Papers by Ayush Shrivastava
Journal of Hypertension, 2017
Background: Sickle-cell disease (SCD) is an inherited hemoglobin childhood disorder, frequently c... more Background: Sickle-cell disease (SCD) is an inherited hemoglobin childhood disorder, frequently complicated by pulmonary hypertension and cardiac involvement. Tissue Doppler imaging is the simple indices for the assessment of the cardiac function. Aim: To evaluate cardiac function by means of echocardiography in SCD children. Study Design: Case control study Methods: 30 children with SCD were compared with 30 age-matched healthy controls. Myocardial wall motion velocities at the lateral mitral annulus and the junction between the medial mitral annulus and the interventricular septum were assessed during systole (Sa), early diastole (Ea), and late diastole (Aa) through a four-chamber view using pulsed doppler echocardiography. The ejection fraction and shortening fraction were also estimated. Results: The early diastolic trans-tricuspid peak flow velocity was greater in the SCA patients than in the controls. Assessment of the lateral mitral and tricuspid annulus peak velocities by pu...
Indian Journal of Science and Technology, 2021
Background/Objective: The study aimed to assess the level of awareness of radiation safety amongs... more Background/Objective: The study aimed to assess the level of awareness of radiation safety amongst the Healthcare Professionals in the Private Hospital of Vadodara. Radiation protection tries to avoid the detrimental effects of ionizing radiation by reducing unnecessary radiation exposure. With the increased utilization of radiological investigations, it is essential for referrers to be aware of the harms associated with ionizing radiation to avoid unnecessary exposure for Healthcare Professionals. Methods/Statistical Analysis: This descriptive cross-sectional study in nature where the Healthcare Professionals who are willing to participate will be included in the study. In evaluating the level of awareness 62 Healthcare professionals we used close-ended structured questionnaire which include 8 statements was used for evaluating radiation safety status. The questionnaires used included personal and general questions and its validity and reliability had been confirmed. Findings: A total of 62 healthcare professionals participated in the study. The majority of individual participants whose age is between 20-30 Years, their awareness regarding radiation safety is very well. The participants whose experience between 1-5 years having more knowledge about radiation safety as compared to the other groups whose experience is less than 6 months and greater than 5 years. 90% of the participants were aware about the radiation safety policy of the hospital so it can be stated that the p values of the Chi-square Test are higher than the significant value of 0.05. Novelty/Applications: The study addresses an important aspect which is related to the operational quality of the hospital. Radiation safety is an area of concern because of the safety threats faced by the staff, patients and patient relatives. Assessing the level of awareness among the staff will help in better and planned preparedness of hospital with respect to radiation safety.
2017 2nd International Conference on Image, Vision and Computing (ICIVC), 2017
Early diagnosis of breast cancer can improve the survival rate by detecting cancer at initial sta... more Early diagnosis of breast cancer can improve the survival rate by detecting cancer at initial stage. In this paper, an efficient computer-based mammogram retrieval system is proposed, which helps in early diagnosis of breast cancer by comparing the current case with past cases. The proposed steps include cropping of mammograms, feature extraction using local binary pattern (LBP) and k-mean clustering. Using LBP, k-mean generates the clusters based on the visual similarity of mammograms. Further, query image features are matched with all cluster representatives to find the closest cluster. Finally, images are retrieved from this closest cluster using Euclidean distance similarity measure. So, at the searching time the query image is searched only in small subset depending upon cluster size and is not compared with all the images in the database, reflects a superior response time with good retrieval performances. Experiments on benchmark mammography image analysis society (MIAS) datab...
life science journal, 2020
Ionizing radiation causes lethal injuries either directly or indirectly inducing damage to the bi... more Ionizing radiation causes lethal injuries either directly or indirectly inducing damage to the biological macromolecules, most importantly the genetic material or DNA. Cells transiently halt their cell cycle progression to provide sufficient time for repair machinery to act on for the repair of radiation-induced DNA damages. This may include delay in replication or S-phase of cell cycle besides activating other cell cycle checkpoints. Multiple replicons (replicon cluster equivalent to a chromosome band) along the length of a chromosome fire in a definite pattern for the timely completion of replication. Histone deacetylase inhibitors (HDACi) have been shown to alter the pattern of DNA replication origin activity including earlier replication in S-phase of normally late replicating chromosome bands. This may also indicate an acceleration of repair steps since DNA damage acts as an impediment for replication. Trichostatin A (TSA), a well-known HDACi, was studied for its effect on repl...
