Increasing technology, globalization and several other external connections should render medical... more Increasing technology, globalization and several other external connections should render medical tourism a large part of the rise of global medical treatment. There is extensive proof that healthcare organizations order medical travel agencies to find vendors that are trustworthy and to allow trouble-free travel arrangements to prevent critical preparations. For international care, such facilitators play a significant role in including prospective patients in one nation and medical providers in another. To date, literature on medical tourism has concentrated mostly exclusively on doctors and healthcare professionals. Otherwise, there was no scientific knowledge of the important contribution by Medical Travel Enabler to the health care industry. The moderating role of medical travel facilitators will also be discussed because of the increasing number of hospitals travelers. This paper explores or to what degree the medical tourism facilitators help the regional culture in medical tourism. To both health practitioners and companies involved in the area and future scientists it is also advantageous.
Tea (Camellia sinensis L.) is considered as to be one of the most consumed beverages globally and... more Tea (Camellia sinensis L.) is considered as to be one of the most consumed beverages globally and a reservoir of phytochemicals with immense health benefits. Despite numerous advantages, tea compounds lack a robust multi-disease target study. In this work, we presented a unique in silico approach consisting of molecular docking, multivariate statistics, pharmacophore analysis, and network pharmacology approaches. Eight tea phytochemicals were identified through literature mining, namely gallic acid, catechin, epigallocatechin gallate, epicatechin, epicatechin gallate (ECG), quercetin, kaempferol, and ellagic acid, based on their richness in tea leaves. Further, exploration of databases revealed 30 target proteins related to the pharmacological properties of tea compounds and multiple associated diseases. Molecular docking experiment with eight tea compounds and all 30 proteins revealed that except gallic acid all other seven phytochemicals had potential inhibitory activities against these targets. The docking experiment was validated by comparing the binding affinities (Kcal mol −1) of the compounds with known drug molecules for the respective proteins. Further, with the aid of the application of statistical tools (principal component analysis and clustering), we identified two major clusters of phytochemicals based on their chemical properties and docking scores (Kcal mol −1). Pharmacophore analysis of these clusters revealed the functional descriptors of phytochemicals, related to the ligand-protein docking interactions. Tripartite network was constructed based on the docking scores, and it consisted of seven tea phytochemicals (gallic acid was excluded) targeting five proteins and ten associated diseases. Epicatechin gallate (ECG)-hepatocyte growth factor receptor (PDB id 1FYR) complex was found to be highest in docking performance (10 kcal mol −1). Finally, molecular dynamic simulation showed that ECG-1FYR could make a stable complex in the near-native physiological condition.
2017 31st International Conference on Advanced Information Networking and Applications Workshops (WAINA), 2017
Melanoma is one of those skin cancers whichcan be fatal. So, the segmentation of lesions from the... more Melanoma is one of those skin cancers whichcan be fatal. So, the segmentation of lesions from the digitalimages becomes a crucial step in analysis and diagnosis of askin cancer using image processing techniques. This workproposes a technique for automatic segmentation of lesionfrom the digital dermoscopic images using adaptive thresholdmaking the process invariant and robust. The statisticalfeatures like standard deviation and mean are used topreprocess and segment the lesions completely in an automaticmanner. The use of image processing techniques, such asaverage filtering for removal of hair and skin scales, mathematical morphology to reject the false positives havebeen successfully able to accurately segment the lesion fromthe images. The results are significant and indicate that themethod has good accuracy. An average correlation of 90% andaverage overlapping score of 83% has been obtained.
