Papers by Caridad Socorro Castro
Interpretación histopatológica de biopsias por tumores melanocíticos en localizaciones especiales
Revista Española de Patología
Is immunohistochemistry a miracle tool?
DOAJ (DOAJ: Directory of Open Access Journals), Dec 1, 2017
Una mirada desde la ciencia la tecnología y la sociedad a la formación de especialistas médicos
DOAJ (DOAJ: Directory of Open Access Journals), Mar 4, 2021
Medisur, 2018
Molecular studies development in breast cancer has provided arguments to establish subclassificat... more Molecular studies development in breast cancer has provided arguments to establish subclassifications of diagnostic and therapeutic importance, which are bringing to the daily practice the desirability of a patients personalized therapy, to better identify the type of neoplasia. Most current studies seek to phenotypically relate these subtypes to the classic factors reported in the breast cancer anatomopathological report, using conventional hematoxylin and eosin techniques. Immunohistochemistry is a reliable tool that allows subclassification of these neoplasms in different categories using markers, which can establish necessary parameters in diagnosis and prognosis. In this paper the main immunohistochemical markers used in Cienfuegos are presented as well as their usefulness.
Revista Finlay, 2018
Ovary tumor of malignant nature is infrequent in pediatric ages. Dyrgeminomas are not common and ... more Ovary tumor of malignant nature is infrequent in pediatric ages. Dyrgeminomas are not common and constitute around 2 % of all ovary cancers; however, they represent approximately half of the malignant tumors of germinal cells. A case of a 14-year-old patient is presented, with antecedents of skeletal generalized dysplasia, who presented to the doctor complaining of abdominal pain and a palpable mass in the hypogastrium. Imaging exams reported a well-encapsulated tumor with a solid aspect. It was associated to the elevation of seric tumor markers reason for which it was removed and the anatomic-pathologic study concluded the case as a pure right ovary dysgerminoma limited to the organ. It is relatively infrequent in a pediatric age patient carrier of a skeletal dysplasia so it is decided to be published.
Grupo Operativo Provincial de Atención Médica a los enfermos adultos hospitalizados
Medisur 2006; 4(2) RESUMEN El hamartoma pulmonar, descrito en 1904, se presenta como masa de hast... more Medisur 2006; 4(2) RESUMEN El hamartoma pulmonar, descrito en 1904, se presenta como masa de hasta 3 cm de diámetro con ubicación endobronquial o parenquimatosa. La lesión se registra en hombres 2 a 4 veces más que en mujeres y se diagnostica por lo general sobre los 60 años de edad, siempre de forma casual o aparece como hallazgo en las necropsias. Se reporta un caso poco frecuente de hamartoma pulmonar parenquimatoso en una mujer de 42 años de edad. Se describe el cuadro macromicroscópico del espécimen biópsico estudiado, así como sus condicionales clínicas.
Malignant mixed Müllerian tumor
Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2018
<p>Uterine carcinosarcomas or malignant mixed Müllerian tumors are rare neoplasms. They hav... more <p>Uterine carcinosarcomas or malignant mixed Müllerian tumors are rare neoplasms. They have an aggressive behavior and the prognosis depends mainly on the stage of the disease at the time of diagnosis. The progression of these tumors is unfavorable despite being diagnosed and treated in early stages, because they have a greater tendency to early lymphatic dissemination and to pelvic or abdominal recurrence than other endometrial neoplasms. This study presents the case of a 39-year-old, obese and smoker female patient complaining of dark red profuse vaginal bleeding not related to the menstrual cycle and with seven days of progression. She had a history of vaginal bleedings of a 2-year progression and a previous diagnosis of endometrial cystic hyperplasia. The patient was attended to at the ob-gyn department. A total double-adnexectomy abdominal hysterectomy was performed. The anatomopathologic study of the anatomical piece sent to the pathology department confirmed that it was a malignant mixed Müllerian tumor with deep myometrial invasion in more than 50 % of the wall, and a high mitotic index. It was decided to report this case to the medical community given the low frequency of this type of neoplasm, its histopathologic features and the diagnostic challenges it represents for the attending physicians and even for the specialists in pathology.<strong></strong></p>
Medisur, 2018
The heart is very uncommonly affected by neoplasms, most of the times of metastatic nature; they ... more The heart is very uncommonly affected by neoplasms, most of the times of metastatic nature; they are followed in order of frequency by the benign primary neoplasms and finally the malignant ones. Leiomyosarcomas are in the third place within the latter ones. Case Reports with this diagnosis are scarce, so it was decided to put at the scientific community disposal the case of a 79-year-old female patient, of urban origin, type II diabetic for more than 20 years and in addition, a previous history of heart failure about 25 years ago for which she was regularly treated. She was assisted at the Dr. Gustavo Aldereguía Lima General University Hospital in Cienfuegos, where she died. The work presents the case clinical and morphological characteristics and makes a brief allusion to the distinguishing characteristics of this neoplasm in general, in this unusual location.
