Papers by Christophe Lallement
HAL (Le Centre pour la Communication Scientifique Directe), Jun 7, 2016
HAL is a multi-disciplinary open access archive for the deposit and dissemination of scientific r... more HAL is a multi-disciplinary open access archive for the deposit and dissemination of scientific research documents, whether they are published or not. The documents may come from teaching and research institutions in France or abroad, or from public or private research centers. L'archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d'enseignement et de recherche français ou étrangers, des laboratoires publics ou privés.
Compact Model for Continuous Microfluidic Mixer
While the development of lab-on-chip is increasing, the lack of dedicated computer-aided design t... more While the development of lab-on-chip is increasing, the lack of dedicated computer-aided design tools appears as a bottleneck preventing the emergence of large-scale industrial applications. One of the answer relied on 50 years of CAD experience in microelectronic. Based on this fact, and using this environment, multi-domain libraries (fluidic, biological, chemical) are to be designed. Among other, the development of efficient compact model for microfluidic devices is a first step toward such design tool. This paper deals with a continuous microfluidic mixer. Our model takes as inputs the flow rates and the concentrations of each fluid to mix and returns the flow rate and the concentration profiles across the channel at its output. The model depends also on some physical parameters (e.g. diffusion coefficient of fluids) and mixing channel geometry. The model is validated by comparison with finite-element simulation performed with COMSOL Multiphysics. Comparisons are made on several cases. We demonstrated that the model gives a good estimation of the concentration profile, with an error of less than 2% compared to the finite element simulator.
TechConnect Briefs, May 7, 2006
This paper presents a closed-form compact model for the undoped double-gate (DG) MOSFET under sym... more This paper presents a closed-form compact model for the undoped double-gate (DG) MOSFET under symmetrical operation. This charge-based model aims at giving a comprehensive understanding of the device from the circuit design point of view. Both static and dynamic models are derived in terms of simple analytic relationships based on our new explicit formulation of the mobile charge density. Our approach is derived from physics and relies on the EKV formalism originally developed for bulk MOSFETs. The model takes into account the mobility degradation and the DIBL (Drain-Induced Barrier Lowering) and is valid for devices with channel length down to 100 nm. Comparisons with 2D numerical simulations give evidence for the accuracy of the model. Furthermore, the VHDL-AMS code of the presented model leads to fast simulations, thus demonstrating that the model is well-suited for circuit simulation.
Is SystemC-AMS an appropriate "promoter" for the modeling and simulation of bio-compatible systems?
HAL (Le Centre pour la Communication Scientifique Directe), May 30, 2010
The paper presents an innovative approach for the modeling and simulation of heterogeneous biolog... more The paper presents an innovative approach for the modeling and simulation of heterogeneous biological systems based on SystemC-AMS, an open-source C++ extension to the OSCI SystemC Standard. After some basic notions on synthetic biology, an analogy is drawn between this active field of research and nanoelectronics. The paper then presents the SystemC-AMS Timed DataFlow (TDF) modeling formalism used to model these multidomain devices. It also details the presented case study, a bio-compatible system with feedback consisting of a biological sensor instanciating a T flip-flop BioBrick and a EnFET, a voluntarily simple digital processing unit and an actuator based on the Hodgkin-Huxley neuron model. Some simulation results are given that validate the use of SystemC-AMS as an attractive, open-source and flexible framework for modeling complex bio-compatible systems.
Electro-Thermal Battery Model for Automotive Applications
PCIM Europe digital days 2021; International Exhibition and Conference for Power Electronics, Intelligent Motion, Renewable Energy and Energy Management, May 3, 2021
Identification des paramètres d'un modèle de batterie lithium-ion pour une source hybride de véhicule électrique
HAL (Le Centre pour la Communication Scientifique Directe), Jul 1, 2021
Advancements in DC and RF MOSFET modeling with the EPFL-EKV charge-based model
We discuss new developments of the compact EPFL-EKV charge based model for analog circuit simulat... more We discuss new developments of the compact EPFL-EKV charge based model for analog circuit simulations that are consistent with advanced CMOS technology. The physical foundations of the EKV model and in particular the normalization of the currents and charges are presented and their implications on the model structure are discussed. Based on the hierarchical model description, new effects such as poly gate depletion and quantum confinement can be simply considered as a model generalization. Finally, the consistency of the model is illustrated through the related RF derivation whose equivalent circuit, based on normalized transadmittances and frequencies, can be expressed as a combination of two generic functions only.