2018 4th International Conference on Computational Intelligence & Communication Technology (CICT), 2018
Melanoma can prove fatal if not diagnosed at early stage. Computer aided identification of diseas... more Melanoma can prove fatal if not diagnosed at early stage. Computer aided identification of diseases can equip normal people in performing a screening test of diseases. The accurate lesion segmentation plays a crucial role in correct diagnosis of skin diseases. This work proposes a skin lesion segmentation method using statistical analysis and bit plane slicing. Hole filling operation is competent enough to sufficiently reject the noisy pixels from the finally segmented image. The results of skin lesion segmentation obtained from the proposed algorithm has been compared with the annotated images available with the database. The results arepresented in form of overlapping score and correlation coefficient. An average overlapping score and correlation coefficient of 91.59% and 92.07%, respectively, is obtained from the proposed algorithm. Also, an image based performance analysis of segmented lesion has been done and an average sensitivity of 94.33% has been achieved. The results are convincing and suggests that the proposed work can be used for some real-time application.
Exponential development into ICT and Web technology has had significant effect upon business & in... more Exponential development into ICT and Web technology has had significant effect upon business & infrastructure distribution structures of the current global economy. Electronic -Hospital Management Systems (EHMS) offer benefits of streamlined procedures, efficient compliance & tracking, quality patient service, strict cost containment and expanded efficiency. Healthcare Insurance Portability & Accountability Act ( HIPAA) provisions, that have established standard of healthcare sector in management of medical reports as well as protection of patient details. The research focused on identifying success metrics for Hospital Information Systems (HIS), summing up current widely accepted guidelines & procedures such as Health Level Seven (HL7) requirements for shared communications communication, HIS elements, etc. For several customized variants of E-HMS Systems & HIS upon marketplace, a basic module edition of E-HMS was meant to offer simple understanding to analysts and business special...
This dissertation is composed of two essays. In the first essay, using a panel of establishments ... more This dissertation is composed of two essays. In the first essay, using a panel of establishments from the Annual Survey of Industries (ASI), I study the impact of the 1991 trade liberalization episode in India on the employment share of women. Contrary to the predictions of a taste-based discrimination model, I find that establishments exposed to larger output tariff reductions and import competition reduced the share of female workers. I also I would like to thank my advisor Chinhui Juhn without whom this work would not have been possible. Her guidance at every step, enthusiastic discussions and painstaking corrections have been invaluable contributions. I would also like to thank her for the financial assistance provided by her to collect data for this work. She has taught me to express my ideas in a logical and coherent manner. I would also like to thank Aimee Chin for always being there and giving me the perfect sets of advises both on the professional and personal front. She introduced me to the field of research in empirical microeconomics. I am grateful to her for her patient advise on all matters. I thank Elaine Liu for pushing me hard and making me do my best. I am grateful to her for teaching me to work in an organized fashion. I thank all my dissertation committee members for their comments, corrections and suggestions throughout the course of this work.
Increasing technology, globalization and several other external connections should render medical... more Increasing technology, globalization and several other external connections should render medical tourism a large part of the rise of global medical treatment. There is extensive proof that healthcare organizations order medical travel agencies to find vendors that are trustworthy and to allow trouble-free travel arrangements to prevent critical preparations. For international care, such facilitators play a significant role in including prospective patients in one nation and medical providers in another. To date, literature on medical tourism has concentrated mostly exclusively on doctors and healthcare professionals. Otherwise, there was no scientific knowledge of the important contribution by Medical Travel Enabler to the health care industry. The moderating role of medical travel facilitators will also be discussed because of the increasing number of hospitals travelers. This paper explores or to what degree the medical tourism facilitators help the regional culture in medical to...
Proceedings of the 2nd International Conference on Applications of Intelligent Systems, 2019
Melanoma is a fatal skin anomaly which can be treated if diagnosed under benign condition. The ac... more Melanoma is a fatal skin anomaly which can be treated if diagnosed under benign condition. The accuracy of cancer detection depends directly on the accuracy of lesion segmentation. This work proposes an imaging method for lesion segmentation from dermoscopic images using inpainting, edge detection and intensity based threshold. The use of mathematical morphological operations has been done to remove noisy pixels post segmentation. The use of proposed techniques has made the method less complex and computationally efficient and can work in real-time. An average Jaccard index value of 89.2383% and correlation coefficient of 92.5271% has been achieved using the proposed method. The results are convincing and guides in the direction of usage of proposed algorithm as subset of some real time application for melanoma detection.