The pulmonary hamartoma, described in 1904, is presented as a mass of 3 cm of diameter and endobr... more The pulmonary hamartoma, described in 1904, is presented as a mass of 3 cm of diameter and endobronchial or parenchymatous location. The lesion is registered in men two or three times more than in women, and is diagnosed generally over 60 years of age, always casually or appears in necropsies. A non frequent case of this disease is reported in a 42 year old woman. The macro-microscopic frame of the studied biopsic specimen is described, as well as its clinical conditions.
La inmunohistoquímica¿una herramienta milagrosa?
Background: Radio-surgery recently introduced in our hospital environment as a method to treat cu... more Background: Radio-surgery recently introduced in our hospital environment as a method to treat curable malignant lesions of the cervix, constituted a challenge for all the anatomopathologists for the histological distortion it may cause. Objective: To describe a method for the management and interpretation of the biopsy specimen of the neck of the uterus, obtained by radio-surgery. Methods: a flow of coordinated actions was established in the management, on 162 cervix biopsies, from sample taking to final diagnosis during a two years period. Results: This method facilitates the interpretation and topographic location of the lesions, in a way that it clears out the forecasting. It has been evaluated and vouched as satisfactory for its usefulness, easy application, low expense, security, and diagnostic and forecasting confidence.
Molecular studies development in breast cancer has provided arguments to establish subclassificat... more Molecular studies development in breast cancer has provided arguments to establish subclassifications of diagnostic and therapeutic importance, which are bringing to the daily practice the desirability of a patients personalized therapy, to better identify the type of neoplasia. Most current studies seek to phenotypically relate these subtypes to the classic factors reported in the breast cancer anatomopathological report, using conventional hematoxylin and eosin techniques. Immunohistochemistry is a reliable tool that allows subclassification of these neoplasms in different categories using markers, which can establish necessary parameters in diagnosis and prognosis. In this paper the main immunohistochemical markers used in Cienfuegos are presented as well as their usefulness.
Ovary tumor of malignant nature is infrequent in pediatric ages. Dyrgeminomas are not common and ... more Ovary tumor of malignant nature is infrequent in pediatric ages. Dyrgeminomas are not common and constitute around 2 % of all ovary cancers; however, they represent approximately half of the malignant tumors of germinal cells. A case of a 14-year-old patient is presented, with antecedents of skeletal generalized dysplasia, who presented to the doctor complaining of abdominal pain and a palpable mass in the hypogastrium. Imaging exams reported a well-encapsulated tumor with a solid aspect. It was associated to the elevation of seric tumor markers reason for which it was removed and the anatomic-pathologic study concluded the case as a pure right ovary dysgerminoma limited to the organ. It is relatively infrequent in a pediatric age patient carrier of a skeletal dysplasia so it is decided to be published.
