Creatine kinase (CK) is located in an isoenzyme-specific manner at subcellular sites of energy pr... more Creatine kinase (CK) is located in an isoenzyme-specific manner at subcellular sites of energy production and consumption. In muscle cells, the muscletype CK isoform (MM-CK) specifically interacts with the sarcomeric M-line, while the highly homologous brain-type CK isoform (BB-CK) does not share this property. Sequence comparison revealed two pairs of lysine residues that are highly conserved in M-CK but are not present in B-CK. The role of these lysines in mediating M-line interaction was tested with a set of M-CK and B-CK point mutants and chimeras. We found that all four lysine residues are involved in the isoenzyme-specific M-line interaction, acting pair-wise
I POUTK AL KCONOMY OF TH KDUCATIONAI, PROfKSS Studies in I'nhlk (hoi. 1. 2 I< duel b\ don... more I POUTK AL KCONOMY OF TH KDUCATIONAI, PROfKSS Studies in I'nhlk (hoi. 1. 2 I< duel b\ don I nllm. k kluwer the language of science ... The Political Economy of Rent-Seeking Thi s One Z2H3-U3A-HSTN ... Topics in Regulatory Economics and Policy Series Editor: ...
The interaction between monetary and fiscal policy is at the heart of macroeconomics, but traditi... more The interaction between monetary and fiscal policy is at the heart of macroeconomics, but traditional analysis often ignores the institutional aspects. In recent years a developing I iterature has concentrated on issues such as the influence of central bank independence on the conduct of monetary policy, and as a part of this, the extent to wh'ich the central bank accommodates government fiscal pojjcy. Much less has been done, however, to jnVestigate the reverse interactjon: the extent to which central bank independence influences the formation of fiscal policy. This paper concentrates pnimarily on that channel of jnfluence, and finds some support for the case that fiscal policies are indeed affected by the independence of the centr"al bank. Fi scal defjcjts, for examp'le, may therefore be lowelin countries with more independent central banks because of the greater prospect that monetary policy wilI not be as accommodative of those def icits.
Creatine kinase (CK) is located in an isoenzyme-specific manner at subcellular sites of energy pr... more Creatine kinase (CK) is located in an isoenzyme-specific manner at subcellular sites of energy production and consumption. In muscle cells, the muscletype CK isoform (MM-CK) specifically interacts with the sarcomeric M-line, while the highly homologous brain-type CK isoform (BB-CK) does not share this property. Sequence comparison revealed two pairs of lysine residues that are highly conserved in M-CK but are not present in B-CK. The role of these lysines in mediating M-line interaction was tested with a set of M-CK and B-CK point mutants and chimeras. We found that all four lysine residues are involved in the isoenzyme-specific M-line interaction, acting pair-wise
I POUTK AL KCONOMY OF TH KDUCATIONAI, PROfKSS Studies in I'nhlk (hoi. 1. 2 I< duel b\ don... more I POUTK AL KCONOMY OF TH KDUCATIONAI, PROfKSS Studies in I'nhlk (hoi. 1. 2 I< duel b\ don I nllm. k kluwer the language of science ... The Political Economy of Rent-Seeking Thi s One Z2H3-U3A-HSTN ... Topics in Regulatory Economics and Policy Series Editor: ...
The interaction between monetary and fiscal policy is at the heart of macroeconomics, but traditi... more The interaction between monetary and fiscal policy is at the heart of macroeconomics, but traditional analysis often ignores the institutional aspects. In recent years a developing I iterature has concentrated on issues such as the influence of central bank independence on the conduct of monetary policy, and as a part of this, the extent to wh'ich the central bank accommodates government fiscal pojjcy. Much less has been done, however, to jnVestigate the reverse interactjon: the extent to which central bank independence influences the formation of fiscal policy. This paper concentrates pnimarily on that channel of jnfluence, and finds some support for the case that fiscal policies are indeed affected by the independence of the centr"al bank. Fi scal defjcjts, for examp'le, may therefore be lowelin countries with more independent central banks because of the greater prospect that monetary policy wilI not be as accommodative of those def icits.
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