2016 Ninth International Conference on Contemporary Computing (IC3), 2016
Exudates are one of the abnormalities present on the retina which can be used in identification o... more Exudates are one of the abnormalities present on the retina which can be used in identification of diseases like Diabetic Retinopathy and Macular Edema. There arises a need for automated and correct segmentation of exudates from fundus images. This paper proposes an automated computer vision technique for efficient exudates segmentation from fundus images. The proposed method segments the exudates using an adaptive intensity based threshold which is selected by strategically combining first order statistical parameters and local thresholding method. The proposed technique correctly detects exudates from the fundus images with an average computation time of 9 seconds. The proposed method is computationally strong and can be used in image processing based applications for diagnosis of ocular diseases. Proposed Algorithm Retinal exudates are lipid residues that leak from damaged capillaries and commonly seen in diabetic retinopathy, retinal vein occlusions and choroid neo-vascular membranes. Exudates may be considered small regions of bright yellow color in the eye which can be rich in protein and fat.
Using a panel of establishments from the Annual Survey of Industries (ASI), I study the impact of... more Using a panel of establishments from the Annual Survey of Industries (ASI), I study the impact of the 1991 trade liberalization episode in India on the employment share of women. Contrary to the predictions of a taste-based discrimination model, I find that establishments exposed to larger output tariff reductions and import competition reduced the share of female workers. I also find that input tariff reductions neither raised nor reduced female employment share. The negative association between output tariff reductions and female employment appears to be driven by two factors. First, establishments facing larger output tariff declines engaged in more skill-upgrading which worked against women (who are less skilled in terms of measured education). Second, establishments facing larger tariff declines increased the number of shifts per worker. Since women in India are prohibited by law from working long hours and night shifts, this hours-constraint appears to have reduced relative employment of women. I find this effect to be particularly large among “big and private” establishments. This paper is the first to provide empirical evidence of how a well intentioned policy of limiting female work hours might have unintended side effects. JEL: D3, F15,J16
Increasing technology, globalization and several other external connections should render medical... more Increasing technology, globalization and several other external connections should render medical tourism a large part of the rise of global medical treatment. There is extensive proof that healthcare organizations order medical travel agencies to find vendors that are trustworthy and to allow trouble-free travel arrangements to prevent critical preparations. For international care, such facilitators play a significant role in including prospective patients in one nation and medical providers in another. To date, literature on medical tourism has concentrated mostly exclusively on doctors and healthcare professionals. Otherwise, there was no scientific knowledge of the important contribution by Medical Travel Enabler to the health care industry. The moderating role of medical travel facilitators will also be discussed because of the increasing number of hospitals travelers. This paper explores or to what degree the medical tourism facilitators help the regional culture in medical tourism. To both health practitioners and companies involved in the area and future scientists it is also advantageous.
Tea (Camellia sinensis L.) is considered as to be one of the most consumed beverages globally and... more Tea (Camellia sinensis L.) is considered as to be one of the most consumed beverages globally and a reservoir of phytochemicals with immense health benefits. Despite numerous advantages, tea compounds lack a robust multi-disease target study. In this work, we presented a unique in silico approach consisting of molecular docking, multivariate statistics, pharmacophore analysis, and network pharmacology approaches. Eight tea phytochemicals were identified through literature mining, namely gallic acid, catechin, epigallocatechin gallate, epicatechin, epicatechin gallate (ECG), quercetin, kaempferol, and ellagic acid, based on their richness in tea leaves. Further, exploration of databases revealed 30 target proteins related to the pharmacological properties of tea compounds and multiple associated diseases. Molecular docking experiment with eight tea compounds and all 30 proteins revealed that except gallic acid all other seven phytochemicals had potential inhibitory activities against these targets. The docking experiment was validated by comparing the binding affinities (Kcal mol −1) of the compounds with known drug molecules for the respective proteins. Further, with the aid of the application of statistical tools (principal component analysis and clustering), we identified two major clusters of phytochemicals based on their chemical properties and docking scores (Kcal mol −1). Pharmacophore analysis of these clusters revealed the functional descriptors of phytochemicals, related to the ligand-protein docking interactions. Tripartite network was constructed based on the docking scores, and it consisted of seven tea phytochemicals (gallic acid was excluded) targeting five proteins and ten associated diseases. Epicatechin gallate (ECG)-hepatocyte growth factor receptor (PDB id 1FYR) complex was found to be highest in docking performance (10 kcal mol −1). Finally, molecular dynamic simulation showed that ECG-1FYR could make a stable complex in the near-native physiological condition.