The heart is very uncommonly affected by neoplasms, most of the times of metastatic nature; they ... more The heart is very uncommonly affected by neoplasms, most of the times of metastatic nature; they are followed in order of frequency by the benign primary neoplasms and finally the malignant ones. Leiomyosarcomas are in the third place within the latter ones. Case Reports with this diagnosis are scarce, so it was decided to put at the scientific community disposal the case of a 79-year-old female patient, of urban origin, type II diabetic for more than 20 years and in addition, a previous history of heart failure about 25 years ago for which she was regularly treated. She was assisted at the Dr. Gustavo Aldereguia Lima General University Hospital in Cienfuegos, where she died. The work presents the case clinical and morphological characteristics and makes a brief allusion to the distinguishing characteristics of this neoplasm in general, in this unusual location.
Background: Radio-surgery recently introduced in our hospital environment as a method to treat cu... more Background: Radio-surgery recently introduced in our hospital environment as a method to treat curable malignant lesions of the cervix, constituted a challenge for all the anatomopathologists for the histological distortion it may cause. Objective: To describe a method for the management and interpretation of the biopsy specimen of the neck of the uterus, obtained by radio-surgery. Methods: a flow of coordinated actions was established in the management, on 162 cervix biopsies, from sample taking to final diagnosis during a two years period. Results: This method facilitates the interpretation and topographic location of the lesions, in a way that it clears out the forecasting. It has been evaluated and vouched as satisfactory for its usefulness, easy application, low expense, security, and diagnostic and forecasting confidence.
Los métodos de estudio anatomopatológicos desde una mirada histórica, social y contextualizada
El surgimiento y desarrollo de los metodos de estudio anatomopatologicos guarda una estrecha rela... more El surgimiento y desarrollo de los metodos de estudio anatomopatologicos guarda una estrecha relacion con el desarrollo cientifico- tecnico alcanzado por la sociedad. Los metodos tradicionales empleados para el estudio anatomopatologico de las enfermedades se han enriquecido con las nuevas tecnologias, lo que ha favorecido su conocimiento mas profundo, en particular el de las neoplasias, una de las primeras causas de muerte en Cuba y en el mundo. En el presente trabajo se hace una panoramica sobre el desarrollo historico de estos diferentes metodos y su impacto en los procesos de asistencia y educacion medica. Se hace una reflexion sobre la necesidad de fortalecer la formacion para el uso adecuado del metodo clinico y para la indicacion justificada e interpretacion acertada de los resultados de los examenes que, de manera tradicional, han hecho posible el diagnostico y la valoracion del pronostico y la terapeutica, evitando de esta manera el uso irracional de otras tecnologias que e...
Las neoplasias malignas del rinon representan alrededor del 2 % de todos los canceres, el carcino... more Las neoplasias malignas del rinon representan alrededor del 2 % de todos los canceres, el carcinoma de celulas renales es el mas frecuente dentro de este grupo con una frecuencia del 80 al 90 %. El adenocarcinoma de pelvis renal es una neoplasia muy rara, que se presenta en menos del 1 % de los pacientes con neoplasias malignas renales, asociada, la mayoria de las veces, a procesos inflamatorios del organo y litiasis. Por tales razones se decidio la publicacion de un caso clinico diagnosticado en el Departamento de Anatomia Patologica del Hospital General Universitario Dr. Gustavo Aldereguia Lima, de Cienfuegos, con esta variante histologica de cancer renal, en una mujer en la cuarta decada de la vida.
Consideraciones sobre autopsia desde una perspectiva ciencia, tecnología y sociedad
Autopsy or necropsy is a method of anatomical-pathological study with a proven scientific and soc... more Autopsy or necropsy is a method of anatomical-pathological study with a proven scientific and social value that arose in certain social conditions. Its development has been influenced by changing cultural, religious, ethical, political and economic values according to time and country, and as all technologies, is not exempt from social and environmental risks. In spite of this, in the reviewed literature, any work has been found in which a study is made on the subject of autopsy with a focus on science, technology and society. This is the purpose of the present work. For that, an updated review was carried out on the subject and it specifies the social conditions that made possible its emergence and development, the influence of culture and religion, its risks and, finally, some ethical considerations on its practice are made.
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Papers by Caridad Socorro Castro