A 2D analytical model of threshold voltage for Pi-gate FinFET transistors
International audienc
Annales Des Télécommunications, 1994
Analytic modelling of passive microfluidic mixers
Mathematical Biosciences and Engineering, 2022
This paper deals with a new analytical model for microfluidic passive mixers. Two common approach... more This paper deals with a new analytical model for microfluidic passive mixers. Two common approaches already exist for such a purpose. On the one hand, the resolution of the advection-diffusion-reaction equation (ADRE) is the first one and the closest to physics. However, ADRE is a partial differential equation that requires finite element simulations. On the other hand, analytical models based on the analogy between microfluidics and electronics have already been established. However, they rely on the assumption of homogeneous fluids, which means that the mixer is supposed to be long enough to obtain a perfect mixture at the output. In this paper, we derive an analytical model from the ADRE under several assumptions. Then we integrate these equations within the electronic-equivalent models. The resulting models computed the relationship between pressure and flow rate in the microfluidic circuit but also takes the concentration gradients that can appear in the direction perpendicular...
Efficient Modeling and Simulation of Space-Dependent Biological Systems
Journal of computational biology : a journal of computational molecular cell biology, Jan 9, 2018
We recently demonstrated the possibility to model and to simulate biological functions using hard... more We recently demonstrated the possibility to model and to simulate biological functions using hardware description languages (HDLs) and associated simulators traditionally used for microelectronics. Nevertheless, those languages are not suitable to model and simulate space-dependent systems described by partial differential equations. However, in more and more applications space- and time-dependent models are unavoidable. For this purpose, we investigated a new modeling approach to simulate molecular diffusion on a mesoscopic scale still based on HDL. Our work relies on previous investigations on an electrothermal simulation tool for integrated circuits, and analogies that can be drawn between electronics, thermodynamics, and biology. The tool is composed of four main parts: a simple but efficient mesher that divides space into parallelepipeds (or rectangles in 2D) of adaptable size, a set of interconnected biological models, a SPICE simulator that handles the model and Python script...
An accurate compact model for CMOS cross-shaped Hall effect sensors
Sensors and Actuators A: Physical, 2011
... [22] IC-CAP, Agilent Technologies - IC-CAP 2008 Documentation Set. www.home.agilent.com, Agil... more ... [22] IC-CAP, Agilent Technologies - IC-CAP 2008 Documentation Set. www.home.agilent.com, Agilent Technologies, 2008. ... COMSOL simulations are carried out on a horizontal 20 mx 60 mx 1.5 m cross-shaped Hall sensor, where de SCR modulation is modeled by Eq. ...
Extended charges modeling for deep submicron CMOS
The simulation of deep submicron CMOS cir- cuits operating at high-frequency requires adequate mo... more The simulation of deep submicron CMOS cir- cuits operating at high-frequency requires adequate mod- els representing the dynamic behavior of the transistors. Charges in the device are affected by carrier quantization and polydepletion in the gate. Velocity saturation is one of the short-channel effects that further affect the charges. An analytical MOS transistor (MOST) model for circuit simulation which includes the above effects is described. The charges/transcapacitances expressions show good qualitative behavior at all inversion levels from weak to moderate and strong inversion and have correct asymp- totic behavior. The model agrees well with characteristics obtained from 2D device simulation and measured on deep submicron CMOS technology.
Energy Management Strategy with Adaptive Cut-off Frequency for Hybrid Energy Storage System in Electric Vehicles
2022 IEEE Vehicle Power and Propulsion Conference (VPPC)
An integrated workflow for synthetic biology: from parts to systems and the evolution of new func... more An integrated workflow for synthetic biology: from parts to systems and the evolution of new function-Geoffrey Baldwin p 14:25 A synthetic growth switch and its biotechnological applications-Johannes Geiselmann p 14:45 An open access part toolbox to tune genetic expression in Bacillus subtilis.-Sarah Guiziou p 15:05 Engineering Autonomous Recombinase Switches-Olivier Borkowski p 15:25-16:00 Coffee break 16:00-17:30 Genome engineering-Chairman Alain Blanchard 16:00 Keynote: Laboratory domestication of Escherichia coli-Gyorgy Posfai p 16:40 Reducing the Bacillus subtilis genome.-Etienne Dervyn p 17:05 Using CRISPR/Cas9 tools for the engineering of bacterial genome cloned in yeast-Iason Tsarmpopoulos p
Design Methodology for synthetic biosystems
Synthetic biology is an emerging area of biotechnology for which main applications are in the fie... more Synthetic biology is an emerging area of biotechnology for which main applications are in the field of Health and Environment. However, it suffers from a lack of adapted CAD tools and methodology in order to fulfill efficiently and quickly to the needs of these domains. In this paper, the strong relationship between circuits design in microelectronics and synthetic biology is highlighted. Most of synthesized biodevices behavior can be interpreted and modeled by a “biologic gate”. As a consequence, bigger biosystems might be designed using methods and tools borrowed from microelectronics. These similarities lead to an efficient methodology, using microelectronics design flow, tools and methods, which should allow a top-down approach in synthetic biosystem design. The methodology is illustrated on the design of a biosystem (a T-flipflop), using top-down approach and HDL modeling languages. The proposed methods and its evolution prospects are discussed at the end of the paper.