2017 31st International Conference on Advanced Information Networking and Applications Workshops (WAINA), 2017
Melanoma is one of those skin cancers whichcan be fatal. So, the segmentation of lesions from the... more Melanoma is one of those skin cancers whichcan be fatal. So, the segmentation of lesions from the digitalimages becomes a crucial step in analysis and diagnosis of askin cancer using image processing techniques. This workproposes a technique for automatic segmentation of lesionfrom the digital dermoscopic images using adaptive thresholdmaking the process invariant and robust. The statisticalfeatures like standard deviation and mean are used topreprocess and segment the lesions completely in an automaticmanner. The use of image processing techniques, such asaverage filtering for removal of hair and skin scales, mathematical morphology to reject the false positives havebeen successfully able to accurately segment the lesion fromthe images. The results are significant and indicate that themethod has good accuracy. An average correlation of 90% andaverage overlapping score of 83% has been obtained.
2018 4th International Conference on Computational Intelligence & Communication Technology (CICT), 2018
Melanoma can prove fatal if not diagnosed at early stage. Computer aided identification of diseas... more Melanoma can prove fatal if not diagnosed at early stage. Computer aided identification of diseases can equip normal people in performing a screening test of diseases. The accurate lesion segmentation plays a crucial role in correct diagnosis of skin diseases. This work proposes a skin lesion segmentation method using statistical analysis and bit plane slicing. Hole filling operation is competent enough to sufficiently reject the noisy pixels from the finally segmented image. The results of skin lesion segmentation obtained from the proposed algorithm has been compared with the annotated images available with the database. The results arepresented in form of overlapping score and correlation coefficient. An average overlapping score and correlation coefficient of 91.59% and 92.07%, respectively, is obtained from the proposed algorithm. Also, an image based performance analysis of segmented lesion has been done and an average sensitivity of 94.33% has been achieved. The results are convincing and suggests that the proposed work can be used for some real-time application.
Exponential development into ICT and Web technology has had significant effect upon business & in... more Exponential development into ICT and Web technology has had significant effect upon business & infrastructure distribution structures of the current global economy. Electronic -Hospital Management Systems (EHMS) offer benefits of streamlined procedures, efficient compliance & tracking, quality patient service, strict cost containment and expanded efficiency. Healthcare Insurance Portability & Accountability Act ( HIPAA) provisions, that have established standard of healthcare sector in management of medical reports as well as protection of patient details. The research focused on identifying success metrics for Hospital Information Systems (HIS), summing up current widely accepted guidelines & procedures such as Health Level Seven (HL7) requirements for shared communications communication, HIS elements, etc. For several customized variants of E-HMS Systems & HIS upon marketplace, a basic module edition of E-HMS was meant to offer simple understanding to analysts and business special...
This dissertation is composed of two essays. In the first essay, using a panel of establishments ... more This dissertation is composed of two essays. In the first essay, using a panel of establishments from the Annual Survey of Industries (ASI), I study the impact of the 1991 trade liberalization episode in India on the employment share of women. Contrary to the predictions of a taste-based discrimination model, I find that establishments exposed to larger output tariff reductions and import competition reduced the share of female workers. I also I would like to thank my advisor Chinhui Juhn without whom this work would not have been possible. Her guidance at every step, enthusiastic discussions and painstaking corrections have been invaluable contributions. I would also like to thank her for the financial assistance provided by her to collect data for this work. She has taught me to express my ideas in a logical and coherent manner. I would also like to thank Aimee Chin for always being there and giving me the perfect sets of advises both on the professional and personal front. She introduced me to the field of research in empirical microeconomics. I am grateful to her for her patient advise on all matters. I thank Elaine Liu for pushing me hard and making me do my best. I am grateful to her for teaching me to work in an organized fashion. I thank all my dissertation committee members for their comments, corrections and suggestions throughout the course of this work.
