect full penetration of the electromagnetic fields. We also present simulation results and analytic considerations in agreement with the measurements, showing that the return currents almost entirely flow through the copper layer down to frequencies where the reactive impedance of the kicker elements located behind it becomes comparable to the layer resistance. Finally we discuss the relevance of such coaxial wire measurements to the RF shielding by thin metallic layers in the presence of a higly relativistic proton beam.
Passive remote triggering of the activity cycle of a wireless sensor node: a method of adapting the use of energy of the node to the application
2007 International Conference on Sensor Technologies and Applications - SensorComm 2007, 2007
A passive short-range remote triggered mode of operation for ultra-low power wireless sensor devi... more A passive short-range remote triggered mode of operation for ultra-low power wireless sensor devices is proposed. When a triggering signal or coded sequence is detected, the node is enabled from sleep mode, which it is kept on standby in order to save energy. After a trigger command is received, the node turns on its power-consuming elements. The triggering schemes studied are based on passive circuits that allow ultra-low power operation in standby mode. The trigger detector is made up of two basic elements: a passive tuned filter and an active detector that converts the trigger signal to baseband. The active part of the circuit is a low power comparator that awakens the microcontroller unit of the node when it toggles its output. Two trigger schemes are presented: (a) a low frequency (LF-125 kHz) near field communications (NFC) link and (b) a RF frequency (868 MHz ISM band) link.
Improvement of CBE grown InGaAs/InP HBT's using a carbon doped and compositionally graded base
Conference Proceedings. Eleventh International Conference on Indium Phosphide and Related Materials (IPRM'99) (Cat. No.99CH36362)
InGaAs/lnP heterojunction bipolar transistors (HBT) with a carbon doped base are shown to have lo... more InGaAs/lnP heterojunction bipolar transistors (HBT) with a carbon doped base are shown to have lower gain than those with Be doped base, partly because of lower electron lifetime. In order to keep advantage of the low diffusivity of carbon dopant, a composition graduality is introduced in the base, which significantly improves the current gain of HBT's. This graduality also leads
Scientific reports, Jan 19, 2015
We tested the hypothesis that leukocyte telomere length (LTL) is associated with birth weight in ... more We tested the hypothesis that leukocyte telomere length (LTL) is associated with birth weight in both extremes of abnormal fetal growth: small (SGA) and large for gestational age newborns (LGA). Clinical and laboratory variables of the mothers and the neonates were explored; 45 newborns with appropriate weight for gestational age (AGA), 12 SGA and 12 LGA were included. Whether the differences might be explained by variation in OBFC1 (rs9419958) and CTC1 (rs3027234) genes associated with LTL was determined. A significant association between birth weight and LTL was observed; LTL was significantly shorter in LGA newborns (1.01 ± 0.12) compared with SGA (1.73 ± 0.19) p < 0.005, mean ± SE. Maternal (Spearman R = -0.6, p = 0.03) and neonatal LTL (R = -0.25, p = 0.03) were significantly and inversely correlated with maternal history of arterial hypertension in previous gestations. Neonatal LTL was not significantly associated with either rs9419950 or rs3027234, suggesting that the asso...
This paper is concerned with attacks on communication networks. Attacks may consist of physically... more This paper is concerned with attacks on communication networks. Attacks may consist of physically disabling communication links or flooding links with information in order to prevent legitimate communications. Large-scale attacks have been prevalent in recent years, affecting many commercial and e-commerce sites [11].
Variability reduction with multiweighing proceedings
Top, 1996
ABSTRACT
Thin Solid Films, 2001
Ž. Ž. Large area thin films of Cu In,Ga Se CIGS were grown by sequential sputtering. Photovoltaic... more Ž. Ž. Large area thin films of Cu In,Ga Se CIGS were grown by sequential sputtering. Photovoltaic cells have been fabricated 2 Ž. using these films and the performance has been characterized. The effect of annealing conditions temperature and duration of the CIGS film on the device performance has been investigated. SEM studies of the films correlate the microstructure of the CIGS films with the solar cell efficiency. Cell efficiencies in excess of 10% have been achieved by using optimized annealing conditions. The optical properties of the CIGS films were characterized using Variable Angle Spectroscopic Ellipsometry Ž. Ž. VASE. The Gaussian broadened polynomial superposition GBPS parametric relationship is used to describe the optical properties of CIGS films below, above and through the bandgap energy. The present results show that spectroscopic ellipsometry may be used in situ to monitor and optimize film growth conditions and achieve high efficiencies.
Sensors and Actuators A: Physical, 1994
The microfabricated surface plasmon sensor is a hybrid system that integrates optical, mechanical... more The microfabricated surface plasmon sensor is a hybrid system that integrates optical, mechanical and electronic components. The sensor contains elements that are common to numerous electro-optical systems, creating a miniature optical bench. The microsystem elements include a single-mode optical fiber, a graded index collimating lens, a scanning rotating micro-mirror, a cavity filled with index matching fluid, and a position sensitive photodiode. The elements are both laterally and vertically aligned using multi-substrate bonding and positive component-tocomponent alignment.
RBS characterization of the iridium diffusion in silicon
Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 2000
In this work, the Ir diffusion in Si has been studied in the high concentration regime. Si (100) ... more In this work, the Ir diffusion in Si has been studied in the high concentration regime. Si (100) samples were preamorphized by Si implantation and implanted with Ir with a peak concentration of 8×1021cm−3, below the minimum necessary to the formation of a continuous layer of iridium silicide. The amorphized region of the substrate was regrown by solid phase epitaxy at 550°C. This procedure eliminates the effect of the end of range region of the Ir implant on the diffusion process. After regrowth, the samples were annealed at temperatures in the 800–1000°C range for different times. The Ir concentration profiles and the crystal quality were determined from random and aligned RBS spectra. Annealing at high temperatures causes a snow plow effect of Ir toward the surface of the sample, with a segregation coefficient close to 1. An Ir diffusion mechanism through the defect-free region of the Si substrate is also clearly identified, and a constant value of the diffusion coefficient D is derived for each temperature. The values of D follow an Arrhenius behavior with an activation energy Ea=3.3±0.2eV. This value agrees with the typical ones found in vacancy assisted diffusion mechanisms reported for other species. Comparison of these results with the previously reported activation energy Ea=1.3eV for Ir diffusion from the vapour phase at low concentrations shows that the diffusion mechanism is dependent on the concentration level. The values of D at high concentrations are 6 to 7 orders of magnitude lower than the ones reported for low concentrations.
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Papers by Claudio Damian González