Gate-level modeling for CMOS circuit simulation with ultimate FinFETs
Proceedings of the 2012 IEEE/ACM International Symposium on Nanoscale Architectures, 2012
ABSTRACT With the high complexity of current digital circuits, the use of gate-level models durin... more ABSTRACT With the high complexity of current digital circuits, the use of gate-level models during the design process is mandatory. For standard CMOS technologies, designers assemble standard cells for which the gate-level model is provided by the founderies. For a given technology, the temporal parameters (such as propagation delays) are constants that can be extracted from experimental measurements. For FinFET-based circuits, such standard cells do not exist. As a consequence, to get predictive simulations of a circuit, the use of low-level model is required. To overcome this problem, we develop a predictive gate-level model for such circuits. To feed the timing parameters of the models, an automated procedure is established. It is based on a new compact model for ultimate FinFET mostly based on physical equations we recently develop. The results obtained with both approaches (compact model and gate-level model) are compared in the last part of the paper. For a digital circuit with about 80 transistors, the results are in accordance. The slight inaccuracy of the gate-level model is largely compensated by a very short simulation time.
EDA inspired open-source framework for synthetic biology
2013 IEEE Biomedical Circuits and Systems Conference (BioCAS), 2013
ABSTRACT The topic of this paper is to develop an open-source framework to help bio-engineers thr... more ABSTRACT The topic of this paper is to develop an open-source framework to help bio-engineers through the different stages of a top-down design process for new artificial biosystems (synthetic biology). The presented tools address the upstream stages of the design, starting from a high-level behavioral description of the targeted biological function and ending with a working assembly of abstract BioBricks performing that very function. For that purpose, EDA (Electronic Design Automation) tools are indeed adapted to synthetic biology. The framework involves three main steps: the interpretation of the high-level description into a netlist of logical functions, the optimization of the netlist with respect to BioBricks capabilities and the automated generation of a SystemC-AMS abstracted simulatable netlist that can be used for further analysis (low-level simulation, optimization ...). Throughout the paper, each stage of the framework is detailed and illustrated with a simple (from a logical point of view) but complex (from the biological viewpoint) example: an in-vivo chemical species regulation system.
Live demonstration: Automated design of artificial biological functions based on fuzzy logic
2014 IEEE Biomedical Circuits and Systems Conference (BioCAS) Proceedings, 2014
Currently, several levels of abstraction can be used to model targeted biological application and... more Currently, several levels of abstraction can be used to model targeted biological application and their associated assembly of elementary biological components (i.e.: BioBricks). The highest one uses the analogy between the behavior of biological mechanism and digital gates. The lowest one uses ordinary differential equations to get accurate and quantitative results. To bridge the gap between these two levels of abstraction, we developed models based on fuzzy logic. This live demonstration is divided in two parts: the first one will consist in the presentation of the algorithm we developed and its illustration on the modeling of different biological systems. The second one is focused on the integration of this algorithm in a complete design flow for synthetic biology. For that, we will present the automation tool that uses fuzzy logic models in order to pick out BioBricks from a database and choose the best assembly according to a given targeted biological function.
Small area charge pump using low voltage capacitors
2014 21st IEEE International Conference on Electronics, Circuits and Systems (ICECS), 2014
There are two main families of charge pumps: parallel and stacking. In this paper, we propose to ... more There are two main families of charge pumps: parallel and stacking. In this paper, we propose to compare a design that is a combination of both with the more common parallel structure. Its main advantage is to make use of only low voltage capacitors as, for a stacking architecture but without its drawback. The hereafter detailed model shows that with the same capacitors the proposed structure would be less efficient. However this handicap is counterbalanced by the fact that low voltage capacitors have a better sheet capacitance. It is demonstrated that the silicon area of the proposed structure is smaller, up to three stages included, compared to a parallel type of charge pump with ideal switches.
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Papers by Christophe Lallement