ArXiv, 2021
Interactive robots navigating photo-realistic environments face challenges underlying vision-and-... more Interactive robots navigating photo-realistic environments face challenges underlying vision-and-language navigation (VLN), but in addition, they need to be trained to handle the dynamic nature of dialogue. However, research in Cooperative Vision-and-Dialog Navigation (CVDN), where a navigator interacts with a guide in natural language in order to reach a goal, treats the dialogue history as a VLN-style static instruction. In this paper, we present VISITRON, a navigator better suited to the interactive regime inherent to CVDN by being trained to: i) identify and associate object-level concepts and semantics between the environment and dialogue history, ii) identify when to interact vs. navigate via imitation learning of a binary classification head. We perform extensive ablations with VISITRON to gain empirical insights and improve performance on CVDN. VISITRON is competitive with models on the static CVDN leaderboard. We also propose a generalized interactive regime to fine-tune an...
Pediatric Education and Research
International Journal of Contemporary Pediatrics, Dec 21, 2017
Perinatal asphyxia word derived from the Greek word aspyxos, meaning born without an evident puls... more Perinatal asphyxia word derived from the Greek word aspyxos, meaning born without an evident pulse, is one of the most important causes of fetal distress. Inspite of major advances in technology and knowledge of fetal and perinatal medicine, it is one of the significant causes of mortality and long-term morbidity. Asphyxia may have serious effects on many major and vital organs of neonates and can lead to respiratory distress syndrome, disseminated intravascular coagulation, necrosis of subcutaneous fat, myocardial ischemia, adrenal hemorrhage, metabolic complications, acute tubular necrosis, neurological complications such as brain paralysis, convulsion and reduce in learning. 1-3 Asphyxia is one of the main causes of infant mortality and chronic neurologic disabilities in survived neonates. This condition occurs in 2-10% of deliveries. 4-5 According to the reports of the World Health Organization (WHO) in developing countries, three percent of new-borns (6.3 million people) suffer from moderate or severe asphyxia, although 23% of them (840 000 people) die and approximately the same number of ABSTRACT Background: World health organization (WHO) has defined perinatal asphyxia as a failure to initiate and sustain breathing at birth. HIE is one of the most common complication in an asphyxiated neonate because of its serious long term neuromotor sequalae among the survivors. Nucleated red blood cells (NRBC) count in umbilical cord of newborns is been suggested as a sign of birth asphyxia. As the present markers are not accurate in diagnosis and assessing the severity of fetal asphyxia, this study was undertaken to find the values of NRBCs in normal and asphyxiated neonates and the correlation of NRBCs with birth asphyxia. Methods: Eighty neonates with asphyxia along with eight healthy newborns were undertaken for two years study period. Maternal and neonatal information was recorded follow by clinical and laboratory evaluation. NRBC levels was determined per 100 white blood cells (WBC). After discharge, immediate follow-up of asphyxiated infants was performed. Neonates were divided into two groups, with favorable and unfavorable outcome based on discharge or death. Results: We observed that NRBC count with more than 10 per 100 WBC/mm 3 , had sensitivity of 88.75% and specificity of 100% in predicting complications of asphyxia, while in NRBC count with more than 10, the sensitivity and specificity were 88.75% and of 100%, respectively. Conclusions: We demonstrate that NRBC/100 WBC can be used as prognostic marker for neonatal asphyxia, which in combination with the severity of asphyxia could indicate high infant mortality, immediate outcome and complications of asphyxia
International Journal of Contemporary Pediatrics, 2016
Background: The severity of birth asphyxia can be predicted by APGAR score and umbilical cord blo... more Background: The severity of birth asphyxia can be predicted by APGAR score and umbilical cord blood pH. The Nucleated Red Blood Cells (NRBCs) in the cord blood at birth emerged as a newer predictor of birth asphyxia. This study was conducted to find the correlation of cord blood Nucleated Red Blood Cell (NRBC) count with the severity of birth asphyxia and its immediate outcome in term newborns. Methods: An observational hospital based prospective case control study was conducted at inborn NICU, Bal Chikitsalya, RNT Medical College, Udaipur (Raj.) INDIA from March 2015 to September 2015. Total 100 term newborns including 50 as cases (with birth asphyxia) and 50 as controls (normal babies) were enrolled for the study. The cord blood was collected immediately after birth for the measurement of NRBC/100 WBC count and pH value. All the enrolled cases were admitted in NICU and observed for the immediate neurological outcome. The correlation of cord blood NRBC count with APGAR scores, cord blood pH and outcome was analysed statistically. Results: The mean NRBC (NRBC/100 WBC) count was 17.82±19.55 (range from 0-102) in case group and 1.42±3.26 (range from 0 to 18) in control group (p < 0.001). A statistically significant negative correlation of NRBC count was found with severity of birth asphyxia. Conclusions: A simple, cheap, rapid and non-invasive test of NRBC count from umbilical cord blood correlates well with APGAR score and cord blood pH to predict the severity of birth asphyxia and immediate outcome.
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Papers by Ayush Shrivastava