Increasing technology, globalization and several other external connections should render medical... more Increasing technology, globalization and several other external connections should render medical tourism a large part of the rise of global medical treatment. There is extensive proof that healthcare organizations order medical travel agencies to find vendors that are trustworthy and to allow trouble-free travel arrangements to prevent critical preparations. For international care, such facilitators play a significant role in including prospective patients in one nation and medical providers in another. To date, literature on medical tourism has concentrated mostly exclusively on doctors and healthcare professionals. Otherwise, there was no scientific knowledge of the important contribution by Medical Travel Enabler to the health care industry. The moderating role of medical travel facilitators will also be discussed because of the increasing number of hospitals travelers. This paper explores or to what degree the medical tourism facilitators help the regional culture in medical to...
Proceedings of the 2nd International Conference on Applications of Intelligent Systems, 2019
Melanoma is a fatal skin anomaly which can be treated if diagnosed under benign condition. The ac... more Melanoma is a fatal skin anomaly which can be treated if diagnosed under benign condition. The accuracy of cancer detection depends directly on the accuracy of lesion segmentation. This work proposes an imaging method for lesion segmentation from dermoscopic images using inpainting, edge detection and intensity based threshold. The use of mathematical morphological operations has been done to remove noisy pixels post segmentation. The use of proposed techniques has made the method less complex and computationally efficient and can work in real-time. An average Jaccard index value of 89.2383% and correlation coefficient of 92.5271% has been achieved using the proposed method. The results are convincing and guides in the direction of usage of proposed algorithm as subset of some real time application for melanoma detection.
2016 Ninth International Conference on Contemporary Computing (IC3), 2016
Exudates are one of the abnormalities present on the retina which can be used in identification o... more Exudates are one of the abnormalities present on the retina which can be used in identification of diseases like Diabetic Retinopathy and Macular Edema. There arises a need for automated and correct segmentation of exudates from fundus images. This paper proposes an automated computer vision technique for efficient exudates segmentation from fundus images. The proposed method segments the exudates using an adaptive intensity based threshold which is selected by strategically combining first order statistical parameters and local thresholding method. The proposed technique correctly detects exudates from the fundus images with an average computation time of 9 seconds. The proposed method is computationally strong and can be used in image processing based applications for diagnosis of ocular diseases. Proposed Algorithm Retinal exudates are lipid residues that leak from damaged capillaries and commonly seen in diabetic retinopathy, retinal vein occlusions and choroid neo-vascular membranes. Exudates may be considered small regions of bright yellow color in the eye which can be rich in protein and fat.
Using a panel of establishments from the Annual Survey of Industries (ASI), I study the impact of... more Using a panel of establishments from the Annual Survey of Industries (ASI), I study the impact of the 1991 trade liberalization episode in India on the employment share of women. Contrary to the predictions of a taste-based discrimination model, I find that establishments exposed to larger output tariff reductions and import competition reduced the share of female workers. I also find that input tariff reductions neither raised nor reduced female employment share. The negative association between output tariff reductions and female employment appears to be driven by two factors. First, establishments facing larger output tariff declines engaged in more skill-upgrading which worked against women (who are less skilled in terms of measured education). Second, establishments facing larger tariff declines increased the number of shifts per worker. Since women in India are prohibited by law from working long hours and night shifts, this hours-constraint appears to have reduced relative employment of women. I find this effect to be particularly large among “big and private” establishments. This paper is the first to provide empirical evidence of how a well intentioned policy of limiting female work hours might have unintended side effects. JEL: D3, F15,J16
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